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USD 50 /hr

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☆☆☆☆☆

Hire Dr. Laurent P.

France

USD 50 /hr

Chemist PhD, Passionnate about organic synthesis. I started my own lab : OpalOrga

Profile Summary

Research, teaching, on-demand synthesis, NMR interpretation, synthesis of small or large series of analogs for SAR, SAR analysis, re-synthesis, retro-synthesis, mechanistic study, experiment plan, optimization, scaling-up, scope and limitations study.

Subject Matter Expertise

• ★ Organic Chemistry
• ★ Drug Discovery
• ★ Medicinal Chemistry
• ☆ Chemical Reagent Development
• ☆ Catalysis
• ☆ Materials Science & Engineering
• ☆ Natural Product Chemistry
• ☆ Supramolecular Chemistry
• ☆ Carbon Materials
• ☆ Green Chemistry
• ☆ Organometallic Chemistry
• ☆ Retrosynthesis
• ☆ Flavor & Fragrance Chemistry
• ☆ Hit-to-Lead & Lead Optimization
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies

Services

• Research

Research Scientific and Technical Research, Systematic Literature Review

Work Experience

chemist

OpalOrga

April 2021 - Present

Education

PhD (Chemistry)

Université Paris Sud (Paris XI) - France

September 2001 - December 2005

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Laurent Pottier, Aminata P. Nacoulma, Moussa Compaoré, Naamwin-so-Bawfu Romaric Meda, Véronique Megalizzi, Issa Some, Martin Kiendrebeogo (2021). Anti-Melanogenesis Effect of Daniellic Acid Isolated from <i>Daniellia oliveri</i> (Rolfe) Hutch. & Dalziel (Leguminosae) Oleoresin of Burkina Faso . Open Journal of Medicinal Chemistry.

Mridul Roy, Long Liang, Xiaojuan Xiao, Peifu Feng, Mao Ye, Jing Liu (2018). Lycorine: A prospective natural lead for anticancer drug discovery . Biomedicine & Pharmacotherapy.

Laurent Pottier, Tsiry Rasamiravaka, Jérémie Ngezahayo, Sofia Ribeiro, Florence Souard, Léonard Hari, Caroline Stévigny, Mondher El Jaziri, Pierre Duez (2017). Terpenoids from Platostoma rotundifolium (Briq.) A. J. Paton Alter the Expression of Quorum Sensing-Related Virulence Factors and the Formation of Biofilm in Pseudomonas aeruginosa PAO1 . International Journal of Molecular Sciences.

Laurent Pottier, Jérémie Ngezahayo, Sofia Oliveira Ribeiro, Cédric Delporte, Véronique Fontaine, Léonard Hari, Caroline Stévigny, Pierre Duez (2016). Plastotoma rotundifolium aerial tissue extract has antibacterial activities . Industrial Crops and Products.

Laurent Pottier, Jérémie Ngezahayo, Sofia Oliveira Ribeiro, Cédric Delporte, Véronique Fontaine, Léonard Hari, Caroline Stévigny, Pierre Duez (2016). Plastotoma rotundifolium aerial tissue extract has antibacterial activities . Industrial Crops and Products.

Laurent Pottier, Jérémie Ngezahayo, Sofia Oliveira Ribeiro, Cédric Delporte, Véronique Fontaine, Léonard Hari, Caroline Stévigny, Pierre Duez (2016). Plastotoma rotundifolium aerial tissue extract has antibacterial activities . Industrial Crops and Products.

Laurent Pottier, Tsiry Rasamiravaka, Olivier M. Vandeputte, Joelle Huet, Christian Rabemanantsoa, Martin Kiendrebeogo, Abel Andriantsimahavandy, Andry Rasamindrakotroka, Caroline Stévigny, Pierre Duez, et al. (2015). Pseudomonas aeruginosa Biofilm Formation and Persistence, along with the Production of Quorum Sensing-Dependent Virulence Factors, Are Disrupted by a Triterpenoid Coumarate Ester Isolated from Dalbergia trichocarpa, a Tropical Legume . PLOS ONE.

Aminata P. Nacoulma, Veronique Megalizzi, Laurent R. Pottier, Manuela De Lorenzi, Sylviane Thoret, Joëlle Dubois, Olivier M. Vandeputte, Pierre Duez, Danny Vereecke, Mondher El Jaziri (2013). Potent Antiproliferative Cembrenoids Accumulate in Tobacco upon Infection with Rhodococcus fascians and Trigger Unusual Microtubule Dynamics in Human Glioblastoma Cells . PLoS ONE.

Laurent Pottier, Delphine Lamoral-Theys, Frédéric Kerff, François Dufrasne, Fabien Proutière, Nathalie Wauthoz, Philippe Neven, Laurent Ingrassia, Pierre Van Antwerpen, Florence Lefranc, et al. (2010). Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli . Bioorganic & Medicinal Chemistry.

D. Lamoral-Theys, L. Pottier, F. Dufrasne, J. Neve, J. Dubois, A. Kornienko, R. Kiss, L. Ingrassia (2010). Natural Polyphenols that Display Anticancer Properties through Inhibition of Kinase Activity . Current Medicinal Chemistry.

D. Lamoral-Theys, C. Decaestecker, V. Mathieu, J. Dubois, A. Kornienko, R. Kiss, A. Evidente, L. Pottier (2010). Lycorine and its Derivatives for Anticancer Drug Design . Mini-Reviews in Medicinal Chemistry.

D. Lamoral-Theys, C. Decaestecker, V. Mathieu, J. Dubois, A. Kornienko, R. Kiss, A. Evidente, L. Pottier (2010). Lycorine and its Derivatives for Anticancer Drug Design . Mini-Reviews in Medicinal Chemistry.

Laurent Pottier, Laurent Ingrassia, Florence Lefranc, Janique Dewelle, V&#233;ronique Mathieu, Sabine Spiegl-Kreinecker, S&#233;bastien Sauvage, Mohamed El Yazidi, Mischa&#235;l Dehoux, Walter Berger, et al. (2009). Structure−Activity Relationship Analysis of Novel Derivatives of Narciclasine (an <i>Amaryllidaceae</i> Isocarbostyril Derivative) as Potential Anticancer Agents . Journal of Medicinal Chemistry.

Laurent Romain Pottier, Jean‐Francois Peyrat, Mouad Alami, Jean‐Daniel Brion (2004). Unexpected Tandem Sonogashira—Carbopallation—Sonogashira Coupling Reaction of Benzyl Halides with Terminal Alkynes: A Novel Four‐Component Domino Sequence to Highly Substituted Enynes . ChemInform.

Laurent Romain Pottier, Jean-Fran&#231;ois Peyrat, Mou&#226;d Alami, Jean-Daniel Brion (2004). Highly substituted enynes via a palladium-catalyzed tandem three carbon–carbon bonds forming reaction procedure from benzyl halides and alkynyl tributyltin reagents . Tetrahedron Letters.