Profile Details

Create Project

★★★★★

☆☆☆☆☆

★★★★★

☆☆☆☆☆

Hire Dr. Ravi P.

United States

Profile Summary

As a scientist, I bring ten years of experience in systems biology and translational oncology research with hands on experience of working with different high throughput omics platforms including NanoString, Agilent, Affymetrix and Illumina. My research has spanned the all aspects of the genomics pipeline including experimental design, sample preparation and purification, data processing, acquisition and advanced bioinformatics analyses. These include data acquisition and analyses software platforms like nSolver, GeneSpring GX, Transcriptome Analysis Console (TAC), Ingenuity Pathway Analysis and MetaCore. More recently, I successfully completed immunosequencing-based T-cell receptor (TCR) profiling of patient blood and tumor samples as part of an ongoing clinical trial on the MiSeq Platform. My extensive experience in preclinical cancer models and Patient-Derived Xenograft (PDX) models led me to create a novel chicken egg-based cancer model. Spearheading rapid concept-product transition, I developed three main products Ovotar (PDX models), Ovivo (2D-3D modeling of cell lines) and OvoQuest (Custom Bioassays) based on customer segmentation analytics data from the TMC. Presently, I work as Director of Patient-Derived Xenograft and Advanced In Vivo Models Core at the Baylor College of Medicine (BCM) to offer these products and services within Texas Medical Center (TMC). For additional details of my projects and publications please visit www.ravirameshpathak.com

Subject Matter Expertise

• ☆ Separation & Purification
• ☆ Biology/Life Sciences
• ☆ Omics
• ☆ Transcriptomics
• ☆ Biotechnology & Bioengineering
• ☆ Systems Biology
• ☆ Sales & Marketing

Services

• Writing
• Consulting
• Product Development

Work Experience

Director

Baylor College of Medicine

June 2016 - Present

Director

Baylor College of Medicine

2016 - Present

Co-Founder/CEO

Ovodex

January 2016 - March 2017

Education

Business Innovation and Entrepreneurship

University of Texas at Austin Red McCombs School of Business

2015 - 2016

Ph.D (Biotechnology)

Guru Gobind Singh Indraprastha University

2003 - 2010

M.B.A.

Symbiosis

2004 - 2006

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Jaymin J. Kathiriya, Ravi Ramesh Pathak, Alexandr Bezginov, Bin Xue, Vladimir N. Uversky, Elisabeth R.M. Tillier, Vrushank Davé(2017). Data on evolution of intrinsically disordered regions of the human kinome and contribution of {FAK}1 {IDRs} to cytoskeletal remodeling . Data in Brief. 10. p. 315--324. Elsevier {BV}

Jaymin J. Kathiriya, Ravi Ramesh Pathak, Alexandr Bezginov, Bin Xue, Vladimir N. Uversky, Elisabeth R.M. Tillier, Vrushank Davé(2017). Structural pliability adjacent to the kinase domain highlights contribution of {FAK}1 {IDRs} to cytoskeletal remodeling . Biochimica et Biophysica Acta ({BBA}) - Proteins and Proteomics. 1865. (1). p. 43--54. Elsevier {BV}

Ravi ramesh Pathak(2016). {EDITORIAL} : Imaging Mass Spectrometry: Advancing systems approaches for biological sciences . Postdoc Journal. Postdoc Journal

Annie P. Jangam, Ravi R. Pathak, Nandula Raghuram(2016). Microarray Analysis of Rice d1 ({RGA}1) Mutant Reveals the Potential Role of G-Protein Alpha Subunit in Regulating Multiple Abiotic Stresses Such as Drought, Salinity, Heat, and Cold . Frontiers in Plant Science. 7. Frontiers Media {SA}

Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi Ramesh Pathak, Devapriya Choudhury, Richard Hooley, Nandula Raghuram(2015). G-protein $\upalpha$-subunit ({GPA}1) regulates stress, nitrate and phosphate response, flavonoid biosynthesis, fruit/seed development and substantially shares {GCR}1 regulation in A. thaliana . Plant Molecular Biology. 89. (6). p. 559--576. Springer Nature

