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Italy

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Researcher of Pharmacology and Toxicology

Profile Summary

Researcher of Pharmacology at the Department of Biomedical Sciences, University of Foggia. Pharmacology Teacher, School of Medicine, Faculty of Medicine, University of Foggia, Italy. Member of Board of CLA - University Language Centre, University of Foggia. Designated by the Commission for the supervision and control of doping and for the protection of health in sports activities (Ministry of Health and Social Policies) as a referee for the evaluation of the projects presented in the framework of the research and training program / information on drugs, substances and medical practices that can be used for doping purposes and for the protection of health in sporting activities 2009. From 2004 to 2006 post-doctoral fellow for the project “Exposure to cannabinoids during brain development: neurophysiological study” (Department of Human Physiology and Pharmacology, Vittorio Erspamer, University of Rome “La Sapienza” ). Post-doctoral fellow for the project “Exposure Delta9-Tetrahydrocannabinol during brain development and adolescence: behavioural, neurochemical and neurophysiological study in rat” (Italian Ministry of Education, University and Research (MIUR). Post-doctoral fellow for the project “Non-opioid analgesics and opioids interaction” (Department of Pharmacology of Natural Substances and General Physiology, University of Rome “La Sapienza”). Designated by the "Department of Pharmaceutical Studies" of the University of Rome "La Sapienza" to teach lessons (70 hours) for a professional training course for the project: Evaluation and mapping of the ecotoxicological risk of discharges human and productive settlements and surface and deep waters in the Lazio region (project owner: Research Toxicology Center (RTC). Consultant to Technical Secretary of Italian Pharmacopeia.

Subject Matter Expertise

• ★ Psychopharmacology
• ☆ Behavioral Neuroscience
• ☆ Pharmacy Education

Services

• Writing
• Research
• Consulting

Writing Clinical Trial Documentation, Technical Writing

Research Fact Checking, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Work Experience

Ricercatore confermato

Università degli Studi di Foggia

March 2007 - Present

Education

Università degli Studi di Roma La Sapienza

November 1988 - February 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). Depressive-like phenotype evoked by lifelong nutritional omega-3 deficiency in female rats: Crosstalk among kynurenine, Toll-like receptors and amyloid beta oligomers . Brain, Behavior, and Immunity. 87. p. 444-454.

(2020). Ketamine administration induces early and persistent neurochemical imbalance and altered NADPH oxidase in mice . Progress in Neuro-Psychopharmacology and Biological Psychiatry. 96.

(2020). Postnatal Antioxidant and Anti-inflammatory Treatments Prevent Early Ketamine-Induced Cortical Dysfunctions in Adult Mice . Frontiers in Neuroscience. 14.

(2019). Early Celastrol Administration Prevents Ketamine-Induced Psychotic-Like Behavioral Dysfunctions, Oxidative Stress and IL-10 Reduction in The Cerebellum of Adult Mice . Molecules. 24. (21). p. 3993. {MDPI} {AG}

(2019). Early Celastrol Administration Prevents Ketamine-Induced Psychotic-Like Behavioral Dysfunctions, Oxidative Stress and IL-10 Reduction in The Cerebellum of Adult Mice . Molecules.

(2019). Early celastrol administration prevents ketamine-induced psychotic-like behavioral dysfunctions, oxidative stress and IL-10 reduction in the cerebellum of adult mice . Molecules. 24. (21).

(2018). Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in naïve and Aβ-treated female rats . Biochemical Pharmacology. 155. p. 326-335.

(2018). Sub-chronic celecoxib prevents soluble beta amyloid-induced depressive-like behaviour in rats . Journal of Affective Disorders. 238. p. 118-121.

(2018). Celecoxib Prevents Cognitive Impairment and Neuroinflammation in Soluble Amyloid β-treated Rats . Neuroscience. 372. p. 58-73.

(2018). N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype . Pharmacological Research. 129. p. 526-534.

(2017). Visceral fat dysfunctions in the rat social isolation model of psychosis . Frontiers in Pharmacology. 8. (NOV).

Schiavone, S. and Tucci, P. and Mhillaj, E. and Bove, M. and Trabace, L. and Morgese, M.G.(2017). Antidepressant drugs for beta amyloid-induced depression: A new standpoint? . Progress in Neuro-Psychopharmacology and Biological Psychiatry. 78. p. 114-122. Elsevier Inc.

(2017). Early Loss of Blood-Brain Barrier Integrity Precedes NOX2 Elevation in the Prefrontal Cortex of an Animal Model of Psychosis . Molecular Neurobiology. 54. (3). p. 2031-2044.

(2017). Lifelong Nutritional Omega-3 Deficiency Evokes Depressive-Like State Through Soluble Beta Amyloid . Molecular Neurobiology. 54. (3). p. 2079-2089.

(2017). Antidepressant drugs for beta amyloid-induced depression: A new standpoint? . Progress in Neuro-Psychopharmacology and Biological Psychiatry. 78. p. 114-122.

(2016). The NADPH oxidase NOX2 as a novel biomarker for suicidality: Evidence from human post mortem brain samples . Translational Psychiatry. 6. (5).

(2016). Chronic psychosocial stress impairs bone homeostasis: A study in the social isolation reared rat . Frontiers in Pharmacology. 7. (JUN).

(2016). Chlorella sorokiniana extract improves short-term memory in rats . Molecules. 21. (10).

(2015). "natural" relief of pregnancy-related symptoms and neonatal outcomes: Above all do no harm . Journal of Ethnopharmacology. 174. p. 396-402.

(2015). Effects of anabolic-androgens on brain reward function . Frontiers in Neuroscience. 9. (AUG).

