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Hire Dr. Marijn L.

United States

USD 100 /hr

Principal investigator | IRB member | Human neuropsychopharmacology of psychiatric disorders | Clinical trial specialist

Profile Summary

I have close to 20 years of experience in human neuropsychopharmacological research at the Department of Psychiatry and Behavioral Sciences. I am a seasoned Assistant Professor (PhD) and Principal Investigator on research of basic mechanisms of psychiatric disorders, as well as designing and conducting proof-of concept studies, and phase 1 to 3 clinical trials that highlight biomarkers to show target engagement, safety, and efficacy. I have published my work in 44 peer-reviewed papers in international journals.

Subject Matter Expertise

• ★ Clinical Trials
• ★ Psychiatry
• ★ Psychopharmacology
• ☆ IRB Applications
• ☆ Clinical Trial Design
• ☆ Neuropsychiatry
• ☆ Regulatory Writing
• ☆ Clinical Trial Documentation
• ☆ Clinical Trial Protocol Writing

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Clinical Trial Documentation, Technical Writing, Copywriting, Newswriting

Research Market Research, User Research, Meta-Research, Feasibility Study, Fact Checking, Gap Analysis, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting, Regulatory Consulting

Data & AI Statistical Analysis, Data Visualization, Big Data Analytics, Data Processing

Work Experience

Assistant Research Professor / Principal Investigator clinical trials and clinical research

Baylor College of Medicine, Depart. Psychiatry and Behavioral Sciences, and Michael E. DeBakey VA Medical Center

October 2013 - Present

Assistant Professor

Baylor College of Medicine

September 2013 - Present

Education

PhD, Neuropsychopharmacology

Utrecht University

September 1999 - May 2004

Ph.D. (Pharmaceutical Sciences)

Utrecht University

1999 - 2004

M.Sc. (Social Sciences)

Utrecht University

1994 - 1999

Certifications

• Google Project Management

  coursera

  https://www.coursera.org/account/accomplishments/specialization/certificate/ZYUGKBQSHNVJ

  January 2022 - Present

Publications

JOURNAL ARTICLE

Simonetti, A., Lijffijt, M., Kahlon, R.S., Gandy, K., Arvind, R.P., Amin, P., Arciniegas, D.B., Swann, A.C., Soares, J.C., Saxena, K.(2019). Early and late cortical reactivity to passively viewed emotional faces in pediatric bipolar disorder . Journal of Affective Disorders. 253. p. 240-247.

O'Brien, B., Green, C.E., Al-Jurdi, R., Chang, L., Lijffijt, M., Iqbal, S., Iqbal, T., Swann, A.C.(2019). Bayesian adaptive randomization trial of intravenous ketamine for veterans with late-life, treatment-resistant depression . Contemporary Clinical Trials Communications. 16.

O’Brien, B., Lijffijt, M., Wells, A., Swann, A.C., Mathew, S.J.(2019). The impact of childhood maltreatment on intravenous ketamine outcomes for adult patients with treatment-resistant depression . Pharmaceuticals. 12. (3).

Lijffijt, M., O'Brien, B., Salas, R., Mathew, S.J., Swann, A.C.(2019). Interactions of immediate and long-term action regulation in the course and complications of bipolar disorder . Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 374. (1766). p. 20180132.

Marijn Lijffijt, Sanjay J. Mathew(2017). Neurometabolic Abnormalities in Treatment-Resistant Depression . American Journal of Psychiatry. 174. (1). p. 3--5. American Psychiatric Publishing

Lijffijt, M., Lane, S.D., Mathew, S.J., Stanford, M.S., Swann, A.C.(2017). Heightened early-attentional stimulus orienting and impulsive action in men with antisocial personality disorder . European Archives of Psychiatry and Clinical Neuroscience. 267. (7). p. 697-707.

Mathew, S.J., Lijffijt, M.(2017). Neurometabolic abnormalities in treatment-resistant depression . American Journal of Psychiatry. 174. (1). p. 3-5.

