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USD 50 /hr
Hire Dr. Roland J.W. M.
Netherlands
USD 50 /hr

(Bio)analytical scientist BMV & Development | Expert in Bioanalysis with 10+ years of experience. Editor-in-Chief.

Profile Summary
Subject Matter Expertise
Services
Writing Technical Writing
Research Gray Literature Search, Systematic Literature Review
Work Experience

Scientist II / Senior Scientist

Lonza Netherlands BV

December 2020 - Present

Sr. Scientist & Team Lead Bioanalytical Method Development and Validation

MLM Medical Labs GmbH

January 2018 - Present

Education

Ph.D

Bioanalytical Chemistry/Clinical chemistry

February 2008 - November 2011

M.Sc

Natural and Environmental Sciences

August 2004 - July 2006

B.Sc.

Natural and Environmental Sciences

August 2001 - July 2004

B.Sc

Analytical Chemistry

August 1990 - July 1994

Certifications
Publications
JOURNAL ARTICLE
Roland JW Meesters (2019). Welcome to the fifth Volume of Journal of Applied Bioanalysis . Journal of Applied Bioanalysis.
(2018). Urinary metabolite and lipid alterations in Colombian Hispanic women with breast cancer: A pilot study . Journal of Pharmaceutical and Biomedical Analysis.
Mónica P. Cala, Tone Frost Bathen, Julian Aldana, Jessica Medina, Julián Sánchez, José Guio, Julien Wist, Roland J. W. Meesters (2018). Multiplatform plasma metabolic and lipid fingerprinting of breast cancer: A pilot control-case study in Colombian Hispanic women . PLOS ONE.
Roland JW Meesters (2018). Welcome to the fourth volume of the Journal of Applied Bioanalysis . Journal of Applied Bioanalysis.
Roland JW Meesters(2017). Welcome to the third volume of Journal of Applied Bioanalysis . Journal of Applied Bioanalysis. 3. (1). p. 1--4. Betasciencepress Publishing
(2016). First anniversary of the Journal of Applied Bioanalysis . Journal of Applied Bioanalysis.
(2016). Bioanalytical evaluation of dried plasma spot microsampling methodologies in pharmacokinetic studies applying Acetaminophen as model drug . Journal of Applied Bioanalysis.
(2016). Bioanalytical evaluation of dried plasma spot microsampling methodologies in pharmacokinetic studies applying Acetaminophen as model drug . Journal of Applied Bioanalysis.
(2015). Welcome from the Journal of Applied Bioanalysis . Journal of Applied Bioanalysis.
(2015). Ghent Symposium on Alternative Sampling Strategies in Toxicology and Therapeutic Drug Monitoring . Journal of Applied Bioanalysis.
van der Vries, E., Stittelaar, K.J., van Amerongen, G., Veldhuis Kroeze, E.J.B., de Waal, L., Fraaij, P.L.A., Meesters, R.J., Luider, T.M., van der Nagel, B., Koch, B., et al.(2013). Prolonged Influenza Virus Shedding and Emergence of Antiviral Resistance in Immunocompromised Patients and Ferrets . PLoS Pathogens. 9. (5).
van Velzen, M., Missotten, T., van Loenen, F.B., Meesters, R.J.W., Luider, T.M., Baarsma, G.S., Osterhaus, A.D.M.E., Verjans, G.M.G.M.(2013). Acyclovir-resistant herpes simplex virus type 1 in intra-ocular fluid samples of herpetic uveitis patients . Journal of Clinical Virology. 57. (3). p. 215-221.
Meesters, R.J.(2013). Bioanalytical LC separation techniques for quantitative analysis of free amino acids in human plasma . Bioanalysis. 5. (4). p. 495-512.
Baarsma, G. S., Luider, T. M., Meesters, R. J., Missotten, T., Osterhaus, A. D., Verjans, G. M., van Loenen, F. B., van Velzen, M.(2013). Acyclovir-resistant herpes simplex virus type 1 in intra-ocular fluid samples of herpetic uveitis patients . J Clin Virol. 57. (3). p. 215-21.
