Mohammad Tauseef - Freelance Research Methodology Consultant in Illinois, United States

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United States

Profile Summary

RESEARCH SCIENTIST: In Vivo Pharmacology & Drug Discovery

Possess 13 years of experience in pharmaceutical and cardio-pulmonary pharmacology research and experimentation, with a background including:

•	Progressively senior experience at one of the world’s leading research universities.
•	Preclinical research into pharmacology and cardiovascular vascular therapy during inflammatory diseases.
•	Development of standard operating procedures and study protocols.
•	Observation, analysis, and functional evaluation of study results.
•	Small animal surgery and tissue sampling.
•	Establishment and management of complex schedules and timelines.
•	Clear, concise reporting and documentation of all study data.
•	Diverse publications in peer-reviewed journals
•	Pharmacological Development
•	In Vivo Pharmacology
•	Small Animal Surgery
•	Advanced Scientific Writing
•	Cell Based Assays
•	Hypercholesterolemia
•	Study Protocol Development
•	Functional Evaluations
•	Data Management
•	Standard Operating Procedures
•	Pre-Clinical Research
•	Metabolic Diseases
•	Acute Lung Injury/ARDS
•	Inflammatory Diseases
•	Data Analysis

PROFESSIONAL EXPERIENCE

UNIVERSITY OF ILLINOIS AT CHICAGO, Chicago, Illinois • 2007-Present
Leading educational institution and research university, focused on advancing pharmacological sciences.

Research Assistant Professor of Pharmacology (2012-Present)
Promoted to coordinate medical and scientific research in the field of pharmacology and therapeutics, with particular focus on identifying treatments of vascular inflammatory diseases – centered on cardiovascular and pulmonary dysfunctions. Manage the activities of a team of 10 researchers throughout all scientific investigations, guiding research into the role of excessive cytosolic calcium entry, pro-inflammatory cell signaling, and immune sentinel cells in regulation of pulmonary vascular endothelial permeability and inflammation. Utilize research results to petition and win multimillion dollar research grants from the National Heart Lung and Blood Institute (NHLBI) and NIH. Author research proposals, scientific reports and manuscripts, and protocols for the Institutional Animal Care and Use Committee (IACUC). Provide oversight for all aspects of the in vivo pharmacology and mouse vascular endothelial cell isolation facilities. Monitor current trends in scientific technology to identify emerging trends and incorporate the latest developments into the laboratory and its projects.

Selected Achievements:
•	Launched the in vivo pharmacology research program within the laboratory.
•	Introduced state-of-the-art research techniques, including establishing standards and processes. Techniques included liposome mediated gene transfer, mouse isolated perfused lung preparations, and more.
•	Leveraged new techniques such as TIRF microscopy and isolated mouse cell cultures to author and publish research papers in leading biomedical journals.
•	Promoted scientific advancement and knowledge sharing by consistently presenting findings at national and international scientific meetings.
•	Facilitated staff and student growth by providing training and leadership to technical team members, PhD students, and postdoctoral fellows.

Postdoctoral Research Associate (2007-2012)
Recruited to found and develop the in vivo pharmacology research operation within the laboratory, with a primary role in conducting scientific research and design experiments in order to successfully identify the mechanism of pulmonary inflammation and establish a drug target for disease treatment. Generated, recorded, and analyzed scientific data. Compiled findings into presentations for national and international meetings. Authored scientific reports and publications. Prepared and presented seminars.

Selected Achievements:
•	Provided mentorship, support, and coaching to technical personnel and graduate students.
•	Received a promotion to a highly prestigious position within the department.

ADDITIONAL ROLES
•	Senior Research Fellow, Indian Council of Medical Research (ICMR), Department of Physiology, University of Delhi, India (2005-2007): As part of PhD thesis work, performed research into aspirin’s capabilities to restore normal baroreflex function in hypercholesterolemia rats via its antioxidative properties. Executed a study to test the hypothesis that aspirins’ antioxidant effect improved the haemodynamic profile and baroreflex sensitivity in the rat model of hypercholesterolemia. Effectively concluded that aspirin strengthens baroreflex response and circumvents an increase in blood pressure and heart rate, with potential correlation to antioxidative properties.
•	Senior Research Fellow, Center of Scientific & Industrial Research (CSIR), Department of Physiology, University of Delhi, India (2003-2005): As part of PhD thesis work, planned and executed research studies into the antioxidative action of aspirin on endothelial function in hypercholesterolemia rats, to determine the role of aspirin on vascular endothelial changes. Established and tested a hypothesis stating that the antioxidant action of aspirin improves endothelial function in a rat model of hypercholesterolemia. Studied the dose-response relationship of acetylcholine and isoproterenol on isolated aortic tissues to test endothelial function and beta(2)-adrenoceptor activity. Identified an association between aspirin and reduction in free radical stress, demonstrated by lower lipid peroxidation and prevention of reduction in glutathione content.
•	Junior Research Fellow, University Grants Commission (UGC), Department of Pharmacology, Hamdard University (2000-2002): As part of a Master of Pharmacy thesis, conducted research into the effects of aspirin and celecoxib on Diabetes Mellitus and Naphthalene-induced cataracts in rats. Gathered, documented, and analyzed research data to extract relevant correlations.
•	Lecturer, Department of Pharmacology, Faculty of Pharmacy, Hamdard University, Delhi, India (2002-2003): Teaching Clinical Pharmacology and Toxicology courses to PharmD students.

