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USD 22 /hr
Hire Dr. Nihal E.
Egypt
USD 22 /hr
Pharmaceutical Researcher and Drug Delivery Expert with 15+ experience in formulation and drug maunfacturing
Profile Summary
Subject Matter Expertise
Services
Writing
Clinical Trial Documentation,
Medical Writing,
Technical Writing
Research
Meta-Research
Consulting
Scientific and Technical Consulting
Data & AI
Predictive Modeling,
Statistical Analysis,
Algorithm Design-ML,
Data Visualization,
Data Mining,
Data Cleaning,
Data Processing,
Data Insights
Product Development
Formulation,
Recipe Development,
Stability/Shelf Life Testing,
Product Evaluation,
Product Validation,
Manufacturing,
Quality Assurance & Control (QA/QC)
Work Experience
Associate Professor
October University for Modern Sciences and Arts Faculty of Pharmacy
- Present 
Trainer and Instructional Designer
MSA University
February 2022 - Present
Education
PhD
Cairo University
February 2015 - February 2019
Master in Business Adminstration
Arab Academy for Sciences, Arts and Maritime Transport
May 2011 - October 2013
Certifications
Publications
JOURNAL ARTICLE
Nihal Elsayyad, Ahmed M. Agiba, Rabab A. El-Gazar, Mohamed A. Mekkawy, Hala N. ElShagea, Patricia Segura-Medina, Raghda Rabe Hamed (2025). Advancing Photodynamic Cancer Therapy with Smart Light-Responsive Lipid and Polymeric Nanocarriers: Evidence from a Meta-Analysis of Efficacy and Pharmacokinetics . Pharmaceuticals.
Nihal Elsayyad, Ahmed M. Agiba, Rabab A. El-Gazar, Mohamed A. Mekkawy, Hala N. ElShagea, Patricia Segura-Medina, Raghda Rabe Hamed (2025). Advancing Photodynamic Cancer Therapy with Smart Light-Responsive Lipid and Polymeric Nanocarriers: Evidence from a Meta-Analysis of Efficacy and Pharmacokinetics . Pharmaceuticals.
Mervat Shafik Ibrahim, Nihal Mohamed Elmahdy Elsayyad, Shereen H. Noshi (2025). Development and Evaluation of a PH-Responsive Bovine Serum Albumin-Functionalized Layered Double Hydroxide Nanocarrier for Targeted Therapy of Ovarian Cancer . Journal of Pharmaceutical Innovation.
Nihal Mohamed Elmahdy Elsayyad, Omar A. Elkady, Mohamed M. Swidan, Hassan M. Rashed, Tamer M. Sakr, Amr M. Abdelhamid, Mai A. Zaafan, Hanan M. El-Laithy (2025). Zonisamide nanodiamonds for brain targeting: A comprehensive study utilising in silico, in vitro, in vivo, and molecular investigation for successful nose-to-brain delivery for epilepsy management . Drug Delivery and Translational Research.
Eiman Abdalla Madawi, Hanan M. El-Laithy, Nihal Mohamed Elmahdy Elsayyad, Mutasem Rawas-Qalaji, Amjad Alhalaweh, Iman Saad Ahmed (2025). Development and optimization of lyophilized dry emulsion tablet for improved oral delivery of Ivermectin . Journal of Drug Delivery Science and Technology.
Nihal Mohamed Elmahdy Elsayyad, Mervat Shafik Ibrahim, Shereen H. Noshi (2025). Sustainable pH-responsive casein/hyaluronic acid layered nanoparticles for targeted delivery of metformin to colorectal cancer . Journal of Drug Delivery Science and Technology.
Elsayyad, N.M.E., Ibrahim, M.S., Noshi, S.H.(2025). Sustainable pH-responsive casein/hyaluronic acid layered nanoparticles for targeted delivery of metformin to colorectal cancer . Journal of Drug Delivery Science and Technology. 107.
