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Hire Dr. Levi W.

United States

Principal Scientist in Immunology Seeking Cellular and Immunological Stress Points for Therapeutic Targeting

Profile Summary

Thus far in my career, the primary basis of my research experiences has been in the field of translational immunology and T-cell responses with a concentration on antiviral responses and primary immunodeficiency diseases, particularly ones leading to immunodysregulatory, autoimmune disorders. While at Baylor College of Medicine I was the principal scientist, leading multidisciplinary teams consisting of cell biologists, geneticists, and immunologists, both in basic and clinical sciences in the design of experimentation for the identification and characterization of novel genetic diseases. During my research I made significant discoveries including the identification of COPA syndrome. In recognition of this I was fortunate enough to receive the Lee C. Howley Sr. prize for arthritis research from the arthritis foundation in 2015. I am eager to offer my expertise and expand my experiences beyond academia. I am a life learner and aim to make more contributions to the field.

Subject Matter Expertise

• ★ Immunogenetics
• ☆ Biology/Life Sciences
• ☆ Microbiology
• ☆ Virology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Genetics
• ☆ Basic Immunology
• ☆ Adjuvant & Antigen Research
• ☆ Infectious Disease
• ☆ Viral Diseases
• ☆ Medical Sciences

Services

• Writing
• Research
• Consulting
• Data & AI
• Product Development

Writing Technical Writing

Research Market Research, Feasibility Study, Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Product Development Formulation

Work Experience

Assistant Professor

Baylor College of Medicine

April 2018 - January 2020

Instructor

Baylor College of Medicine

January 2017 - March 2018

Postdoctoral Fellow

Baylor College of Medicine

April 2013 - December 2016

Postdoctoral Associate

University of Massachusetts Medical School

April 2012 - March 2013

Education

PhD

University of Massachusetts Medical School

January 2005 - March 2012

BSc

University of Maine

August 1997 - May 2001

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Aslan, N., Watkin, L.B., Gil, A., Mishra, R., Clark, F.G., Welsh, R.M., Ghersi, D., Luzuriaga, K., Selina, L.K.(2017). Severity of acute infectious mononucleosis correlates with cross-reactive influenza CD8 T-cell receptor repertoires . mBio. 8. (6).

Watkin, L.B., Mishra, R., Gil, A., Aslan, N., Ghersi, D., Luzuriaga, K., Selin, L.K.(2017). Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion . Journal of Allergy and Clinical Immunology. 140. (4). p. 1206-1210.

Mace, E.M., Bigley, V., Gunesch, J.T., Chinn, I.K., Angelo, L.S., Care, M.A., Maisuria, S., Keller, M.D., Togi, S., Watkin, L.B., et al.(2017). Biallelic mutations in IRF8 impair human NK cell maturation and function . Journal of Clinical Investigation. 127. (1). p. 306-320.

Mace, E.M., Bigley, V., Gunesch, J.T., Chinn, I.K., Angelo, L.S., Care, M.A., Maisuria, S., Keller, M.D., Togi, S., Watkin, L.B., et al.(2017). Biallelic mutations in IRF8 impair human NK cell maturation and function . Journal of Clinical Investigation. 127. (1). p. 306-320.

Pedroza, L.A., Guerrero, N., Stray-Pedersen, A., Tafur, C., Macias, R., Muñoz, G., Akdemir, Z.C., Jhangiani, S.N., Watkin, L.B., Chinn, I.K., et al.(2017). First case of CD40LG deficiency in Ecuador, diagnosed after whole exome sequencing in a patient with Severe Cutaneous Histoplasmosis . Frontiers in Pediatrics. 5.

Watkin, L.B., Mishra, R., Gil, A., Aslan, N., Ghersi, D., Luzuriaga, K., Selin, L.K.(2017). Unique influenza A cross-reactive memory CD8 T-cell receptor repertoire has a potential to protect against EBV seroconversion . Journal of Allergy and Clinical Immunology. 140. (4). p. 1206-1210.

