Profile Details

Create Project

★★★★★

☆☆☆☆☆

USD 59 /hr

★★★★★

☆☆☆☆☆

Hire Dr. Karthik R.

United States

USD 59 /hr

10 years of experience in the field of Life science research, scientific writing and Mentoring

Profile Summary

More than 5 years of experience in Planning and Execution of individual research projects in the field of Microbiology, Structural biology (NMR), cell and molecular biology, Protein Engineering, Small Protein Inhibitors, protein production and virology,. Established collaborations with multi-disciplinary teams and successfully completed projects within stipulated deadline, that has resulted in quality publications in scientific journals. Mentored more than 10 students (including Undergraduate and new PhD students) for research projects and lab training in addition to the teaching duties Successfully developed the Safety Management System (SMS) in the lab by acting as the safety Lead, preparing and managing safety compliance documents for Good Laboratory Practice (GLP) in accordance to the Organization’s safety regulatory framework, in addition to the assigned research projects. Demonstrated strong Communication skills, by being able to present ideas clearly and concisely in project meeting or scientific conferences, as evidenced by winning gold medal for oral presentation in a graduate congress.

Subject Matter Expertise

• ★ Molecular Biology
• ★ Protein/Enzyme Engineering
• ★ Research Methodology
• ☆ NMR Spectroscopy
• ☆ Biology/Life Sciences
• ☆ Biochemistry
• ☆ Structural Biology
• ☆ Science Education
• ☆ Product Compliance
• ☆ Technical & Scientific Writing

Services

• Writing
• Research

Writing Technical Writing

Research Fact Checking, Gray Literature Search, Systematic Literature Review

Work Experience

Research Investigator

Incyte Corporation

September 2022 - Present

Research Investigator - Antibody Drug Discovery

Incyte (United States)

September 2022 - Present

Postdoctoral fellow

University of Texas Southwestern Medical Center

February 2019 - September 2022

Research Fellow

National University of Singapore

July 2017 - December 2018

Education

PhD - Biological Science

National University of Singapore

January 2013 - May 2017

PhD (Biological Science)

National University of Singapore

January 2013 - May 2017

M.Phil - Biomedical Technology

Scree Chitra Institute for medical science and Technology

August 2010 - July 2011

MSc - Biotechnology

Annamalai university

August 2005 - May 2010

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Karthik Ramesh, Daniel M. Rosenbaum (2022). Molecular basis for ligand modulation of the cannabinoid CB 1 receptor . British Journal of Pharmacology.

Karthik Ramesh, Varsha Ashok Walvekar, Chacko Jobichen, Muthu Kannan, J. Sivaraman, R. Manjunatha Kini, Yu Keung Mok(2022). Crystal structure of Aedes aegypti trypsin inhibitor in complex with μ‐plasmin reveals role for scaffold stability in Kazal‐type serine protease inhibitor . Protein Science. 31. (2). p. 470--484. Wiley

Karthik Ramesh and Sri Anusha Matta and Fook Tim Chew and Yu Keung Mok(2020). Exonic mutations associated with atopic dermatitis disrupt lympho‐epithelial Kazal‐type related inhibitor action and enhance its degradation . Allergy. 75. (2). p. 403--411. Wiley

Rustam Ali and Lindsay D. Clark and Jacob A. Zahm and Andrew Lemoff and Karthik Ramesh and Daniel M. Rosenbaum and Michael K. Rosen(2019). Improved strategy for isoleucine 1H/13C methyl labeling in Pichia pastoris . Journal of Biomolecular NMR. 73. (12). p. 687--697. Springer Science and Business Media {LLC}

Zhenhua Shao and Wei Yan and Karen Chapman and Karthik Ramesh and Aaron J. Ferrell and Jie Yin and Xuehui Wang and Qingping Xu and Daniel M. Rosenbaum(2019). Structure of an allosteric modulator bound to the CB1 cannabinoid receptor . Nature Chemical Biology. 15. (12). p. 1199--1205. Springer Science and Business Media {LLC}

Karthik Ramesh and Varsha A. Walvekar and Benjamin Wong and Ahmed Mahmoud Mohammed Sayed and Doroth{\'{e}}e Miss{\'{e}} and R. Manjunatha Kini and Yu Keung Mok and Julien Pompon(2019). Increased Mosquito Midgut Infection by Dengue Virus Recruitment of Plasmin Is Blocked by an Endogenous Kazal-type Inhibitor . iScience. 21. p. 564--576. Elsevier {BV}

(2018). Homologous Lympho-Epithelial Kazal-type Inhibitor Domains Delay Blood Coagulation by Inhibiting Factor X and XI with Differential Specificity . Structure (London, England : 1993).

(2017). Structural basis for the bacterial membrane insertion of dermcidin peptide, DCD-1L . Scientific reports.

(2015). Structure of AcrH-AopB Chaperone-Translocator Complex Reveals a Role for Membrane Hairpins in Type III Secretion System Translocon Assembly . Structure (London, England : 1993).