Profile Details

Contact

★★★★★

☆☆☆☆☆

USD 25 /hr

★★★★★

☆☆☆☆☆

Hire Mykola P.

Ukraine

USD 25 /hr

Freelance molecular biologist with strong skills in drug design

Profile Summary

I have been working in the field of rational drug development for 6 years. During this time I studied various methods of molecular modeling, including methods of virtual screening, chemoinformatics, bioinformatics, homologous modeling, etc. I'm currently the author of more than 13 articles on the development of new biologically active molecules for various molecular targets.

Subject Matter Expertise

• ★ Drug Design
• ☆ Molecular Modeling
• ☆ Molecular Docking
• ☆ Biology/Life Sciences
• ☆ Structural Biology
• ☆ Molecular Biology
• ☆ Bioinformatics
• ☆ Medicinal Chemistry

Services

• Writing
• Research

Writing Technical Writing

Research Systematic Literature Review

Work Experience

Junior Research Scientist

Institute of Molecular Biology and Genetics National Academy of Sciences of Ukraine

December 2017 - Present

Education

Master

Kyiv National Taras Shevchenko University

September 2012 - June 2014

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2 . Bioorganic Chemistry.

(2019). Identification and characterization of potential membrane-bound molecular drug targets of methicillin-resistant Staphylococcus aureus using in silico approaches . Biopolymers and Cell.

(2019). Identification of 4‐methoxythieno[2,3‐d]pyrimidines as FGFR1 Inhibitors . Biopolymers and Cell.

(2019). Hit identification of FGFR1 inhibitors using receptor-based virtual screening . Biopolymers and Cell.

(2019). The use of the docking studies with the purpose of searching Potential Antihypertensive Drugs . Research Journal of Pharmacy and Technology.

Protopopov, M.V., Volynets, G.P., Starosyla, S.A., Vdovin, V.S., Lukashov, S.S., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.(2018). Identification of 1,3-thiazole-5-carboxylic acid derivatives as inhibitors of protein kinase CK2 . Current Enzyme Inhibition. 14. (2). p. 152-159.

Protopopov, M.V., Ostrynska, O.V., Starosyla, S.A., Vodolazhenko, M.A., Sirko, S.M., Gorobets, N.Y., Bdzhola, V., Desenko, S.M., Yarmoluk, S.M.(2018). Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors . Molecular Diversity. 22. (4). p. 991-998.

Drapak, I., Perekhoda, L., Vynogradova, O., Protopopov, M., Suleiman, M., Sych, I., Kobzar, N., Kiz, O.(2018). The use of the docking studies with the purpose of searching potential cardioprotectors . Pharmacia. 65. (2). p. 40-46.

Protopopov, M.V., Ostrynska, O.V., Ivanchenko, D.H., Starosyla, S.A., Bdzhola, V.G., Romanenko, M.I., Yarmoluk, S.M.(2017). Search of protein kinase CK2 inhibitors based on purine-2,6-Diones derivatives . Ukrainian Biochemical Journal. 89. (5). p. 32-39.

Protopopov, M.V., Starosyla, S.A., Borovykov, O.V., Sapelkin, V.N., Bilokin, Y.V., Bdzhola, V.G., Yarmoluk, S.M.(2017). Hit identification of CK2 inhibitors by methods of virtual screening . Biopolymers and Cell. 33. (4). p. 291-301.

Zinchenko, A.N., Muzychka, L.V., Smolii, O.B., Bdzhola, V.G., Protopopov, M.V., Yarmoluk, S.M.(2017). Synthesis and biological evaluation of novel amino-substituted derivatives of pyrido[2,3-d]pyrimidine as inhibitors of protein kinase CK2 . Biopolymers and Cell. 33. (5). p. 367-378.

Gudzera, O.I., Golub, A.G., Bdzhola, V.G., Volynets, G.P., Kovalenko, O.P., Boyarshin, K.S., Yaremchuk, A.D., Protopopov, M.V., Yarmoluk, S.M., Tukalo, M.A.(2016). Identification of Mycobacterium tuberculosis leucyl-tRNA synthetase (LeuRS) inhibitors among the derivatives of 5-phenylamino-2H-[1,2,4]triazin-3-one . Journal of Enzyme Inhibition and Medicinal Chemistry. 31. p. 201-207.

Starosyla, S.A., Volynets, G.P., Bdzhola, V.G., Golub, A.G., Protopopov, M.V., Yarmoluk, S.M.(2014). ASK1 pharmacophore model derived from diverse classes of inhibitors . Bioorganic and Medicinal Chemistry Letters. 24. (18). p. 4418-4423.