Marijn Lijffijt, Scott D. Lane, Sanjay J. Mathew, Matthew S. Stanford, Alan C. Swann(2016). Heightened early-attentional stimulus orienting and impulsive action in men with antisocial personality disorder . European Archives of Psychiatry and Clinical Neuroscience. 267. (7). p. 697--707. Springer Nature

Marijn Lijffijt, Scott D. Lane, F. Gerard Moeller, Joel L. Steinberg, Alan C. Swann(2015). Trait impulsivity and increased pre-attentional sensitivity to intense stimuli in bipolar disorder and controls . Journal of Psychiatric Research. 60. p. 73--80. Elsevier {BV}

Hu, K., Lijffijt, M., Beauchaine, T.P., Fan, Z., Shi, H., He, S.(2015). Influence of empathetic pain processing on cognition in schizophrenia . European Archives of Psychiatry and Clinical Neuroscience. 265. (7). p. 623-631.

Lijffijt, M., Lane, S.D., Moeller, F.G., Steinberg, J.L., Swann, A.C.(2015). Trait impulsivity and increased pre-attentional sensitivity to intense stimuli in bipolar disorder and controls . Journal of Psychiatric Research. 60. p. 73-80.

Marijn Lijffijt, Kesong Hu, Alan C. Swann(2014). Stress Modulates Illness-Course of Substance Use Disorders: A Translational Review . Frontiers in Psychiatry. 5. Frontiers Media {SA}

Lijffijt, M., Rourke, E.D., Swann, A.C., Zunta-Soares, G.B., Soares, J.C.(2014). Illness-course modulates suicidality-related prefrontal gray matter reduction in women with bipolar disorder . Acta Psychiatrica Scandinavica. 130. (5). p. 374-387.

Marijn Lijffijt, Kesong Hu, Theodore P. Beauchaine, Zhiwei Fan, Hui Shi, Shuchang He(2014). Influence of empathetic pain processing on cognition in schizophrenia . European Archives of Psychiatry and Clinical Neuroscience. 265. (7). p. 623--631. Springer Nature

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Joel L. Steinberg, F. Gerard Moeller(2013). Antisocial personality disorder and borderline symptoms are differentially related to impulsivity and course of illness in bipolar disorder . Journal of Affective Disorders. 148. (2-3). p. 384--390. Elsevier {BV}

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Blake Cox, Joel L. Steinberg, F. Gerard Moeller(2013). Norepinephrine and impulsivity: effects of acute yohimbine . Psychopharmacology. 229. (1). p. 83--94. Springer Nature

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Joel L. Steinberg, Michelle D. Acas, Blake Cox, F. Gerard Moeller(2013). Pre-attentive information processing and impulsivity in bipolar disorder . Journal of Psychiatric Research. 47. (12). p. 1917--1924. Elsevier {BV}

Swann, A.C., Lijffijt, M., Lane, S.D., Cox, B., Steinberg, J.L., Moeller, F.G.(2013). Norepinephrine and impulsivity: Effects of acute yohimbine . Psychopharmacology. 229. (1). p. 83-94.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2013). Antisocial personality disorder and borderline symptoms are differentially related to impulsivity and course of illness in bipolar disorder . Journal of Affective Disorders. 148. (2-3). p. 384-390.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Acas, M.D., Cox, B., Moeller, F.G.(2013). Pre-attentive information processing and impulsivity in bipolar disorder . Journal of Psychiatric Research. 47. (12). p. 1917-1924.

Marijn Lijffijt, Blake Cox, Michelle D. Acas, Scott D. Lane, F. Gerard Moeller, Alan C. Swann(2012). Differential relationships of impulsivity or antisocial symptoms on P50, N100, or P200 auditory sensory gating in controls and antisocial personality disorder . Journal of Psychiatric Research. 46. (6). p. 743--750. Elsevier {BV}

Lijffijt, M., Cox, B., Acas, M.D., Lane, S.D., Moeller, F.G., Swann, A.C.(2012). Differential relationships of impulsivity or antisocial symptoms on P50, N100, or P200 auditory sensory gating in controls and antisocial personality disorder . Journal of Psychiatric Research. 46. (6). p. 743-750.