PROFESSIONAL AFFILIATIONS
Member, Editorial Board: The Journal Clinical Research
American Society of Pharmacology and Experimental Therapeutics (ASPET)
Indian Pharmacological Society (IPS)
The American Association for the Advancement of Science (AAAS)
Society for Leukocyte Biology (SLB)

AWARDS, HONORS & FELLOWSHIPS
•	Young Scientist Travel Award, 04/2011, by The American Society for Pharmacology and Experimental Therapeutic (ASPET), Experimental Biology 2011, Washington, DC
•	Gold Medal Prize, College of Medicine (COM) Research 2010, for Best Poster Presentation, University of Illinois, Chicago, US, 11/2010 
•	Michael J. Bristow Postdoctoral Award for First place in Poster Competition, Department of Pharmacology University of Illinois, Chicago, US, 10/2010
•	American Heart Association (AHA) Postdoctoral Fellowship Award, 01/2010 
•	Michael J. Bristow Postdoctoral Award for First place in Poster Competition, Department of Pharmacology University of Illinois, Chicago, US, 10/2009
•	Experimental Biology 2009, “Research Recognition Award” by American Physiological Society, 04/2009
•	Michael J. Bristow Postdoctoral Award for Second place in Poster Competition, Department of Pharmacology University of Illinois, Chicago, US, 07/2008
•	First Place in Poster Competition, Great Lakes Chapter-American Society of Pharmacology and Experimental Therapeutics (GLC-ASPET) Annual Meeting, 06/2008
•	First Place in Poster Competition, International Conference entitled, “Cardio-Pulmonary Regulation in Health and Disease: Molecular and Systemic Integration”, V. P. Chest Institute, University of Delhi, Delhi, India, 02/2007
•	Senior Research Fellowship (SRF) Granted by Indian Council of Medical Research (ICMR), New Delhi, India, 09/2005 – 02/2007
•	Senior Research Fellowship (SRF) Granted by Council of Scientific and Industrial Research (CSIR), New Delhi, India, 11/2003 – 08/2005
•	Graduate Aptitude Test in Engineering (GATE) Research Fellowship Granted by University Grants Commission (UGC), 08/2000 – 07/2002

REVIEWER TO REVIEW ORIGINAL RESEARCH ARTICLES
•	American Journal of Physiology - Lung Cellular and Molecular Physiology
•	Physiological Research
•	Journal of Cardiovascular Pharmacology and Therapeutics
•	Journal of the Renin-Angiotensin-Aldosterone System
•	Journal of Visualized Experiments
•	Plos One
•	Human and Experimental Toxicology

EXTERNAL EXPERT EXAMINER TO REVIEW DOCTORAL THESIS
Appointment of a member of the Board of Examiners by the Vice-Chancellor, Guru Gobind Singh Indraprastha University, New Delhi, India, for evaluation of Ph.D. thesis submitted by a research scholar of the University. The thesis was entitled as, “Neurral Regulation of Cardiovascular Function During Inhibition of Nitric Oxide Synthesis in Rats”, 2012

Subject Matter Expertise

Services

Writing
Consulting
Data & AI
Product Development

Work Experience

Research Assistant Professor

University of Illinois at Chicago

September 2012 - Present

Postdoctoral Research Associate

University of Illinois at Chicago

March 2007 - September 2012

Education

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

The Foreign Pharmacy Graduate Equivalency Examination (FPGEE) Certification (Pharmacy)

National Association of Boards of Pharmacy

April 2015 - Present

PhD (Pharmacology)

University of Delhi

June 2003 - January 2008

Master of Pharmacy (Pharmacology)

Jamia Hamdard (Hamdard University)

September 2000 - August 2002

Bachelor of Pharmacy (Pharmacy)

Jamia Hamdard

August 1996 - August 2000

Certifications

Certification details not provided.

Publications

JOURNAL ARTICLE

(2015). Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype . American Journal of Physiolology Cell Physiol.

(2015). ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension . Vascular Pharmacolology.

(2015). Notch Activation of Ca2+ Signaling Mediates Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension . American Journal of Respiratory Cell Mol Biol.

(2013). Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities . American Journal of Physiology Lung Cell Molecular Physiology.

(2012). TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation . Journal of Experimental Medicine.

(2012). PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity . Circulation Research.

(2012). Cyclic AMP response element-binding protein prevents endothelial permeability increase through transcriptional controlling p190RhoGAP expression . Blood.

(2009). The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin . Journal of Experimental Medicine.

(2008). Antioxidative action of aspirin on endothelial function in hypercholesterolaemic rats . Basic and Clinical Pharmacology and Toxicology.

(2008). Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells . Circulation Research.

Tauseef M, Shahid M, Sharma KK, Fahim M, Basic & clinical pharmacology & toxicology, 2008, vol. 103, no. 4, pp. 314-321 .

Shahid M, Tauseef M, Sharma KK, Fahim M, Experimental physiology, 2008, vol. 93, no. 8, pp. 954-968 .

(2008). In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil . Journal of Pharmacy and Pharmacology.

(2007). Aspirin restores normal baroreflex function in hypercholesterolemic rats by its antioxidative action . European Journal of Pharmacology.

JOURNAL ISSUE

(2013). Mechanisms regulating endothelial permeability . Pulmonary Circulation.

BOOK CHAPTER

(2011). Transient Receptor Potential Channels-mediated calcium signaling in regulating pulmonary edema formation . Recent Advances in Pulmonary Vascular Biology.

(2009). Pulmonary Endothelial Cell Calcium Signaling and Regulation of Lung Vascular Barrier Function . Pulmonary Endothelium.