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Hire Dr. Kiranam C.

India

USD 35 /hr

Research Scientist and BELS-certified Editor with 10+ years of experience in the Life Sciences

Profile Summary

I am a scientist with thirteen years of post-PhD laboratory research experience. I am also a BELS-certified editor, and serve on the editorial board of the Elsevier Journal Heliyon. My main areas of work have been tyrosine kinase regulation and diversity in cancer, and using the zebrafish as a model organism. I have expertise in molecular biology, biochemistry, pharmacology and bioinformatics.

Subject Matter Expertise

• ☆ Biostatistics
• ☆ Kinases
• ☆ Biotechnology & Bioengineering
• ☆ Bioinformatics
• ☆ Protein/Enzyme Engineering
• ☆ Oncology
• ☆ Technical & Scientific Writing

Services

• Writing
• Research
• Data & AI

Writing Technical Writing, Newswriting

Research Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Data & AI Statistical Analysis

Work Experience

Principal Research Scientist

Dr Reddy's Institute of Life Sciences

2013 - 2015

Senior Research Scientist

Dr Reddy's Institute of Life Sciences

2008 - 2013

Post-Doctoral Research Associate

Stony Brook University

2005 - 2008

Education

Certified Editor in the Life Sciences

Board of Editors in the Life Sciences

March 2017 - Present

BELS Editor Certification

Board of Editors in the Life Sciences

February 2017 - Present

Ph.D. (Pharmacology and Toxicology)

University of Mississippi Medical Center

1998 - 2004

Junior Research Fellow

Centre for Cellular and Molecular Biology CSIR

1997 - 1998

M.Sc. (Biotechnology)

Madurai Kamaraj University

1995 - 1997

B.Sc. (Genetics, Chemistry, Botany)

Nizam College

1992 - 1995

Certifications

• BELS-Certified Editor

  Board of Editors in the Life Sciences

  December 2017 - December 2026

Publications

JOURNAL ARTICLE

Kiranam Chatti, Samantha D. Foster, Sarah R. Glover, Ashley N. Turner, Anil K. Challa(2019). A mixing heteroduplex mobility assay (mHMA) to genotype homozygous mutants with small indels generated by CRISPR-Cas9 nucleases . MethodsX. 6. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--5. Elsevier {BV}

Bhanushali, Umesh and Rajendran, Saranya and Sarma, Keerthana and Kulkarni, Pushkar and Chatti, Kiranam and Chatterjee, Suvro and Ramaa, C. S.(2016). 5-Benzylidene-2,4-thiazolidenedione derivatives: Design, synthesis and evaluation as inhibitors of angiogenesis targeting VEGR-2 . Bioorganic Chemistry. 67. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 139--147.

Vemula, Mani H. and Medisetti, Raghavender and Ganji, Rakesh and Jakkala, Kiran and Sankati, Swetha and Chatti, Kiranam and Banerjee, Sharmistha(2016). Mycobacterium tuberculosis zinc metalloprotease-1 assists mycobacterial dissemination in zebrafish . Frontiers in Microbiology. 7. (AUG).

Kulkarni, Pushkar and Chaudhari, Girish Hari and Sripuram, Vijaykumar and Banote, Rakesh Kumar and Kirla, Krishna Tulasi and Sultana, Razia and Rao, Pallavi and Oruganti, Srinivas and Chatti, Kiranam(2014). Oral dosing in adult zebrafish: Proof-of-concept using pharmacokinetics and pharmacological evaluation of carbamazepine . Pharmacological Reports. 66. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 179--183.

Kulkarni, P., Chaudhari, G.H., Sripuram, V., Banote, R.K., Kirla, K.T., Sultana, R., Rao, P., Oruganti, S., Chatti, K.(2014). Oral dosing in adult zebrafish: Proof-of-concept using pharmacokinetics and pharmacological evaluation of carbamazepine . Pharmacological Reports. 66. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 179-183.

Banote, Rakesh Kumar and Koutarapu, Srinivas and Chennubhotla, Keerthana Sarma and Chatti, Kiranam and Kulkarni, Pushkar(2013). Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish . Epilepsy & behavior : E&B. 27. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 212--219.

