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USD 25 /hr

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Hire Dr. Manas D.

India

USD 25 /hr

Freelancer Bioinformatician and Immunologist, Expert in Immunological study design, NGS analysis, Structural Bioinfo.

Profile Summary

Subject Matter Expertise

Services

Writing
Research
Consulting
Data & AI

Writing Technical Writing

Research Market Research, User Research, Meta-Research, Fact Checking, Gap Analysis, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Big Data Analytics

Work Experience

Postdoctoral Fellow

ICMR-RMRIMS

March 2018 - Present

Education

PhD, Biochemistry

Calcutta University, India

March 2013 - January 2018

Certifications

Certification details not provided.

Publications

JOURNAL ARTICLE

Raj Kishor Pandey, Manas Ranjan Dikhit, Kiran Bharat Lokhande, Krishna Pandey, Pradeep Das, Sanjiva Bimal (2021). An immunoprophylactic evaluation of Ld-ODC derived HLA-A0201 restricted peptides against visceral leishmaniasis . Journal of Biomolecular Structure and Dynamics.

Maneesh Kumar, Roshan Kamal Topno, Manas Ranjan Dikhit, Bhawana, Ganesh Chandra Sahoo, Major Madhukar, Krishna Pandey, Pradeep Das(2019). Molecular docking studies of chloroquine and its derivatives against P23 pro‐zbd domain of chikungunya virus: Implication in designing of novel therapeutic strategies . Journal of Cellular Biochemistry. 120. (10). p. 18298--18308. Wiley

Anurag Singh Chauhan, Md Yousuf Ansari, Rani Mansuri, Manas Ranjan Dikhit, Vahab Ali, Ganesh Chandra Sahoo, Pradeep Das(2018). Computational elucidation, mutational and hot spot-based designing of potential inhibitors against human acid-sensing ion channels (hASIC-1a) to treat various physiological conditions . Journal of Biomolecular Structure and Dynamics. 36. (13). p. 3513--3530. Informa {UK} Limited

Amit, A., Dikhit, M.R., Mahantesh, V., Chaudhary, R., Singh, A.K., Singh, A., Singh, S.K., Das, V.N.R., Pandey, K., Ali, V., et al.(2016). Immunomodulation mediated through Leishmania donovani protein disulfide isomerase by eliciting CD8+ T-cell in cured visceral leishmaniasis subjects and identification of its possible HLA class-1 restricted T-cell epitopes . Journal of Biomolecular Structure and Dynamics. p. 1-13.

Vijayamahantesh, Amit, A., Dikhit, M.R., Pandey, R.K., Singh, K., Mishra, R., Das, V.N.R., Das, P., Bimal, S.(2016). Elevated serum ADA activity as a marker for diagnosis and prognosis of visceral leishmaniasis and post Kala-Azar Dermal leishmaniasis in Indian patients . PLoS ONE. 11. (5).

Vijayamahantesh, Amit, A., Kumar, S., Dikhit, M.R., Jha, P.K., Singh, A.K., Sinha, K.K., Pandey, K., Das, V.N.R., Das, P., et al.(2016). Up regulation of A<inf>2B</inf> adenosine receptor on monocytes are crucially required for immune pathogenicity in Indian patients exposed to Leishmania donovani . Cytokine. 79. p. 38-44.

Ansari, M.Y., Equbal, A., Dikhit, M.R., Mansuri, R., Rana, S., Ali, V., Sahoo, G.C., Das, P.(2016). Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors . International Journal of Biological Macromolecules. 83. p. 78-96.

Dikhit, M.R., Purkait, B., Singh, R., Sahoo, B.R., Kumar, A., Kar, R.K., Ansari, M.Y., Saini, S., Abhishek, K., Sahoo, G.C., et al.(2016). Activity of a novel sulfonamide compound 2-nitro-N-(Pyridin-2-ylmethyl)benzenesulfonamide against Leishmania donovani . Drug Design, Development and Therapy. 10. p. 1753-1761.

