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Profile Details
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Hire Dr. Luca S.

Freelance Computational Drug Discovery Scientist (small molecules/biologics) | Intelligence scouting on AI applications

Profile Summary
Subject Matter Expertise
Writing Technical Writing
Research Market Research, User Research, Gap Analysis, Gray Literature Search, Systematic Literature Review
Consulting Scientific and Technical Consulting
Data & AI Statistical Analysis, Data Visualization, Data Processing
Work Experience


Luca Signorile

January 2021 - Present

Senior Computational Chemist

SOM Biotech

May 2018 - December 2020

Postdoctoral guest scientist

Universität Innsbruck

March 2018 - May 2018

Doctoral Candidate

Erasmus MC

March 2013 - September 2017



Erasmus University Rotterdam

March 2013 - September 2017


Erasmus Medical Center

September 2010 - September 2012


Università degli Studi di Bari

September 2006 - March 2010

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Jo S, Signorile L, Kim S, Kim MS, Huertas O, Insa R, Reig N, Shin DH(2022). A Study of Drug Repurposing to Identify SARS-CoV-2 Main Protease (3CLpro) Inhibitors . International journal of molecular sciences.
Yu N, Signorile L, Basu S, Ottema S, Lebbink JHG, Leslie K, Smal I, Dekkers D, Demmers J, Galjart N(2016). Isolation of Functional Tubulin Dimers and of Tubulin-Associated Proteins from Mammalian Cells . Current biology : CB.
Halim D, Hofstra RM, Signorile L, Verdijk RM, van der Werf CS, Sribudiani Y, Brouwer RW, van IJcken WF, Dahl N, Verheij JB, et al.(2015). ACTG2 variants impair actin polymerization in sporadic Megacystis Microcolon Intestinal Hypoperistalsis Syndrome . Human molecular genetics.
Engelen E, Brandsma JH, Moen MJ, Signorile L, Dekkers DH, Demmers J, Kockx CE, Ozgür Z, van IJcken WF, van den Berg DL, et al.(2015). Proteins that bind regulatory regions identified by histone modification chromatin immunoprecipitations and mass spectrometry . Nature communications.
Narcisi R, Signorile L, Verhaar JA, Giannoni P, van Osch GJ(2012). TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes . Osteoarthritis and cartilage.