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Profile Details
Subject Matter Expertise
Services
Writing
Medical Writing,
Translation
Work Experience
Researcher
Instituto de Investigação e Inovação em Saúde
June 2024 - Present
Education
PhD
Instituto de Ciências Biomédicas Abel Salazar
January 2020 - May 2024
Master of Science
Universidade de Aveiro
September 2016 - December 2018
Biochemistry (Biochemistry)
Universidade do Porto Faculdade de Ciências
September 2012 - July 2016 
Certifications
- Certification details not provided.
Publications
CONFERENCE ABSTRACT
LAMP2 connects the autophagy-lysosomal pathway in Thymic Epithelial Cells and regulates their role in CD4 T-cell selection, TCR repertoire formation and T-cell responses @inproceedings {
author = {Sousa, Laura and Rodrigues, Pedro M. and Cardoso, João S. and Franquinho, F and Lamas, Sofia and Brites, Pedro and Alves, Nuno L. and Corresponding author: Alves, Nuno L..},
title = {LAMP2 connects the autophagy-lysosomal pathway in Thymic Epithelial Cells and regulates their role in CD4 T-cell selection, TCR repertoire formation and T-cell responses},
address = {Viena},
year = {2025},
month = {aug}
}. 19th International Congress of Immunology (IUIS 2025).
JOURNAL ARTICLE
Camila Ribeiro, Pedro Ferreirinha, Jonathan J. M. Landry, Fátima Macedo, Laura G. Sousa, Rute Pinto, Vladimir Benes, Nuno L. Alves (2024). Foxo3 regulates cortical and medullary thymic epithelial cell homeostasis with implications in T cell development . Cell Death & Disease.
Laura Sousa, Pedro M. Rodrigues, Nuno L. Alves (2023). T cell selection in the thymus: new routes towards the identification of the self‐peptide ligandome presented by thymic epithelial cells . European Journal of Immunology.
Tânia S. C. R. Rebelo, Inês M. Miranda, Ana T. S. C. Brandão, Laura I. G. Sousa, José A. Ribeiro, António F. Silva, Carlos M. Pereira(2021). A Disposable Saliva Electrochemical MIP-Based Biosensor for Detection of the Stress Biomarker α-Amylase in Point-of-Care Applications . Electrochem. 2. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 427--438. {MDPI} {AG}
Tânia S. C. R. Rebelo, Inês M. Miranda, Ana T. S. C. Brandão, Laura I. G. Sousa, José A. Ribeiro, António F. Silva, Carlos M. Pereira (2021). A Disposable Saliva Electrochemical MIP-Based Biosensor for Detection of the Stress Biomarker α-Amylase in Point-of-Care Applications . Electrochem.
CONFERENCE POSTER
The role of KLF15 in the establishment of functional thymic epithelial cell microenvironments @misc {
author = {Sousa, Laura and Ferreirinha, Pedro and Cavadas, Bruno and Alves, Nuno L. and Rodrigues, Pedro M.},
title = {The role of KLF15 in the establishment of functional thymic epithelial cell microenvironments},
year = {2025}
}. L Annual Meeting of the Portuguese Society of Immunology.
Lamp2 connects the autophagy-lysosomal pathway in thymic epithelial cells and regulates CD4 T cell selection, TCR repertoire formation and anti-microbial T cell responses @misc {
author = {Sousa, Laura and Pedro Mendes Rodrigues and Alves, Nuno L.},
title = {Lamp2 connects the autophagy-lysosomal pathway in thymic epithelial cells and regulates CD4 T cell selection, TCR repertoire formation and anti-microbial T cell responses},
year = {2024},
month = {oct}
}. 21st Biennial Meeting of the European Society for Immunodeficiencies.
