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Hire Sara A.

Colombia

USD 85 /hr

Director of Preclinical & Translational studies / Non-Clinical Pharmacology / Project Manager / Medical Research

Profile Summary

Experienced scientific leader with over a decade of expertise in the design, execution, and management of preclinical and translational studies for drug development. Demonstrated expertise leading diverse projects across all stages of non-clinical development, spanning proof-of-concept, mechanisms of action, identifying biomarkers, non-clinical pharmacology, toxicology, and safety studies, with hands-on expertise in a wide range of laboratory techniques, and demonstrated expertise in designing and conducting complex in-vivo and in-vitro experiments, with deep understanding of animal welfare, ethical standards, and regulatory frameworks. Proficient in translating intricate scientific concepts and experimental data into actionable insights for clinical development. Proven track record of cross-functional team leadership, technical staff training, and stakeholder collaboration. Accomplished communicator with a robust publication record, and experience mentoring scientific talent.

Subject Matter Expertise

• ☆ Biochemistry
• ☆ Biochemical Assays
• ☆ Apoptosis
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Neuroscience
• ☆ Neurophysiology
• ☆ Neuropharmacology
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Biomarker Discovery
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Veterinary Medicine
• ☆ Veterinary Pathology
• ☆ Drug Development
• ☆ Small Molecule Drug Development
• ☆ Preclinical ADME/PK/PD
• ☆ Preclinical Research
• ☆ Preclinical Pharmacology
• ☆ In vitro Preclinical Toxciology
• ☆ In vivo Preclinical Toxicology
• ☆ Investigational New Drug (IND) Application Consulting
• ☆ Pharmaceutical Regulatory Affairs
• ☆ Drug Efficacy Testing
• ☆ Bioavailability
• ☆ Medical Imaging/Radiology
• ☆ Human Biology
• ☆ Endocrinology
• ☆ Diabetes
• ☆ Medical X-Ray
• ☆ Electrocardiogram (ECG)
• ☆ Ultrasound
• ☆ Diagnostic Radiology
• ☆ Traditional Medicine
• ☆ Psychoactive Drugs
• ☆ Internal Medicine
• ☆ Zoonoses
• ☆ Medical Sciences
• ☆ Metabolism & Metabolic Disease

Services

• Writing

Writing Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing, Newswriting, Audio Transcription, General Proofreading & Editing, Translation

Work Experience

Head of In-vivo research

Neuro-Sys

September 2024 - March 2025

Director of Preclinical Studies

Carvin medicines

November 2021 - April 2024

Postdoctoral Researcher

Tel Aviv University

October 2018 - May 2022

Principal Lecturer

Universidad del Valle de Mexico - UVM

August 2017 - December 2018

Invited Researcher

University of Barcelona

February 2018 - July 2018

Professor's assistant

Universidad Nacional Autonoma de México

January 2013 - January 2017

Education

Doctor of Science

Universidad Nacional Autónoma de México - UNAM

August 2014 - July 2018

M.Sc (Master of Science)

Universidad Nacional Autónoma de México - UNAM

August 2012 - July 2014

Doctor of Veterinary Medicine

Universidad Nacional de Colombia

August 2003 - December 2009

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Sara Arciniegas Ruiz, Ido Rippin, Hagit Eldar-Finkelman(2022). Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy . Cells. 11. (10). p. 1618. {MDPI} {AG}

Sara Melisa Arciniegas Ruiz, Ido Rippin, Hagit Eldar-Finkelman (2022). Prospects in GSK-3 Signaling: From Cellular Regulation to Disease Therapy . Cells.

Ido Rippin, Netaly Khazanov, Shirley Ben Joseph, Tania Kudinov, Eva Berent, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Laura Levy, Arie Gruzman, Hanoch Senderowitz, et al.(2020). Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site . International Journal of Molecular Sciences. 21. (22). p. 8709. {MDPI} {AG}

Ido Rippin, Netaly Khazanov, Shirley Ben Joseph, Tania Kudinov, Eva Berent, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Laura Levy, Arie Gruzman, Hanoch Senderowitz, et al. (2020). Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site . International Journal of Molecular Sciences.

Sara Melisa Arciniegas Ruiz, Lilia Gutiérrez Olvera, Sara del Carmen Caballero Chacón, Dinorah Vargas Estrada(2015). Pharmacokinetics of an oral extended-release formulation of doxycycline hyclate containing acrylic acid and polymethacrylate in dogs . American Journal of Veterinary Research. 76. (4). p. 367--372. American Veterinary Medical Association ({AVMA})

Sara Melisa Arciniegas Ruiz, Lilia Gutiérrez Olvera, María Josefa Bernad Bernad, Sara del Carmen Caballero Chacón, Dinorah Vargas Estrada(2015). Comparative pharmacokinetics of a new oral long-acting formulation of doxycycline hyclate: A canine clinical trial . European Journal of Pharmaceutical Sciences. 80. p. 9--15. Elsevier {BV}