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Hire Samantha Pixie P.

United States

USD 125 /hr

Biochemist and Biophysicist | Expert in downstream processing

Profile Summary

I bring deep knowledge of extremophile stress tolerance mechanisms to the design of biologic and microbial product formulations. I am experienced in process development for freeze-dried products, and I have a proven track record of building high throughput formulation screening platforms and associated data infrastructure.

Subject Matter Expertise

• ★ Biochemistry
• ★ Biophysics
• ★ Bioprocess Development
• ☆ Microbiology
• ☆ Agricultural Microbiology
• ☆ Biochemical Assays
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Antioxidants
• ☆ Enzyme Activity Assays
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microbial Biotechnology
• ☆ Microbial Fermentation
• ☆ Agricultural Biotechnology
• ☆ Pharmaceutical Manufacturing
• ☆ Hypothesis
• ☆ Peer Review
• ☆ Research Methodology
• ☆ Literature Search
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Science Communication
• ☆ Scientific Proofreading & Editing

Services

• Writing
• Research
• Consulting
• Product Development

Writing Technical Writing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Product Development Formulation, Stability/Shelf Life Testing

Work Experience

Scientist II

Pivot Bio (United States)

March 2022 - June 2025

Coordinating Editor of Biochemistry/Schepartz Lab Manager

UC Berkeley

October 2020 - March 2022

Postdoctoral Associate

UC Berkeley College of Chemistry

January 2020 - October 2020

Postdoctoral Associate

Yale University

May 2019 - December 2019

Education

PhD (Chemistry)

University of North Carolina at Chapel Hill

August 2014 - April 2019

BS (Chemistry)

California Institute of Technology

October 2010 - June 2014

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2024). Polyextremophile engineering: a review of organisms that push the limits of life . FRONTIERS IN MICROBIOLOGY.

(2021). Cytosolic Delivery of Argininosuccinate Synthetase Using a Cell-Permeant Miniature Protein . ACS CENTRAL SCIENCE.

(2021). Dried Protein Structure Revealed at the Residue Level by Liquid- Observed Vapor Exchange NMR . BIOCHEMISTRY.

(2020). Toxicity and Immunogenicity of a Tardigrade Cytosolic Abundant Heat Soluble Protein in Mice . Frontiers in Pharmacology.

Piszkiewicz S, Pielak GJ(2019). Protecting Enzymes from Stress-Induced Inactivation . Biochemistry.

Piszkiewicz S, Gunn KH, Warmuth O, Propst A, Mehta A, Nguyen KH, Kuhlman E, Guseman AJ, Stadmiller SS, Boothby TC, et al.(2019). Protecting activity of desiccated enzymes . Protein science : a publication of the Protein Society.

McAvoy CZ, Siegel A, Piszkiewicz S, Miaou E, Yu M, Nguyen T, Moradian A, Sweredoski MJ, Hess S, Shan SO(2018). Two distinct sites of client protein interaction with the chaperone cpSRP43 . The Journal of biological chemistry.

Boothby TC, Tapia H, Brozena AH, Piszkiewicz S, Smith AE, Giovannini I, Rebecchi L, Pielak GJ, Koshland D, Goldstein B(2017). Tardigrades Use Intrinsically Disordered Proteins to Survive Desiccation . Molecular cell.

Piszkiewicz S, Kirkbride EA, Doreng-Stearns N, Henderson BR, Lenker MA, Tang E, Kawashiri LH, Nichols CS, Moore SC, Sogo SG(2013). Molecularly-imprinted nanoparticles that recognize Naja mossambica cytotoxins: binding studies and biological effects . Chemical communications (Cambridge, England).

Nguyen TX, Jaru-Ampornpan P, Lam VQ, Cao P, Piszkiewicz S, Hess S, Shan SO(2013). Mechanism of an ATP-independent protein disaggregase: I. structure of a membrane protein aggregate reveals a mechanism of recognition by its chaperone . The Journal of biological chemistry.

BOOK CHAPTER

(2016). Lab Tales: Personal Stories of Early Researchers . ACS Symposium Series.