Aslan, N., Watkin, L.B., Gil, A., Mishra, R., Clark, F.G., Welsh, R.M., Ghersi, D., Luzuriaga, K., Selina, L.K.(2017). Severity of acute infectious mononucleosis correlates with cross-reactive influenza CD8 T-cell receptor repertoires . mBio. 8. (6).

Pedroza, L.A., Guerrero, N., Stray-Pedersen, A., Tafur, C., Macias, R., Muñoz, G., Akdemir, Z.C., Jhangiani, S.N., Watkin, L.B., Chinn, I.K., et al.(2017). First case of CD40LG deficiency in Ecuador, diagnosed after whole exome sequencing in a patient with Severe Cutaneous Histoplasmosis . Frontiers in Pediatrics. 5.

Lalani, S.R., Liu, P., Rosenfeld, J.A., Watkin, L.B., Chiang, T., Leduc, M.S., Zhu, W., Ding, Y., Pan, S., Vetrini, F., et al.(2016). Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations . American Journal of Human Genetics. 98. (2). p. 347-357.

Vece, T.J., Watkin, L.B., Nicholas, S.K., Canter, D., Braun, M.C., Guillerman, R.P., Eldin, K.W., Bertolet, G., McKinley, S.D., de Guzman, M., et al.(2016). Copa Syndrome: a Novel Autosomal Dominant Immune Dysregulatory Disease . Journal of Clinical Immunology. 36. (4). p. 377-387.

Vece, T.J., Watkin, L.B., Nicholas, S.K., Canter, D., Braun, M.C., Guillerman, R.P., Eldin, K.W., Bertolet, G., McKinley, S.D., de Guzman, M., et al.(2016). Copa Syndrome: a Novel Autosomal Dominant Immune Dysregulatory Disease . Journal of Clinical Immunology. 36. (4). p. 377-387.

Lalani, S.R., Liu, P., Rosenfeld, J.A., Watkin, L.B., Chiang, T., Leduc, M.S., Zhu, W., Ding, Y., Pan, S., Vetrini, F., et al.(2016). Recurrent Muscle Weakness with Rhabdomyolysis, Metabolic Crises, and Cardiac Arrhythmia Due to Bi-allelic TANGO2 Mutations . American Journal of Human Genetics. 98. (2). p. 347-357.

Watkin, L.B., Jessen, B., Wiszniewski, W., Vece, T.J., Jan, M., Sha, Y., Thamsen, M., Santos-Cortez, R.L.P., Lee, K., Gambin, T., et al.(2015). COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis . Nature Genetics. 47. (6). p. 654-660.

Watkin, L.B., Jessen, B., Wiszniewski, W., Vece, T.J., Jan, M., Sha, Y., Thamsen, M., Santos-Cortez, R.L.P., Lee, K., Gambin, T., et al.(2015). COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis . Nature Genetics. 47. (6). p. 654-660.

MacE, E.M., Dongre, P., Hsu, H.-T., Sinha, P., James, A.M., Mann, S.S., Forbes, L.R., Watkin, L.B., Orange, J.S.(2014). Cell biological steps and checkpoints in accessing NK cell cytotoxicity . Immunology and Cell Biology. 92. (3). p. 245-255.

MacE, E.M., Dongre, P., Hsu, H.-T., Sinha, P., James, A.M., Mann, S.S., Forbes, L.R., Watkin, L.B., Orange, J.S.(2014). Cell biological steps and checkpoints in accessing NK cell cytotoxicity . Immunology and Cell Biology. 92. (3). p. 245-255.

Prince, A.L., Watkin, L.B., Yin, C.C., Selin, L.K., Kang, J., Schwartzberg, P.L., Berg, L.J.(2014). Innate PLZF⁺CD4⁺ αβ T cells develop and expand in the absence of itk . Journal of Immunology. 193. (2). p. 673-687.

Gil, A., Kenney, L.L., Mishra, R., Watkin, L.B., Aslan, N., Selin, L.K.(2014). Vaccination and heterologous immunity: Educating the immune system . Transactions of the Royal Society of Tropical Medicine and Hygiene. 109. (1). p. 62-69.

