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Hire Dr. Sara C.

United Kingdom

Biology/Life Sciences Expert with a Strong Background in Cell Culture and Molecular Biology

Profile Summary

I am involved in different research projects regarding the study of liver inflammation and fibrosis. At the moment I am writing an article concerning my principal project and regarding the study of LPS-induced TNF-α factor (LITAF) transcription factor in NAFLD pediatric patients. The study includes in vitro models of hepatic stellate cells which have been used to investigate the role of LITAF in pro-inflammatory and pro-fibrogenic phenotype development. Other projects in which I am involved comprise the study of FAK in cancer liver development, the identification of novel SNPs in NAFLD pediatric patients, the epigenetic regulation in NAFLD and the analysis of different potential non-invasive biomarkers for liver damage in NAFLD. Lately, I spent 3 months (from October 2014 to December 2014) at the UCL, Institute of Liver and Digestive Health, London, UK. I was granted by EASL (European Association for the Study of the Liver) Sheila Sherlock/Andrew Burroughs Short-term Training Fellowship 2014 for the project entitled “Cancer stem cell pattern along the transition from fibrosis to HCC”. During this time I learned to isolate human hepatic stellate cells from fresh liver tissues. I have a strong background in cell culture and molecular biology and in past projects I worked in the field muscle differentiation and molecular mechanisms of cell-cell adhesion. I also have been involved in a molecular immunology project studying the occurrence of somatic mutations in immunoglobulins’ variable region upon bacterial endotoxins challenge.

Subject Matter Expertise

• ☆ Biology/Life Sciences
• ☆ Biochemistry
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Epigenetics
• ☆ Mutagenesis
• ☆ Gastroenterology & Hepatology
• ☆ Hepatitis
• ☆ Inflammation
• ☆ Metabolism & Metabolic Disease
• ☆ Technical & Scientific Writing
• ☆ Audio Transcription

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

Postdoctoral Research Fellow

Ospedale Pediatrico Bambino Gesu

June 2011 - Present

EASL (European Association for the Study of the Liver) Sheila Sherlock/Andrew Burroughs Short-term Training Fellowship 2014,

UCL, Institute of Liver and Digestive Health, London, UK

September 2014 - November 2014

Doctoral Research Fellow

Ospedale Pediatrico Bambino Gesu

January 2008 - May 2011

Research Fellow –

Ospedale Pediatrico Bambino Gesu

January 2007 - December 2007

Education

PhD Immunology and Applied Biotechnology (Interfaculty (Medicine-Biology))

Universita degli Studi di Roma Tor Vergata

October 2007 - May 2011

PhD Immunology and Applied Biotechnology

University of Rome “Tor Vergata”, Interfaculty, Rome, Italy

September 2007 - April 2011

Master Degree in Biology (Department of Mathematics, Physics and Natural Scieces, degree program in Biological Sciences: specialization in Molecular Biology)

Universita degli Studi di Roma La Sapienza

October 1996 - July 2005

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Miccheli A, Capuani G, Marini F, Tomassini A, Praticò G, Ceccarelli S, Gnani D, Baviera G, Alisi A, Putignani L, Nobili V, International journal of obesity (2005), 2015 .

Jahnel J, Zöhrer E, Alisi A, Ferrari F, Ceccarelli S, De Vito R, Scharnagl H, Stojakovic T, Fauler G, Trauner M, Nobili V, Journal of pediatric gastroenterology and nutrition, 2015 .

Panera N, Ceccarelli S, Nobili V, Alisi A, Hepatology (Baltimore, Md.), 2015 .

Ceccarelli S, Nobili V, Alisi A, World journal of gastroenterology : WJG, 2014, vol. 20, no. 44, pp. 16443-16451 .

Panera N, Gnani D, Crudele A, Ceccarelli S, Nobili V, Alisi A, World journal of gastroenterology : WJG, 2014, vol. 20, no. 41, pp. 15079-15086 .

Alisi A, Nobili V, Ceccarelli S, Panera N, De Stefanis C, De Vito R, Vitali R, Bedogni G, Balsano C, Cucchiara S, Stronati L, Expert review of molecular diagnostics, 2014, vol. 14, no. 6, pp. 763-771 .

Pastore A, Alisi A, di Giovamberardino G, Crudele A, Ceccarelli S, Panera N, Dionisi-Vici C, Nobili V, International journal of molecular sciences, 2014, vol. 15, no. 11, pp. 21202-21214 .

Panera N, Ceccarelli S, De Stefanis C, Nobili V, Alisi A, Hepatology (Baltimore, Md.), 2013, vol. 58, no. 3, pp. 1185 .

Frasinariu OE, Ceccarelli S, Alisi A, Moraru E, Nobili V, Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2013, vol. 45, no. 7, pp. 543-551 .

Alisi A, Ceccarelli S, Panera N, Prono F, Petrini S, De Stefanis C, Pezzullo M, Tozzi A, Villani A, Bedogni G, Nobili V, PloS one, 2013, vol. 8, no. 6, pp. e67160 .

Vella S, Gnani D, Crudele A, Ceccarelli S, De Stefanis C, Gaspari S, Nobili V, Locatelli F, Marquez VE, Rota R, Alisi A, International journal of molecular sciences, 2013, vol. 14, no. 12, pp. 24154-24168 .

Ceccarelli S, Panera N, Gnani D, Nobili V, International journal of molecular sciences, 2013, vol. 14, no. 4, pp. 8437-8455 .

Fierabracci A, Cascioli S, Ceccarelli S, Nobili V, Journal of hepatology, 2012, vol. 57, no. 6, pp. 1398-9; author reply 1399-400 .

Alisi A, Ceccarelli S, Nobili V, Expert opinion on medical diagnostics, 2012, vol. 6, no. 5, pp. 377-380 .

De Vito R, Alisi A, Masotti A, Ceccarelli S, Panera N, Citti A, Salata M, Valenti L, Feldstein AE, Nobili V, International journal of molecular medicine, 2012, vol. 30, no. 1, pp. 49-56 .

Alisi A, Ceccarelli S, Panera N, Nobili V, Frontiers in cellular and infection microbiology, 2012, vol. 2, pp. 132 .

Alisi A, Pastore A, Ceccarelli S, Panera N, Gnani D, Bruscalupi G, Massimi M, Tozzi G, Piemonte F, Nobili V, International journal of molecular sciences, 2012, vol. 13, no. 2, pp. 2276-2289 .

Ceccarelli S, Panera N, Alisi A, Nobili V, Hepatology (Baltimore, Md.), 2011, vol. 54, no. 4, pp. 1484-5; author reply 1485-6 .

Rosado MM, Picchianti Diamanti A, Cascioli S, Ceccarelli S, Caporuscio S, D'Amelio R, Carsetti R, Lagana B, International journal of immunopathology and pharmacology, 2011, vol. 24, no. 4, pp. 983-991 .

Aranburu A, Ceccarelli S, Giorda E, Lasorella R, Ballatore G, Carsetti R, Journal of immunology (Baltimore, Md. : 1950), 2010, vol. 185, no. 12, pp. 7293-7301 .

Ballarò C, Ceccarelli S, Tiveron C, Tatangelo L, Salvatore AM, Segatto O, Alemà S, EMBO reports, 2005, vol. 6, no. 8, pp. 755-761 .