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Hire Dr. Rohitashw K.

United States

Profile Summary

I am determined to utilize my research experience and keen to work in an environment where I can enrich my knowledge to improve human health and environment. I have 6 years of Post Doctoral experience in medical microbiology with expertise in human fungal pathogens, fungal cell signaling pathways, and drug target identification studies. My scientific skill includes but not limited to cell based assay, Molecular Cloning, Immunoblots, Immunefluorescence, qPCR, Confocal Microscopy, biochemical assays, Hybridoma cell line generation, monoclonal antibody production, protein purifications,mammalian tissue culture, and other Molecular biology and immunological techniques.

Subject Matter Expertise

• ☆ Microbiology
• ☆ Molecular Biology
• ☆ Protein/Enzyme Engineering

Services

• Writing
• Consulting
• Data & AI
• Product Development

Work Experience

University at Buffalo School of Dental Medicine

2010 - Present

Education

Central Drug Research Institute

December 2004 - June 2010

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Rohitashw Kumar, Ornella Salvatori, Sarah Metcalfe, Margaret Vickerman, Jason G. Kay, Mira Edgerton, Aaron P. Mitchell (2020). Bacteria Modify Candida albicans Hypha Formation, Microcolony Properties, and Survival within Macrophages . mSphere.

Rohitashw Kumar, Hannah L. Norris, Chih Yean Ong, Ding Xu, Mira Edgerton(2020). Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in C. albicans and C. glabrata . Journal of Fungi. 6. (3). p. 124. {MDPI} {AG}

Rohitashw Kumar, Malabika Maulik, Ruvini U. Pathirana, Paul J. Cullen, Mira Edgerton, Michael Lorenz(2020). Sho1p Connects Glycolysis to Ras1-{cAMP} Signaling and Is Required for Microcolony Formation in Candida albicans . {mSphere}. 5. (4). American Society for Microbiology

Rohitashw Kumar, Hannah L. Norris, Chih Yean Ong, Ding Xu, Mira Edgerton (2020). Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in <i>C. albicans</i> and <i>C. glabrata</i> . Journal of Fungi.

(2019). Iron Chelator Deferasirox Reduces Candida albicans Invasion of Oral Epithelial Cells and Infection Levels in Murine Oropharyngeal Candidiasis . Antimicrobial agents and chemotherapy.

Kumar, Rohitashw, McCall, Andrew D, Edgerton, Mira(2018). Candida albicans Sfl1/Sfl2 regulatory network drives the formation of pathogenic microcolonies . PLoS pathogens. 14. (9). p. e1007316.

(2017). Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition . Scietific Reports.

(2017). Candida albicans Sap6 amyloid regions function in cellular aggregation and zinc binding, and contribute to zinc acquisition . Scietific Reports.

Rohitashw Kumar, Darpan Saraswat, Tanaya Pande, Mira Edgerton, Paul J. Cullen(2016). Signaling Mucin Msb2 Regulates Adaptation to Thermal Stress in Candida albicans . Molecular Microbiology. p. n/a--n/a. Wiley-Blackwell

Saraswat, D., Kumar, R., Pande, T., Edgerton, M., Cullen, P. J.(2016). Signaling Mucin Msb2 Regulates Adaptation to Thermal Stress in Candida albicans . Mol Microbiol.

Rohitashw Kumar, Darpan Saraswat, Swetha Tati, Mira Edgerton, G. S. Deepe(2015). Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis . Infection and Immunity. 83. (7). p. 2614--2626. American Society for Microbiology

Kumar, Rohitashw, Saraswat, Darpan, Tati, Swetha, Edgerton, Mira(2015). Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis . Infection and Immunity. 83. (7). p. 2614-2626.

Kumar, Rohitashw, Puri, Sumant, Friedman, Justin, Saraswat, Darpan, Li, Rui, Ruszaj, Donna, Edgerton, Mira(2015). Candida albicans Shed Msb2 and Host Mucins Affect the Candidacidal Activity of Salivary Hst 5 . Pathogens (Basel, Switzerland). 4. (4). p. 752-63.

Kumar, Rohitashw, Tati, Swetha, Li, Rui, Puri, Sumant, Davidow, Peter, Edgerton, Mira(2014). Histatin 5-Spermidine Conjugates Have Enhanced Fungicidal Activity and Efficacy as a Topical Therapeutic for Oral Candidiasis . Antimicrobial Agents and Chemotherapy. 58. (2). p. 756-766.

