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★★★★★
☆☆☆☆☆
USD 110 /hr
Hire Dr. Noortje Eleonora F.
Netherlands
USD 110 /hr

Medical Doctor (PhD) | AI & Predictive Modeling for Biomedical Research | Data Science Expert

Profile Summary
Subject Matter Expertise
Services
Writing Medical Writing, Technical Writing
Research Scientific and Technical Research
Consulting Healthcare Consulting, Scientific and Technical Consulting
Data & AI Predictive Modeling, Statistical Analysis, Image Processing, Image Analysis, Algorithm Design-Non ML, Algorithm Design-ML, Data Visualization, Big Data Analytics, Text Mining & Analytics, Data Mining, Data Cleaning, Data Processing, Data Insights
Work Experience

GASTROENTEROLOGIST

UMCG

November 2017 - Present

Principle Investigator

UMCG

November 2017 - Present

Lecturer for the study of Medicine

University of Groningen

October 2016 - Present

Research fellow

Broad Institute, Harvard Medical School

October 2016 - October 2017

Education

Medical doctor

University of Groningen

September 2002 - September 2008

Certifications

  • PhD in human genetics

    University of Groningen

    March 2008 - Present

Publications
JOURNAL ARTICLE
Naomi Karmi, Shiqiang Sun, Eleonora A M Festen, Arnau Vich Vila, Ranko Gacesa, Rinse K Weersma (2024). Gut microbial metabolism of 5-aminosalicylic acid in inflammatory bowel disease . Gut.
Zainab M A Al Radi, Femke M Prins, Valerie Collij, Arnau Vich Vila, Eleonora A M Festen, Gerard Dijkstra, Rinse K Weersma, Marjolein A Y Klaassen, Ranko Gacesa (2024). Exploring the Predictive Value of Gut Microbiome Signatures for Therapy Intensification in Patients With Inflammatory Bowel Disease: A 10-Year Follow-up Study . Inflammatory Bowel Diseases.
Bourgonje AR, Andreu-Sánchez S, Vogl T, Hu S, Vich Vila A, Gacesa R, Leviatan S, Kurilshikov A, Klompus S, Kalka IN, et al.(2023). Phage-display immunoprecipitation sequencing of the antibody epitope repertoire in inflammatory bowel disease reveals distinct antibody signatures . Immunity.
Loveikyte R, Bourgonje AR, van der Reijden JJ, Bulthuis MLC, Hawinkels LJAC, Visschedijk MC, Festen EAM, van Dullemen HM, Weersma RK, van Goor H, et al.(2023). Hepcidin and Iron Status in Patients With Inflammatory Bowel Disease Undergoing Induction Therapy With Vedolizumab or Infliximab . Inflammatory bowel diseases.
Arno R. Bourgonje, Marta S. Alexdottir, Antonius T. Otten, Roberta Loveikyte, Anne‐Christine Bay‐Jensen, Martin Pehrsson, Hendrik M. van Dullemen, Marijn C. Visschedijk, Eleonora A. M. Festen, Rinse K. Weersma, et al. (2022). Serological biomarkers of type I, III and IV collagen turnover are associated with the presence and future progression of stricturing and penetrating Crohnʼs disease . Alimentary Pharmacology & Therapeutics.
Swarte JC, Li Y, Hu S, Björk JR, Gacesa R, Vich Vila A, Douwes RM, Collij V, Kurilshikov A, Post A, et al.(2022). Gut microbiome dysbiosis is associated with increased mortality after solid organ transplantation . Science translational medicine.
Bourgonje AR, Wichers SJ, Hu S, van Dullemen HM, Visschedijk MC, Faber KN, Festen EAM, Dijkstra G, Samsom JN, Weersma RK, et al.(2022). Proteomic analyses do not reveal subclinical inflammation in fatigued patients with clinically quiescent inflammatory bowel disease . Scientific reports.