Sahoo, B.R., Dikhit, M.R., Bhoi, G.K., Maharana, J., Lenka, S.K., Dubey, P.K., Tiwari, D.K.(2015). Understanding the distinguishable structural and functional features in zebrafish TLR3 and TLR22, and their binding modes with fish dsRNA viruses: An exploratory structural model analysis . Amino Acids. 47. (2). p. 381-400.

Dikhit, M.R., Kumar, S., Vijaymahantesh, Sahoo, B.R., Mansuri, R., Amit, A., Yousuf Ansari, M., Sahoo, G.C., Bimal, S., Das, P.(2015). Computational elucidation of potential antigenic CTL epitopes in Ebola virus . Infection, Genetics and Evolution. 36. p. 369-375.

Moharana, K.C., Dikhit, M.R., Sahoo, B.R., Sahoo, G.C., Das, P.(2015). GAOPP: Operon prediction in prokaryotes using genetic algorithm . Current Bioinformatics. 10. (3). p. 299-305.

Yadav, A., Amit, A., Chaudhary, R., Chandel, A.S., Mahantesh, V., Suman, S.S., Singh, S.K., Dikhit, M.R., Ali, V., Rabidas, V., et al.(2015). Leishmania donovani: Impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis . International Journal for Parasitology. 45. (1). p. 33-42.

Das, P., Amit, A., Singh, S.K., Chaudhary, R., Dikhit, M.R., yadav, A., Pandey, K., Das, V.N.R., Sundram, S., Das, P., et al.(2015). Leishmania donovani phosphoproteins pp41 and pp29 re-establishes host protective immune response in visceral leishmaniasis . Parasitology International. 64. (1). p. 18-25.

Zaidi, A., Singh, K.P., Anwar, S., Suman, S.S., Equbal, A., Singh, K., Dikhit, M.R., Bimal, S., Pandey, K., Das, P., et al.(2015). Interaction of frataxin, an iron binding protein, with IscU of Fe-S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani . Biochimie. 115. p. 120-135.

Sahoo GC, Yousuf Ansari M, Dikhit MR, Kannan M, Rana S, Das P, Journal of biomolecular structure & dynamics, 2014, vol. 32, no. 5, pp. 709-729 .

Sahoo BR, Maharana J, Bhoi GK, Lenka SK, Patra MC, Dikhit MR, Dubey PK, Pradhan SK, Behera BK, Molecular bioSystems, 2014 .

Anwar, S., Dikhit, M.R., Singh, K.P., Kar, R.K., Zaidi, A., Sahoo, G.C., Roy, A.K., Nozaki, T., Das, P., Ali, V.(2014). Interaction between Nbp35 and Cfd1 proteins of cytosolic Fe-S cluster assembly reveals a stable complex formation in Entamoeba histolytica . PLoS ONE. 9. (10).

Sahoo, G.C., Yousuf Ansari, M., Dikhit, M.R., Kannan, M., Rana, S., Das, P.(2014). Structure prediction of gBP21 protein of L. donovani and its molecular interaction . Journal of Biomolecular Structure and Dynamics. 32. (5). p. 709-729.

Sahoo, G.C., Rani, M., Ansari, M.Y., Jha, C., Rana, S., Dikhit, M.R., Moharana, K.C., Kumar, R., Das, P.(2014). Structure, evolution and virtual screening of NDM-1 strain from Kolkata . International Journal of Bioinformatics Research and Applications. 10. (3). p. 235-263.

Kumar, A., Das, S., Purkait, B., Sardar, A.H., Ghosh, A.K., Dikhit, M.R., Abhishek, K., Das, P.(2014). Ascorbate peroxidase, a key molecule regulating amphotericin B resistance in clinical isolates of Leishmania donovani . Antimicrobial Agents and Chemotherapy. 58. (10). p. 6172-6184.

Purkait, B., Singh, R., Wasnik, K., Das, S., Kumar, A., Paine, M., Dikhit, M., Singh, D., Sardar, A.H., Ghosh, A.K., et al.(2014). Up-regulation of silent information regulator 2 (Sir2) is associated with amphotericin B resistance in clinical isolates of Leishmania donovani . Journal of Antimicrobial Chemotherapy. 70. (5). p. 1343-1356.

