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Hire Dr. Mohammed Ezzat A.

Egypt

USD 100 /hr

Expert in Pharmacology and Toxicology with a Focus on Drug Development, clinical pharmacy, and pharmacovigilance,

Profile Summary

As a seasoned expert in pharmacology and toxicology, I bring extensive experience in drug development, clinical pharmacy, pharmacovigilance, microbiology, immunology, biochemistry, cell biology, medicinal plant or phytochemistry, public health, and medicinal chemistry across diverse therapeutic areas. With a strong foundation in both preclinical and clinical phases, I have a proven track record of translating scientific research into actionable insights that drive effective drug formulations and regulatory submissions. I have contributed to multiple high-impact research projects focused on pharmacokinetics, toxicological evaluations, and biomarker discovery. My expertise spans across in vitro and in vivo studies, ADMET profiling, genotoxicity testing, and preclinical toxicology, with a particular focus on drug safety and efficacy in early-phase development. I am deeply familiar with ICH and FDA guidelines, ensuring that all projects comply with the highest standards in safety and regulatory expectations. Currently, I am involved in research examining novel therapeutic agents targeting neurological disorders and oncology, focusing on toxicity mechanisms and drug metabolism pathways. My ongoing work aims to bridge the gap between pharmacological research and clinical application, with the goal of minimizing adverse effects and improving patient outcomes. With a PhD in Pharmacology, alongside hands-on experience working with multidisciplinary teams, I offer a comprehensive approach to scientific problem-solving, delivering solutions that are both innovative and practical. My collaborative work across industry and academic settings has strengthened my ability to navigate complex challenges, integrate new methodologies, and maintain a high level of scientific rigor. I am available to offer expert consulting in areas such as preclinical testing, drug safety evaluations, regulatory strategies, and research methodology, supporting projects that require deep pharmacological insight and toxicological expertise.

Subject Matter Expertise

• ☆ Biostatistics
• ☆ Neuroscience
• ☆ Neuropharmacology
• ☆ Pharmacy
• ☆ Pharmacy Education
• ☆ Clinical Pharmacy
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Medicinal Chemistry
• ☆ Drug Design
• ☆ Combinatorial Chemistry
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Drug Development
• ☆ Preclinical Pharmacology
• ☆ Vaccine Development
• ☆ Pharmacovigilance/Drug Safety Monitoring
• ☆ Medical Toxicology
• ☆ Health Informatics
• ☆ Psychiatry
• ☆ Psychopharmacology

Services

• Writing
• Research
• Data & AI

Writing Medical Writing

Research Fact Checking, Scientific and Technical Research, Systematic Literature Review

Data & AI Statistical Analysis, Image Processing, Image Analysis, Data Visualization, Text Mining & Analytics, Data Mining, Data Processing, Data Insights

Work Experience

Lecturer / Investigator

Egyptian Russian University

December 2023 - Present

Assistant Lecturer

Egyptian Russian University

June 2020 - December 2023

Teaching Assistant

Egyptian Russian University

April 2015 - June 2020

Education

PhD (Department of Pharmacology & Toxicology)

Beni-Suef University

September 2020 - December 2023

Master (Department of Pharmacology & Toxicology)

Al-Azhar University

September 2013 - June 2020

Bachelor Science of Pharmacy (Faculty of Pharmacy)

Egyptian Russian University

September 2007 - July 2012

Certifications

• Certificate of Reviewing

  Clinical Interventions in Aging

  https://vm.providesupport.com/dovepress

  January 2024 - December 2024

• Certificate of Reviewing

  European Journal of Medicinal Chemistry

  August 2023 - November 2023

Publications

BOOK CHAPTER

Reham Hassan Mekky, Safaa A. Faheem, Mariam H. Fawzy, Mohammed E. Abo-El Fetoh, Sherouk Hussein Sweilam, Amr El-Demerdash (2025). Natural Remedies for Hypercholesteremia . Natural Remedies in Disease Management and Treatment.

JOURNAL ARTICLE

Reham Hassan Mekky, Mohammed E. Abo‐El Fetoh, Safaa A. Faheem, Abdullah F. Radwan, Mariam H. Fawzy, Aya M. Mustafa, Mohamed A. Said, Daniela Calina, Javad Sharifi‐Rad, William C. Cho (2025). Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets . MedComm.

Yahya A. Almutawif, Haydar M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Hamza M. A. Eid, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo‑El Fetoh, Gaber El-Saber Batiha (2025). Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity . Virology Journal.

Yahya A. Almutawif, Haydar M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Hamza M. A. Eid, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo‑El Fetoh, Gaber El-Saber Batiha (2025). Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity . Virology Journal.

