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USD 50 /hr
Hire Dr. Rosario R.
Spain
USD 50 /hr
Chemist specialized in structural biology, with special interest in computational work and rational drug design.
Profile Summary
Subject Matter Expertise
Services
Writing
Technical Writing
Research
Market Research,
Gap Analysis,
Gray Literature Search,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Predictive Modeling,
Data Visualization,
Data Processing
Work Experience
PostdoctoralResearcher
CIC bioGUNE
October 2022 - Present
Postdoctoral Researcher
CIC bioGUNE
October 2022 - Present 
Scientific consultant
Freelance
April 2017 - Present
Postdoctoral Researcher
University of Oulu
May 2019 - May 2022
Senior Researcher
Latvian Institute of Organic Synthesis
January 2014 - March 2017
Reseach Associate
Centro Nacional de Biotecnología
January 2012 - December 2013
Reseach Associate
University of Cambridge
July 2008 - December 2011
Reseach Associate
Trinity College Dublin
July 2004 - June 2008
Visitor Scientist
Institut de Génétique et de Biologie Moléculaire et Cellulaire
April 2003 - May 2004
Reseach Associate
European Molecular Biology Organization
March 2001 - March 2003
Reseach Associate
University of Alabama at Birmingham
September 1997 - January 2001
Education
Doctor (Enginyeria Quimica)
Universitat Politècnica de Catalunya
September 1992 - October 1996
Licenciada (Organic Chemistry)
Universitat de Barcelona
October 1985 - March 1992
Certifications
Publications
JOURNAL ARTICLE
Rosario Recacha, Narasimha Anaganti, Swati Valmiki, Shahidul Islam, Steven Farber, Lloyd Ruddock, M. Mahmood Hussain (2024). Bulky hydrophobic side chains in the β1-sandwich of microsomal triglyceride transfer protein are critical for the transfer of both triglycerides and phospholipids . Journal of Biological Chemistry.
Rosario Recacha, Aatir A. Tungekar, Lloyd W. Ruddock (2023). Production of neutralizing antibody fragment variants in the cytoplasm of E. coli for rapid screening: SARS-CoV-2 a case study . Scientific Reports.
Rosario Recacha, Chi Zhang, Lloyd W. Ruddock, Antti Moilanen(2021). Efficient soluble production of folded cat allergen Fel d 1 in Escherichia coli . Protein Expression and Purification. 180. p. 105809. Elsevier {BV}
Rosario Recacha, Meredith H. Wilson, Daniel Rader, Sujith Rajan, Aidan Danoff, Richard J. White, Monica R. Hensley, Vanessa H. Quinlivan, James H. Thierer, Frederick J. Tan, et al.(2020). A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein . PLOS Genetics. 16. (8). p. e1008941. Public Library of Science ({PLoS})
(2020). A point mutation decouples the lipid transfer activities of microsomal triglyceride transfer protein . PLOS Genetics.
Santiago C, Mudgal G, Reguera J, Recacha R, Albrecht S, Enjuanes L, Casasnovas JM(2017). Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection . Scientific reports.
Recacha R, Jaudzems K, Akopjana I, Jirgensons A, Tars K(2016). Crystal structure of Plasmodium falciparum proplasmepsin IV: the plasticity of proplasmepsins . Acta crystallographica. Section F, Structural biology communications.
Rasina D, Otikovs M, Leitans J, Recacha R, Borysov OV, Kanepe-Lapsa I, Domraceva I, Pantelejevs T, Tars K, Blackman MJ, et al.(2015). Fragment-Based Discovery of 2-Aminoquinazolin-4(3H)-ones As Novel Class Nonpeptidomimetic Inhibitors of the Plasmepsins I, II, and IV . Journal of medicinal chemistry.
Recacha R, Leitans J, Akopjana I, Aprupe L, Trapencieris P, Jaudzems K, Jirgensons A, Tars K(2015). Structures of plasmepsin II from Plasmodium falciparum in complex with two hydroxyethylamine-based inhibitors . Acta crystallographica. Section F, Structural biology communications.
Recacha R, Jiménez D, Tian L, Barredo R, Gahmberg CG, Casasnovas JM(2014). Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions . Acta Crystallographica Section D: Biological Crystallography.
Fernandes H, Franklin E, Recacha R, Houdusse A, Goud B, Khan AR(2009). Structural aspects of Rab6-effector complexes . Biochemical Society transactions.
Recacha R, Boulet A, Jollivet F, Monier S, Houdusse A, Goud B, Khan AR(2009). Structural basis for recruitment of Rab6-interacting protein 1 to Golgi via a RUN domain . Structure (London, England : 1993).
Costanzo MJ, Yabut SC, Almond HR, Andrade-Gordon P, Corcoran TW, De Garavilla L, Kauffman JA, Abraham WM, Recacha R, Chattopadhyay D, et al.(2003). Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone . Journal of medicinal chemistry.
Greco MN, Hawkins MJ, Powell ET, Almond HR, Corcoran TW, de Garavilla L, Kauffman JA, Recacha R, Chattopadhyay D, Andrade-Gordon P, et al.(2002). Nonpeptide inhibitors of cathepsin G: optimization of a novel beta-ketophosphonic acid lead by structure-based drug design . Journal of the American Chemical Society.
Recacha R, Costanzo MJ, Maryanoff BE, Chattopadhyay D(2002). Crystal structure of human carbonic anhydrase II complexed with an anti-convulsant sugar sulphamate . The Biochemical journal.
Recacha R, Costanzo MJ, Maryanoff BE, Carson M, DeLucas L, Chattopadhyay D(2000). Structure of human alpha-thrombin complexed with RWJ-51438 at 1.7 A: unusual perturbation of the 60A-60I insertion loop . Acta Crystallographica Section D: Biological Crystallography.
Chattopadhyay D, Langsley G, Carson M, Recacha R, DeLucas L, Smith C(2000). Structure of the nucleotide-binding domain of Plasmodium falciparum rab6 in the GDP-bound form . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Talalaev A, DeLucas LJ, Chattopadhyay D(2000). Toxoplasma gondii adenosine kinase: expression, purification, characterization, crystallization and preliminary crystallographic analysis . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Carson M, Costanzo MJ, Maryanoff B, DeLucas LJ, Chattopadhyay D(1999). Structure of the RWJ-51084-bovine pancreatic beta-trypsin complex at 1.8 A . Acta Crystallographica Section D: Biological Crystallography.
Recacha R, Verdaguer N, Subirana JA(1997). Structure and supramolecular packing features of the dipeptide Arg-Val acetate . The journal of peptide research : official journal of the American Peptide Society.
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