Ibrahim, M.S., Elsayyad, N.M.E., Noshi, S.H.(2025). Development and Evaluation of a PH-Responsive Bovine Serum Albumin-Functionalized Layered Double Hydroxide Nanocarrier for Targeted Therapy of Ovarian Cancer . Journal of Pharmaceutical Innovation. 20. (5).
Elsayyad, N.M.E., Elkady, O.A., Swidan, M.M., Rashed, H.M., Sakr, T.M., Abdelhamid, A.M., Zaafan, M.A., El-Laithy, H.M.(2025). Zonisamide nanodiamonds for brain targeting: A comprehensive study utilising in silico, in vitro, in vivo, and molecular investigation for successful nose-to-brain delivery for epilepsy management . Drug Delivery and Translational Research.
Madawi, E.A., El-Laithy, H.M., Elmahdy Elsayyad, N.M., Rawas-Qalaji, M., Alhalaweh, A., Ahmed, I.S.(2025). Development and optimization of lyophilized dry emulsion tablet for improved oral delivery of Ivermectin . Journal of Drug Delivery Science and Technology. 108.
Nihal Elsayyad, Ahmed M. Agiba, Hala N. ElShagea, Mahmoud A. Metwalli, Amin Orash Mahmoudsalehi, Saeed Beigi-Boroujeni, Omar Lozano, Alan Aguirre-Soto, Jose Luis Arreola-Ramirez, Patricia Segura-Medina, et al. (2024). Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy . Pharmaceutics.
Nihal Elsayyad, Ahmed M. Agiba, Hala N. ElShagea, Mahmoud A. Metwalli, Amin Orash Mahmoudsalehi, Saeed Beigi-Boroujeni, Omar Lozano, Alan Aguirre-Soto, Jose Luis Arreola-Ramirez, Patricia Segura-Medina, et al. (2024). Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy . Pharmaceutics.
Agiba, A.M., Elsayyad, N., ElShagea, H.N., Metwalli, M.A., Mahmoudsalehi, A.O., Beigi-Boroujeni, S., Lozano, O., Aguirre-Soto, A., Arreola-Ramirez, J.L., Segura-Medina, P., et al.(2024). Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy . Pharmaceutics. 16. (8).
Maha M. Salama, Nora M. Aborehab, Nihal M. El Mahdy, Ahmed Zayed, Shahira M. Ezzat (2023). Nanotechnology in leukemia: diagnosis, efficient-targeted drug delivery, and clinical trials . European Journal of Medical Research.
Ibrahim, M.S., Elsayyad, N.M.E., Salama, A., Noshi, S.H.(2023). Utilization of response surface design for development and optimization of rosuvastatin calcium-loaded nano-squarticles for hair growth stimulating VEGF and IGF production: in-vitro and in-vivo evaluation . Drug Development and Industrial Pharmacy. 49. (9). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 580-589.
Ibrahim, Mervat Shafik, Elsayyad, Nihal Mohamed Elmahdy, Salama, Abeer, Noshi, Shereen H. (2023). Utilization of response surface design for development and optimization of rosuvastatin calcium-loaded nano-squarticles for hair growth stimulating VEGF and IGF production: <i>in-vitro</i> and <i>in-vivo</i> evaluation . Drug Development and Industrial Pharmacy.
Noshi, S.H., Ibrahim, M.S., Salama, A., Fathy, I.A., Elsayyad, N.M.E.(2023). Chondroitin Sulphate-Chitosan polyelectrolyte complexes for etorocoxib transdermal delivery: in silico, in vitro and in vivo studies . Pharmaceutical Development and Technology. 28. (8). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 785-798.
Noshi, Shereen H., Ibrahim, Mervat Shafik, Salama, Abeer, Fathy, Iman A., Elsayyad, Nihal Mohamed Elmahdy (2023). Chondroitin Sulphate-Chitosan polyelectrolyte complexes for etorocoxib transdermal delivery: <i>in silico, in vitro and in vivo studies</i> . Pharmaceutical Development and Technology.
Salama, M.M., Aborehab, N.M., El Mahdy, N.M., Zayed, A., Ezzat, S.M.(2023). Nanotechnology in leukemia: diagnosis, efficient-targeted drug delivery, and clinical trials . European Journal of Medical Research. 28. (1).