(2014). Modulatory activity of soluble beta amyloid on HPA axis function in rats . Current Pharmaceutical Design. 20. (15). p. 2539-2546.

(2014). Memantine prevents memory consolidation failure induced by soluble beta amyloid in rats . Frontiers in Behavioral Neuroscience. 8.

(2013). Brain nerve growth factor unbalance induced by anabolic androgenic steroids in rats . Medicine and Science in Sports and Exercise. 45. (1). p. 29-35.

(2013). Carvacrol: From ancient flavoring to neuromodulatory agent . Molecules. 18. (6). p. 6161-6172.

(2013). Neuroendocrine profile in a rat model of psychosocial stress: Relation to oxidative stress . Antioxidants and Redox Signaling. 18. (12). p. 1385-1399.

(2012). Neurochemical differences in two rat strains exposed to social isolation rearing . Acta Neuropsychiatrica. 24. (5). p. 286-295.

(2012). The NOP receptor involvement in both withdrawal- and CCk-8-induced contracture responses of guinea pig isolated ileum after acute activation of κ-opioid receptor . Peptides. 38. (2). p. 418-426.

(2012). Neurochemical consequence of steroid abuse: Stanozolol-induced monoaminergic changes . Steroids. 77. (3). p. 269-275.

(2012). Biphasic regulation of the acute μ-withdrawal and CCk-8 contracture responses by the ORL-1 system in guinea pig ileum . Pharmacological Research. 65. (1). p. 100-110.

(2011). Estrous cycle affects the neurochemical and neurobehavioral profile of carvacrol-treated female rats . Toxicology and Applied Pharmacology. 255. (2). p. 169-175.

(2010). The NADPH oxidase NOX2 controls glutamate release: A novel mechanism involved in psychosis-like ketamine responses . Journal of Neuroscience. 30. (34). p. 11317-11325.

(2010). Acute withdrawal induced by adenosine A<inf>1</inf>-receptor activation in isolated Guinea-pig ileum: Role of opioid receptors and effect of cholecystokinin . Journal of Pharmacy and Pharmacology. 62. (5). p. 622-632.

(2008). Counteracting effect of papaverine on morphine inhibition of gastrointestinal transit in mice . Neurogastroenterology and Motility. 20. (8). p. 958-965.

(2005). Inhibitory control of the acute mu-withdrawal response by indirectly activated adenosine A1 and kappa-opioid systems in the guinea-pig ileum; reversal by cholecystokinin . NeuroToxicology. 26. (5). p. 829-839.

(2005). Involvement of the cannabinoid CB<inf>1</inf> receptor in the opioid inhibition of the response to cholecystokinin and acute withdrawal response . NeuroToxicology. 26. (5). p. 819-827.

Bolle, P., Mastrangelo, S., Tucci, P., Evandri, M.G.(2004). Clastogenicity of Atrazine Assessed with the Allium cepa Test . Environmental and Molecular Mutagenesis. 43. (2). p. 137-141.

(2004). The effects of nitric oxide on striatal serotoninergic transmission involve multiple targets: An in vivo microdialysis study in the awake rat . Brain Research. 1008. (2). p. 293-298.

(2003). Biologic activity of the tachykinins on lamb and sheep gallbladder . Peptides. 24. (4). p. 543-551.

(2003). Role of the cholinergic system and of apamin-sensitive Ca ²⁺-activated K⁺ channels on rabbit jejunum spontaneous activity and on the inhibitory effects of adrenoceptor agonists . Autonomic and Autacoid Pharmacology. 23. (2). p. 105-115.

(2003). Synthesis of 1-methyl-5-(pyrazol-3- and -5-yl- and 1,2,4-triazol-3- and 5-yl)-1,2,3,6-tetrahydropyridine derivatives and their evaluation as muscarinic receptor ligands . Archiv der Pharmazie. 336. (3). p. 143-154.

(2002). Tachykinin-independent activity of capsaicin on in-vitro lamb detrusor . Journal of Pharmacy and Pharmacology. 54. (8). p. 1111-1115.

Tucci, P., Bartocci, C., Bolle, P.(2002). Cyclo-oxygenase- and capsaicin-sensitive afferent fibres affect beta-adrenoceptor-evoked response in the rat urinary bladder . Pharmacology. 64. (2). p. 57-62.

(2001). Interactions between Δ-9THC and capsaicin on isolated lamb bladder detrusor . Farmaco. 56. (5-7). p. 349-351.

(2001). Effects of natural tachykinins on ovine lower urinary tract smooth muscle . Journal of Autonomic Pharmacology. 21. (2). p. 79-84.

(2000). Toxicological evaluation of commercial mineral water bottled in polyethylene terephthalate: A cytogenetic approach with Allium cepa . Food Additives and Contaminants. 17. (12). p. 1037-1045.

(2000). Effects of natural tachykinins on porcine lower urinary tract smooth muscle . Journal of Autonomic Pharmacology. 20. (3). p. 157-161.

(1999). Response to isoprenaline of rabbit detrusor muscle following exposure to 5, 8, 11, 14 tetraynoic acid. Role of prostanoids on beta-adrenergic-evoked response . Journal of Autonomic Pharmacology. 19. (3). p. 161-165.

(1998). Response of rabbit detrusor muscle to total extract and major alkaloids of Hydrastis canadensis. Phytotherapy Research. 12. (SUPPL. 1).

(1998). Response to isoproterenol of rabbit detrusor strips following exposure to NSAIDs . Pharmacological Research. 37. (5). p. 395-401.

(1996). Facilitating effect of harmaline on phenylephrine contraction in rabbit urethra . Phytotherapy Research. 10. (SUPPL. 1).