Development of an in vivo experimental system to study the thymic biology of T-cell leukemia survivors @misc {
author = {Pacheco-Leyva, Ivette and Rodrigues, Pedro M. and Sousa, Laura and Marina C. Baessa and Costa, Telma and Catarino, Telmo A. and Alves, Nuno L. and dos Santos, Nuno R. and Corresponding author: dos Santos, Nuno R..},
title = {Development of an in vivo experimental system to study the thymic biology of T-cell leukemia survivors},
year = {2024},
month = {may}
}. International Meeting ThymE 24: T cell and Thymus Biology, Porto, Portugal.
The molecular program that drives Foxn1 expression is temporally regulated during thymic epithelial cell specification @misc {
author = {Sousa, Laura and Pedro Mendes Rodrigues and Ribeiro, Ana Rita and Jonathan M. Landry and Alves, Nuno L.},
title = {The molecular program that drives Foxn1 expression is temporally regulated during thymic epithelial cell specification},
year = {2024},
month = {may}
}. ThymE: T cell and thymus biology.
Exploring the role of KLF15 in the establishment of the thymic epithelium and its role in T cell education @misc {
author = {Sousa, Laura and Ferreirinha, Pedro and Ribeiro, Ana Rita and Araújo, Leonor and Perrod, Chiara and Landry, Jonathan J. M. and Alves, Nuno L. and Rodrigues, Pedro M. and Corresponding author: Alves, Nuno L..},
title = {Exploring the role of KLF15 in the establishment of the thymic epithelium and its role in T cell education},
year = {2024},
month = {may}
}. ThymE 24: T cell and Thymus Biology.
The molecular program that drives Foxn1 expression is temporally regulated during thymic epithelial cell specification @misc {
author = {Sousa, Laura and Pedro M. Rodrigues and Nuno L. Alves and Jonathan M. Landry},
title = {The molecular program that drives Foxn1 expression is temporally regulated during thymic epithelial cell specification},
year = {2023},
month = {mar}
}. XLVIII Annual Meeting of the Portuguese Society for Immunology.
Lamp-2 expression in cortical thymic epithelial cells fine-tunes CD4/CD8 T cell specification during positive selection @misc {
author = {Perrod, Chiara and Rodrigues, Pedro M. and Cardenas, Gema and Sousa, Laura and Senkara, Meryem and Saftig, Paul and Alves, Nuno L.},
title = {Lamp-2 expression in cortical thymic epithelial cells fine-tunes CD4/CD8 T cell specification during positive selection},
year = {2019},
month = {may}
}. ThymE: T cell and thymus biology.
Lamp-2 expression in cortical thymic epithelial cells fine-tunes CD4/CD8 T cell specification during positive selection @misc {
author = {Perrod, Chiara and Rodrigues, Pedro M. and Cardenas, Gema and Sousa, Laura and Senkara, Meryem and Saftig, Paul and Alves, Nuno L.},
title = {Lamp-2 expression in cortical thymic epithelial cells fine-tunes CD4/CD8 T cell specification during positive selection},
year = {2019},
month = {may}
}. XLV SPI Annual Meeting.
PREPRINT
Laura Sousa, Nuno Alves, Camila Ribeiro, Pedro Ferreirinha, Jonathan Landry, Fátima Macedo, Rute Pinto, Vladimir Benes (2023). Foxo3 Regulates the Homeostasis and Function of Thymic Epithelial Cells .
CONFERENCE PAPER
LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development @inproceedings {
author = {Sousa, Laura},
title = {LAMP2 regulates autophagy in the thymic epithelium and thymic stroma-dependent CD4 T cell development},
year = {2022},
month = {may}
}. Encontro com a Ciência e Tecnologia em Portugal.
BOOK CHAPTER
The Ins and Outs of Thymic Epithelial Cell Differentiation and Function @inbook {
author = {Matsumoto, Minoru and Rodrigues, Pedro M. and Sousa, Laura and Matsumoto, Mitsuru and Alves, Nuno L. and Tsuneyama, Koichi},
title = {The Ins and Outs of Thymic Epithelial Cell Differentiation and Function},
year = {2019}
}. Thymus Transcriptome and Cell Biology.
Ratings and Comments
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