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Profile Details
Subject Matter Expertise
Services
Writing
Technical Writing,
Copywriting
Research
Market Research,
User Research,
Fact Checking,
Gap Analysis,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Data Visualization,
Data Processing,
Data Insights
Work Experience
Chief Scientific Officer
Nzumbe, Inc.
2017 - Present 
Director of Research
Nzumbe Epigenetics
2013 - 2017
Senior Research Associate
University of Oregon
2009 - 2014
Consultant
Mind Over Data
2005 - 2009
Director and Founder
Mind Over Data XT
2003 - 2005
Assistant Member
St. Jude Children's Research Hospital
2001 - 2003
Instructor
Johns Hopkins School of Medicine
2000 - 2001
Postdoctoral Fellow
Johns Hopkins School of Medicine
1996 - 2000
Education
PhD (Molecular Biology)
University of Oregon
September 1990 - December 1996
BS (Animal Sciences)
University of Illinois
August 1986 - May 1990
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
(2020). LSD1 prevents aberrant heterochromatin formation in Neurospora crassa . Nucleic acids research.
William K. Storck, Sabrina Z. Abdulla, Michael R. Rountree, Vincent T. Bicocca, Eric U. Selker(2020). A Light-Inducible Strain for Genome-Wide Histone Turnover Profiling in Neurospora crassa . Genetics. p. genetics.303217.2020. Genetics Society of America
(2018). Rapid Response and Slow Recovery of the H3K4me3 Epigenomic Marker in the Liver after Light-mediated Phase Advances of the Circadian Clock . Journal of biological rhythms.
Andrew D. Klocko, Miki Uesaka, Tereza Ormsby, Michael R. Rountree, Elizabeth T. Wiles, Keyur K. Adhvaryu, Shinji Honda, Eric U. Selker(2018). Nucleosome Positioning by an Evolutionarily Conserved Chromatin Remodeler Prevents Aberrant {DNA} Methylation in Neurospora . Genetics. 211. (2). p. 563--578. Genetics Society of America
Wiedmeier JE, Ohlrich A, Chu A, Rountree MR, Turker MS(2017). Induction of the long noncoding RNA NBR2 from the bidirectional BRCA1 promoter under hypoxic conditions . Mutation research.
Honda S, Bicocca VT, Gessaman JD, Rountree MR, Yokoyama A, Yu EY, Selker JM, Selker EU(2016). Dual chromatin recognition by the histone deacetylase complex HCHC is required for proper DNA methylation in Neurospora crassa . Proceedings of the National Academy of Sciences of the United States of America.
Klocko AD, Rountree MR, Grisafi PL, Hays SM, Adhvaryu KK, Selker EU(2015). Neurospora importin α is required for normal heterochromatic formation and DNA methylation . PLoS genetics.
Jamieson K, Rountree MR, Lewis ZA, Stajich JE, Selker EU(2013). Regional control of histone H3 lysine 27 methylation in Neurospora . Proceedings of the National Academy of Sciences of the United States of America.
Smith KM, Dobosy JR, Reifsnyder JE, Rountree MR, Anderson DC, Green GR, Selker EU(2010). H2B- and H3-specific histone deacetylases are required for DNA methylation in Neurospora crassa . Genetics.
Rountree MR, Selker EU(2010). DNA methylation and the formation of heterochromatin in Neurospora crassa . Heredity.
Reese BE, Bachman KE, Baylin SB, Rountree MR(2003). The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1 . Molecular and Cellular Biology.
Selker EU, Freitag M, Kothe GO, Margolin BS, Rountree MR, Allis CD, Tamaru H(2002). Induction and maintenance of nonsymmetrical DNA methylation in Neurospora . Proceedings of the National Academy of Sciences of the United States of America.
Galm O, Rountree MR, Bachman KE, Jair KW, Baylin SB, Herman JG(2002). Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density . Genome research.
Bachman KE, Rountree MR, Baylin SB(2001). Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin . The Journal of Biological Chemistry.
Rountree MR, Bachman KE, Herman JG, Baylin SB(2001). DNA methylation, chromatin inheritance, and cancer . Oncogene.
Baylin SB, Esteller M, Rountree MR, Bachman KE, Schuebel K, Herman JG(2001). Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer . Human molecular genetics.
Rountree MR, Bachman KE, Baylin SB(2000). DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci . Nature genetics.
Rountree MR, Selker EU(1997). DNA methylation inhibits elongation but not initiation of transcription in Neurospora crassa . Genes & development.
Cambareri EB, Foss HM, Rountree MR, Selker EU, Kinsey JA(1996). Epigenetic control of a transposon-inactivated gene in Neurospora is dependent on DNA methylation . Genetics.
Miao VP, Rountree MR, Selker EU(1995). Ectopic integration of transforming DNA is rare among neurospora transformants selected for gene replacement . Genetics.
Miao VP, Singer MJ, Rountree MR, Selker EU(1994). A targeted-replacement system for identification of signals for de novo methylation in Neurospora crassa . Molecular and cellular biology.
BOOK CHAPTER
(2008). Genome Defense: The Neurospora Paradigm. Epigenomics.
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