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Profile Details
Hire Dr. Koushik Das-sarma
United Kingdom
Profile Summary
Subject Matter Expertise
Work Experience

University of Essex

October 2018 - Present

Coventry University

October 2018 - Present

Shoolini University

July 2017 - February 2019

Shoolini University

August 2013 - February 2019


Jubilant Chemsys Limited

July 2011 - May 2014

Assistant Director

Nycomed Pharma Private Ltd

December 2008 - July 2011

Group Leader

Advinus Therapeutics Ltd Pune

July 2006 - November 2008

Postdoctoral Fellow

Pfizer Global Research and Development

October 2004 - July 2006

Postdoctoral Fellow

Duke University

April 2002 - September 2004

Postdoctoral Fellow

Purdue University

April 2001 - April 2002

R&D Manager

RL Fine Chem

August 2000 - February 2001


PhD (Essex Business School)

University of Essex

October 2018 - Present

PhD (Organic Chemistry)

Indian Institute of Science

- March 2000

MS (Chemistry)

Indian Institute of Science

- July 1995

  • Certification details not provided.
Biswas, Kallolmay and Gholap, Rajesh and Srinivas, Padakanti and Kanyal, Sachin and Sarma, Koushik Das(2014). β-Substituted γ-butyrolactams from mucochloric acid: synthesis of (±)-baclofen and other γ-aminobutyric acids and useful building blocks. RSC Advances. 4. (5). p. 2538--2545. Royal Society of Chemistry
Gopinath, Vadiraj S and Rao, Mukkavilli and Shivahare, Rahul and Vishwakarma, Preeti and Ghose, Sweta and Pradhan, Ashok and Hindupur, Ramamohan and Sarma, Koushik Das and Gupta, Suman and Puri, Sunil K and others(2014). Design, synthesis, ADME characterization and antileishmanial evaluation of novel substituted quinoline analogs. Bioorganic & medicinal chemistry letters. 24. (9). p. 2046--2052. Elsevier
Biswas, Kallolmay and Kumar, Arvind and Das Sarma, Koushik(2013). One-Pot High-Throughput Synthesis of a 160-Membered Library of Methyl 3,5-Diaryl-isoxazoline-5-carboxylate Pharmacophores by a 2˙2˙2-Component Reaction. ACS Combinatorial Science. 15. p. 255--260. American Chemical Society
Zhang, Ji and Sarma, Koushik Das and Curran, Timothy T(2013). Recent Progress in the Chemistry of Mucohalic Acids: Versatile Building Blocks in Organic Synthesis. Synlett. 24. (05). p. 550--569. {\copyright} Georg Thieme Verlag
Basu, Sujay and Prasad, Uppuleti Viplava and Barawkar, Dinesh A and De, Siddhartha and Palle, Venkata P and Menon, Suraj and Patel, Meena and Thorat, Sachin and Singh, Umesh P and Sarma, Koushik Das and others(2012). Discovery of novel and potent heterocyclic carboxylic acid derivatives as protein tyrosine phosphatase 1B inhibitors. Bioorganic & medicinal chemistry letters. 22. (8). p. 2843--2849. Elsevier
Thur, Yithachu and Bhalerao, Amit and Munshi, Zaki and Pansare, Nisha and Mann, Klaus and Hanauer, Guido and Kley, Hans-Peter and Nappe, Sandra and Weiss-Haljiti, Cornelia and Ostermann, Claude and others(2012). Structure--activity relationships of 2-arylamido-5, 7-dihydro-4H-thieno [2, 3-c] pyran-3-carboxamide derivatives as cannabinoid receptor agonists and their analgesic action. Bioorganic & medicinal chemistry letters. 22. (24). p. 7314--7321. Elsevier
Khan, Md Abdul Shafeeuulla and Zhang, Ji and Sarma, Koushik Das and Ganguly, Bishwajit(2012). Origins of reversing diastereoselectivity of α, β-dichloro-γ-butenolides and γ-butyrolactams in direct vinylogous aldol addition: a computational study. RSC Advances. 2. (22). p. 8460--8466. Royal Society of Chemistry
Pirrung, Michael C and Sarma, Koushik Das and Wang, Jianmei(2008). Hydrophobicity and mixing effects on select heterogeneous, water-accelerated synthetic reactions. The Journal of organic chemistry. 73. (22). p. 8723--8730. ACS Publications