Meesters, R.J.W., Hooff, G.P.(2013). State-of-the-art dried blood spot analysis: An overview of recent advances and future trends . Bioanalysis. 5. (17). p. 2187-2208.
Den Boer, E., Meesters, R.J.W., Van Zelst, B.D., Luider, T.M., Hazes, J.M.W., Heil, S.G., De Jonge, R.(2013). Measuring methotrexate polyglutamates in red blood cells: A new LC-MS/MS-based method . Analytical and Bioanalytical Chemistry. 405. (5). p. 1673-1681.
Meesters, R. J., Hooff, G. P.(2013). State-of-the-art dried blood spot analysis: an overview of recent advances and future trends . Bioanalysis. 5. (17). p. 2187-208.
Hazes, J. M. W., Heil, S. G., Luider, T. M., Meesters, R. J. W., de Jonge, R., den Boer, E., van Zelst, B. D.(2013). Measuring methotrexate polyglutamates in red blood cells: a new LC-MS/MS-based method . Analytical and Bioanalytical Chemistry. 405. (5). p. 1673-1681.
Rincón, J. P., Meesters, R. J.(2013). Evaluation of peripheral blood microsampling techniques in combination with liquid chromatography-high resolution mass spectrometry for the determination of drug pharmacokinetics in clinical studies . Drug Test Anal.
Hooff, G.P., Van Kampen, J.J.A., Meesters, R.J.W., Van Belkum, A., Goessens, W.H.F., Luider, T.M.(2012). Characterization of β-lactamase enzyme activity in bacterial lysates using MALDI-mass spectrometry . Journal of Proteome Research. 11. (1). p. 79-84.
Goessens, Wil H. F., Hooff, Gero P., Luider, Theo M., Meesters, Roland J. W., van Belkum, Alex, van Kampen, Jeroen J. A.(2012). Characterization of beta-Lactamase Enzyme Activity in Bacterial Lysates using MALDI-Mass Spectrometry . Journal of Proteome Research. 11. (1). p. 79-84.
Van Velzen, M., Van Loenen, F.B., Meesters, R.J.W., De Graaf, M., Remeijer, L., Luider, T.M., Osterhaus, A.D.M.E., Verjans, G.M.G.M.(2012). Latent acyclovir-resistant herpes simplex virus type 1 in trigeminal ganglia of immunocompetent individuals . Journal of Infectious Diseases. 205. (10). p. 1539-1543.
Den Boer, E., Heil, S.G., Van Zelst, B.D., Meesters, R.J.W., Koch, B.C.P., Te Winkel, M.L., Van Den Heuvel-Eibrink, M.M., Luider, T.M., De Jonge, R.(2012). A U-HPLC-ESI-MS/MS-based stable isotope dilution method for the detection and quantitation of methotrexate in plasma . Therapeutic Drug Monitoring. 34. (4). p. 432-439.
Meesters, R.J., Zhang, J., Van Huizen, N.A., Hooff, G.P., Gruters, R.A., Luider, T.M.(2012). Dried matrix on paper disks: The next generation DBS microsampling technique for managing the hematocrit effect in DBS analysis . Bioanalysis. 4. (16). p. 2027-2035.
Heil, S. G., Koch, B. C. P., Luider, T. M., Meesters, R. J. W., de Jonge, R., den Boer, E., te Winkel, M. L., van Zelst, B. D., van den Heuvel-Eibrink, M. M., Heil, S. G., et al.(2012). A U-HPLC-ESI-MS/MS-Based Stable Isotope Dilution Method for the Detection and Quantitation of Methotrexate in Plasma . Therapeutic Drug Monitoring. 34. (4). p. 432-439.
Stoop, M.P., Rosenling, T., Attali, A., Meesters, R.J.W., Stingl, C., Dekker, L.J., Van Aken, H., Suidgeest, E., Hintzen, R.Q., Tuinstra, T., et al.(2012). Minocycline effects on the cerebrospinal fluid proteome of experimental autoimmune encephalomyelitis rats . Journal of Proteome Research. 11. (8). p. 4315-4325.
Meesters, R.J.W., Hooff, G.P., Gruters, R., Van Kampen, J.J.A., Luider, T.M., Meesters, R.J.W., Hooff, G.P., Gruters, R., Van Kampen, J.J.A., Luider, T.M.(2012). Incurred sample reanalysis comparison of dried blood spots and plasma samples on the measurement of lopinavir in clinical samples . Bioanalysis. 4. (3). p. 237-240.
