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Hire Dr. Miguel M.

Portugal

USD 90 /hr

Preclinical Scientist & Advisor | Scientific Due Diligence, Electrophysiology & In Vivo Chronic Pain Models

Profile Summary

I am a PhD-trained preclinical scientist with over 10 years of experience in pharmaceutical and biotechnology R&D, specializing in the design, execution, and critical evaluation of preclinical studies. My work focuses on the scientific assessment of preclinical data, with particular expertise in electrophysiology and in vivo chronic pain models (CCI, CFA, CIPN, etc.). I have extensive hands-on experience evaluating study design, endpoints, data robustness, and technical risks that can impact decision-making in early-stage programs. I have acted as Study Director for multiple GLP-compliant toxicology preclinical studies and have managed complex research programs across multidisciplinary teams, combining strong scientific judgment with a quality- and risk-focused mindset. I support biotech teams and investors through focused preclinical due diligence and scientific advisory engagements, helping identify key strengths, data gaps, and preclinical risks.

Subject Matter Expertise

• ☆ Neuroscience
• ☆ Electrophysiology
• ☆ Patch-Clamp Electrophysiology
• ☆ Neurochemistry
• ☆ Drug Development
• ☆ Preclinical Research
• ☆ In vivo Preclinical Toxicology
• ☆ Quality Assurance & Quality Control (QA/QC)

Services

• Research
• Consulting
• Product Development

Research Feasibility Study, Scientific and Technical Research

Consulting Healthcare Consulting, Scientific and Technical Consulting

Product Development Quality Assurance & Control (QA/QC)

Work Experience

Health Project Manager

P-BIO

January 2025 - Present

Head of GLP Services

VectorB2B

January 2024 - January 2025

In vivo Scientist - Study Director

VectorB2B

September 2022 - December 2023

Researcher and Project Manager

Sea4Us

March 2017 - September 2022

Researcher

Universidade Nova de Lisboa

March 2017 - September 2022

Research Assistant

Fundação Champalimaud

July 2016 - December 2016

Research Assistant

Stazione Zoologica Anton Dohrn

February 2011 - August 2011

Education

PhD

Heinrich-Heine-Universitat Düsseldorf

June 2012 - December 2015

Master

Universidade de Lisboa

September 2008 - October 2010

Bachelor

Universidade Nova de Lisboa

September 2004 - July 2008

Certifications

• Project Management

  Rumos

  https://www.credly.com/badges/f15f9d88-ade7-4ff5-acb0-6b355114ff59/linked_in_profile

  July 2025 - Present

Publications

PATENT

Miguel Mondragão (2021). KV1.3 ANTAGONISTS FOR USE IN THE TREATMENT OF CHRONIC AND ACUTE PAIN .

Miguel Mondragão (2021). NITENIN ANALOGUE COMPOUNDS AND THEIR USE IN THE TREATMENT OF CHRONIC AND ACUTE PAIN .

JOURNAL ARTICLE

Gilberto Pereira, Beatriz Szwarc, Miguel A. Mondragão, Pedro A. Lima, Florbela Pereira(2018). A Ligand-Based Approach to the Discovery of Lead-Like Potassium Channel K_V1.3 Inhibitors . ChemistrySelect. 3. (5). p. 1352--1364. Wiley

Gilberto Pereira, Beatriz Szwarc, Miguel A. Mondragão, Pedro A. Lima, Florbela Pereira (2018). A Ligand‐Based Approach to the Discovery of Lead‐Like Potassium Channel KV1.3 Inhibitors . ChemistrySelect.

Mondragão, M.A., Schmidt, H., Kleinhans, C., Langer, J., Kafitz, K.W., Rose, C.R.(2016). Extrusion versus diffusion: mechanisms for recovery from sodium loads in mouse CA1 pyramidal neurons . Journal of Physiology. 594. (19). p. 5507-5527.

Karus, C., Mondragão, M.A., Ziemens, D., Rose, C.R.(2015). Astrocytes restrict discharge duration and neuronal sodium loads during recurrent network activity . GLIA. 63. (6). p. 936-957.