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USD 25 /hr

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☆☆☆☆☆

Hire Dr. Sai Manohar C.

India

USD 25 /hr

Author and Scientist, modeling drugs and multifunctional materials | Expert in DFT & MD

Profile Summary

Scientific researcher with a PhD in Computational chemistry. Expertise in analyzing data, writing and publishing scientific articles. My primary research: Metabolic profiling of small molecule kinase inhibitors to optimize bioavailability; Drug repurposing of novel quinoline analogues as COX-2 inhibitors; Optimizing nano-piezocomposites as synthetic bone materials; DFT Simulations to model sensors for theranostic applications and hypothyroidsm; Study of ion conductive polymers and electrochemical catalysts for fuel cells. My collaborative research: Simulations to support the design and fabrication of solar cells, pesticide sensors, and diagnostics for HIV and dopamine optimized via immunology, photonics and microfluidics; Probing effective therapeutics for Covid-19 by repurposing drugs, in silico evaluation of potent bio-active components and AI for screening compounds My passions: Sports blogger on tennis, cricket and soccer (Internship and voted for attracting mileage); Story and scriptwriter, University theatre (A dozen plays across social, mythological and thriller genres); Content writer, Editor, Published author

Subject Matter Expertise

• ★ Molecular Modeling
• ★ Drug Design
• ☆ Materials Science & Engineering
• ☆ Nanotechnology
• ☆ Thermodynamics
• ☆ Drug Development
• ☆ Drug-Drug Interactions
• ☆ Technical & Scientific Writing

Services

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Product Development Formulation

Work Experience

Science Editor

JoVE (Journal of Visualized Experiments)

February 2021 - August 2023

Chemical Research Associate

CSIR Direct-SRF

April 2019 - November 2019

Chemical Research Associate/Scientist

Sankura Science exchange program, JAIST, Japan

August 2019 - August 2019

Education

Software engineering for Data Science

Indian Institute of Information Technology, Hyderabad - India

October 2021 - September 2022

PhD

Sri Sathya Sai Institute of higher learning

March 2015 - November 2019

Master of Philosophy (Department of Chemistry)

Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam Campus Department of Chemistry

June 2013 - February 2015

M.Sc (Department of Chemistry)

Sri Sathya Sai Institute of Higher Learning, Prasanthi Nilayam Campus Department of Chemistry

June 2010 - April 2012

Certifications

• Postgraduate certificate Program

  IIIT-Hyderabad

  September 2022 - Present

Publications

JOURNAL ARTICLE

Aditya Dileep Kurdekar, Chelli Sai Manohar, L. A. Avinash Chunduri, Mohan Kumar Haleyurgirisetty, Indira K. Hewlett, Venkataramaniah Kamisetti(2020). Computational design and clinical demonstration of a copper nanocluster based universal immunosensor for sensitive diagnostics . Nanoscale Advances. Royal Society of Chemistry ({RSC})

Sai Manohar, Chelli and Gupta, Parth and Belliraj, Siva Kumar(2019). An in silico design of bioavailability for kinase inhibitors evaluating the mechanistic rationale in the CYP metabolism of erlotinib . Journal of Molecular Modeling. 25. (3). p. 65.

Chelli, S.M., Gupta, P., Belliraj, S.K.(2019). An in silico design of bioavailability for kinase inhibitors evaluating the mechanistic rationale in the CYP metabolism of erlotinib . Journal of Molecular Modeling. 25. (3).

Hariharan, A., Chelli, S.M., Muthukumar V, S., Belliraj, S.K., Ferrari, M., Krishna Narasimha, N., Vishnubhatla, K.C.(2019). Paper-microfluidics based SERS substrate for PPB level detection of catechol . Optical Materials. 94. p. 305-310.

Aditya Dileep Kurdekar, L. A. Avinash Chunduri, C. Sai Manohar, Mohan Kumar Haleyurgirisetty, Indira K. Hewlett, Kamisetti Venkataramaniah (2018). Streptavidin-conjugated gold nanoclusters as ultrasensitive fluorescent sensors for early diagnosis of HIV infection . Science Advances.

Sai Manohar, Chelli, Sai Pavan Chakravarthy, N., Nageswara Rao, G., Siva Kumar, B(2018). Synthesis, NLO and Theoretical modeling of the Antiinflammatory potential of six DibenzylideneCyclopentanone analogues of Curcumin. Journal of Biological and Chemical Research. 35. (2). p. 996--1008.

Manohar, Chelli Sai and Manikandan, A and Sridhar, P and Sivakumar, A and Kumar, B Siva and Reddy, Sabbasani Rajasekhara(2018). Drug repurposing of novel quinoline acetohydrazide derivatives as potent COX-2 inhibitors and anti-cancer agents . Journal of Molecular Structure. 1154. p. 437--444. Elsevier

Pradeep Kumar Badiya, Sai Gourang Patnaik, Venkatesh Srinivasan, Narendra Reddy, Chelli Sai Manohar, Raman Vedarajan, Noriyoshi Mastumi, Siva Kumar Belliraj, Sai Sathish Ramamurthy(2017). Ag-protein plasmonic architectures for surface plasmon-coupled emission enhancements and Fabry-Perot mode-coupled directional fluorescence emission . Chemical Physics Letters. 685. p. 139--145. Elsevier {BV}

Kurdekar, A.D., Chunduri, L.A.A., Chelli, S.M., Haleyurgirisetty, M.K., Bulagonda, E.P., Zheng, J., Hewlett, I.K., Kamisetti, V.(2017). Fluorescent silver nanoparticle based highly sensitive immunoassay for early detection of HIV infection . RSC Advances. 7. (32). p. 19863-19877.

Aditya Dileep Kurdekar, L. A. Avinash Chunduri, Sai Manohar Chelli, Mohan Kumar Haleyurgirisetty, Eswarappa Pradeep Bulagonda, Jiwen Zheng, Indira K. Hewlett, Venkataramaniah Kamisetti(2017). Fluorescent silver nanoparticle based highly sensitive immunoassay for early detection of {HIV} infection . {RSC} Adv. 7. (32). p. 19863--19877. Royal Society of Chemistry ({RSC})

Swayamsiddha Kar , Sai Manohar Chelli, Sai Giridhar Sarma Kandanur, Srinivas Nanduri, Siva Kumar Belliraj, and Nageswara Rao Golakoti(2017). In silico Modeling of New C-12 Substituted-14-DeoxyAndrographolide Derivatives as Potent Anticancer Leads. Journal of Pharmacology & Clinical Toxicology. 5. (4). p. 1083. SciMedCentral

Sridhar Gopal Rao, Mohammed Bilal Ismail, Easwaramoorthy Deivanayagam, Kutti Rani Srinivasalu, Siva Kumar Belliraj, Chelli Manohar(2016). Synthesis, Characterization and Antimicrobial Activities of Copper, Nickel, Cobalt, Chromium Complexes Derived from (Z)-4-Fluoro-N-(2,7-dimethylhept-6-enylidene) benzenamine . Journal of the Brazilian Chemical Society. Sociedade Brasileira de Quimica ({SBQ})

Zirconium–Cerium and Zirconium–Lanthanum complexed polyvinyl alcohol films for efficient fluoride removal from aqueous solution .