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USD 65 /hr

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Hire Dr. Kayoko S.

Norway

USD 65 /hr

PhD Biomedical Engineer | Organ-on-Chip & Biosensors | Scientific Figures, Writing & EN-JP

Profile Summary

PhD biomedical engineer (University of Tokyo) with 15+ years of research and R&D experience in microfluidics, organ-on-chip (OoC) / microphysiological systems (MPS), biosensors, and medical device development. Background bridges academic research and applied engineering, with peer-reviewed publications and granted patents in the field. Research expertise: - Microfluidic device design and fabrication (PDMS, soft lithography, CAD-based mold design) - Engineered cell-encapsulating hydrogel systems (hollow collagen microgel beads, Biomicrofluidics) - Immunology and clinical sample workflows (former: Oslo University Hospital, Dept. of Immunology / Krauss group) - Biosensor and point-of-care diagnostic concepts Services offered: - Experimental design and protocol consultation for microfluidics, OoC, and biosensor projects - Scientific writing: original research, reviews, grant proposals, technical white papers - Manuscript review and peer-review support - Japanese-English scientific translation and bilingual editing (native Japanese speaker, academic English) - CAD-based scientific figures and device schematics (Fusion 360, SolidEdge, Blender) Published as Hirayama-Shoji, K. Based in Oslo, Norway. Available for remote projects across time zones.

Subject Matter Expertise

• ★ Tissue Engineering
• ☆ Cell Biology
• ☆ Biotechnology & Bioengineering
• ☆ Biomedical Engineering
• ☆ Microfluidics
• ☆ Cell Culture
• ☆ 3D Cell Culture
• ☆ Peer Review
• ☆ Technical & Scientific Writing
• ☆ Manuscript & Journal Article Writing
• ☆ Experimental Protocols
• ☆ SOP & Protocol Writing
• ☆ Grant Writing

Services

• Writing
• Research
• Consulting

Writing Technical Writing

Research Scientific and Technical Research

Consulting Scientific and Technical Consulting

Work Experience

Postdoctoral Fellow / Researcher

Oslo University Hospital

September 2022 - December 2023

Postdoctoral Fellow / Researcher

University of Oslo / Oslo University Hospital

September 2019 - December 2023

Postdoctoral Fellow / Researcher

University of Oslo

September 2019 - August 2022

Principal Researcher

CellFiber Co., Ltd.

October 2017 - September 2019

Principal Researcher

CellFiber Co., Ltd.

October 2013 - September 2019

Postdoctoral Researcher

The University of Tokyo

April 2013 - April 2019

Postdoctoral Researcher

The University of Tokyo

2013 - 2019

Education

Ph.D. in Biomedical Engineering (Takeuchi Laboratory)

The University of Tokyo

2010 - 2013

M.Sc. in Biotechnology (Graduate School of Agricultural and Life Sciences, Department of Biotechnology)

The University of Tokyo

2008 - 2010

B.Sc. in Biotechnology (Faculty of Agriculture, Department of Biotechnology)

The University of Tokyo

2003 - 2007

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Nøvik, S., Hirayama-Shoji, K., others(2025). Bioimpedance and electrophysiology measurements of engineered heart tissues. Biosensors and Bioelectronics. 287.

Ikegami, R., Tsukagoshi, T., Matsudaira, K., Shoji, K. H., Takahashi, H., Nguyen, T.-V., Tamamoto, T., Noda, K., Koyanagi, K., Oshima, T., et al.(2023). Temperature dependence of the beating frequency of hiPSC-CMs using a MEMS force sensor. Sensors. 23. (7). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3370.

Vazquez, P., Hirayama-Shoji, K., Novik, S., Krauss, S., Rayner, S.(2022). Globally Accessible Distributed Data Sharing (GADDS): a decentralized FAIR platform to facilitate data sharing in the life sciences. Bioinformatics. 38. (15). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 3812--3817.