Lindemans, Jan, Luider, Theo M., Meesters, Roland J. W., de Jonge, Robert, den Boer, Ethan, Lindemans, Jan, Luider, Theo M., Meesters, Roland J. W., de Jonge, Robert, den Boer, Ethan(2011). Assessment of intracellular methotrexate and methotrexate-polyglutamate metabolite concentrations in erythrocytes by ultrafast matrix-assisted laser desorption/ionization triple quadrupole tandem mass spectrometry . Rapid Communications in Mass Spectrometry. 25. (20). p. 3063-3070.
Lindemans, Jan, Luider, Theo M., Mathot, Ron A. A., Meestersy, Roland J. W., de Jonge, Robert, den Boer, Ethan, van Klaveren, Rob J., Lindemans, Jan, Luider, Theo M., Mathot, Ron A. A., et al.(2011). Ultrafast selective quantification of methotrexate in human plasma by high-throughput MALDI-isotope dilution mass spectrometry . Bioanalysis. 3. (12). p. 1369-1378.
Meesters, R.J.W., Van Kampen, J.J.A., Scheuer, R.D., Van Der Ende, M.E., Gruters, R.A., Luider, T.M.(2011). Determination of the antiretroviral drug tenofovir in plasma from HIV-infected adults by ultrafast isotope dilution MALDI-triple quadrupole tandem mass spectrometry . Journal of Mass Spectrometry. 46. (3). p. 282-289.
Gruters, Rob, Hooff, Gero, Luider, Theo, Meesters, Roland, van Huizen, Nick(2011). Impact of internal standard addition on dried blood spot analysis in bioanalytical method development . Bioanalysis. 3. (20). p. 2357-2364.
Meesters, R., Hooff, G., Van Huizen, N., Gruters, R., Luider, T.(2011). Impact of internal standard addition on dried blood spot analysis in bioanalytical method development . Bioanalysis. 3. (20). p. 2357-2364.
Hooff, G.P., Meesters, R.J.W., Van Kampen, J.J.A., Van Huizen, N.A., Koch, B., Al Hadithy, A.F.Y., Van Gelder, T., Osterhaus, A.D.M.E., Gruters, R.A., Luider, T.M.(2011). Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate-a validated assay for the clinic . Analytical and Bioanalytical Chemistry. 400. (10). p. 3473-3479.
Meesters, R.J.W., Den Boer, E., Mathot, R.A.A., De Jonge, R., Van Klaveren, R.J., Lindemans, J., Luider, T.M.(2011). Ultrafast selective quantification of methotrexate in human plasma by high-throughput MALDI-isotope dilution mass spectrometry . Bioanalysis. 3. (12). p. 1369-1378.
Meesters, R.J.W., Den Boer, E., De Jonge, R., Lindemans, J., Luider, T.M.(2011). Assessment of intracellular methotrexate and methotrexate-polyglutamate metabolite concentrations in erythrocytes by ultrafast matrix-assisted laser desorption/ionization triple quadrupole tandem mass spectrometry . Rapid Communications in Mass Spectrometry. 25. (20). p. 3063-3070.
Hooff, G.P., van Huizen, N.A., Meesters, R.J.W., Zijlstra, E.E., Abdelraheem, M., Abdelraheem, W., Hamdouk, M., Lindemans, J., Luider, T.M.(2011). Analytical investigations of toxic p-phenylenediamine (PPD) levels in clinical urine samples with special focus on MALDI-MS/MS . PLoS ONE. 6. (8).
Meesters, R.J.W., Van Kampen, J.J.A., Reedijk, M.L., Scheuer, R.D., Dekker, L.J.M., Burger, D.M., Hartwig, N.G., Osterhaus, A.D.M.E., Luider, T.M., Gruters, R.A., et al.(2010). Ultrafast and high-throughput mass spectrometric assay for therapeutic drug monitoring of antiretroviral drugs in pediatric HIV-1 infection applying dried blood spots . Analytical and Bioanalytical Chemistry. 398. (1). p. 319-328.
Meesters, R.J.W., Cornelissen, R., Van Klaveren, R.J., De Jonge, R., Den Boer, E., Lindemans, J., Luider, T.M.(2010). A new ultrafast and high-throughput mass spectrometric approach for the therapeutic drug monitoring of the multi-targeted anti-folate pemetrexed in plasma from lung cancer patients . Analytical and Bioanalytical Chemistry. 398. (7-8). p. 2943-2948.
