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Profile Details
Subject Matter Expertise
Services
Research
Fact Checking,
Gray Literature Search,
Systematic Literature Review,
Secondary Data Collection
Work Experience
Professor & Head of the Department (retired)
Department of Human Genetics, NIMHANS, Bangalore
January 1997 - February 2017
Professor
NIMHANS
January 1997 - February 2017 
Education
Ph.D. (Microbiology and Cell Biology Laboratory)
Indian Institute of Science
August 1976 - August 1980
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Keshava, R., Muniyappa, N., Gope, R., Ramaswamaiah, A.S.(2016). Anti-cancer effects of Imperata cylindrica leaf extract on human oral squamous carcinoma cell line SCC-9 in vitro . Asian Pacific Journal of Cancer Prevention. 17. (4). p. 1891-1898.
Mitra, R., Indira Devi, B., Gope, M.L., Subbakrishna, D.K., Gope, R.(2012). Sodium butyrate modulates pRb phosphorylation and induces cell death in human vestibular schwannomas in vitro . Indian Journal of Experimental Biology. 50. (1). p. 19-27.
Mitra, R., Bhagavatula, I.D., Gope, R.(2012). BAY 61-3606, CDKi, and sodium butyrate treatments alter gene expression in human vestibular schwannomas and cause cell death in vitro . ecancermedicalscience. 6. (1).
Mazzucco, L., Borzini, P., Gope, R.(2010). Platelet-derived factors involved in tissue repair-from signal to function . Transfusion Medicine Reviews. 24. (3). p. 218-234.
Gope, M.L., Gope, R.(2009). Tyrosine phosphorylation of EGF-R and PDGF-R proteins during acute cutaneous wound healing process in mice . Wound Repair and Regeneration. 17. (1). p. 71-79.
Rohini, K., Mathivanan, J., Prabhu, P.D.A.H., Subbakrishna, D.K., Gope, M.L., Chandramouli, B.A., Sampath, S., Anandh, B., Gope, R.(2007). Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors . Molecular and Cellular Biochemistry. 300. (1-2). p. 101-111.
Gope, M.L., Gope, R.(2007). Topically applied EGF and PDGFs affect positively the co-ordinate expression of EGF and PDGF receptor genes during acute cutaneous wound-healing process . Current Science. 92. (5). p. 618-627.
Mathivanan, J., Rohini, K., Gope, M.L., Anandh, B., Gope, R.(2007). Altered structure and deregulated expression of the tumor suppressor gene retinoblastoma (RB1) in human brain tumors . Molecular and Cellular Biochemistry. 302. (1-2). p. 67-77.
Dayalan, A.H.P.P., Jothi, M., Keshava, R., Thomas, R., Gope, M.L., Doddaballapur, S.K., Somanna, S., Prabaraj, S.S., Ashwathnarayanarao, C.B., Gope, R.(2006). Age dependent phosphorylation and deregulation of p53 in human vestibular schwannomas . Molecular Carcinogenesis. 45. (1). p. 38-46.
Nalini, A., Yamini, B.K., Gayatri, N., Thennarasu, K., Gope, R.(2006). Familial Madras motor neuron disease (FMMND): Study of 15 families from southern India . Journal of the Neurological Sciences. 250. (1-2). p. 140-146.
Thomas, R., Prabhu, P.D.A.H., Mathivanan, J., Rohini, Sivakumar, D., Jayakumar, P.N., Devi, B.I., Satish, S., Sastry, K.V.R., Gope, R.(2005). Altered structure and expression of RB1 gene and increased phosphorylation of pRb in human vestibular schwannomas . Molecular and Cellular Biochemistry. 271. (1-2). p. 113-121.
Gope, M.L., Gope, R.(2003). Effect of sodium butyrate on methylation pattern of retinoblastoma (RB1) gene in human colon tumour cell line HT29 . Current Science. 84. (3). p. 430-434.
Gope, R.(2002). The effect of epidermal growth factor & platelet-derived growth factors on wound healing process . Indian Journal of Medical Research. 116. (NOV.). p. 201-206.
Gope, R., Gope, M.L., Gope, R., Gope, M.L.(1993). Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29 . Cellular and Molecular Biology. 39. (6). p. 589-597.
Wildrick, D.M., Alfaro, S.R., Gope, R., Boman, B.M.(1992). A study of chromosome 6 allele loss in human colorectal carcinomas . Anticancer Research. 12. (5). p. 1717-1719.
Gope, R., Gope, M.L.(1992). Abundance and state of phosphorylation of the retinoblastoma susceptibility gene product in human colon cancer . Molecular and Cellular Biochemistry. 110. (2). p. 123-133.
Gope, M.L., Chun, M., Gope, R.(1992). Comparative study of the expression Rb and p53 genes in human colorectal cancers, color carcinoma cell lines and synchronized human fibroblast . Molecular and Cellular Biochemistry. 110. (1).
Gope, M.L., Chun, M., Gope, R.(1991). Comparative study of the expression of Rb and p53 genes in human colorectal cancers, colon carcinoma cell lines and synchronized human fibroblasts . Molecular and Cellular Biochemistry. 107. (1). p. 55-63.
Gope, R., Gope, M.L., Thorson, A., Christensen, M., Smyrk, T., Chun, M., Alvarez, L., Wildrick, D.M., Boman, B.M.(1991). Genetic changes at the Beta-2-Adrenergic receptor locus on chromosome 5 in human colorectal carcinomas . Anticancer Research. 11. (6). p. 2047-2050.
Gope, M.L., Gope, R., Zarucki, T.(1991). Effect of dexamethasone and cycloheximide on the expression of amplified EGF-receptor gene in human A431 carcinoma cell line . Molecular and Cellular Biochemistry. 103. (2). p. 149-154.
Gope, R., Christensen, M.A., Thorson, A., Lynch, H.T., Smyrk, T., Hodgson, C., Wildrick, D.M., Gope, M.L., Boman, B.M.(1990). Increased expression of the retinoblastoma gene in human colorectal carcinomas relative to normal colonic mucosa . Journal of the National Cancer Institute. 82. (4). p. 310-314.
Dean, D.C., Gope, R., Knoll, B.J., Riser, M.E., O'Malley, B.W.(1984). A similar 5'-flanking region is required for estrogen and progesterone induction of ovalbumin gene expression . Journal of Biological Chemistry. 259. (16). p. 9967-9970.
BOOK
Mitra, R., Gope, M.L., Gope, R.(2013). Personalized genome, current status, and the future of pharmacogenomics . Omics for Personalized Medicine. p. 19-37.
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