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Joel L. Steinberg, F. Gerard Moeller(2011). Interacting mechanisms of impulsivity in bipolar disorder and antisocial personality disorder . Journal of Psychiatric Research. 45. (11). p. 1477--1482. Elsevier {BV}

Marijn Lijffijt, Alan C Swann, Scott D Lane, Kimberly L Kjome, Joel L Steinberg, F Gerard Moeller(2011). Criminal conviction, impulsivity, and course of illness in bipolar disorder . Bipolar Disorders. 13. (2). p. 173--181. Wiley-Blackwell

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2011). Interacting mechanisms of impulsivity in bipolar disorder and antisocial personality disorder . Journal of Psychiatric Research. 45. (11). p. 1477-1482.

Swann, A.C., Lijffijt, M., Lane, S.D., Kjome, K.L., Steinberg, J.L., Moeller, F.G.(2011). Criminal conviction, impulsivity, and course of illness in bipolar disorder . Bipolar Disorders. 13. (2). p. 173-181.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2010). Interactions between bipolar disorder and antisocial personality disorder in trait impulsivity and severity of illness . Acta Psychiatrica Scandinavica. 121. (6). p. 453-461.

MARIJN LIJFFIJT, ALAN C. SWANN, JOEL L. STEINBERG, GERARD F. MOELLER(2009). Continuum of depressive and manic mixed states in patients with bipolar disorder: quantitative measurement and clinical features . World Psychiatry. 8. (3). p. 166--172. Wiley-Blackwell

Marijn Lijffijt, Scott D. Lane, Stacey L. Meier, Nash N. Boutros, Scott Burroughs, Joel L. Steinberg, F. Gerard Moeller, Alan C. Swann(2009). P50, N100, and P200 sensory gating: Relationships with behavioral inhibition, attention, and working memory . Psychophysiology. 46. (5). p. 1059--1068. Wiley-Blackwell

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Joel L. Steinberg, F. Gerard Moeller(2009). Trait impulsivity and response inhibition in antisocial personality disorder . Journal of Psychiatric Research. 43. (12). p. 1057--1063. Elsevier {BV}

Marijn Lijffijt, F. Gerard Moeller, Nash N. Boutros, S. Burroughs, Joel L. Steinberg, Scott D. Lane, Alan C. Swann(2009). A Pilot Study Revealing Impaired P50 Gating in Antisocial Personality Disorder . The Journal of Neuropsychiatry and Clinical Neurosciences. 21. (3). p. 328--331. American Psychiatric Publishing

Marijn Lijffijt, Alan C. Swann, Scott D. Lane, Joel L. Steinberg, F. Gerard Moeller(2009). Severity of bipolar disorder is associated with impairment of response inhibition . Journal of Affective Disorders. 116. (1-2). p. 30--36. Elsevier {BV}

Marijn Lijffijt, F. Gerard Moeller, Nash N. Boutros, Joel L. Steinberg, Stacey L. Meier, Scott D. Lane, Alan C. Swann(2009). Diminished P50, N100 and P200 auditory sensory gating in bipolar I disorder . Psychiatry Research. 167. (3). p. 191--201. Elsevier {BV}

Marijn Lijffijt, Alan C Swann, Scott D Lane, Joel L Steinberg, F Gerard Moeller(2009). Increased trait-like impulsivity and course of illness in bipolar disorder . Bipolar Disorders. 11. (3). p. 280--288. Wiley-Blackwell

Marijn Lijffijt, F. Gerard Moeller, Nash N. Boutros, Scott Burroughs, Scott D. Lane, Joel L. Steinberg, Alan C. Swann(2009). The Role of Age, Gender, Education, and Intelligence in P50, N100, and P200 Auditory Sensory Gating . Journal of Psychophysiology. 23. (2). p. 52--62. Hogrefe Publishing Group

Lijffijt, M., Moeller, F.G., Boutros, N.N., Burroughs, S., Lane, S.D., Steinberg, J.L., Swann, A.C.(2009). The role of age, gender, education and intelligence in P50, N100 and P200 auditory sensory gating . Journal of Psychophysiology. 23. (2). p. 52-62.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2009). Increased trait-like impulsivity and course of illness in bipolar disorder . Bipolar Disorders. 11. (3). p. 280-288.