Meesters, R.J.W., Wolfe, R.R., Deutz, N.E.P.(2009). Application of liquid chromatography-tandem mass spectrometry (LC-MS/MS) for the analysis of stable isotope enrichments of phenylalanine and tyrosine . Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 877. (1-2). p. 43-49.
Meesters, R.J.W., Duisken, M., Hollender, J.(2009). Cytochrome P450-catalysed arene-epoxidation of the bioactive tea tree oil ingredient p-cymene: Indication for the formation of a reactive allergenic intermediate? . Xenobiotica. 39. (9). p. 663-671.
Meesters, R.J.W., Duisken, M., Jähnigen, H., Hollender, J., Meesters, R.J.W., Duisken, M., Jähnigen, H., Hollender, J.(2008). Sensitive determination of monoterpene alcohols in urine by HPLC-FLD combined with ESI-MS detection after online-solid phase extraction of the monoterpene-coumarincarbamate derivates . Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 875. (2). p. 444-450.
Corvini, P.F.X., Meesters, R., Mundt, M., Schäffer, A., Schmidt, B., Schröder, H.-Fr., Verstraete, W., Vinken, R., Hollender, J.(2007). Contribution to the detection and identification of oxidation metabolites of nonylphenol in Sphingomonas sp. strain TTNP3 . Biodegradation. 18. (2). p. 233-245.
Meesters, R.J.W., Duisken, M., Hollender, J.(2007). Study on the cytochrome P450-mediated oxidative metabolism of the terpene alcohol linalool: Indication of biological epoxidation . Xenobiotica. 37. (6). p. 604-617.
Meesters, R.J.W., van Eijk, H.M.H., ten Have, G.A.M., de Graaf, A.A., Venema, K., van Rossum, B.E.J., Deutz, N.E.P.(2007). Application of liquid chromatography-mass spectrometry to measure the concentrations and study the synthesis of short chain fatty acids following stable isotope infusions . Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 854. (1-2). p. 57-62.
Schröder, H.Fr., Meesters, R.J.W.(2005). Stability of fluorinated surfactants in advanced oxidation processes - A follow up of degradation products using flow injection-mass spectrometry, liquid chromatography-mass spectrometry and liquid chromatography-multiple stage mass spectrometry . Journal of Chromatography A. 1082. (1 SPEC. ISS.). p. 110-119.
Corvini, P.F.X., Meesters, R.J.W., Schäffer, A., Schröder, H.F., Vinken, R., Hollender, J.(2004). Degradation of a nonylphenol single isomer by Sphingomonas sp. strain TTNP3 leads to a hydroxylation-induced migration product . Applied and Environmental Microbiology. 70. (11). p. 6897-6900.
Meesters, R.J.W., Schröder, H.F., Meesters, R.J.W., Schröder, H.F.(2002). Simultaneous determination of 4-nonylphenol and bisphenol A in sewage sludge . Analytical Chemistry. 74. (14). p. 3566-3574.
(1995). Das Verhalten von Atrazin und Simazin im Trinkwasseraufbereitungsprozess mittels Ozon und Ozon/UV. Vom Wasser.
BOOK
Meesters, R.J.W.(2015). Capillary blood collection by the finger prick practice: An alternative blood collection procedure to venipuncture . New Sampling Strategies in Toxicology and Therapeutic Drug Monitoring. p. 23-34.
Meesters, R.J.W., Schröder, H.Fr.(2004). Perfluorooctane sulfonate - A quite mobile anionic anthropogenic surfactant, ubiquitously found in the environment . Water Science and Technology. 50. (5). p. 235-242.
Stehmann, A., Meesters, R.J.W., Schröder, H.F.(2004). Mass spectrometric analytical methods for the determination of endocrine disrupting chemicals (EDCs) . Water Science and Technology. 50. (5). p. 165-171.