Profile Details

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Hire Dr. Rachel H.

United States

USD 30 /hr

Cell biology research scientist with a strong background in vascular and pulmonary physiology

Profile Summary

Pulmonary physiology research scientist studying inflammation in pulmonary microvessels. My primary focus has been studying the expansion of pulmonary microvascular inflammation through confocal microscopy experiments utilizing isolated blood-perfused rodent lungs. -Intravital/ex vivo imaging studies of autologous blood-perfused rat and mouse lungs using confocal and wide-angle microscopy -In vitro gene knockdown of isolated pulmonary microvascular endothelial cells (PMVECs) -Isolation and culture of primary PMVECs -Delivery of fluorophores and reagents via micropuncture directly into single alveoli or microvessels in intact lung -PCR and development of transgenic mice genotype database (Microsoft Access) -Mouse breeding and surgery -Manuscript writing/editing and figure design

Subject Matter Expertise

• ★ Data Analysis
• ★ Print Design
• ☆ Biology/Life Sciences
• ☆ Plant Breeding & Genetics
• ☆ Molecular Biology
• ☆ PCR
• ☆ Cell Biology
• ☆ Microscopy
• ☆ Database Management
• ☆ Bioinformatics
• ☆ Inflammation

Services

• Writing
• Research
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis, Data Visualization

Work Experience

Research Assistant

University of Tennessee Health Science Center

August 2011 - Present

Undergraduate worker

St. Jude Children's Research Hospital

May 2009 - August 2011

Education

PhD (Physiology)

University of Tennessee Health Science Center

August 2011 - Present

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Escue R, Kandasamy K, Parthasarathi K. Thrombin Induces Inositol Trisphosphate-Mediated Spatially Extensive Responses in Lung Microvessels. Am J Pathol. 2017;187(4):921-935 .

Kandasamy K, Escue R, Manna J, Adebiyi A, Parthasarathi K. Changes in endothelial connexin 43 expression inversely correlate with microvessel permeability and VE-cadherin expression in endotoxin-challenged lungs. Am J Physiol Lung Cell Mol Physiol. 2015;309(6):L584-92.

Kandasamy K, Bezavada L, Escue RB, Parthasarathi K. Lipopolysaccharide induces endoplasmic store Ca2+-dependent inflammatory responses in lung microvessels. PLoS ONE. 2013;8(5):e63465.