Sahoo, B.R., Maharana, J., Bhoi, G.K., Lenka, S.K., Patra, M.C., Dikhit, M.R., Dubey, P.K., Pradhan, S.K., Behera, B.K.(2014). A conformational analysis of mouse Nalp3 domain structures by molecular dynamics simulations, and binding site analysis . Molecular BioSystems. 10. (5). p. 1104-1116.

Dikhit, M.R., Moharana, K.C., Sahoo, B.R., Sahoo, G.C., Das, P.(2014). LeishMicrosatDB: open source database of repeat sequences detected in six fully sequenced Leishmania genomes . Database : the journal of biological databases and curation. 2014.

Sahoo, G.C., Ansari, Y., Rana, S., Dikhit, M.R., Topno, R.K., Pandey, K., Das, P.(2014). Molecular modeling and ligand-protein interaction of n-protein of chandipura virus . Letters in Drug Design and Discovery. 11. (2). p. 211-221.

Sahoo BR, Swain B, Dikhit MR, Basu M, Bej A, Jayasankar P, Samanta M, Applied biochemistry and biotechnology, 2013, vol. 170, no. 6, pp. 1282-1309 .

Maharana, J., Swain, B., Sahoo, B.R., Dikhit, M.R., Basu, M., Mahapatra, A.S., Jayasankar, P., Samanta, M.(2013). Identification of MDP (muramyl dipeptide)-binding key domains in NOD2 (nucleotide-binding and oligomerization domain-2) receptor of Labeo rohita . Fish Physiology and Biochemistry. 39. (4). p. 1007-1023.

Sahoo, G.C., Dikhit, M.R., Rani, M., Ansari, M.Y., Jha, C., Rana, S., Das, P.(2013). Analysis of sequence, structure of GAPDH of Leishmania donovani and its interactions . Journal of Biomolecular Structure and Dynamics. 31. (3). p. 258-275.

Kar, R.K., Suryadevara, P., Sahoo, B.R., Sahoo, G.C., Dikhit, M.R., Das, P.(2013). Exploring novel KDR inhibitors based on pharmaco-informatics methodology . SAR and QSAR in Environmental Research. 24. (3). p. 215-234.

Sahoo BR, Basu M, Swain B, Dikhit MR, Jayasankar P, Samanta M, BioMed research international, 2013, vol. 2013, pp. 185282 .

Sahoo, G.C., Ansari, M.Y., Kumar, R., Rani, M., Rana, S., Chauhan, A.S., Dikhit, M.R., Gaurav, K., Ali, V., Sinha, N.K., et al.(2013). Management of treatment and prevention of acute op pesticide poisoning by medical informatics, telemedicine and nanomedicine . International Journal Bioautomation. 17. (3). p. 177-194.

Kar RK, Ansari MY, Suryadevara P, Sahoo BR, Sahoo GC, Dikhit MR, Das P, BioMed research international, 2013, vol. 2013, pp. 609289 .

Kar, R.K., Ansari, M.Y., Suryadevara, P., Sahoo, B.R., Sahoo, G.C., Dikhit, M.R., Das, P.(2013). Computational elucidation of structural basis for ligand binding with Leishmania donovani adenosine kinase . BioMed Research International. 2013.

Sahoo, B.R., Basu, M., Swain, B., Dikhit, M.R., Jayasankar, P., Samanta, M.(2013). Elucidation of novel structural scaffold in rohu TLR2 and its binding site analysis with peptidoglycan, lipoteichoic acid and zymosan ligands, and downstream MyD88 adaptor protein . BioMed Research International. 2013.

Sahoo, G.C., Ansari, M.Y., Dikhit, M.R., Gupta, N., Rana, S., Das, P.(2013). Computational Identification of microRNA-like elements in leishmania major . MicroRNA. 2. (3). p. 225-230.

Sahoo, B.R., Swain, B., Dikhit, M.R., Basu, M., Bej, A., Jayasankar, P., Samanta, M.(2013). Activation of nucleotide-binding oligomerization domain 1 (NOD1) receptor signaling in labeo rohita by ie-dap and identification of ligand-binding key motifs in nod1 by molecular modeling and docking . Applied Biochemistry and Biotechnology. 170. (6). p. 1282-1309.

