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Hire Dr. Radoslav J.

Spain

USD 50 /hr

Senior Scientific & Strategic Consultant | Biotech, Biopharma & MedTech | Translational & R&D Decision-Making

Profile Summary

Senior scientific and strategic leader with 15+ years of international experience across academic research leadership, life sciences consulting, and biotech innovation ecosystems. Experienced in translating complex science into actionable R&D, translational, and strategic decisions for biotech, biopharma, pharma, and medical device organizations. Strong background in project and program leadership, client-facing consulting, technology assessment, and mentoring across academia and early-stage biotech.

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Omics
• ☆ Transcriptomics
• ☆ Proteomics
• ☆ Genomics
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Cell Culture
• ☆ Cell Line Engineering
• ☆ 3D Cell Culture
• ☆ Drug Discovery
• ☆ High Throughput Screening (HTS)
• ☆ Drug Target Identification
• ☆ Phenotypic Assays
• ☆ Medical Devices
• ☆ Medical Device Development
• ☆ Medical Device Design
• ☆ Wearable Technology
• ☆ Dermatology
• ☆ Skin Cancer
• ☆ Women's Health
• ☆ Breast Cancer
• ☆ Ovarian Cancer
• ☆ Gastroenterology & Hepatology
• ☆ Colorectal Cancer
• ☆ Pancreatic Cancer
• ☆ Medical Sciences
• ☆ Cancer Research
• ☆ Cancer Biology
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Instructional Materials
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ White Papers
• ☆ Textbook Content Writing
• ☆ Science Communication

Services

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Medical Writing, Technical Writing

Research Market Research, Feasibility Study, Technology Scouting, Fact Checking, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review, Secondary Data Collection

Consulting Business Strategy Consulting, Healthcare Consulting, Scientific and Technical Consulting, Regulatory Consulting

Work Experience

Group Leader

Charles University

January 2022 - Present

Postdoctoral Fellow

Yale University

December 2015 - May 2019

Postdoctoral Research Scientist

Columbia University

September 2014 - December 2015

Trainee Scientist

Charles University

October 2008 - August 2014

Education

PhD

Charles University

October 2010 - August 2014

Certifications

• Certification details not provided.

Publications

PREPRINT

Radoslav Janostiak, Lucia Csergeova (2025). Dynamic Phosphoproteomic Profiling Identifies CK2 as a Critical Survival Kinase in Quiescent Breast Cancer Cells and a Therapeutic Target for Minimal Residual Disease .

JOURNAL ARTICLE

Radoslav Janostiak, Ariadna Torres-Sanchez, Francesc Posas, Eulàlia de Nadal(2022). Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies . Cancers. 14. (5). p. 1265. {MDPI} {AG}

Radoslav Janostiak, Ariadna Torres-Sanchez, Francesc Posas, Eulàlia de Nadal (2022). Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies . Cancers.

Romi Gupta, Radoslav Janostiak, Narendra Wajapeyee(2020). Transcriptional regulators and alterations that drive melanoma initiation and progression . Oncogene. 39. (48). p. 7093--7105. Springer Science and Business Media {LLC}

Romi Gupta, Parmanand Malvi, Keshab Raj Parajuli, Radoslav Janostiak, Suresh Bugide, Guoping Cai, Lihua Julie Zhu, Michael R. Green, Narendra Wajapeyee(2020). KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity . Proceedings of the National Academy of Sciences. 117. (22). p. 12341--12351. Proceedings of the National Academy of Sciences

Gupta, R., Janostiak, R., Wajapeyee, N.(2020). Transcriptional regulators and alterations that drive melanoma initiation and progression . Oncogene.

Gupta, R., Malvi, P., Parajuli, K.R., Janostiak, R., Bugide, S., Cai, G., Zhu, L.J., Green, M.R., Wajapeyee, N.(2020). KLF7 promotes pancreatic cancer growth and metastasis by up-regulating ISG expression and maintaining Golgi complex integrity . Proceedings of the National Academy of Sciences of the United States of America. 117. (22). p. 12341-12351.

Malvi, P., Janostiak, R., Chava, S., Manrai, P., Yoon, E., Singh, K., Harigopal, M., Gupta, R., Wajapeyee, N.(2020). LIMK2 promotes the metastatic progression of triple-negative breast cancer by activating SRPK1 . Oncogenesis. 9. (8).