Ravi Pathak, Marc Philizaire, Shiraz Mujtaba(2015). Dichotomy in the Epigenetic Mark Lysine Acetylation is Critical for the Proliferation of Prostate Cancer Cells . Cancers. 7. (3). p. 1622--1642. {MDPI} {AG}

Navjyoti Chakraborty, Priyanka Sharma, Kostya Kanyuka, Ravi R. Pathak, Devapriya Choudhury, Richard A. Hooley, Nandula Raghuram, Sonia Osorio-Algar(2015). Transcriptome Analysis of Arabidopsis {GCR}1 Mutant Reveals Its Roles in Stress, Hormones, Secondary Metabolism and Phosphate Starvation . {PLOS} {ONE}. 10. (2). p. e0117819. Public Library of Science ({PLoS})

Vladimir N. Uversky, Vrushank Davé, Lilia M. Iakoucheva, Prerna Malaney, Steven J. Metallo, Ravi Ramesh Pathak, Andreas C. Joerger(2014). Pathological Unfoldomics of Uncontrolled Chaos: Intrinsically Disordered Proteins and Human Diseases . Chemical Reviews. 114. (13). p. 6844--6879. American Chemical Society ({ACS})

Jaymin J. Kathiriya, Ravi Ramesh Pathak, Eric Clayman, Bin Xue, Vladimir N. Uversky, Vrushank Davé(2014). Presence and utility of intrinsically disordered regions in kinases . Mol. {BioSyst}. 10. (11). p. 2876--2888. Royal Society of Chemistry ({RSC})

Ravi Ramesh Pathak, Vrushank Davé(2014). Integrating $\less$b$\greater$$\less$i$\greater$Omics$\less$/i$\greater$$\less$/b$\greater$ Technologies to Study Pulmonary Physiology and Pathology at the Systems Level . Cellular Physiology and Biochemistry. 33. (5). p. 1239--1260. S. Karger {AG}

Ravi Ramesh Pathak(2014). Protein structure and function: Methods for prediction and analysis . Postdoc Journal. Postdoc Journal

Prerna Malaney, Ravi Ramesh Pathak, Bin Xue, Vladimir N. Uversky, Vrushank Davé(2013). Intrinsic Disorder in {PTEN} and its Interactome Confers Structural Plasticity and Functional Versatility . Scientific Reports. 3. (1). Springer Nature

Ravi R. Pathak(2013). {CancerDR}: An overview of the online database for cancer drug resistance . Postdoc Journal. Postdoc Journal

Jigneshkumar Patel, Ravi R Pathak, Shiraz Mujtaba(2011). The biology of lysine acetylation integrates transcriptional programming and metabolism . Nutrition {\&} Metabolism. 8. (1). p. 12. Springer Nature

Ravi Ramesh Pathak, Sunila Lochab(2010). A method for rapid isolation of total {RNA} of high purity and yield {fromArthrospira} platensis . Canadian Journal of Microbiology. 56. (7). p. 578--584. Canadian Science Publishing

Ravi Ramesh Pathak, Suman K. Das, Devapriya Choudhury, Nandula Raghuram(2009). Genomewide bioinformatic analysis negates any specific role for Dof, {GATA} and Ag/{cTCA} motifs in nitrate responsive gene expression in Arabidopsis . Physiology and Molecular Biology of Plants. 15. (2). p. 145--150. Springer Nature

Suman K. Das, Ravi Ramesh Pathak, Devapriya Choudhury, Nandula Raghuram(2007). Genomewide computational analysis of nitrate response elements in rice and Arabidopsis . Molecular Genetics and Genomics. 278. (5). p. 519--525. Springer Nature

OTHER

Jigneshkumar Patel, Ravi Pathak, Shiraz Mujtaba(2013). The Biology of Lysine Acetylation Integrates Transcriptional Programming and Metabolism . 117--141Apple Academic Press

CONFERENCE PAPER

Vrushank Dave, Ravi R. Pathak(2012). Bioinformatic Analysis Reveals That {PTEN} Loss Confers Oncogenic Potential To Lung Epithelial Cells . American Thoracic Society

BOOK

(2006). Introduction to biotechnology . Atlantic.