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Hire Dr. MRIGANKA D.

India

USD 10 /hr

Experienced educator and Researcher with Ph.D. and Post Doc

Profile Summary

Previous Research Experience My PhD research work is mainly focused on the development of flexible Schiff base chelated transition metal coordination complexes towards various biological and electrochemical significance. A good structure-activity relationship is carried out for mimicking of various metalloenzymes i.e, catecholase, glycosidase, protease, nuclease etc. A stringent study on the binding affinity of metal complexes towards biomacromolecules i.e, DNA and Protein are also justified. Cell imaging, anti-proliferative activity, and anti-microbial activity experiment were employed to get fruitful information towards targeted drug therapy. In another phase of my PhD thesis work, I have applied the various electrochemical technique to understand the anti-corrosion activity of these metal complexes. These preliminary outcomes on very good corrosion inhibition efficiency and proper biological significance of these complexes influence me to investigate their probable use in biomedical engineering. In my present Post-Doctoral work, I am currently working in the field of biocatalysis using reconstituted metalloenzyme encapsulated inside some metal-organic framework. Future Research Interest - As I got primary knowledge about the biological significance of metal complexes in my PhD level study, thus my further interest is to investigate the exact and detail roles of metal ions in the living medium also I want to explore the dynamics of metal complexes inside the cellular environment. Apart from this, I have the interest to develop some bioactive anticorrosive biomaterials which can be used as a coating element in biomedical instruments or implants.

Subject Matter Expertise

• ☆ Chemistry
• ☆ Catalysis
• ☆ Coordination Compounds
• ☆ Inorganic Chemistry
• ☆ Metallurgy
• ☆ Corrosion
• ☆ Biomaterials
• ☆ Oxidative Stress & Mitochondrial Function
• ☆ Protein/Enzyme Engineering
• ☆ Medical Implants

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Work Experience

Assisitant Professor

GSFC UNIVERSITY

August 2019 - Present

Visiting Fellow

TIFR Mumbai

February 2018 - Present

Specially Appointed Researcher

Osaka University Japan

August 2017 - October 2017

Research Scholar

IIT Indore

July 2012 - July 2017

Education

PhD Chemistry

IIT Indore

July 2012 - November 2017

M.Sc. Chemsitry

University of Kalyani

August 2010 - August 2012

B.Sc Hons (Chemistry)

Krishnath College

July 2007 - July 2010

Certifications

• Basics of IPR

  WIPO

  November 2017 - Present

Publications

JOURNAL ARTICLE

(2018). Investigation on chemical protease, nuclease and catecholase activity of two copper complexes with flexidentate Schiff base ligands . Inorganica Chimica Acta. 469. p. 111-122.

(2017). A smart organic gel template as metal cation and inorganic anion sensor . Soft Matter. 13. (36). p. 6243-6249.

(2017). Effect on catecholase activity and interaction with biomolecules of metal complexes containing differently tuned 5-substituted ancillary tetrazolato ligands . Polyhedron. 121. p. 155-171.

(2017). Targeted synthesis of cadmium(II) Schiff base complexes towards corrosion inhibition on mild steel . RSC Advances. 7. (77). p. 48569-48585.

Malviya, N., Malviya, N., Mandal, P., Das, M., Ganguly, R., Mukhopadhyay, S.(2017). Nickel tetrazolato complexes synthesized by microwave irradiation: Catecholase like activity and interaction with biomolecules . Journal of Coordination Chemistry. 70. (2). p. 261-278.

(2016). Copper complexes with a flexible piperazinyl arm: nuclearity driven catecholase activity and interactions with biomolecules . Journal of Coordination Chemistry. 69. (24). p. 3619-3637.

(2015). Targeted water soluble copper-tetrazolate complexes: Interactions with biomolecules and catecholase like activities . Dalton Transactions. 44. (46). p. 20154-20167.

(2015). Nickel(II) complexes with a flexible piperazinyl moiety: Studies on DNA and protein binding and catecholase like properties . Dalton Transactions. 44. (5). p. 2299-2310.

Saha, M., Nasani, R., Das, M., Mobin, S.M., Saha, M., Nasani, R., Das, M., Mobin, S.M., Pathak, B., Mukhopadhyay, S.(2014). The effect of remote substitution on the formation of preferential isomers of cobalt(iii)-tetrazolate complexes by microwave assisted cycloaddition . Inorganic Chemistry Frontiers. 1. (8). p. 599-610.

Saha, M., Nasani, R., Das, M., Mahata, A., Pathak, B., Mobin, S.M., Carrella, L.M., Rentschler, E., Mukhopadhyay, S.(2014). Limiting nuclearity in formation of polynuclear metal complexes through [2 + 3] cycloaddition: Synthesis and magnetic properties of tri- and pentanuclear metal complexes . Dalton Transactions. 43. (21). p. 8083-8093.