Alexdottir MS, Bourgonje AR, Karsdal MA, Pehrsson M, Loveikyte R, van Dullemen HM, Visschedijk MC, Festen EAM, Weersma RK, Faber KN, et al.(2022). Serological Biomarkers of Extracellular Matrix Turnover and Neutrophil Activity Are Associated with Long-Term Use of Vedolizumab in Patients with Crohn's Disease . International journal of molecular sciences.
Alexdottir MS, Bourgonje AR, Karsdal MA, Pehrsson M, Loveikyte R, van Dullemen HM, Visschedijk MC, Festen EAM, Weersma RK, Faber KN, et al.(2022). Serological Biomarkers of Intestinal Collagen Turnover Identify Early Response to Infliximab Therapy in Patients With Crohn's Disease . Frontiers in medicine.
Otten AT, Bourgonje AR, Horinga PP, van der Meulen HH, Festen EAM, van Dullemen HM, Weersma RK, van Leer-Buter CC, Dijkstra G, Visschedijk MC(2022). Use of Tumor Necrosis Factor-α Antagonists Is Associated With Attenuated IgG Antibody Response Against SARS-CoV-2 in Vaccinated Patients With Inflammatory Bowel Disease . Frontiers in immunology.
Uniken Venema WTC, Ramírez-Sánchez AD, Bigaeva E, Withoff S, Jonkers I, McIntyre RE, Ghouraba M, Raine T, Weersma RK, Franke L, et al.(2022). Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels . Scientific reports.
Bourgonje AR, Bolte LA, Vranckx LLC, Spekhorst LM, Gacesa R, Hu S, van Dullemen HM, Visschedijk MC, Festen EAM, Samsom JN, et al.(2022). Long-Term Dietary Patterns Are Reflected in the Plasma Inflammatory Proteome of Patients with Inflammatory Bowel Disease . Nutrients.
Bourgonje AR, Hu S, Spekhorst LM, Zhernakova DV, Vich Vila A, Li Y, Voskuil MD, van Berkel LA, Bley Folly B, Charrout M, et al.(2022). The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease . Journal of Crohn's & colitis.
Li Y, Nieuwenhuis LM, Keating BJ, Festen EAM, de Meijer VE(2021). The Impact of Donor and Recipient Genetic Variation on Outcomes After Solid Organ Transplantation: A Scoping Review and Future Perspectives . Transplantation.
Karmi N, Bangma A, Spekhorst LM, van Dullemen HM, Visschedijk MC, Dijkstra G, Weersma RK, Voskuil MD, Festen EAM(2021). Polygenetic risk scores do not add predictive power to clinical models for response to anti-TNFα therapy in inflammatory bowel disease . PloS one.
van der Sloot KWJ, Voskuil MD, Blokzijl T, Dinkla A, Ravesloot L, Visschedijk MC, van Dullemen HM, Festen EAM, Alizadeh BZ, van Leer-Buter C, et al.(2021). Isotype-specific Antibody Responses to Mycobacterium avium paratuberculosis Antigens Are Associated With the Use of Biologic Therapy in Inflammatory Bowel Disease . Journal of Crohn's & colitis.
Peters V, Spooren CEGM, Pierik MJ, Weersma RK, van Dullemen HM, Festen EAM, Visschedijk MC, Masclee AAM, Hendrix EMB, Almeida RJ, et al.(2021). Dietary Intake Pattern is Associated with Occurrence of Flares in IBD Patients . Journal of Crohn's & colitis.
Voskuil MD, Spekhorst LM, van der Sloot KWJ, Jansen BH, Dijkstra G, van der Woude CJ, Hoentjen F, Pierik MJ, van der Meulen AE, de Boer NKH, et al.(2021). Genetic Risk Scores Identify Genetic Aetiology of Inflammatory Bowel Disease Phenotypes . Journal of Crohn's & colitis.
Festen EAM, Weersma RK(2021). Large-scale genetic analyses in an understudied disease: haemorrhoidal disease . Gut.
Bourgonje AR, van Linschoten RCA, West RL, van Dijk MA, van Leer-Buter CC, Kats-Ugurlu G, Pierik MJ, Festen EAM, Weersma RK, Dijkstra G(2021). Treatment of severe acute ulcerative colitis in SARS-CoV-2 infected patients: report of three cases and discussion of treatment options . Therapeutic advances in gastroenterology.
