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USD 75 /hr

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Hire Dr. Sahana S.

India

USD 75 /hr

Bioinformatician/Genome Informatician (PhD) | Clinical Genomics: WGS, WES, PGx, PRS & Somatic Variant Calling Pipelines

Profile Summary

PGx expert and bioinformatician (PhD, CSIR-IGIB) with 5+ years specializing in clinical genomics and pharmacogenomics, aligned with CPIC/PharmGKB guidelines and ACMG/ClinGen standards. My doctoral research explored PGx variants and cross-ancestry allele frequencies in Indian populations (IndiGen, GUaRDIAN cohorts), published in peer-reviewed journals. I now build and troubleshoot clinical genomics pipelines end-to-end using Snakemake, Nextflow, Docker/Conda, and HPC/cloud infrastructure: WES: rare variant calling, gene coverage QC, sex/gender QC, contamination estimation PGx: variant annotation and clinical panel interpretation, CPIC/PharmGKB-aligned reporting PRS: pipeline development and production support Somatic variant calling: DRAGEN + PCGR workflows for cancer cohorts, from raw data to final report Germline analysis: CPSR-based clinical interpretation, ACMG/ClinGen-aligned variant classification AI/ML integration: collaborating with AI/ML teams to align genomic pipeline outputs with model-ready data formats Workshops & training: designed and led hands-on genomics/PGx workshops at international conferences (ISSCP 2024, ICCPP 2023) and academic institutions Comfortable across the full stack, FASTQ to VCF to clinical report, and known for chasing root causes rather than quick fixes. I write clean SOPs, generate solid QC reports, and enjoy digging into tricky edge cases most people skip.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Omics
• ☆ Genomics
• ☆ Drug Development
• ☆ Pharmacogenomics

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing

Research Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Big Data Analytics, Data Processing, Data Insights

Product Development Product Evaluation, Product Validation, Quality Assurance & Control (QA/QC)

Work Experience

Senior Bioinformatician

Wellytics Health

January 2026 - Present

Consultant

Wellytics Health

October 2025 - December 2025

Manager - Bioinformatics

Indus Health Plus Pvt Ltd

September 2024 - June 2025

Consultant - Product Genetics

Indus Health Plus Pvt Ltd

November 2023 - August 2024

Consultant

Zifo Genomics Research Institute

May 2023 - October 2023

Project Associate

CSIR - Institute of Genomics and Integrative Biology

April 2019 - March 2023

Education

PhD

CSIR - Institute of Genomics and Integrative Biology

August 2021 - July 2024

Masters of Technology

Anna University, Chennai

August 2016 - May 2018

Bachelors of Technology

Bharathidasan University

July 2012 - May 2016

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

S Sahana, Ambily Sivadas, Bani Jolly, Rahul C Bhoyar, Abhinav Jain, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, Mohit Kumar Divakar, Anushree Mishra, et al. (2024). Landscape of pharmacogenetic variants associated with non-insulin antidiabetic drugs in the Indian population . BMJ Open Diabetes Research & Care.

Mohamed Imran, Rahul C. Bhoyar, Abhinav Jain, S. Sahana, Mercy Rophina, V.R. Arvinden, Vigneshwar Senthivel, Mohit Kumar Divakar, Anushree Mishra, Bani Jolly, et al. (2024). Genetic epidemiology of monogenic dyslipidemia and statin-associated adverse drug phenotypes in Indian population from whole-genomes of 1029 self-declared healthy individuals . Human Gene.

S Sahana, Ambily Sivadas, Surabhi Rathore, Bani Jolly, Rahul C Bhoyar, Abhinav Jain, Disha Sharma, Mohamed Imran, Vigneshwar Senthilvel, Mohit Kumar Divakar, et al. (2024). The genomic landscape of CYP2D6 variation in the Indian population . Pharmacogenomics.

S. Sahana, Rahul C. Bhoyar, Ambily Sivadas, Abhinav Jain, Mohamed Imran, Mercy Rophina, Vigneshwar Senthivel, Mohit Kumar Diwakar, Disha Sharma, Anushree Mishra, et al. (2022). Pharmacogenomic landscape of Indian population using whole genomes . Clinical and Translational Science.

S Sahana, Ambily Sivadas, Mohit Mangla, Abhinav Jain, Rahul C Bhoyar, Kavita Pandhare, Anushree Mishra, Disha Sharma, Mohamed Imran, Vigneshwar Senthivel, et al. (2021). Pharmacogenomic Landscape of Covid-19 Therapies From Indian Population Genomes . Pharmacogenomics.