Parul Sood - Freelance Life Sciences Consultant in Maharashtra, India

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India

Profile Summary

Cargo crowding at actin-rich regions along axons causes local traffic jams in neurons
• Established, for the first time, specific contribution of macro-molecular crowding in initiating local traffic jams
of synaptic vesicles in neurons of both C. elegans and D. melanogaster using time lapse imaging
•Examined the implications of these traffic jams as dynamic reservoirs of vesicle along the neuronal process using 
behavioral paradigms in C. elegans

Regulation of cargo motion at stalled vesicles is important for maintaining cargo flow
• Investigated role of stationary cargo along the neuronal process in regulation of axonal transport
• Used neurodegenrative disease models to establish a correlation between regulation of axonal transport and disease pathology 
•Worked in collaboration with a team of physicists from IMSc, Chennai to model axonal transport and predict the consequences of perturbed cargo regulation at stationary cargo

Organization of microtubule and actin cytoskeleton along the neuronal process in differentiated neurons of 
C. elegans
• Used candidate gene approach to find potential cross-linkers of microtubules and actin in differentiated neurons of
C. elegans 
• Performed various pharmacological drug treatments to understand the interactions between two cytoskeletal 
components

Psychological stressors induced disease susceptibility
• Conducted a pilot study to develop new tools combining both quantitative and qualitative methods to determine the
 stress levels in random human population
• Used metabolomic and proteomic analysis for biomarker discovery
• Designed a questionnaire to determine stress level of individuals and associate it with potential psychological stressors

Short term Projects
• Reviewed roles of Indian Psychology in Psychotherapy 
• Reviewed behavioral and molecular studies related to effects of psychological stress in various disease conditions 
• Isolated and identified environmental microflora 
• Investigated intracellular trafficking of S. aureus in murine macrophages

Subject Matter Expertise

Services

Consulting
Product Development

Work Experience

Senior Research Felllow

Tata Institute of Fundamental Research

August 2012 - Present

KVPY Fellow

KVPY Scholarship

August 2008 - June 2012

KVPY Fellow

KVPY Scholarship by Govt. of India

August 2008 - June 2012

Education

PhD

Tata Institute of Fundamental Research

August 2012 - Present

Integrated Masters

National Institute of Science Education and Research

August 2007 - June 2012

Certifications

Certification details not provided.

Publications

JOURNAL ARTICLE

Parul Sood, Sushri Priyadarshini, Palok Aich, Peter Csermely(2013). Estimation of Psychological Stress in Humans: A Combination of Theory and Practice . {PLoS} {ONE}. 8. (5). p. e63044. Public Library of Science ({PLoS})

Parul Sood(2012). Psychological stressors as interventions: Good out of the evil . Frontiers in Bioscience. S4. (1). p. 43. Frontiers in Bioscience