Kimberley W J van der Sloot, Paul Geertsema, Hanneke C Rijkmans, Michiel D Voskuil, Hendrik M van Dullemen, Marijn C Visschedijk, Eleonora A M Festen, Rinse K Weersma, Behrooz Z Alizadeh, Gerard Dijkstra (2021). Environmental factors associated with biological use and surgery in inflammatory bowel disease . Journal of Gastroenterology and Hepatology.
Haisma SM, Weersma RK, Joosse ME, de Koning BAE, de Meij T, Koot BGP, Wolters V, Norbruis O, Daly MJ, Stevens C, et al.(2021). Exome sequencing in patient-parent trios suggests new candidate genes for early-onset primary sclerosing cholangitis . Liver international : official journal of the International Association for the Study of the Liver.
Hu S, Uniken Venema WT, Westra HJ, Vich Vila A, Barbieri R, Voskuil MD, Blokzijl T, Jansen BH, Li Y, Daly MJ, et al.(2021). Inflammation status modulates the effect of host genetic variation on intestinal gene expression in inflammatory bowel disease . Nature communications.
Li Y, Nieuwenhuis LM, Voskuil MD, Gacesa R, Hu S, Jansen BH, Venema WTU, Hepkema BG, Blokzijl H, Verkade HJ, et al.(2021). Donor genetic variants as risk factors for thrombosis after liver transplantation: A genome-wide association study . American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
Gacesa R, Vich Vila A, Collij V, Mujagic Z, Kurilshikov A, Voskuil MD, Festen EAM, Wijmenga C, Jonkers DMAE, Dijkstra G, et al.(2021). A combination of fecal calprotectin and human beta-defensin 2 facilitates diagnosis and monitoring of inflammatory bowel disease . Gut microbes.
van der Sloot KWJ, Tiems JL, Visschedijk MC, Festen EAM, van Dullemen HM, Weersma RK, Kats-Ugurlu G, Dijkstra G(2021). Cigarette Smoke Increases Risk for Colorectal Neoplasia in Inflammatory Bowel Disease . Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
(2020). <b>UEG</b> Week 2020 Poster Presentations . United European gastroenterology journal.
van der Laan JJH, van der Waaij AM, Gabri&#235;ls RY, Festen EAM, Dijkstra G, Nagengast WB(2020). Endoscopic imaging in inflammatory bowel disease: current developments and emerging strategies . Expert review of gastroenterology & hepatology.
(2020). UEG Week 2020 Oral Presentations . United European gastroenterology journal.
Bigaeva E, Uniken Venema WTC, Weersma RK, Festen EAM(2020). Understanding human gut diseases at single-cell resolution . Human molecular genetics.
Hu S, Vich Vila A, Gacesa R, Collij V, Stevens C, Fu JM, Wong I, Talkowski ME, Rivas MA, Imhann F, et al.(2020). Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD . Gut.
Li Y, Nieuwenhuis LM, Werner MJM, Voskuil MD, Gacesa R, Blokzijl H, Lisman T, Weersma RK, Porte RJ, Festen EAM, et al.(2020). Donor tobacco smoking is associated with postoperative thrombosis after primary liver transplantation . Journal of thrombosis and haemostasis : JTH.
van der Sloot KWJ, Voskuil MD, Visschedijk MC, Festen EAM, van Dullemen HM, Weersma RK, Alizadeh BZ, van Leer-Buter C, Dijkstra G(2020). Latent cytomegalovirus infection does not influence long-term disease outcomes in inflammatory bowel disease, but is associated with later onset of disease . Scandinavian journal of gastroenterology.
von Martels JZH, Bourgonje AR, Klaassen MAY, Alkhalifah HAA, Sadaghian Sadabad M, Vich Vila A, Gacesa R, Gabri&#235;ls RY, Steinert RE, Jansen BH, et al.(2020). Riboflavin Supplementation in Patients with Crohn's Disease [the RISE-UP study] . Journal of Crohn's & colitis.
