Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 200 /hr

★★★★★

☆☆☆☆☆

Hire Lorraine F.

United Kingdom

USD 200 /hr

Consultant in Stable Cell Line Development | GMP Cell Bank Manufacture | Cryopreservation | Biological Sample Management

Profile Summary

20+ years pharma industry experience gained from a variety of R&D roles in early discovery, biological sample management and cell and gene therapy. Offering clients guidance on best practices, optimization, and troubleshooting for stable cell line development, cryopreservation, and biological sample management. Recent experience: Scientific Investigator, Cell and Gene Therapy Product Development, GSK 2019-2023 Worked in cell line development to produce clinical viral vectors from stable producer cell lines. Expertise in Stable vector producer cell line generation and cell line cryopreservation. Technical lead for contracted good manufacturing practice (GMP) cell banking working with third party contract manufacturing organisations (CMOs). Department lead for use of cryogenics, inventory management and safety. Lead Scientist, Biological Asset Management, Discovery Supply, GSK 2005-2019 Key archiving contact for scientists in the UK and Europe. Full operational responsibilities for compliance, training, supervision and managing day to day workload. Prioritized, problem solved and provided continuous support to the team to develop understanding of processes and quality requirements. Expertise in cell & hybridoma culture, cryopreservation & quality control (QC); culture of microbial strains; baculovirus amplification & titration; biological compliance; laboratory inventory management systems (LIMS) and external shipping. Awards: Transformational Medicine Award (2020) Award for an outstanding contribution to R&D. Global Employee Recognition Award – Gold (2020) In recognition of huge commitment to our patients. For demonstrating values & expectations, particularly accountability, teamwork, resilience, and patient focus. Global Employee Recognition Award – Silver (2019) In recognition of your contribution to stable cell line generation in cell and gene therapy. Global Employee Recognition Award – Silver (2019) In recognition of your diligence an HBSM representative that has contributed to GSK’s high level of compliance in HBSM. Recent publications: Johnson S, Mendez-Tavio M, Fellows LA, Cuffaro S, Boiti A and Chen M. Stable Cell Line Generation for Large Scale Lentiviral Vector Manufacture. BioProcess International Europe; Oxford Global Cell UK Conference 2022. Ready SJ, Barto S , Bojczuk K, Clapham C, Fellows LA, Grace J, Haggerson V, Kubik N, Liu Y, Lifely R, Masdin P, Quirin S, Reeves N, Sawhney T, Spaull J, Wallace D and Wysocki L. Building a Centralized, Global, Biological Sample Management Platform in R&D – Challenges and Rewards. ISBER 2016. Fellows LA, Ready SJ, Whittington, JM. Changing Techniques in Biological Archiving. World Biobanking Summit 2009.

Subject Matter Expertise

• ☆ Cell Biology
• ☆ Cell Culture
• ☆ Cell Banking
• ☆ Drug Development

Services

• Writing
• Research
• Consulting

Writing Technical Writing, General Proofreading & Editing

Research Scientific and Technical Research, Systematic Literature Review

Consulting Scientific and Technical Consulting

Work Experience

Scientific investigator, Cell and Gene Therapy Product Development

GlaxoSmithKline

January 2019 - May 2023

Lead Scientist, Biological Asset Management, Discovery Supply

GlaxoSmithKline

September 2005 - July 2019

Senior Scientist, Neuroscience

GlaxoSmithKline

July 1986 - February 1999

Education

BSc (Hons) Pharmacology (2.1)

University of East London

September 1990 - July 1993

Certifications

• 0

  0

  January 2023 - January 2023