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Hire Dr. Kenneth E.

United Kingdom

USD 10 /hr

30+ years in life sciences research, freelance science editor and writer

Profile Summary

I am a successful medical researcher in the areas of cancer, 3D organoid culture, oncogenic drug discovery, cell signalling pathways and developmental biology. Of 21 papers that I am an author on, I substantially wrote 11 and also a book chapter. I have written numerous conference abstracts and prepared many posters.

Subject Matter Expertise

• ★ Cell Signaling Pathways
• ☆ Developmental Biology
• ☆ Cell Biology
• ☆ Stem Cell Research
• ☆ Cell Culture
• ☆ Drug Development

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, Copywriting, Newswriting

Research Market Research, Feasibility Study, Fact Checking, Gray Literature Search, Systematic Literature Review, Secondary Data Collection

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Work Experience

Research Associate

Cardiff University

January 2004 - October 2020

Postdoctoral Fellow

E O Lawrence Berkeley National Laboratory

January 1999 - June 2003

Postdoctoral Fellow

Max-Planck-Institut für biophysikalische Chemie

June 1996 - December 1998

Scientific Officer

University of Sydney

April 1995 - May 1996

Research Assistant

University of Sydney

June 1988 - December 1990

Technical Officer

Concord Repatriation General Hospital

June 1987 - June 1988

Education

PhD (Physiology)

University of Western Australia

1991 - 1995

BSc (Biochemistry)

University of Sydney

1983 - 1987

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Rodrigo M Young, Kenneth B Ewan, Veronica P Ferrer, Miguel L Allende, Jasminka Godovac-Zimmermann, Trevor C Dale, Stephen W Wilson(2019). Developmentally regulated Tcf7l2 splice variants mediate transcriptional repressor functions during eye formation . {eLife}. 8. {eLife} Sciences Publications, Ltd

(2017). Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling that Targets β-Catenin Protein-Protein Interactions . Cell Chemical Biology.

(2016). Assessing the mechanism and therapeutic potential of modulators of the human Mediator complex-associated protein kinases . eLife.

(2016). Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids . Nature Communications.

(2015). A selective chemical probe for exploring the role of CDK8 and CDK19 in human disease . Nature Chemical Biology.

(2015). A functional connectome: regulation of Wnt/TCF-dependent transcription by pairs of pathway activators . Molecular Cancer.

Ewan, K., Paja̧k, B., Stubbs, M., Todd, H., Barbeau, O., Quevedo, C., Botfield, H., Young, R., Ruddle, R., Samuel, L., et al.(2010). A useful approach to identify novel small-molecule inhibitors of Wnt-dependent transcription . Cancer Research. 70. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5963-5973.

Phesse, T.J., Parry, L., Reed, K.R., Ewan, K.B., Dale, T.C., Sansom, O.J., Clarke, A.R.(2008). Deficiency of Mbd2 attenuates Wnt signaling . Molecular and Cellular Biology. 28. (19). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 6094-6103.

Ewan, K.B.R., Dale, T.C.(2008). The potential for targeting oncogenic WNT/β-catenin signaling in therapy . Current Drug Targets. 9. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 532-547.

Shimshoni, J.A., Dalton, E.C., Jenkins, A., Eyal, S., Ewan, K., Williams, R.S.B., Pessah, N., Yagen, B., Harwood, A.J., Bialer, M.(2007). The effects of central nervous system-active valproic acid constitutional isomers, cyclopropyl analogs, and amide derivatives on neuronal growth cone behavior . Molecular Pharmacology. 71. (3). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 884-892.

Smalley, M.J., Signoret, N., Robertson, D., Tilley, A., Hann, A., Ewan, K., Ding, Y., Paterson, H., Dale, T.C.(2005). Dishevelled (Dvl-2) activates canonical Wnt signalling in the absence of cytoplasmic puncta . Journal of Cell Science. 118. (22). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5279-5289.

Ewan, K.B.R., Oketch-Rabah, H.A., Ravani, S.A., Shyamala, G., Moses, H.L., Barcellos-Hoff, M.H.(2005). Proliferation of estrogen receptor-α-positive mammary epithelial cells is restrained by transforming growth factor-β1 in adult mice . American Journal of Pathology. 167. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 409-417.

Ewan, K.B., Henshall-Powell, R.L., Ravani, S.A., Pajares, M.J., Arteaga, C., Warters, R., Akhurst, R.J., Barcellos-Hoff, M.H.(2002). Transforming growth factor-β1 mediates cellular response to DNA damage in situ . Cancer Research. 62. (20). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 5627-5631.

Ewan, K.B., Shyamala, G., Ravani, S.A., Tang, Y., Akhurst, R., Wakefield, L., Barcellos-Hoff, M.H.(2002). Latent transforming growth factor-β activation in mammary gland: Regulation by ovarian hormones affects ductal and alveolar proliferation . American Journal of Pathology. 160. (6). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 2081-2093.

Barcellos-Hoff, M.H., Ewan, K.B.R.(2000). Transforming growth factor-β and breast cancer: Mammary gland development . Breast Cancer Research. 2. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 92-99.

Jean, D., Ewan, K., Gruss, P.(1998). Molecular regulators involved in vertebrate eye development . Mechanisms of Development. 76. (1-2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3-18.

Pamphlett, R., Ewan, K.B.R., McQuilty, R., Waley, P.(1997). Gender differences in the uptake of inorganic mercury by motor neurons . Neurotoxicology and Teratology. 19. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 287-293.

Ewan, K.B.R., Everett, A.W.(1996). A quantitative study of the segmental distribution of somitic cells in the developing chick limb bud using laser-scanning confocal microscopy . Journal of Histochemistry and Cytochemistry. 44. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 347-355.

Ewan, K.B.R., Pamphlett, R.(1996). Increased inorganic mercury in spinal motor neurons following chelating agents . NeuroToxicology. 17. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 343-350.

Ewan, K.B.R., Everett, A.W.(1992). Evidence for resegmentation in the formation of the vertebral column using the novel approach of retroviral-mediated gene transfer . Experimental Cell Research. 198. (2). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 315-320.

OTHER

Rodrigo M. Young, Kenneth B. Ewan, Veronica P. Ferrer, Miguel L. Allende, Jasminka Godovac-Zimmermann, Trevor C. Dale, Stephen W. Wilson(2019). Developmentally regulated tcf7l2 splice variants mediate transcriptional repressor functions during eye formation . Cold Spring Harbor Laboratory