Amber Bangma, Michiel D. Voskuil, Werna T. C. Uniken Venema, Harm Brugge, Shixian Hu, Pauline Lanting, Lude Franke, Gerard Dijkstra, Eleonora A. M. Festen, Rinse K. Weersma(2020). Predicted efficacy of a pharmacogenetic passport for inflammatory bowel disease . Alimentary Pharmacology & Therapeutics. 51. (11). p. 1105--1115. Wiley
Bourgonje AR, von Martels JZH, Gabri&#235;ls RY, Blokzijl T, Buist-Homan M, Heegsma J, Jansen BH, van Dullemen HM, Festen EAM, Ter Steege RWF, et al.(2019). A Combined Set of Four Serum Inflammatory Biomarkers Reliably Predicts Endoscopic Disease Activity in Inflammatory Bowel Disease . Frontiers in medicine.
Klaassen MAY, Imhann F, Collij V, Fu J, Wijmenga C, Zhernakova A, Dijkstra G, Festen EAM, Gacesa R, Vich Vila A, et al.(2019). Anti-inflammatory Gut Microbial Pathways Are Decreased During Crohn's Disease Exacerbations . Journal of Crohn's & colitis.
Voskuil MD, Bangma A, Weersma RK, Festen EAM(2019). Predicting (side) effects for patients with inflammatory bowel disease: The promise of pharmacogenetics . World journal of gastroenterology.
Uniken Venema WT, Voskuil MD, Festen EA(2019). Reply . Gastroenterology.
Imhann F, Van der Velde KJ, Barbieri R, Alberts R, Voskuil MD, Vila AV, Collij V, Spekhorst LM, Van der Sloot KWJ, Peters V, et al.(2019). Correction to: The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1 . BMC gastroenterology.
van der Velde KJ, Imhann F, Charbon B, Pang C, van Enckevort D, Slofstra M, Barbieri R, Alberts R, Hendriksen D, Kelpin F, et al.(2019). MOLGENIS research: advanced bioinformatics data software for non-bioinformaticians . Bioinformatics (Oxford, England).
Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, et al.(2019). Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease . JAMA.
Collij V, Imhann F, Vich Vila A, Fu J, Dijkstra G, Festen EAM, Voskuil MD, Daly MJ, Xavier RJ, Wijmenga C, et al.(2019). SLC39A8 missense variant is associated with Crohn's disease but does not have a major impact on gut microbiome composition in healthy subjects . PloS one.
Imhann F, Van der Velde KJ, Barbieri R, Alberts R, Voskuil MD, Vich Vila A, Collij V, Spekhorst LM, Van der Sloot KWJ, Peters V, et al.(2019). The 1000IBD project: multi-omics data of 1000 inflammatory bowel disease patients; data release 1 . BMC gastroenterology.
Vich Vila A, Imhann F, Collij V, Jankipersadsing SA, Gurry T, Mujagic Z, Kurilshikov A, Bonder MJ, Jiang X, Tigchelaar EF, et al.(2018). Gut microbiota composition and functional changes in inflammatory bowel disease and irritable bowel syndrome . Science translational medicine.
Buurman DJ, Blokzijl T, Festen EAM, Pham BT, Faber KN, Brouwer E, Dijkstra G(2018). Quantitative comparison of the neutralizing capacity, immunogenicity and cross-reactivity of anti-TNF-α biologicals and an Infliximab-biosimilar . PloS one.
Uniken Venema WT, Voskuil MD, Vila AV, van der Vries G, Jansen BH, Jabri B, Faber KN, Dijkstra G, Xavier RJ, Wijmenga C, et al.(2018). Single-Cell RNA Sequencing of Blood and Ileal T Cells From Patients With Crohn's Disease Reveals Tissue-Specific Characteristics and Drug Targets . Gastroenterology.
Weersma RK, Xavier RJ, IBD Multi Omics Consortium, Vermeire S, Barrett JC(2018). Multiomics Analyses to Deliver the Most Effective Treatment to Every Patient With Inflammatory Bowel Disease . Gastroenterology.
Momozawa Y, Dmitrieva J, Th&#233;&#226;tre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, et al.(2018). IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes . Nature communications.