Lijffijt, M., Moeller, F.G., Boutros, N.N., Steinberg, J.L., Meier, S.L., Lane, S.D., Swann, A.C.(2009). Diminished P50, N100 and P200 auditory sensory gating in bipolar I disorder . Psychiatry Research. 167. (3). p. 191-201.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2009). Severity of bipolar disorder is associated with impairment of response inhibition . Journal of Affective Disorders. 116. (1-2). p. 30-36.

Swann, A.C., Lijffijt, M., Lane, S.D., Steinberg, J.L., Moeller, F.G.(2009). Trait impulsivity and response inhibition in antisocial personality disorder . Journal of Psychiatric Research. 43. (12). p. 1057-1063.

Lijffijt, M., Moeller, F.G., Boutros, N.N., Burroughs, S., Steinberg, J.L., Lane, S.D., Swann, A.C.(2009). A pilot study revealing impaired P50 gating in antisocial personality disorder . Journal of Neuropsychiatry and Clinical Neurosciences. 21. (3). p. 328-331.

Swann, A.C., Steinberg, J.L., Lijffijt, M., Moeller, F.G.(2009). Continuum of depressive and manic mixed states in patients with bipolar disorder: Quantitative measurement and clinical features . World Psychiatry. 8. (3). p. 166-172.

Lijffijt, M., Lane, S.D., Meier, S.L., Boutros, N.N., Burroughs, S., Steinberg, J.L., Gerard Moeller, F., Swann, A.C.(2009). P50, N100, and P200 sensory gating: Relationships with behavioral inhibition, attention, and working memory . Psychophysiology. 46. (5). p. 1059-1068.

Marijn Lijffijt, Alan C. Swann, Joel L. Steinberg, F. Gerard Moeller(2008). Impulsivity: Differential relationship to depression and mania in bipolar disorder . Journal of Affective Disorders. 106. (3). p. 241--248. Elsevier {BV}

Swann, A.C., Steinberg, J.L., Lijffijt, M., Moeller, F.G.(2008). Impulsivity: Differential relationship to depression and mania in bipolar disorder . Journal of Affective Disorders. 106. (3). p. 241-248.

Marijn Lijffijt, J. Leon Kenemans, Annemiek ter Wal, Elise H. Quik, C. Kemner, Herman Westenberg, Marinus N. Verbaten, Herman van Engeland(2006). Dose-related effect of methylphenidate on stopping and changing in children with attention-deficit/hyperactivity disorder . European Psychiatry. 21. (8). p. 544--547. Elsevier {BV}

Lijffijt, M., Kenemans, J.L., Wal, A.t., Quik, E.H., Kemner, C., Westenberg, H., Verbaten, M.N., Engeland, H.v.(2006). Dose-related effect of methylphenidate on stopping and changing in children with attention-deficit/hyperactivity disorder . European Psychiatry. 21. (8). p. 544-547.

Marijn Lijffijt, P. Sytze van Dam, Channa F. de Winter, Rehana de Vries, Jeroen van der Grond, Madeleine L. Drent, J. Leon Kenemans, André Aleman, Edward H.F. de Haan, Hans P.F. Koppeschaar(2005). Childhood-onset growth hormone deficiency, cognitive function and brain N-acetylaspartate . Psychoneuroendocrinology. 30. (4). p. 357--363. Elsevier {BV}

Marijn Lijffijt, Hervé Caci, J. Leon Kenemans(2005). Validation of the Dutch translation of the I7 questionnaire . Personality and Individual Differences. 38. (5). p. 1123--1133. Elsevier {BV}

Lijffijt, M., Caci, H., Kenemans, J.L.(2005). Validation of the Dutch translation of the I<inf>7</inf> questionnaire . Personality and Individual Differences. 38. (5). p. 1123-1133.