Rohitashw Kumar, Swetha Tati, Woong Sik Jang, Rui Li, Sumant Puri, Mira Edgerton, Martine Bassilana(2013). Histatin 5 Resistance of Candida glabrata Can Be Reversed by Insertion of Candida albicans Polyamine Transporter-Encoding Genes {DUR}3 and {DUR}31 . {PLoS} {ONE}. 8. (4). p. e61480. Public Library of Science ({PLoS})

Kumar, Rohitashw, Tati, Swetha, Jang, Woong Sik, Li, Rui, Puri, Sumant, Edgerton, Mira(2013). Histatin 5 Resistance of Candida glabrata Can Be Reversed by Insertion of Candida albicans Polyamine Transporter-Encoding Genes DUR3 and DUR31 . Plos One. 8. (4).

Kumar, Rohitashw, Li, Rui, Tati, Swetha, Puri, Sumant, Edgerton, Mira(2013). Candida albicans Flu1-Mediated Efflux of Salivary Histatin 5 Reduces Its Cytosolic Concentration and Fungicidal Activity . Antimicrobial Agents and Chemotherapy. 57. (4). p. 1832-1839.

Rohitashw Kumar, Sumant Puri, Sonia Chadha, Swetha Tati, Heather R. Conti, Bernhard Hube, Paul J. Cullen, Mira Edgerton, Julian R. Naglik(2012). Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 {MAPK} Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis . {PLoS} {ONE}. 7. (11). p. e46020. Public Library of Science ({PLoS})

Kumar, Rohitashw, Puri, Sumant, Chadha, Sonia, Tati, Swetha, Conti, Heather R., Hube, Bernhard, Cullen, Paul J., Edgerton, Mira(2012). Secreted Aspartic Protease Cleavage of Candida albicans Msb2 Activates Cek1 MAPK Signaling Affecting Biofilm Formation and Oropharyngeal Candidiasis . Plos One. 7. (11).

Kumar, Rohitashw, Chadha, Sonia, Saraswat, Darpan, Bajwa, Jashanjot Singh, Li, Rui A., Conti, Heather R., Edgerton, Mira(2011). Histatin 5 Uptake by Candida albicans Utilizes Polyamine Transporters Dur3 and Dur31 Proteins . Journal of Biological Chemistry. 286. (51). p. 43748-43758.

Rohitashw Kumar, Vishnu K. Tandon, Hardesh K. Maurya, Manoj K. Verma, Praveen K. Shukla(2010). {ChemInform} Abstract: {\textquotedblleft}On Water{\textquotedblright} Assisted Synthesis and Biological Evaluation of Nitrogen and Sulfur Containing Hetero-1,4-naphthoquinones as Potent Antifungal and Antibacterial Agents . {ChemInform}. 41. (39). p. no--no. Wiley-Blackwell

Rohitashw Kumar, Vishnu K. Tandon, Hardesh K. Maurya, Manoj K. Verma, Praveen K. Shukla(2010). `On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents . European Journal of Medicinal Chemistry. 45. (6). p. 2418--2426. Elsevier {BV}

Rohitashw Kumar, P.K. Shukla(2010). Amphotericin B resistance leads to enhanced proteinase and phospholipase activity and reduced germ tube formation in Candida albicans . Fungal Biology. 114. (2-3). p. 189--197. Elsevier {BV}

Kumar, Rohitashw, Tandon, Vishnu K., Maurya, Hardesh K., Verma, Manoj K., Shukla, Praveen K.(2010). 'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents . European Journal of Medicinal Chemistry. 45. (6). p. 2418-2426.

Kumar, Rohitashw, Shukla, P. K.(2010). Amphotericin B resistance leads to enhanced proteinase and phospholipase activity and reduced germ tube formation in Candida albicans . Fungal Biology. 114. (2-3). p. 189-197.

Rohitashw Kumar, Ashok K. Chaturvedi, Awanit Kumar, Praveen K. Shukla(2009). A monoclonal {IgM} directed against immunodominant catalase B of cell wall of Aspergillus fumigatus exerts anti- A. fumigatus activities . Mycoses. 52. (6). p. 524--533. Wiley-Blackwell

Kumar, Rohitashw, Chaturvedi, Ashok K., Kumar, Awanit, Shukla, Praveen K.(2009). A monoclonal IgM directed against immunodominant catalase B of cell wall of Aspergillus fumigatus exerts anti-A-fumigatus activities . Mycoses. 52. (6). p. 524-533.