Challa, Anil Kumar and Chatti, Kiranam(2013). Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology . Zebrafish. 10. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 264--274.

Challa, A.K., Chatti, K.(2013). Conservation and early expression of zebrafish tyrosine kinases support the utility of zebrafish as a model for tyrosine kinase biology . Zebrafish. 10. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 264-274.

Babu, P. Vijaya and Mukherjee, Soumita and Deora, Girdhar Singh and Chennubhotla, Keerthana Sarma and Medisetti, Raghavender and Yellanki, Swapna and Kulkarni, Pushkar and Sripelly, Shivashankar and Parsa, Kishore V. L. and Chatti, Kiranam and Mukkanti, K. and Pal, Manojit(2013). Ligand/PTC-free intramolecular Heck reaction: synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo . Organic & Biomolecular Chemistry. 11. (39). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6680.

Babu, P.V., Mukherjee, S., Deora, G.S., Chennubhotla, K.S., Medisetti, R., Yellanki, S., Kulkarni, P., Sripelly, S., Parsa, K.V.L., Chatti, K., et al.(2013). Ligand/PTC-free intramolecular Heck reaction: Synthesis of pyrroloquinoxalines and their evaluation against PDE4/luciferase/oral cancer cell growth in vitro and zebrafish in vivo . Organic and Biomolecular Chemistry. 11. (39). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6680-6685.

Chaudhari, G.H., Chennubhotla, K.S., Chatti, K., Kulkarni, P.(2013). Optimization of the adult zebrafish ECG method for assessment of drug-induced QTc prolongation . Journal of Pharmacological and Toxicological Methods. 67. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 115-120.

Chaudhari, Girish Hari and Chennubhotla, Keerthana Sarma and Chatti, Kiranam and Kulkarni, Pushkar(2013). Optimization of the adult zebrafish ECG method for assessment of drug-induced QTc prolongation . Journal of Pharmacological and Toxicological Methods. 67. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 115--120.

Banote, R.K., Koutarapu, S., Chennubhotla, K.S., Chatti, K., Kulkarni, P.(2013). Oral gabapentin suppresses pentylenetetrazole-induced seizure-like behavior and cephalic field potential in adult zebrafish . Epilepsy \& behavior : E\&B. 27. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 212-219.

Dulla, Balakrishna and Kirla, Krishna Tulasi and Rathore, Vandana and Deora, Girdhar Singh and Kavela, Sridhar and Maddika, Subbareddy and Chatti, Kiranam and Reiser, Oliver and Iqbal, Javed and Pal, Manojit(2013). Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties . Organic & Biomolecular Chemistry. 11. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3103.

Dulla, B., Kirla, K.T., Rathore, V., Deora, G.S., Kavela, S., Maddika, S., Chatti, K., Reiser, O., Iqbal, J., Pal, M.(2013). Synthesis and evaluation of 3-amino/guanidine substituted phenyl oxazoles as a novel class of LSD1 inhibitors with anti-proliferative properties . Organic and Biomolecular Chemistry. 11. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3103-3107.

Reddy, E. Ramanjaneya and Banote, Rakesh Kumar and Chatti, Kiranam and Kulkarni, Pushkar and Rajadurai, Marina S.(2012). Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles . ChemBioChem. 13. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1889--1894.

Reddy, E Ramanjaneya and Banote, Rakesh Kumar and Chatti, Kiranam and Kulkarni, Pushkar and Rajadurai, Marina S(2012). Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles . Chembiochem : a European journal of chemical biology. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1--6.

Kumar, K.S., Rambabu, D., Sandra, S., Kapavarapu, R., Krishna, G.R., Basaveswara Rao, M.V., Chatti, K., Reddy, C.M., Misra, P., Pal, M.(2012). AlCl 3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents . Bioorganic and Medicinal Chemistry. 20. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1711-1722.

Reddy, E.R., Banote, R.K., Chatti, K., Kulkarni, P., Rajadurai, M.S.(2012). Selective Multicolour Imaging of Zebrafish Muscle Fibres by Using Fluorescent Organic Nanoparticles . ChemBioChem. 13. (13). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1889-1894.