Marijn Lijffijt, J. Leon Kenemans, Marinus N. Verbaten, Herman van Engeland(2005). A Meta-Analytic Review of Stopping Performance in Attention-Deficit/Hyperactivity Disorder: Deficient Inhibitory Motor Control? . Journal of Abnormal Psychology. 114. (2). p. 216--222. American Psychological Association ({APA})

Lijffijt, M., Kenemans, J.L., Verbaten, M.N., Van Engeland, H.(2005). A meta-analytic review of stopping performance in attention-deficit/ hyperactivity disorder: Deficient inhibitory motor control? . Journal of Abnormal Psychology. 114. (2). p. 216-222.

Kenemans, J.L., Bekker, E.M., Lijffijt, M., Overtoom, C.C.E., Jonkman, L.M., Verbaten, M.N.(2005). Attention deficit and impulsivity: Selecting, shifting, and stopping . International Journal of Psychophysiology. 58. (1). p. 59-70.

Sytze Van Dam, P., De Winter, C.F., De Vries, R., Van Der Grond, J., Drent, M.L., Lijffijt, M., Leon Kenemans, J., Aleman, A., De Haan, E.H.F., Koppeschaar, H.P.F.(2005). Childhood-onset growth hormone deficiency, cognitive function and brain N-acetylaspartate . Psychoneuroendocrinology. 30. (4). p. 357-363.

Lijffijt, M., Bekker, E.M., Quik, E.H., Bakker, J., Kenemans, J.L., Verbaten, M.N.(2004). Differences between low and high trait impulsivity are not associated with differences in inhibitory motor control . Journal of Attention Disorders. 8. (1). p. 25-32.

Lijffijt, M., Van Dam, P.S., Kenemans, J.L., Koppeschaar, H.P.F., De Vries, W.R., Drent, M.L., Wittenberg, A., Kemner, C.(2003). Somatotropic-axis deficiency affects brain substrates of selective attention in childhood-onset growth hormone deficient patients . Neuroscience Letters. 353. (2). p. 123-126.

Marijn Lijffijt, J. Leon Kenemans, Gert Camfferman, Marinus N. Verbaten(2002). Split-Second Sequential Selective Activation in Human Secondary Visual Cortex . Journal of Cognitive Neuroscience. 14. (1). p. 48--61. {MIT} Press - Journals

Kenemans, J.L., Lijffijt, M., Camfferman, G., Verbaten, M.N.(2002). Split-second sequential selective activation in human secondary visual cortex . Journal of Cognitive Neuroscience. 14. (1). p. 48-61.

Kenemans, J.L., Baas, J.M.P., Mangun, G.R., Lijffijt, M., Verbaten, M.N.(2000). On the processing of spatial frequencies as revealed by evoked-potential source modeling . Clinical Neurophysiology. 111. (6). p. 1113-1123.

OTHER

Marijn Lijffijt, Therese A. Kosten, Colin N. Haile, Alan C. Swann(2016). Alcohol-Related Disorders . Neurobiology of Addictions. p. 105--137. Oxford University Press

Marijn Lijffijt(2016). Stress and Addiction . Neurobiology of Addictions. p. 153--175. Oxford University Press

Marijn Lijffijt, Alan C. Swann, F. Gerard Moeller Biological Substrate of Personality Traits Associated with Aggression . The SAGE Handbook of Personality Theory and Assessment: Volume 1 — Personality Theories and Models. p. 334--356. {SAGE} Publications Ltd

BOOK CHAPTER

Lijffijt, M.(2008). Biological substrate of personality traits associated with aggression . The SAGE Handbook of Personality Theory and Assessment: Volume 1 - Personality Theories and Models. p. 334-356.