Nihal Elsayyad(2022). Efficient lung-targeted delivery of risedronate sodium/vitamin D3 conjugated PAMAM-G5 dendrimers for managing osteoporosis: Pharmacodynamics, molecular pathways and metabolomics considerations . Life Sciences. 309. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 121001. Elsevier {BV}
Shereen H. Noshi and Mona Basha and Ghada E. A. Awad and Nihal Mohamed Elmahdy Elsayyad(2022). Miconazole Nitrate loaded Soluplus®-Pluronic® nano-micelles as promising Drug Delivery Systems for Ocular Fungal Infections: In vitro and In vivo Considerations . Research Journal of Pharmacy and Technology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 501--511. A and V Publications
Noshi, S.H., Basha, M., Awad, G.E.A., Elsayyad, N.M.E.(2022). Miconazole Nitrate loaded Soluplus®-Pluronic® nano-micelles as promising Drug Delivery Systems for Ocular Fungal Infections: In vitro and In vivo Considerations . Research Journal of Pharmacy and Technology. 15. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 501-511.
Elsayyad, N.M.E., Gomaa, I., Salem, M.A., Amer, R., El-Laithy, H.M.(2022). Efficient lung-targeted delivery of risedronate sodium/vitamin D3 conjugated PAMAM-G5 dendrimers for managing osteoporosis: Pharmacodynamics, molecular pathways and metabolomics considerations . Life Sciences. 309.
MERVAT SHAFIK IBRAHIM, NIHAL MOHAMED ELMAHDY ELSAYYAD, ABEER SALAMA, SHEREEN H. NOSHI(2021). QUALITY BY DESIGN (QBD) AS A TOOL FOR THE OPTIMIZATION OF INDOMETHACIN FREEZE-DRIED SUBLINGUAL TABLETS: IN VITRO AND IN VIVO EVALUATION . International Journal of Applied Pharmaceutics. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 160--171. Innovare Academic Sciences Pvt Ltd
Chukwuebuka Egbuna and Vijaykumar K. Parmar and Jaison Jeevanandam and Shahira M. Ezzat and Kingsley C. Patrick-Iwuanyanwu and Charles Oluwaseun Adetunji and Johra Khan and Eugene N. Onyeike and Chukwuemelie Zedech Uche and Muhammad Akram and Mervat S. Ibrahim and Nihal M. El Mahdy and Chinaza Godswill Awuchi and Kaliyaperumal Saravanan and Habibu Tijjani and Uchenna Estella Odoh and Mohammed Messaoudi and Jonathan C. Ifemeje and Michael C. Olisah and Nebechi Jane Ezeofor and Chukwudi Jude Chikwendu and Chinwe Gloria Ibeabuchi(2021). Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology . Journal of Toxicology. 2021. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--21. Hindawi Limited
Egbuna, C., Parmar, V.K., Jeevanandam, J., Ezzat, S.M., Patrick-Iwuanyanwu, K.C., Adetunji, C.O., Khan, J., Onyeike, E.N., Uche, C.Z., Akram, M., et al.(2021). Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology . Journal of Toxicology. 2021.
Egbuna, Chukwuebuka, Parmar, Vijaykumar K., Jeevanandam, Jaison, Ezzat, Shahira M., Patrick-Iwuanyanwu, Kingsley C., Adetunji, Charles Oluwaseun, Khan, Johra, Onyeike, Eugene N., Uche, Chukwuemelie Zedech, Akram, Muhammad, et al. (2021). Toxicity of Nanoparticles in Biomedical Application: Nanotoxicology . Journal of Toxicology.
Ibrahim, M.S., Elsayyad, N.M.E., Salama, A., Noshi, S.H.(2021). Quality by design (QBD) as a tool for the optimization of indomethacin freeze-dried sublingual tablets: In vitro and in vivo evaluation . International Journal of Applied Pharmaceutics. 13. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 160-171.
