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Hire Dr. Maria Z.

Colombia

Proactive, collaborative and hard-worker person who enjoy new challenges in life and biological sciences.

Profile Summary

I am a highly qualified and motivated scientific in the area of immunogenetics. My main interest is to unravel the mechanism behind immune associated disorders, cancer and infectious diseases to hopefully develop or improve treatments. I am currently finishing my PhD at the Department of genetics at the University medical Center of Groningen. My research focuses in understanding the role of genes in the development of immune mediated diseases. During the course of my career, I have been learning the most recent concepts and techniques in cell culture, molecular biology, immunology, proteomics, clinical diagnostic and genetics. I have been working in multidisciplinary environments, which have improved my knowledge, communication and team-work abilities. I consider myself a proactive, collaborative and hard-worker person who enjoy new challenges. I am about to finish my PhD and I searching for job opportunities, particularly in pharmaceutical companies where I could impact positively the patient care with my expertise.

Subject Matter Expertise

• ★ Molecular Biology
• ★ Cell Signaling Pathways
• ☆ Immunoassay

Services

• Writing
• Research

Writing Clinical Trial Documentation, Technical Writing

Research Systematic Literature Review, Secondary Data Collection

Work Experience

In vitro validation of genes associated with celiac disease, using immune cells derived from blood and intestine, modulation of gene expression (siRNA, shRNA), evaluation of phenotypic effects (permeability, immunoassays), transcriptional and epigenetic (qPCR, RNAseq, chipseq)

University Medical Center Groningen (UMCG)

January 2013 - Present

Education

PhD

UMCG-University of Groningen

October 2013 - Present

Phd Student (Genetics)

Universiteit Groningen UMCG Afdeling Interne Geneeskunde

October 2013 - Present

Certifications

• Certification details not provided.

Publications

OTHER

Maria Zorro, Adriaan van der Graaf, Annique Claringbould, Urmo Vosa, Raul Aguirre-Gamboa, Chan Li, Joram Mooiweer, Isis Ricano-Ponce, Zuzanna Borek, Frits Koning, et al.(2020). Systematic prioritization of candidate genes in disease loci identifies {TRAFD}1 as a master regulator of {IFN}$\upgamma$ signalling in celiac disease . Cold Spring Harbor Laboratory

JOURNAL ARTICLE

(2019). Immunochip meta-analysis in European and Argentinian populations identifies two novel genetic loci associated with celiac disease . Eur J Hum Genet.

(2019). Deconvolution of bulk blood eQTL effects into immune cell subpopulations . [].

(2018). A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease . Eur J Gastroenterol Hepatol.

(2018). Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses . Nat Immunol.

(2016). Differential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits . Cell Rep.

(2016). Refined mapping of autoimmune disease associated genetic variants with gene expression suggests an important role for non-coding RNAs . J Autoimmun.

(2016). Encephalitozoon intestinalis Inhibits Dendritic Cell Differentiation through an IL-6-Dependent Mechanism . Front Cell Infect Microbiol.

(2016). Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis . Hum Mol Genet.

(2014). Small and Long Regulatory RNAs in the Immune System and Immune Diseases . Front Immunol.

(2009). In vitro susceptibility of Trypanosoma cruzi strains from Santander, Colombia, to hexadecylphosphocholine (miltefosine), nifurtimox and benznidazole. Biomedica.

CONFERENCE PAPER

(2019). Tissue alarmins and adaptive cytokine induce dynamic and distinct transcriptional responses in tissue-resident intraepithelial cytotoxic T lymphocytes. 18th international Celiac disease symposium.