Profile Details

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Hire Dr. Samuel M.

Kenya

USD 40 /hr

MBChB, MCS | Bioinformatics, Computational Neuroscience, CDISC Clinical Data & AI | Medical & Technical Writer

Profile Summary

I am a medical doctor (MBChB) and general surgery registrar (MCS, College of Surgeons of East, Central and Southern Africa) who also builds tested, reproducible research software. That combination lets me read the clinical and biological question, do the analysis, and write it up clearly for scientists, clinicians, regulators or the public. How I can help your project: Medical, scientific and technical writing: manuscripts, literature and systematic reviews, plain-language summaries, CME and patient education content, grant sections, protocols, software documentation, validation reports and fact-checking of health content. Bioinformatics and genomics: NGS pipelines in Nextflow and Snakemake, germline, somatic and long-read variant calling, variant annotation and interpretation (ClinVar, IARC), GIAB benchmarking, sequence alignment, phylogenetics, protein structure (AlphaFold, ESM-2) and molecular docking. Clinical data and biostatistics: CDISC SDTM and ADaM datasets, adverse-event and laboratory safety tables, risk differences with confidence intervals, Hy's law screening, survival analysis, Bayesian inference and reproducible analysis in Python and SQL. Computational neuroscience and biomedical engineering: Hodgkin-Huxley and integrate-and-fire models, spike-train statistics, neural encoding and decoding, signal processing (ECG, FFT, digital filters), MRI and CT reconstruction physics, pharmacokinetic and physiological modelling. AI and data science: LLM applications, retrieval-augmented generation, multi-agent systems, AI and AI-agent evaluation, and data annotation of audio, medical images and clinical text. Selected open-source work (9 projects, 1,600+ automated tests, each archived on Zenodo with a DOI): - BioEng-TermBench: biomedical engineering tasks (pharmacokinetics, closed-loop insulin control, bioheat ablation) with physics-aware graders for training and evaluating AI agents, plus a CUDA GPU benchmark - NeuroSignal: drop in an EEG recording and get a validated report: aperiodic (1/f) spectral analysis, debiased connectivity, seizure-like event detection and plain-language explanations whose every number is mechanically checked - NGS Variant Pipeline: raw sequencing reads to an evidence-cited clinical variant report - Precision Onco Africa: offline multi-agent AI for TP53 cancer-variant interpretation with an AI audit layer - CDISC Clinical Trial Safety Dashboard: raw trial data to SDTM, ADaM and safety tables - NeuroSonix: multi-agent evaluation of voice-agent conversations - BioEvidence Forge: PubMed evidence monitoring with full provenance - Healthcare AI Radar and a TP53 bioinformatics pipeline Preprints (Zenodo, 2026): - Validating the graders: physics-aware rewards for AI agents on biomedical engineering tasks. doi:10.5281/zenodo.23309911 - Validation-first EEG pipelines: how synthetic benchmarks mislead, and how pre-registration catches it. doi:10.5281/zenodo.23448015 Credentials: IBM AI Engineering and Full Stack Software Developer certificates; Bioinformatics (Technical University of Denmark; UC San Diego); Computational Neuroscience (University of Washington); Foundations of Healthcare Systems Engineering (Johns Hopkins); Biomedical Imaging (EPFL); Microsoft AI Agents and AI in Healthcare. I work carefully, cite sources, keep claims precise and deliver on time. Portfolio: portfolio-sam-mbote.vercel.app | GitHub: github.com/mbote-droid | ORCID: xxxxxxxxxxxxxxxxxxx

Subject Matter Expertise

• ★ Computational Neuroscience
• ★ Bioinformatics
• ★ Clinical Trials Data Analysis
• ☆ Biostatistics
• ☆ Molecular Biology
• ☆ Omics
• ☆ Genomics
• ☆ Neuroscience
• ☆ Data Analysis
• ☆ Machine Learning
• ☆ Python
• ☆ R
• ☆ Clinical Trials
• ☆ Clinical Data Management
• ☆ Medical Writing
• ☆ Medical Content Writing
• ☆ Research Summaries & Abstracts

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, General Proofreading & Editing

Research Meta-Research, Fact Checking, Scientific and Technical Research, Systematic Literature Review

Consulting Healthcare Consulting, Scientific and Technical Consulting

Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-ML, Data Visualization, Data Cleaning

Work Experience

General Surgery Registrar (Medical Doctor)

Embu Teaching and Referral Hospital

January 2023 - December 2025

Education

Membership of the College of Surgeons (MCS), General Surgery

College of Surgeons of East, Central and Southern Africa (COSECSA)

January 2023 - December 2025

Bachelor of Medicine and Bachelor of Surgery (MBChB)

Kampala International University

September 2011 - March 2017

Certifications

• IBM AI Engineering Professional Certificate

  IBM (via Coursera)

  https://www.credly.com/users/samuel-m.1cfdf6c1

  September 2026 - Present

• IBM Full Stack Software Developer Professional Certificate

  IBM (via Coursera)

  https://www.credly.com/users/samuel-m.1cfdf6c1

  September 2026 - Present

• Fundamentals of Biomedical Imaging (MRI, CT, X-ray, Ultrasound)

  EPFL (via Coursera)

  September 2026 - Present

• Bioinformatics: Whole Genome Sequencing of Bacterial Genomes - Tools and Applications

  Technical University of Denmark (DTU) via Coursera

  September 2026 - Present

• Foundations of Healthcare Systems Engineering

  Johns Hopkins University (via Coursera)

  September 2026 - Present

• Computational Neuroscience

  University of Washington (via Coursera)

  September 2026 - Present

• Bioinformatics (Sequence Alignment, Genome Assembly, Bioinformatics Algorithms)

  University of California San Diego (via Coursera)

  September 2026 - Present

• AI Agents (agent design, tool use, orchestration, evaluation)

  Microsoft (via Coursera)

  July 2026 - Present

• Microsoft Azure AI in Healthcare

  Microsoft (via Coursera)

  July 2026 - Present

• Annotate and Analyze Objects for Vision

  coursera

  April 2026 - Present