Raed AlRuwaili, Hayder M. Al-kuraishy, Ali I. Al-Gareeb, Ali K. Albuhadily, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo-El Fetoh, Gaber El-Saber Batiha (2025). Targeting of the PI3 K/AKT/GSK3β Pathway in Parkinson's Disease: A Therapeutic Blueprint . Molecular Neurobiology.

Shubam Sudan, Jyotsna Kaushal, Thakur Gurjeet Singh, Mohamed H. Mahmoud, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo-El Fetoh, Gaber El-Saber Batiha (2025). Eco-friendly sensing of hexavalent chromium ions via copper-doped carbon quantum dots: a fluorescent probe for water safety . Microchimica Acta.

AlRuwaili, Raed, Al-kuraishy, Hayder M., Al-Gareeb, Ali I., Albuhadily, Ali K., Alexiou, Athanasios, Papadakis, Marios, Fetoh, Mohammed E. Abo-El, Batiha, Gaber El-Saber (2025). Targeting of the PI3 K/AKT/GSK3β Pathway in Parkinson's Disease: A Therapeutic Blueprint . Molecular Neurobiology.

Khowdiary, Manal M., Al-kuraishy, Hayder M., Al-Gareeb, Ali I., Albuhadily, Ali K., Elhenawy, Ahmed A., Rashwan, Eman K., Alexiou, Athanasios, Papadakis, Marios, Abo-El Fetoh, Mohammed E., Batiha, Gaber El-Saber (2025). The Peripheral Amyloid-β Nexus: Connecting Alzheimer's Disease with Atherosclerosis through Shared Pathophysiological Mechanisms . NeuroMolecular Medicine.

Mekky, Reham Hassan, Abo-El Fetoh, Mohammed E., Faheem, Safaa A., Radwan, Abdullah F., Fawzy, Mariam H., Mustafa, Aya M., Said, Mohamed A., Calina, Daniela, Sharifi-Rad, Javad, Cho, William C. (2025). Transforming Growth Factor-β Pathway: Biological Functions and Therapeutic Targets . MedComm.

Almutawif, Yahya A., Al-kuraishy, Haydar M., Al-Gareeb, Ali I., Albuhadily, Ali K., Eid, Hamza M. A., Alexiou, Athanasios, Papadakis, Marios, Abo-El Fetoh, Mohammed E., Batiha, Gaber El-Saber (2025). Monkeypox virus and type 1 diabetes: a molecular insight into inflammatory signaling and β-cell autoimmunity . Virology Journal.

Elaf R. Alaasam, Ali M. Janabi, Karrar M. Al-Buthabhak, Rihab H. Almudhafar, Najah R. Hadi, Athanasios Alexiou, Marios Papadakis, Mohammed E. Abo-El Fetoh, Dalia Fouad, Gaber El-Saber Batiha (2024). Nephroprotective role of resveratrol in renal ischemia-reperfusion injury: a preclinical study in Sprague-Dawley rats . BMC Pharmacology and Toxicology.

Mohamed K. Elgohary, Mahmoud F. Abo-Ashour, Soha R. Abd El Hadi, Mahmoud A. El Hassab, Mohammed E. Abo-El Fetoh, Hassan Afify, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri (2024). Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation . Bioorganic Chemistry.

Mohammed E. Abo El-Fetoh, Esalm Hassan, Amira Fayed, Laila Ramadan (2024). Empagliflozin protects against indomethacin plus pyloric ligation-induced peptic ulcer in rats . ERU Research Journal.

Elgohary, M.K., Abo-Ashour, M.F., Abd El Hadi, S.R., El Hassab, M.A., Abo-El Fetoh, M.E., Afify, H., Abdel-Aziz, H.A., Abou-Seri, S.M.(2024). Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation . Bioorganic Chemistry. 152.

Maha M. Abdel‐Fattah, Mohammed E. Abo‐El Fetoh, Hassan Afify, Laila A. A. Ramadan, Wafaa R. Mohamed (2023). Probenecid ameliorates testosterone‐induced benign prostatic hyperplasia: Implications of PGE‐2 on ADAM‐17/EGFR/ERK1/2 signaling cascade . Journal of Biochemical and Molecular Toxicology.

Mohamed k elgohary, Soha R. Abd El Hadi, Mahmoud Farid Abo-Ashour, Mohammed E. Abo-El Fetoh, Hassan Afify, Hatem A. Abdel-Aziz, Sahar M. Abou-Seri(2023). Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies . Bioorganic Chemistry. 139. p. 106724. Elsevier {BV}

Mohammed E. Abo-El Fetoh, Maha M. Abdel-Fattah, Hassan Afify, Laila A.A. Ramadan, Wafaa R. Mohamed (2023). Review on EGFR-ERK1/2 signaling cascade: implications on cell proliferation in health and disease . Egyptian Pharmaceutical Journal.

