Profile Details

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Hire Dr. Pavithra S.

France

USD 30 /hr

Profile Summary

A PhD in Biological Sciences (Specialization: Biochemistry/Biophysics) and Bachelors in Biotechnology with a strong background in protein biochemistry and hold research experience of 6+ years in the field of protein expression, purification, characterization and molecular biology as evident by publications in the top peer-reviewed journals. ✦ Energetic, enthusiastic and extroverted personality willing to work with people to bring advancements in the field of science for the betterment of the public. ✦ Excellent science communicator and speaker as exhibited by delivering scientific talks and by presenting posters in over 10 international conferences and meetings; and by teaching 2 laboratory courses to nearly 40 undergraduates for two years. ✦ Outstanding problem solving and management experience by training young researchers to complete their Master's level project. PhD project: I worked on the interface of X-ray Crystallography and Host-Pathogen interactions to understand how YopO kinase from Yersinia spp. uses actin, an important cytoskeletal protein, as a bait to phosphorylate proteins that regulate actin polymerization. Postdoctoral project: During my postdoc, I extended my research interests to yet another important cytoskeletal regulator, Microtubules, where I studied the cross-talk between actin and microtubules by using a combination of imaging and biochemical assays.

Subject Matter Expertise

• ☆ Separation & Purification
• ☆ X-Ray Crystallography
• ☆ Biochemistry
• ☆ Kinases
• ☆ Biophysics
• ☆ Protein/Enzyme Engineering
• ☆ Science Communication

Services

• Research
• Consulting
• Product Development

Work Experience

Post Doctoral Fellow

Commissariat à l’energie atomique et aux énergies alternatives (CEA) / CNRS, Grenoble,France

January 2016 - January 2018

Graduate Researcher

National University of Singapore (NUS), Singapore

July 2010 - September 2015

Teaching Assistant

National University of Singapore, Singapore

July 2011 - September 2013

Undergraduate Researcher

Anna University, Chennai, India

June 2008 - July 2009

Education

PhD (Biology)

National University of Singapore (NUS)

July 2010 - September 2015

B.Tech (Bachelors of Technology) - Biotechnology

Anna University, India

July 2005 - July 2009

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Pavithra Singaravelu, Wei Lin Lee, Sheena Wee, Umesh Ghoshdastider, Ke Ding, Jayantha Gunaratne, Jonathan M. Grimes, Kunchithapadam Swaminathan, Robert C. Robinson(2017). Yersiniaeffector protein ({YopO})-mediated phosphorylation of host gelsolin causes calcium-independent activation leading to disruption of actin dynamics . Journal of Biological Chemistry. 292. (19). p. 8092--8100. American Society for Biochemistry {\&} Molecular Biology ({ASBMB})

Pavithra Singaravelu, Wei Lin Lee, Sheena Wee, Umesh Ghoshdastider, Ke Ding, Jayantha Gunaratne, Jonathan M. Grimes, Kunchithapadam Swaminathan, Robert C. Robinson(2017). Yersiniaeffector protein ({YopO})-mediated phosphorylation of host gelsolin causes calcium-independent activation leading to disruption of actin dynamics . Journal of Biological Chemistry. 292. (19). p. 8092--8100. American Society for Biochemistry {\&} Molecular Biology ({ASBMB})

Pavithra Singaravelu, Wei Lin Lee, Sheena Wee, Bo Xue, Khay Chun Ang, Jayantha Gunaratne, Jonathan M. Grimes, Kunchithapadam Swaminathan, Robert C. Robinson(2017). Mechanisms of Yersinia {YopO} kinase substrate specificity . Scientific Reports. 7. p. 39998. Springer Nature