Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 50 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Paula C.

Germany

USD 50 /hr

Neuroscientist | Writer | In Vivo Research & Microscopy Expert

Profile Summary

Neuroscientist with a strong background in brain development, gene regulation, epigenetics, and brain evolution. During my PhD, I investigated the role of extracellular factors in regulating cell proliferation in the developing brain, with a focus on how epigenetic modifications and enhancers control their gene expression. My research also explored evolutionary differences in gene regulation between species. Prior to my PhD, I worked for four years in neuroscience, specializing in neurodegenerative diseases such as Alzheimer’s and frontotemporal dementia, as well as memory decline during aging. Published in high-impact journals, I have a strong track record of designing and executing complex research projects and effectively communicating scientific findings.

Subject Matter Expertise

• ★ Molecular Cloning
• ★ Molecular Neuroscience
• ★ Technical & Scientific Writing
• ☆ Evolutionary Biology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Genetics
• ☆ Chromatin
• ☆ Epigenetics
• ☆ PCR
• ☆ Microinjection
• ☆ Plasmid DNA
• ☆ ChIP-Seq
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Gene Regulation
• ☆ Stem Cell Research
• ☆ Neuroscience
• ☆ Neurochemistry
• ☆ Neurophysiology
• ☆ Behavioral Neuroscience
• ☆ Cognitive Neuroscience
• ☆ Neuroanatomy
• ☆ Developmental Neuroscience
• ☆ Microscopy
• ☆ Cryosectioning
• ☆ Light Microscopy
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Manuscript & Journal Article Writing

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Creative Writing, General Proofreading & Editing, Translation

Research Fact Checking, Gap Analysis, Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Image Analysis

Work Experience

PhD candidate

Laboratory of Gene Regulatory Mechanisms of Neocortex Evolution - Center for Regenerative Therapies

January 2020 - June 2024

Laboratory Technician

Laboratory of Neuropharmacology - Center of Biomedical Research, Universidad Autónoma de Chile. Sant

January 2019 - December 2019

Master student

Laboratory of Neuroepigenetics - Institute of Biomedical Research, Universidad Andrés Bello. Santiag

March 2016 - December 2018

Education

Doctor of Philosophy (PhD)

Technische Universität Dresden

January 2020 - January 2025

Master of Science (MSc) in Biochemistry

Universidad Andrés Bello

March 2016 - January 2019

Bachelor of Science (BSc) in Biochemistry

Universidad Andrés Bello

March 2012 - December 2015

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Annika Kolodziejczyk, Janine Hoffmann, Paula Cubillos, Mareike Albert (2024). Electroporation of Sliced Human Cortical Organoids for Studies of Gene Function . Journal of Visualized Experiments.

Paula Cubillos, Nora Ditzer, Annika Kolodziejczyk, Gustav Schwenk, Janine Hoffmann, Theresa M Schütze, Razvan Petru Derihaci, Cahit Birdir, Johannes Köllner, Andreas Petzold, et al. (2024). The growth factor EPIREGULIN promotes basal progenitor cell proliferation in the developing neocortex . The EMBO Journal.

Nur Jury, Sebastian Abarzua, Ivan Diaz, Miguel V. Guerra, Estibaliz Ampuero, Paula Cubillos, Pablo Martinez, Andrea Herrera-Soto, Cristian Arredondo, Fabiola Rojas, et al. (2020). Widespread loss of the silencing epigenetic mark H3K9me3 in astrocytes and neurons along with hippocampal-dependent cognitive impairment in C9orf72 BAC transgenic mice . Clinical Epigenetics.

Fernando J Bustos, Estibaliz Ampuero, Nur Jury, Rodrigo Aguilar, Fahimeh Falahi, Jorge Toledo, Juan Ahumada, Jaclyn Lata, Paula Cubillos, Berta Henríquez, et al. (2017). Epigenetic editing of the Dlg4/PSD95 gene improves cognition in aged and Alzheimer’s disease mice . Brain.