Mohammed E. Abo-El Fetoh, Maha M. Abdel-Fattah, Wafaa R. Mohamed, Laila A. A. Ramadan, Hassan Afify (2023). Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia . Inflammopharmacology.

Abo-El Fetoh, M.E., Abdel-Fattah, M.M., Mohamed, W.R., Ramadan, L.A.A., Afify, H.(2023). Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia . Inflammopharmacology. 31. (1). p. 499-516.

Abo-El Fetoh, Mohammed E. E., Abdel-Fattah, Maha M. M., Mohamed, Wafaa R. R., Ramadan, Laila A. A., Afify, Hassan (2023). Cyclooxygenase-2 activates EGFR-ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia . Inflammopharmacology.

Elgohary, Mohamed K., Abd El Hadi, Soha R., Abo-Ashour, Mahmoud F., Abo-El Fetoh, Mohammed E., Afify, Hassan, Abdel-Aziz, Hatem A., Abou-Seri, Sahar M. (2023). Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies . Bioorganic Chemistry.

Abo-El Fetoh, M.E., Abdel-Fattah, M.M., Afify, H., Ramadan, L.A.A., Mohamed, W.R.(2023). Review on EGFR-ERK1/2 signaling cascade: implications on cell proliferation in health and disease . Egyptian Pharmaceutical Journal. 22. (4). p. 535-544.

Abo-El Fetoh, Mohammed E., Abdel-Fattah, Maha M., Afify, Hassan, Ramadan, Laila A. A., Mohamed, Wafaa R. (2023). Review on EGFR-ERK1/2 signaling cascade: implications on cell proliferation in health and disease . Egyptian Pharmaceutical Journal.

Elgohary, M.K., Abd El Hadi, S.R., Abo-Ashour, M.F., Abo-El Fetoh, M.E., Afify, H., Abdel-Aziz, H.A., Abou-Seri, S.M.(2023). Fragment merging approach for the design of thiazole/thiazolidine clubbed pyrazoline derivatives as anti-inflammatory agents: Synthesis, biopharmacological evaluation and molecular modeling studies . Bioorganic Chemistry. 139.

Abdel-Fattah, M.M., Abo-El Fetoh, M.E., Afify, H., Ramadan, L.A.A., Mohamed, W.R.(2023). Probenecid ameliorates testosterone-induced benign prostatic hyperplasia: Implications of PGE-2 on ADAM-17/EGFR/ERK1/2 signaling cascade . Journal of Biochemical and Molecular Toxicology. 37. (11).

Abdel-Fattah, Maha M., Abo-El Fetoh, Mohammed E., Afify, Hassan, Ramadan, Laila A. A., Mohamed, Wafaa R. (2023). Probenecid ameliorates testosterone-induced benign prostatic hyperplasia: Implications of PGE-2 on ADAM-17/EGFR/ERK1/2 signaling cascade . Journal of Biochemical and Molecular Toxicology.

Mohammed E. Abo-El Fetoh, Maha M. Abdel-Fattah, Wafaa R. Mohamed, Laila A. A. Ramadan, Hassan Afify(2022). Cyclooxygenase-2 activates EGFR–ERK1/2 pathway via PGE2-mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia . Inflammopharmacology. Springer Science and Business Media {LLC}

Abo-El Fetoh, M.E., Helal, G.K., Saleh, I.G., Ewees, M., ElShafey, M., Elnagar, M.R., Akool, E.-S.(2020). Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway . Naunyn-Schmiedeberg's Archives of Pharmacology. 393. (5). p. 897-908.

Abo-El Fetoh, Mohammed E., Helal, Gouda K., Saleh, I. G., Ewees, M., ElShafey, Mohamed, Elnagar, Mohamed R., Akool, El-Sayed (2020). Cyclosporin A activates human hepatocellular carcinoma (HepG2 cells) proliferation: implication of EGFR-mediated ERK1/2 signaling pathway . Naunyn-Schmiedeberg's Archives of Pharmacology.

PREPRINT

Mohammed Aboul Fotouh Hammoda, Maha Mohammed, Wafaa Mohamed, Laila Ramadan, Hassan Afify (2022). Cycloxygenase-2 activates EGFR – ERK1/2 pathway via PGE2 mediated ADAM-17 signaling in testosterone-induced benign prostatic hyperplasia .