Severs M, Spekhorst LM, Mangen MJ, Dijkstra G, L&#246;wenberg M, Hoentjen F, van der Meulen-de Jong AE, Pierik M, Ponsioen CY, Bouma G, et al.(2018). Sex-Related Differences in Patients With Inflammatory Bowel Disease: Results of 2 Prospective Cohort Studies . Inflammatory bowel diseases.
Visschedijk MC, Spekhorst LM, Cheng SC, van Loo ES, Jansen BHD, Blokzijl T, Kil H, de Jong DJ, Pierik M, Maljaars JPWJ, et al.(2018). Genomic and Expression Analyses Identify a Disease-Modifying Variant for Fibrostenotic Crohn's Disease . Journal of Crohn's & colitis.
Spekhorst LM, Oldenburg B, van Bodegraven AA, de Jong DJ, Imhann F, van der Meulen-de Jong AE, Pierik MJ, van der Woude JC, Dijkstra G, D&#39;Haens G, et al.(2017). Prevalence of- and risk factors for work disability in Dutch patients with inflammatory bowel disease . World journal of gastroenterology.
Spekhorst LM, Severs M, de Boer NKH, Festen EAM, Fidder HH, Hoentjen F, Imhann F, de Jong DJ, van der Meulen-de Jong AE, Pierik MJ, et al.(2017). The Impact of Ethnicity and Country of Birth on Inflammatory Bowel Disease Phenotype: a Prospective Cohort Study . Journal of Crohn's & colitis.
Spekhorst LM, Imhann F, Festen EAM, van Bodegraven AA, de Boer NKH, Bouma G, Fidder HH, d&#39;Haens G, Hoentjen F, Hommes DW, et al.(2017). Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease . BMJ open.
Alberts R, de Vries EMG, Goode EC, Jiang X, Sampaziotis F, Rombouts K, B&#246;ttcher K, Folseraas T, Weism&#252;ller TJ, Mason AL, et al.(2017). Genetic association analysis identifies variants associated with disease progression in primary sclerosing cholangitis . Gut.
Uniken Venema WT, Voskuil MD, Dijkstra G, Weersma RK, Festen EA(2016). The genetic background of inflammatory bowel disease: from correlation to causality . The Journal of pathology.
Imhann F, Vich Vila A, Bonder MJ, Fu J, Gevers D, Visschedijk MC, Spekhorst LM, Alberts R, Franke L, van Dullemen HM, et al.(2016). Interplay of host genetics and gut microbiota underlying the onset and clinical presentation of inflammatory bowel disease . Gut.
Collij, Valerie, Festen, Eleonora A. M., Alberts, Rudi, Weersma, Rinse K. (2016). Drug Repositioning in Inflammatory Bowel Disease Based on Genetic Information . Inflammatory Bowel Diseases.
Spekhorst, L. M., Imhann, F., Festen, E. A. M., van Bodegraven, A. A., de Boer, N. K. H., Bouma, G., Fidder, H. H., D&#39;Haens, G. R. A. M., Hoentjen, F., Hommes, D. W., et al. (2016). First results and information model from the Parelsnoer Institute IBD biobank: a nationwide standardised inflammatory bowel disease collection by all university medical centres in the Netherlands . Journal of Crohn's and Colitis.
Visschedijk, M. C., Spekhorst, L. M., Dijkstra, G., van Loo, E. S., de Jong, D. J., van der Meulen-de Jong, A. E., Verspaget, H. W., Ponsioen, C. Y., Nieuwenhuijs, V. B., Oldenburg, B., et al. (2016). Identification of a genetic risk variant in the WWOX gene associated with recurrent fibrostenotic Crohn's disease . Journal of Crohn's and Colitis.
Imhann, Floris, Vila, Arnau Vich, Bonder, Marc Jan, Gevers, Dirk, Fu, Jingyuan, Visschedijk, Marijn C., Spekhorst, Lieke M., Franke, Lude, van Dullemen, Hendrik, Ter Steege, Rinze, et al. (2016). Gene-Microbiome Interactions Underlying the Onset and the Clinical Phenotypes of Inflammatory Bowel Disease . Gastroenterology.
Alberts, R., de Vries, E. M., Alexander, G., Alvaro, D., Bergquist, A., Beuers, U., Bjornsson, E., Boberg, K. M., Bowlus, C. L., Chapman, R. W., et al. (2016). Genotype-phenotype analysis across 130 422 genetic variants identifies RSPO3 as the first genome-wide significant modifier gene in primary sclerosing cholangitis . Journal of Crohn's and Colitis.