Matsudaira, K., Takahashi, H., Hirayama-Shoji, K., Tsukagoshi, T., Nguyen, T.-V., Shimoyama, I.(2021). Isometric contraction force measurement of hiPSC-CMs on a movable plate with a feedback-controlled MEMS cantilever probe. Measurement Science and Technology. 32. (11). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 115118.

Abadpour, S., Aizenshtadt, A., Olsen, P. A., Shoji, K., Wilson, S. R., Krauss, S., Scholz, H.(2020). Pancreas-on-a-chip technology for transplantation applications. Current Diabetes Reports. 20. (12). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 72.

Matsudaira, K., Takahashi, H., Hirayama-Shoji, K., Nguyen, T.-V., Tsukagoshi, T., Shimoyama, I.(2019). A MEMS-based measurement system for evaluating the force--length relationship of human induced pluripotent stem cell-derived cardiomyocytes adhered on a substrate. Journal of Micromechanics and Microengineering. 29. (5). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 055003.

Tsukagoshi, T., Nguyen, T.-V., Shoji, K. H., Takahashi, H., Matsumoto, K., Shimoyama, I.(2018). Cellular dynamics of bovine aortic smooth muscle cells measured using MEMS force sensors. Journal of Physics D: Applied Physics. 51. (14). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 145401.

Kohyama, S., Takahashi, H., Yoshida, S., Onoe, H., Hirayama-Shoji, K., Tsukagoshi, T., Takahata, T., Shimoyama, I.(2018). Spring constant measurement using a MEMS force and displacement sensor utilizing paralleled piezoresistive cantilevers. Journal of Micromechanics and Microengineering. 28. (4). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 045013.

Matsudaira, K., Nguyen, T.-V., Shoji, K. H., Tsukagoshi, T., Takahata, T., Shimoyama, I.(2017). MEMS piezoresistive cantilever for the direct measurement of cardiomyocyte contractile force. Journal of Micromechanics and Microengineering. 27. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 105005.

Thanh-Vinh, N., Omiya, T., Tsukagoshi, T., Hirayama, K., Noda, K., Matsumoto, K., Shimoyama, I.(2016). High-sensitivity microelectromechanical systems-based tri-axis force sensor for monitoring cellular traction force. Micro & Nano Letters. 11. (10). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 563--567.

Hirayama, K., Okitsu, T., Teramae, H., Kiriya, D., Onoe, H., Takeuchi, S.(2013). Cellular building unit integrated with microstrand-shaped bacterial cellulose. Biomaterials. 34. (10).

CONFERENCE PAPER

Hirayama-Shoji, K., Aizenshtadt, A., Wilhelmsen, I., Amirola Martinez, M., Krauss, S.(2023). Perfusable liver model for ``on chip'' disease modelling. MPS World Summit 2023. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 93.

Matsudaira, K., Takahashi, H., Hirayama-Shoji, K., Nguyen, T.-V., Tsukagoshi, T., Shimoyama, I.(2018). Load dependency measurement of iPS cell-derived cardiomyocytes' contraction. IEEE 31st International Conference on Micro Electro Mechanical Systems (MEMS 2018). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 129--132.

Hirayama-Shoji, K., Matsudaira, K., Tsukagoshi, T., Nguyen, T.-V., Noda, K., Shimoyama, I.(2017). Cantilever array for measuring traction forces of cells in a confined space. 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 191--193.

Matsudaira, K., Nguyen, T.-V., Hirayama-Shoji, K., Tsukagoshi, T., Takahata, T., Shimoyama, I.(2017). MEMS force sensor array for evaluating the contractility of iPS cell-derived cardiomyocytes. 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS 2017). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 36--38.

Kohyama, S., Takahashi, H., Yoshida, S., Onoe, H., Hirayama-Shoji, K., Tsukagoshi, T., Takahata, T., Shimoyama, I.(2017). MEMS force and displacement sensor for measuring spring constant of hydrogel microparticles. IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS 2017). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 1040--1043.