Das Sarma, Koushik and Zhang, Ji and Curran, Timothy T(2007). Novel synthons from mucochloric acid: The first use of α, β-dichloro-γ-butenolides and γ-butyrolactams for direct vinylogous aldol addition. The Journal of organic chemistry. 72. (9). p. 3311--3318. ACS Publications
Das Sarma, Koushik and Zhang, Ji and Huang, Yun and Davidson, James G(2006). Amino Acid Esters and Amides for Reductive Amination of Mucochloric Acid: Synthesis of Novel γ-Lactams, Short Peptides and Antiseizure Agent Levetiracetam (Keppra®). European journal of organic chemistry. 2006. (16). p. 3730--3737. Wiley Online Library
Pirrung, Michael C and Sarma, Koushik Das(2005). Aqueous medium effects on multi-component reactions. Tetrahedron. 61. (48). p. 11456--11472. Elsevier
Zhang, Ji and Sarma, Koushik Das and Curran, Timothy T(2005). Efficient formation of novel and versatile building blocks from mucohalic acids: new substitute for tetronic acid and $γ$-alkylidenebutenolide. Tetrahedron letters. 46. (38). p. 6433--6436. Elsevier
Pirrung, Michael C and Pansare, Sunil V and Sarma, Koushik Das and Keith, Kathy A and Kern, Earl R(2005). Combinatorial optimization of isatin-β-thiosemicarbazones as anti-poxvirus agents. Journal of medicinal chemistry. 48. (8). p. 3045--3050. ACS Publications
Zhang, Ji and Sarma, Koushik Das and Curran, Timothy T and Belmont, Daniel T and Davidson, James G(2005). Efficient synthesis of novel $γ$-substituted $γ$-butenolides by Lewis acid catalyzed addition of metal enolates of active methylene compounds to mucohalic acids. The Journal of organic chemistry. 70. (15). p. 5890--5895. ACS Publications
Pirrung, Michael C and Sarma, Koushik Das(2004). Multicomponent reactions are accelerated in water. Journal of the American Chemical Society. 126. (2). p. 444--445. ACS Publications
Pirrung, Michael C and Sarma, Koushik Das(2004). β-Lactam synthesis by Ugi reaction of β-keto acids in aqueous solution. Synlett. 2004. (08). p. 1425--1427. {\copyright} Georg Thieme Verlag Stuttgart{\textperiodcentered} New York
Sarma, Koushik Das and Maitra, Uday(2001). Aqueous organotin chemistry: Part 3-triphenyltin hydride and di-n-butyltin dichloride mediated nucleophilic substitution of 2-iodobenzoates in water. Indian Journal of Chemistry Section B. 40. (11). p. 1148--1150. PUBLICATIONS \& INFORMATION DIRECTORATE, CSIR
Ray, Dipankar and Sarma, Koushik Das and Antony, Abraham(2000). Differential Effects of Tri-n-Butylstannyl Benzoates on Induction of Apoptosis in K562 and MCF-7 Cells. IUBMB life. 49. (6). p. 519--525. Wiley Online Library
Sarma, KD and Ray, D and Antony, A(2000). Improved sensitivity of trypan blue dye exclusion assay with Ni2+ or Co2+ salts. Cytotechnology. 32. (2). p. 93--95. Springer
Ranganathan, Darshan and Thomas, A and Haridas, V and Kurur, S and Madhusudanan, KP and Roy, Raja and Kunwar, AC and Sarma, AVS and Vairamani, M and Sarma, KD(1999). Design, synthesis, and characterization of tyrosinophanes, a novel family of aromatic-bridged tyrosine-based cyclodepsipeptides. The Journal of organic chemistry. 64. (10). p. 3620--3629. ACS Publications
Sarma, Koushik Das and Maitra, Uday(1998). Aqueous organotin chemistry: Tin hydride mediated dehalogenation of organohalides and a novel organotin mediated nucleophilic substitution on 2-iodobenzoates in water. Tetrahedron. 54. (19). p. 4965--4976. Elsevier
Maitra, Uday and Sarma, Koushik Das(1994). Tri-n-butylin hydride mediated dehalogenation in water. Tetrahedron letters. 35. (42). p. 7861--7862. Elsevier
Zhang, J and Das Sarma, K and Blazecka, PG and Angell, P and Curran, TT and Belmont, D and Davidson, JG(2005). Further utilization of mucohalic acids in Lewis acid-catalyzed Knoevenagelaldol and Friedel-Crafts reactions. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. 230. p. U3319--U3320.