Kumar, K. Shiva and Rambabu, D. and Sandra, Sandhya and Kapavarapu, Ravikumar and Krishna, G. Rama and {Basaveswara Rao}, M. V. and Chatti, Kiranam and Reddy, C. Malla and Misra, Parimal and Pal, Manojit(2012). AlCl 3 induced (hetero)arylation of 2,3-dichloroquinoxaline: A one-pot synthesis of mono/disubstituted quinoxalines as potential antitubercular agents . Bioorganic and Medicinal Chemistry. 20. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1711--1722.

Rana, N., Moond, M., Marthi, A., Bapatla, S., Sarvepalli, T., Chatti, K., Challa, A.K.(2010). Caffeine-induced effects on heart rate in zebrafish embryos and possible mechanisms of action: An effective system for experiments in chemical biology . Zebrafish. 7. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 69-81.

Rana, Neha and Moond, Mamta and Marthi, Amarnath and Bapatla, Swetha and Sarvepalli, Tejasudha and Chatti, Kiranam and Challa, Anil Kumar(2010). Caffeine-Induced Effects on Heart Rate in Zebrafish Embryos and Possible Mechanisms of Action: An Effective System for Experiments in Chemical Biology . Zebrafish. 7. (1). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 69--81.

Xiang, Bin and Chatti, Kiranam and Qiu, Haoqun and Lakshmi, B and Krasnitz, Alexander and Hicks, Jim and Yu, Min and Miller, W Todd and Muthuswamy, Senthil K(2008). Brk is coamplified with ErbB2 to promote proliferation in breast cancer . Proceedings of the National Academy of Sciences of the United States of America. 105. (34). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12463--12468.

Xiang, B., Chatti, K., Qiu, H., Lakshmi, B., Krasnitz, A., Hicks, J., Yu, M., Miller, W.T., Muthuswamy, S.K.(2008). Brk is coamplified with ErbB2 to promote proliferation in breast cancer . Proceedings of the National Academy of Sciences of the United States of America. 105. (34). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 12463-12468.

Mamoon, Naila M. and Smith, John K. and Chatti, Kiranam and Lee, Sheeyong and Kundrapu, Kanakadurga and Duh\'{e}, Roy J.(2007). Multiple cysteine residues are implicated in Janus kinase 2-mediated catalysis . Biochemistry. 46. (51). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 14810--14818.

Mamoon, N.M., Smith, J.K., Chatti, K., Lee, S., Kundrapu, K., Duhé, R.J.(2007). Multiple cysteine residues are implicated in Janus kinase 2-mediated catalysis . Biochemistry. 46. (51). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 14810-14818.

Chatti, K., Farrar, W.L., Duhé, R.J.(2004). Tyrosine Phosphorylation of the Janus Kinase 2 Activation Loop Is Essential for a High-Activity Catalytic State but Dispensable for a Basal Catalytic State . Biochemistry. 43. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4272-4283.

Chatti, Kiranam and Farrar, William L. and Duh\'{e}, Roy J.(2004). Tyrosine Phosphorylation of the Janus Kinase 2 Activation Loop Is Essential for a High-Activity Catalytic State but Dispensable for a Basal Catalytic State . Biochemistry. 43. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 4272--4283.

OTHER

Krishna, Syam and Chatti, Kiranam and Galigekere, Ramesh R.(2017). Automatic and Robust Estimation of Heart Rate in Zebrafish Larvae . IEEE Transactions on Automation Science and Engineering.

CONFERENCE PAPER

Krisna, Syam and Chatti, Kiranam and Mestha, Lalit K. and Galigekere, Ramesh R.(2013). Algorithms for automatic & non-contact assessment of the cardiovascular system in zebrafish larvae . IEEE EMBS Special Topic Conference on Point-of-Care (POC) Healthcare Technologies: Synergy Towards Better Global Healthcare, PHT 2013. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 46--49.

Krisna, S., Chatti, K., Mestha, L.K., Galigekere, R.R.(2013). Algorithms for automatic & non-contact assessment of the cardiovascular system in zebrafish larvae . IEEE EMBS Special Topic Conference on Point-of-Care (POC) Healthcare Technologies: Synergy Towards Better Global Healthcare, PHT 2013. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 46-49.