Cleynen I, Boucher G, Jostins L, Schumm LP, Zeissig S, Ahmad T, Andersen V, Andrews JM, Annese V, Brand S, et al.(2015). Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study . Lancet (London, England).
Liu JZ, van Sommeren S, Huang H, Ng SC, Alberts R, Takahashi A, Ripke S, Lee JC, Jostins L, Shah T, et al.(2015). Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations . Nature genetics.
Goyette P, Boucher G, Mallon D, Ellinghaus E, Jostins L, Huang H, Ripke S, Gusareva ES, Annese V, Hauser SL, et al.(2015). High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis . Nature genetics.
Spekhorst, Lieke M., Visschedijk, Marijn C., Weersma, Rinse K., Festen, Eleonora Anna (2015). Down the line from genome-wide association studies in inflammatory bowel disease: the resulting clinical benefits and the outlook for the future . Expert Review of Clinical Immunology.
Spekhorst, Lieke M., Visschedijk, Marijn C., Alberts, Rudi, Festen, Eleonora A., van der Wouden, Egbert-Jan, Dijkstra, Gerard, Weersma, Rinse K. (2014). Performance of the Montreal classification for inflammatory bowel diseases . World Journal of Gastroenterology.
Festen, E. A. M., Weersma, R. K. (2014). How will insights from genetics translate to clinical practice in inflammatory bowel disease? . Best Practice & Research: Clinical Gastroenterology.
Fehrmann, Rudolf S. N., Jansen, Ritsert C., Veldink, Jan H., Westra, Harm-Jan, Arends, Danny, Bonder, Marc Jan, Fu, Jingyuan, Deelen, Patrick, Groen, Harry J. M., Smolonska, Asia, et al. (2011). <i>Trans</i>-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA . PLOS Genetics.
Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Raychaudhuri, Soumya, Festen, Eleanora, Franke, Lude, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, Gupta, Namrata, et al. (2011). META-ANALYSIS OF GENOME-WIDE ASSOCIATION STUDIES IN CELIAC DISEASE AND RHEUMATOID ARTHRITIS IDENTIFIES FOURTEEN NON-HLA SHARED LOCI . Annals of the Rheumatic Diseases.
Festen, Eleonora A. M., Goyette, Philippe, Green, Todd, Boucher, Gabrielle, Beauchamp, Claudine, Trynka, Gosia, Dubois, Patrick C., Lagace, Caroline, Stokkers, Pieter C. F., Hommes, Daan W., et al. (2011). A Meta-Analysis of Genome-Wide Association Scans Identifies IL18RAP, PTPN2, TAGAP, and PUS10 As Shared Risk Loci for Crohn's Disease and Celiac Disease . PLOS Genetics.
Janse, M., Weersma, R. K., Sudan, D. L., Festen, E. A. M., Wijmenga, C., Dijkstra, G., Mercer, D. (2011). Association of Crohn's disease-associated NOD2 variants with intestinal failure requiring small bowel transplantation and clinical outcomes . Gut.
van Sommeren, Suzanne, Visschedijk, Marijn C., Festen, Eleonora A. M., de Jong, Dirk J., Ponsioen, Cyriel Y., Wijmenga, Cisca, Weersma, Rinse K. (2011). HNF4 alpha and CDH1 Are Associated with Ulcerative Colitis in a Dutch Cohort . Inflammatory Bowel Diseases.
Fu, Jingyuan, Festen, Eleonora A. M., Wijmenga, Cisca (2011). Multi-ethnic studies in complex traits . Human Molecular Genetics.
Guido H. Dolmans, Paul M. Werker, Hans C. Hennies, Dominic Furniss, Eleonora A. Festen, Lude Franke, Kerstin Becker, Pieter van der Vlies, Bruce H. Wolffenbuttel, Sigrid Tinschert, et al. (2011). Wnt Signaling and Dupuytren's Disease . New England Journal of Medicine.
Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Raychaudhuri, Soumya, Festen, Eleanora A., Franke, Lude, Westra, Harm-Jan, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, et al. (2011). Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci . PLOS Genetics.
Weersma, Rinse K., Crusius, J. Bart A., Roberts, Rebecca L., Koeleman, Bobby P. C., Palomino-Morales, Rogelio, Wolfkamp, Simone, Hollis-Moffatt, Jade E., Festen, Eleonora A. M., Meisneris, Sander, Heijmans, Roel, et al. (2010). Association of FcgR2a, but Not FcgR3a, with Inflammatory Bowel Diseases Across Three Caucasian Populations . Inflammatory Bowel Diseases.
Festen, Eleonora A. M., Stokkers, Pieter C. F., van Diemen, Cleo C., van Bodegraven, Adriaan A., Boezen, H. Marieke, Crusius, Bart J. A., Hommes, Daniel W., van der Woude, Janneke C., Balschun, Tobias, Verspaget, Hein W., et al. (2010). Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk . The American Journal of Gastroenterology.
Franke, Andre, McGovern, Dermot P. B., Barrett, Jeffrey C., Wang, Kai, Radford-Smith, Graham L., Ahmad, Tariq, Lees, Charlie W., Balschun, Tobias, Lee, James, Roberts, Rebecca, et al. (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci . Nature Genetics.
Fransen, Karin, Visschedijk, Marijn C., van Sommeren, Suzanne, Fu, Jinyuan Y., Franke, Lude, Festen, Eleonora A. M., Stokkers, Pieter C. F., van Bodegraven, Adriaan A., Crusius, J. Bart A., Hommes, Daniel W., et al. (2010). Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn's disease . Human Molecular Genetics.
Festen, Eleonora A. M., Stokkers, Pieter C. F., van Diemen, Cleo C., van Bodegraven, Adriaan A., Boezen, H. Marieke, Crusius, Bart J. A., Hommes, Daniel W., van der Woude, C. J., Balschun, Tobias, Verspaget, Hein W., et al. (2010). Genetic Analysis in A Dutch Study Sample Identifies More Ulcerative Colitis Susceptibility Loci and Shows Their Additive Role in Disease Risk (vol 105, pg 395, 2010) . The American Journal of Gastroenterology.
Festen EA, Szperl AM, Weersma RK, Wijmenga C, Wapenaar MC(2009). Inflammatory bowel disease and celiac disease: overlaps in the pathology and genetics, and their potential drug targets . Endocrine, metabolic & immune disorders drug targets.
Visschedijk MC, Festen EA, Wijmenga C, Weersma RK(2009). [The genetic basis of inflammatory bowel disease unravelled by genetic association studies] . Nederlands tijdschrift voor geneeskunde.
de Vries, Hilbert S., Plantinga, Theo S., van Krieken, J. Han, Stienstra, Rinke, van Bodegraven, Ad A., Festen, Eleonora A. M., Weersma, Rinse K., Crusius, J. Bart A., Linskens, Ronald K., Joosten, Leo A. B., et al. (2009). Genetic Association Analysis of the Functional c.714T&gt;G Polymorphism and Mucosal Expression of Dectin-1 in Inflammatory Bowel Disease . Plos One.
Festen, Eleonora A., Goyette, Philippe, Scott, Regan, Annese, Vito, Zhemakova, Alexandra, Brant, Steven R., Cho, Judy H., Silverberg, Mark S., Taylor, Kent D., De Jong, Dirk J., et al. (2009). Genetic Variants in the Region Harbouring IL2/IL21 Associated to Ulcerative Colitis . Gastroenterology.
Festen, Eleonora A., Stokkers, Pieter, Wapenaar, Martin C., van Diemen, Cleo C., van Bodegraven, Ad A., Bruinenberg, Marcel, Boezen, Hendrika M., Crusius, Bart, Hommes, Daniel, van der Woude, Christien J., et al. (2009). Genetic and Mucosal Expression Analysis Shows Important Roles for JAK2 and MST1 in the Pathogenesis of Ulcerative Colitis and Identifies More Susceptibility Loci . Gastroenterology.
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