Ansari, M.Y., Dikhit, M.R., Sahoo, G.C., Das, P.(2012). Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP . International Journal of Biological Macromolecules. 50. (3). p. 637-649.

Kar, R.K., Suryadevara, P., Roushan, R., Sahoo, G.C., Dikhit, M.R., Das, P.(2012). Quantifying the structural requirements for designing newer FLT3 inhibitors . Medicinal Chemistry. 8. (5). p. 913-927.

Rana, S., Dikhit, M.R., Rani, M., Moharana, K.C., Sahoo, G.C., Das, P.(2012). CPDB: Cysteine protease annotation database in Leishmania species . Integrative Biology (United Kingdom). 4. (11). p. 1351-1357.

Sahoo, B.R., Basu, M., Swain, B., Maharana, J., Dikhit, M.R., Jayasankar, P., Samanta, M.(2012). Structural insights of rohu TLR3, its binding site analysis with fish reovirus dsRNA, poly I:C and zebrafish TRIF . International Journal of Biological Macromolecules. 51. (4). p. 531-543.

Bhunia, G.S., Dikhit, M.R., Kesari, S., Sahoo, G.C., Das, P.(2011). Role of remote sensing, geographic bioinformatics system and bioinformatics in kala-azar epidemiology . Journal of Biomedical Research. 25. (6). p. 373-384.

Rani, M., Dikhit, M.R., Sahoo, G.C., Das, P.(2011). Comparative domain modeling of human EGF-like module EMR2 and study of interaction of the fourth domain of EGF with chondroitin 4-sulphate . Journal of Biomedical Research. 25. (2). p. 100-110.

Dikhit MR, Nathasharma YP, Patel L, Rana SP, Sahoo GC, Das P, Bioinformation, 2011, vol. 6, no. 1, pp. 20-22 .

Dikhit MR, Rana SP, Das P, Sahoo GC, Bioinformation, 2009, vol. 3, no. 7, pp. 299-302 .

Sahoo, G.C., Dikhit, M.R., Rani, M., Das, P.(2009). Homology modeling and functional analysis of LPG2 protein of leishmania strains . Journal of Proteomics and Bioinformatics. 2. (1). p. 032-050.

Sahoo GC, Dikhit MR, Das P, Bioinformation, 2008, vol. 3, no. 1, pp. 1-7 .

Manas Ranjan Dikhit, Yangya Prasad Nathasharma, Lelin Patel, Sindhu Prava Rana, Ganesh Chandra Sahoo, Pradeep Das, 2011, 'A comparative protein function analysis database of different Leishmania strains', Bioinformation, vol. 6, no. 1 .

Ganesh Chandra Sahoo, Manas Ranjan Dikhit, Mukta Rani, Md. Yousuf Ansari, Chanda Jha, Sindhuprava Rana, Pradeep Das, 2013, 'Analysis of sequence, structure of GAPDH ofLeishmania donovaniand its interactions', Journal of Biomolecular Structure and Dynamics, vol. 31, no. 3 .

R.K. Kar, P. Suryadevara, B.R. Sahoo, G.C. Sahoo, M.R. Dikhit, P. Das, 2013, 'Exploring novel KDR inhibitors based on pharmaco-informatics methodology', SAR and QSAR in Environmental Research, vol. 24, no. 3 .

Ganesh Chandra Sahoo, Manas Ranjan Dikhit, Pradeep Das, 2008, 'Functional assignment to JEV proteins using SVM', Bioinformation, vol. 3, no. 1 .

Ganesh Chandra Sahoo, Manas Ranjan Dikhit, Mukta Rani, Pradeep Das, 2009, 'Homology Modeling and Functional Analysis of LPG2 Protein of Leishmania Strains', Journal of Proteomics & Bioinformatics, vol. 02, no. 01, pp. 032-050 .

Mukta Rani, Manas R. Dikhit, Ganesh C Sahoo, Pradeep Das, 2011, 'Comparative domain modeling of human EGF-like module EMR2 and study of interaction of the fourth domain of EGF with chondroitin 4-sulphate', Journal of Biomedical Research, vol. 25, no. 2 .