Parmanand Malvi, Kent W. Hunter, Radoslav Janostiak, Arvindhan Nagarajan, Guoping Cai, Narendra Wajapeyee(2019). Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression . PLOS Genetics. 15. (10). p. e1008439. Public Library of Science ({PLoS})

(2019). Anaplastic Lymphoma Kinase Confers Resistance to BRAF Kinase Inhibitors in Melanoma . iScience.

(2019). Dot Blot Analysis for Measuring Global N6-Methyladenosine Modification of RNA . Methods in molecular biology (Clifton, N.J.).

(2019). RNA Modification Regulatory Genes in DNA Damage . Methods in molecular biology (Clifton, N.J.).

Janostiak, R., Malvi, P., Wajapeyee, N.(2019). Anaplastic Lymphoma Kinase Confers Resistance to BRAF Kinase Inhibitors in Melanoma . iScience. 16. p. 453-467.

Malvi, P., Janostiak, R., Nagarajan, A., Cai, G., Wajapeyee, N.(2019). Loss of thymidine kinase 1 inhibits lung cancer growth and metastatic attributes by reducing GDF15 expression . PLoS Genetics. 15. (10).

Radoslav Janostiak, Monika Vyas, Ali Fuat Cicek, Narendra Wajapeyee, Malini Harigopal(2018). Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation . Experimental and Molecular Pathology. 105. (1). p. 41--49. Elsevier {BV}

(2018). Epigenetic Mechanisms Dictating Eradication of Cancer by Natural Killer Cells . Trends in cancer.

Bugide, S., Janostiak, R., Wajapeyee, N.(2018). Epigenetic Mechanisms Dictating Eradication of Cancer by Natural Killer Cells . Trends in Cancer. 4. (8). p. 553-566.

Janostiak, R., Vyas, M., Cicek, A.F., Wajapeyee, N., Harigopal, M.(2018). Loss of c-KIT expression in breast cancer correlates with malignant transformation of breast epithelium and is mediated by KIT gene promoter DNA hypermethylation . Experimental and Molecular Pathology. 105. (1). p. 41-49.

(2017). MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway . Cell reports.

(2017). ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility . Journal of cell science.

Luo, W., Janoštiak, R., Tolde, O., Ryzhova, L.M., Koudelková, L., Dibus, M., Brábek, J., Hanks, S.K., Rosel, D.(2017). ARHGAP42 is activated by Src-mediated tyrosine phosphorylation to promote cell motility . Journal of Cell Science. 130. (14). p. 2382-2393.

Janostiak, R., Rauniyar, N., Lam, T.T., Ou, J., Zhu, L.J., Green, M.R., Wajapeyee, N.(2017). MELK Promotes Melanoma Growth by Stimulating the NF-κB Pathway . Cell Reports. 21. (10). p. 2829-2841.

(2014). Mechanosensors in integrin signaling: the emerging role of p130Cas . European journal of cell biology.

Janoštiak, R., Pataki, A.C., Brábek, J., Rösel, D.(2014). Mechanosensors in integrin signaling: The emerging role of p130Cas . European Journal of Cell Biology. 93. (10-12). p. 445-454.

Janoštiak, R., Brábek, J., Auernheimer, V., Tatárová, Z., Lautscham, L.A., Dey, T., Gemperle, J., Merkel, R., Goldmann, W.H., Fabry, B., et al.(2014). CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics . Cellular and Molecular Life Sciences. 71. (4). p. 727-744.

(2013). CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics . Cellular and molecular life sciences : CMLS.

(2013). CAS directly interacts with vinculin to control mechanosensing and focal adhesion dynamics . Cellular and molecular life sciences : CMLS.

(2012). Dynamics and morphology of focal adhesions in complex 3D environment. Folia biologica.

Tolde, O., Rösel, D., Janoštiak, R., Veselý, P., Brábek, J.(2012). Dynamics and morphology of focal adhesions in complex 3D environment . Folia biologica. 58. (5). p. 177-184.

(2011). Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness . Molecular biology of the cell.

Janoštiak, R., Tolde, O., Brůhová, Z., Novotný, M., Hanks, S.K., Rösel, D., Brábek, J.(2011). Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness . Molecular Biology of the Cell. 22. (22). p. 4256-4267.

BOOK

Janostiak, R., Wajapeyee, N.(2019). Rna modification regulatory genes in DNA damage . Methods in Molecular Biology. 1870. p. 249-262.

Nagarajan, A., Janostiak, R., Wajapeyee, N.(2019). Dot blot analysis for measuring global n⁶-methyladenosine modification of RNA . Methods in Molecular Biology. 1870. p. 263-271.