(2020). Concurrent tissue engineering and infection prophylaxis utilising stable dual action amoxicillin loaded scaffolds . Journal of Drug Delivery Science and Technology.
(2020). Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health . ACS Omega.
Elsayyad, Nihal Mohamed Elmahdy, Salama, Abeer, Noshi, Shereen H. (2020). Concurrent tissue engineering and infection prophylaxis utilising stable dual action amoxicillin loaded scaffolds . Journal of Drug Delivery Science and Technology.
Salehi, Bahare, Machin, Laura, Monzote, Lianet, Sharifi-Rad, Javad, Ezzat, Shahira M., Salem, Mohamed A., Merghany, Rana M., El Mahdy, Nihal M., Kilic, Ceyda Sibel, Sytar, Oksana, et al. (2020). Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health . ACS Omega.
Elsayyad, N.M.E., Salama, A., Noshi, S.H.(2020). Concurrent tissue engineering and infection prophylaxis utilising stable dual action amoxicillin loaded scaffolds . Journal of Drug Delivery Science and Technology. 58.
Salehi, B., Machin, L., Monzote, L., Sharifi-Rad, J., Ezzat, S.M., Salem, M.A., Merghany, R.M., El Mahdy, N.M., Klllç, C.S., Sytar, O., et al.(2020). Therapeutic Potential of Quercetin: New Insights and Perspectives for Human Health . ACS Omega. 5. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 11849-11872.
Hanan M. El-Laithy, Alia Badawi, Nevine Shawky Abdelmalak, Nihal Mohamed Elmahdy Elsayyad (2019). Stabilizing excipients for engineered clopidogrel bisulfate procubosome derived in situ cubosomes for enhanced intestinal dissolution: Stability and bioavailability considerations . European Journal of Pharmaceutical Sciences.
(2019). Stabilizing excipients for engineered clopidogrel bisulfate procubosome derived in situ cubosomes for enhanced intestinal dissolution: Stability and bioavailability considerations . European Journal of Pharmaceutical Sciences.
El-Laithy, H.M., Badawi, A., Abdelmalak, N.S., Elsayyad, N.M.E.(2019). Stabilizing excipients for engineered clopidogrel bisulfate procubosome derived in situ cubosomes for enhanced intestinal dissolution: Stability and bioavailability considerations . European Journal of Pharmaceutical Sciences. 136.
El-Laithy, Hanan M., Badawi, Alia, Abdelmalak, Nevine Shawky, Elsayyad, Nihal Mohamed Elmahdy (2019). Stabilizing excipients for engineered clopidogrel bisulfate procubosome derived in situ cubosomes for enhanced intestinal dissolution: Stability and bioavailability considerations . European Journal of Pharmaceutical Sciences.
El-Laithy, H.M., Badawi, A., Abdelmalak, N.S., El-Sayyad, N.(2018). Cubosomes as oral drug delivery systems: A promising approach for enhancing the release of clopidogrel bisulphate in the intestine . Chemical and Pharmaceutical Bulletin. 66. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1165-1173.
El-Laithy, Hanan M., Badawi, Alia, Abdelmalak, Nevine Shawky, El-Sayyad, Nihal (2018). Cubosomes as Oral Drug Delivery Systems: A Promising Approach for Enhancing the Release of Clopidogrel Bisulphate in the Intestine . Chemical and Pharmaceutical Bulletin.
BOOK CHAPTER
Nihal Elsayyad(2022). Lecithin . Antioxidants Effects in Health. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 375--386. Elsevier
Ezzat, S.M., Salem, M.A., Mahdy, N.M.E., Mahfouz, M.M.(2022). Lecithin . Antioxidants Effects in Health the Bright and the Dark Side. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 375-386.
Nihal Elsayyad(2021). Rivastigmine . Naturally Occurring Chemicals Against Alzheimer's Disease. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 93--108. Elsevier
Ezzat, S.M., Salem, M.A., El Mahdy, N.M., Ragab, M.F.(2020). Rivastigmine . Naturally Occurring Chemicals Against Alzheimers Disease. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 93-108.
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