Prince, A.L., Watkin, L.B., Yin, C.C., Selin, L.K., Kang, J., Schwartzberg, P.L., Berg, L.J.(2014). Innate PLZF⁺CD4⁺ αβ T cells develop and expand in the absence of itk . Journal of Immunology. 193. (2). p. 673-687.

Gil, A., Kenney, L.L., Mishra, R., Watkin, L.B., Aslan, N., Selin, L.K.(2014). Vaccination and heterologous immunity: Educating the immune system . Transactions of the Royal Society of Tropical Medicine and Hygiene. 109. (1). p. 62-69.

Cornberg, M., Clute, S.C., Watkin, L.B., Saccoccio, F.M., Kim, S.-K., Naumov, Y.N., Brehm, M.A., Aslan, N., Welsh, R.M., Selin, L.K.(2010). CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections . Journal of Immunology. 184. (6). p. 2825-2838.

Cornberg, M., Clute, S.C., Watkin, L.B., Saccoccio, F.M., Kim, S.-K., Naumov, Y.N., Brehm, M.A., Aslan, N., Welsh, R.M., Selin, L.K.(2010). CD8 T cell cross-reactivity networks mediate heterologous immunity in human EBV and murine vaccinia virus infections . Journal of Immunology. 184. (6). p. 2825-2838.

Clute, S.C., Naumov, Y.N., Watkin, L.B., Aslan, N., Sullivan, J.L., Thorley-Lawson, D.A., Luzuriaga, K., Welsh, R.M., Puzone, R., Celada, F., et al.(2010). Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza a virus epitopes . Journal of Immunology. 185. (11). p. 6753-6764.

Clute, S.C., Naumov, Y.N., Watkin, L.B., Aslan, N., Sullivan, J.L., Thorley-Lawson, D.A., Luzuriaga, K., Welsh, R.M., Puzone, R., Celada, F., et al.(2010). Broad cross-reactive TCR repertoires recognizing dissimilar Epstein-Barr and influenza a virus epitopes . Journal of Immunology. 185. (11). p. 6753-6764.

Towne, C.F., York, I.A., Watkin, L.B., Lazo, J.S., Rock, K.L.(2007). Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses . Journal of Immunology. 178. (11). p. 6923-6930.

Towne, C.F., York, I.A., Watkin, L.B., Lazo, J.S., Rock, K.L.(2007). Analysis of the role of bleomycin hydrolase in antigen presentation and the generation of CD8 T cell responses . Journal of Immunology. 178. (11). p. 6923-6930.

Naumov, Y.N., Naumova, E.N., Clute, S.C., Watkin, L.B., Kota, K., Gorski, J., Selin, L.K.(2006). Complex T cell memory repertoires participate in recall responses at extremes of antigenic load . Journal of Immunology. 177. (3). p. 2006-2014.

Naumov, Y.N., Naumova, E.N., Clute, S.C., Watkin, L.B., Kota, K., Gorski, J., Selin, L.K.(2006). Complex T cell memory repertoires participate in recall responses at extremes of antigenic load . Journal of Immunology. 177. (3). p. 2006-2014.

Clute, S.C., Watkin, L.B., Cornberg, M., Naumov, Y.N., Sullivan, J.L., Luzuriaga, K., Welsh, R.M., Selin, L.K.(2005). Cross-reactive influenza virus-specific CD8⁺ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis . Journal of Clinical Investigation. 115. (12). p. 3602-3612.

Clute, S.C., Watkin, L.B., Cornberg, M., Naumov, Y.N., Sullivan, J.L., Luzuriaga, K., Welsh, R.M., Selin, L.K.(2005). Cross-reactive influenza virus-specific CD8⁺ T cells contribute to lymphoproliferation in Epstein-Barr virus-associated infectious mononucleosis . Journal of Clinical Investigation. 115. (12). p. 3602-3612.