Park, H., Thanh-Vinh, N., Hirayama, K., Tsukagoshi, T., Noda, K., Takahata, T., Matsumoto, K., Shimoyama, I.(2016). Measuring the vibration of cells subjected to ultrasound using a MEMS-based force sensor array. 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2016).

Noda, K., Hirayama, K., Matsumoto, K., Shimoyama, I.(2016). Micro pillars with thin hydrophobic layer formed on the side walls to prevent cell protrusion toward side wall. 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2016). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 501--504.

Hirayama, K., Tsukagoshi, T., Thanh-Vinh, N., Ichikawa, Y., Shimoyama, I.(2016). Piezoresistive cantilever integrated microfluidic channel for measuring cellular properties. 29th IEEE International Conference on Micro Electro Mechanical Systems (MEMS 2016). Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 698--700.

Omiya, T., Tsukagoshi, T., Hirayama, K., Thanh-Vinh, N., Noda, K., Matsumoto, K., Shimoyama, I.(2015). Micropillar type three-axis force sensor for measurement of cellular force. Proceedings of IEEE Transducers 2015. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 188--191.

Hirayama, K., Heo, Y. J., Takeuchi, S.(2014). Formation of cross-shaped Escherichia coli. Proceedings of IEEE MEMS 2014. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 175--176.

Karita, Y., Hirayama, K., Onoe, H., Takeuchi, S.(2014). Micropatterning of bacterial cellulose as degradable substrate for cell culture. Proceedings of IEEE MEMS 2014. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 518--519.

Hirayama, K., Onoe, H., Takeuchi, S.(2012). 3D microfluidics formed with hydrogel sacrificial structures. Proceedings of IEEE MEMS 2012. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 200--203.

Hirayama, K., Kiriya, D., Onoe, H., Takeuchi, S.(2011). Biofilms in hydrogel core-shell fibers. Proceedings of IEEE MEMS 2011. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 845--848.

Hirayama, K., Kiriya, D., Onoe, H., Takeuchi, S.(2011). Microbially-fabricated cellulose microstrands in the core of hydrogel fibers. Proceedings of $μ$TAS 2011. Microsoft.AspNetCore.Mvc.Localization.LocalizedHtmlString 689--691.

Hirayama, K., Kiriya, D., Onoe, H., Takeuchi, S.(2010). Fabrication of bacterial fiber using gel. The 5th Meeting of Innovative Nanoscience of Supermolecular Motor Proteins Working in Biomembranes.

Hirayama, K., Kiriya, D., Onoe, H., Takeuchi, S.(2010). Fabrication of gel fiber harboring useful bacteria at high density. The 2nd Symposium of Micro/Nano Engineering.

Hirayama, K., Tokuda, G., Watanabe, H., Kitamoto, K., Arioka, M.(2009). Characterization and application of termite endogenous beta-1,4-glucanases produced in Aspergillus oryzae. The 9th Annual Meeting of Fungal Molecular Biology.

Hirayama, K., Tokuda, G., Watanabe, H., Kitamoto, K., Arioka, M.(2009). Production and characterization of termite endogenous beta-1,4-glucanases in Aspergillus oryzae. The 35th Annual Meeting of Japan Society for Bioscience, Biotechnology, Agrochemistry.

Hirayama, K., Tokuda, G., Watanabe, H., Kitamoto, K., Arioka, M.(2008). Production and purification of termite endogenous beta-1,4-glucanases in Aspergillus oryzae. The 8th Annual Meeting of Fungal Molecular Biology.

OTHER

Onoe, H., Ikeda, K., Hirayama-Shoji, K.(2019). Cell fiber manufacturing system, cell fiber manufacturing method and program.

Hirayama, K., Kiriya, D., Onoe, H., Takeuchi, S.(2011). Porous bacterial cellulose fiber and its fabrication methods.