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Hire Dr. Laurie A.

France

USD 180 /hr

PhD in Neurosciences | Expert in Neuroimmunology | 8+ yrs experience | Sci. writing, content creation & data analysis

Profile Summary

A scientist specialized in Neuroscience and Neuroimmunology, I hold a PhD in Neuroscience, where I worked on in vitro models of human pluripotent stem cells (hiPSCs) differentiated into astrocytes in the context of neuroinflammation related to Alzheimer's disease. I have also developed expertise in genome editing using the CRISPR-Cas9 technique (generation of KO and KI clones for APOE). During my postdoctoral mission, I further strengthened my in vivo expertise by working with mouse models, contributing to research that demonstrated the crucial role of meningeal macrophages in neurodevelopment. Throughout this experience, I co-authored scientific articles and reviews and successfully led my own research projects. Passionate about science, literature, and science communication, I am now working as an R&D Project Manager where I also developed expertise in Business Development. I can assist you with various projects, including: -writing and reviewing scientific or medical manuscripts, -grant writing and/or support, -creation of visual materials (presentations, slides), -designing and writing research protocols, -bibliographic research, -scientific illustration, -scientific marketing. My areas of expertise include: Neuroscience, neurodevelopment, neurodegenerative diseases, molecular and cellular biology, and immunology. Scientifique spécialisée en neurosciences et neuro-immunologie, je suis titulaire d’un doctorat en neurosciences durant lequel j’ai travaillé sur des modèles in vitro de cellules souches pluripotentes humaines (hiPSCs), différenciées en astrocytes, dans le cadre de l’étude de la neuroinflammation liée à la maladie d'Alzheimer. J’ai également développé une expertise en édition du génome via la technique CRISPR-Cas9 (génération de clones KO et KI pour l'APOE). Mon expérience postdoctorale m’a permis de renforcer mon expertise in vivo en utilisant des modèles murins. J’ai notamment contribué à démontrer que les macrophages des méninges jouent un rôle crucial dans le neurodéveloppement. Au cours de ces expériences, j’ai participé à la rédaction d’articles scientifiques et de revues, tout en menant à bien mes propres projets de recherche. Passionnée par la science, la littérature et la vulgarisation scientifique, je me consacre désormais à la gestion de projets R&D. Je peux vous accompagner sur de nombreux types de projets, notamment : -l’écriture et la révision de manuscrits scientifiques ou médicaux, -la rédaction et/ou le soutien pour des demandes de bourse, -la création de supports visuels (présentations, diaporamas), -la conception et la rédaction de protocoles de recherche, -la réalisation de bibliographies, -l'illustration scientifique, -le marketing scientifique. Mes domaines d’expertise incluent : neurosciences, neurodéveloppement, maladies neurodégénératives, biologie moléculaire et cellulaire, et immunologie.

Subject Matter Expertise

• ★ Stem Cell Research
• ★ Neuroscience
• ★ Abstracting & Indexing
• ☆ Molecular Biology
• ☆ Biomarkers
• ☆ Genetics
• ☆ Microarrays
• ☆ Omics
• ☆ Transcriptomics
• ☆ Proteomics
• ☆ Genomics
• ☆ PCR
• ☆ Molecular Cloning
• ☆ DNA Sequencing
• ☆ Gene Expression Analysis
• ☆ Mutagenesis
• ☆ Exome Sequencing
• ☆ Recombinant DNA
• ☆ RNA Sequencing
• ☆ Oligonucleotide Synthesis
• ☆ DNA Damage & Repair
• ☆ Cell-Based Assays
• ☆ Cytochemistry
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Gene Regulation
• ☆ Neuroanatomy
• ☆ Developmental Neuroscience
• ☆ Neuropharmacology
• ☆ Molecular Neuroscience
• ☆ Neurobiology
• ☆ Cell Culture
• ☆ Primary Cells
• ☆ Cell Line Engineering
• ☆ 3D Cell Culture
• ☆ Blotting
• ☆ Immunohistochemistry
• ☆ Cytometry
• ☆ Cell Aging
• ☆ Library & Information Science

Services

• Writing

Writing Clinical Trial Documentation, Medical Writing, Non-Medical Regulatory Writing, Technical Writing, Copywriting, Creative Writing

Work Experience

R&D Project Manager

GENXMAP

August 2024 - Present

Centre d'immunologie de Marseille Luminy

November 2021 - October 2024

Aix-Marseille Université

August 2017 - September 2021

Education

PhD | Neuroscience

Aix marseille university

August 2017 - September 2021

Master's degree Neuroscience

Université Grenoble Alpes - France

September 2016 - July 2017

Master's degree in Molecular and Cellular Biology

Université Grenoble Alpes - France

September 2015 - July 2016

Bachelor's degree in Biology

Université Grenoble Alpes - France

September 2013 - May 2015

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Laurie Arnaud Paroutaud, Annie Roussel-Queval, Julie Rebejac, Elisa Eme-Scolan, Rejane Rua(2023). Flow cytometry and immunohistochemistry of the mouse dural meninges for immunological and virological assessments . STAR Protocols. 4. (1). p. 102119. Elsevier {BV}

Laurie Arnaud Paroutaud, Julie Rebejac, Elisa Eme-Scolan, Sarah Kharbouche, Matei Teleman, Lionel Spinelli, Emeline Gallo, Annie Roussel-Queval, Ana Zarubica, Amandine Sansoni, et al.(2022). Meningeal macrophages protect against viral neuroinfection . Immunity. 55. (11). p. 2103--2117.e10. Elsevier {BV}

Laurie Arnaud, Philippe Benech, Louise Greetham, Delphine Stephan, Angélique Jimenez, Nicolas Jullien, Laura García-González, Philipp O. Tsvetkov, François Devred, Ignacio Sancho-Martinez, et al.(2022). APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation . Cell Reports. 40. (7). p. 111200. Elsevier {BV}

Nikita Arnst and Pedro Belio-Mairal and Laura Garc{\'{\i}}a-Gonz{\'{a}}lez and Laurie Arnaud and Louise Greetham and Emmanuel Nivet and Santiago Rivera and Alexander Dityatev(2021). Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes . Cells. 10. (7). p. 1705. {MDPI} {AG}

PREPRINT

Laurie Arnaud and Philippe Benech and Louise Greetham and Delphine Stephan and Ang{\'{e}}lique Jimenez and Nicolas Jullien and Laura Garc{\'{\i}}a-Gonz{\'{a}}lez and Philipp O. Tsvetkov and Fran{\c{c}}ois Devred and Ignacio Sancho-Martinez and Juan-Carlos Izpisua Belmonte and Kevin Baranger and Santiago Rivera and Emmanuel Nivet(2021). The Alzheimer’s disease risk factor APOE4 drives pro-inflammation in human astrocytes via HDAC-dependent repression of TAGLN3 . []. Cold Spring Harbor Laboratory