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Hire Dr. Kalpana P.

India

USD 100 /hr

Tained Biologist | 11 years of experience | Structure biology|Biophysics|Biochemistry|Membrane proteins|Druggable target

Profile Summary

Trained biologist (experience ~ 11 years) pursuing challenging biological problems. I am highly experienced in Biophysics, Biochemistry, Cell and molecular biology, Biotechnology, Single molecule imaging research, molecular dynamics and simulation, macromolecular docking, druggability potential of biomolecules, small angle X-ray scattering, membrane proteins, viral proteins, immunologically relevant proteins, lipid scrambling, lipid transport, organelle contact site etc. I am good at multitasking when necessary to achieve goals in a timely fashion. I have good communication skills necessary for negotiating and solving problems quickly, accurately, and efficiently. I am good at handling untrained personals for research training. I have authored, published and reviewed several academic manuscripts in various top tier journals, which have equipped me with good writing and data analysis skills.

Subject Matter Expertise

• ☆ Computational Biology
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Biochemical Assays
• ☆ Structural Biology
• ☆ Enzyme Activity Assays
• ☆ Binding Assays
• ☆ Molecular Biology
• ☆ PCR
• ☆ Molecular Cloning
• ☆ Mutagenesis
• ☆ Cell Biology
• ☆ Cell-Based Assays
• ☆ Cell Signaling Pathways
• ☆ Membrane Biology
• ☆ Biophysics
• ☆ Biotechnology & Bioengineering
• ☆ Recombinant Protein Expression
• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Fluorescence Microscopy
• ☆ Biological Engineering
• ☆ Cell Culture
• ☆ Cell Surface Receptors
• ☆ Drug Discovery
• ☆ Drug Target Identification
• ☆ Drug Design
• ☆ Structure-Activity Relationship (SAR) Studies
• ☆ Vaccine Development
• ☆ Human Biology

Services

• Writing
• Research
• Consulting
• Data & AI

Writing Technical Writing, Copywriting

Research Market Research, User Research, Feasibility Study, Gap Analysis, Gray Literature Search, Systematic Literature Review

Consulting Scientific and Technical Consulting

Data & AI Statistical Analysis, Data Visualization

Work Experience

IPDF

Indian Institute of Technology Guwahati

June 2019 - Present

Post Doctoral Fellow

Weill Cornell Medical College

April 2015 - February 2019

Education

PhD

Institute of Microbial Technology CSIR

February 2009 - June 2014

M. Sc. Bioinformatics

Banaras Hindu University

June 2006 - June 2008

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2020). Glutamate binding triggers monomerization of unliganded mGluR2 dimers . Archives of biochemistry and biophysics.

Kalpana Pandey, Goutam Chandra, Aurelia Defour, Kamel Mamchoui, Soumya Mishra, Vincent Mouly, SenChandra Sreetama, Mohammad Mahad Ahmad, Ibrahim Mahjneh, Hiroki Morizono, et al.(2019). Dysregulated calcium homeostasis prevents plasma membrane repair in Anoctamin 5/TMEM16E-deficient patient muscle cells . Cell Death Discovery. 5. (1). Springer Science and Business Media {LLC}

(2019). Unstructured loop is essential for the activation of mGluR2 . Biochemical and biophysical research communications.

(2018). Scrambling of natural and fluorescently tagged phosphatidylinositol by reconstituted G protein–coupled receptor and TMEM16 scramblases . Journal of Biological Chemistry.

(2018). Out-of-the-groove transport of lipids by TMEM16 and GPCR scramblases . Proceedings of the National Academy of Sciences.

(2018). Structural basis of sterol binding and transport by a yeast StARkin domain . Journal of Biological Chemistry.

(2018). Mechanisms of Lipid Scrambling by the G Protein-Coupled Receptor Opsin . Structure.

Pandey, K., Ploier, B., Goren, M.A., Levitz, J., Khelashvili, G., Menon, A.K.(2017). An engineered opsin monomer scrambles phospholipids . Scientific Reports. 7. (1).

Ploier, B., Caro, L.N., Morizumi, T., Pandey, K., Pearring, J.N., Goren, M.A., Finnemann, S.C., Graumann, J., Arshavsky, V.Y., Dittman, J.S., et al.(2016). Dimerization deficiency of enigmatic retinitis pigmentosa-linked rhodopsin mutants . Nature Communications. 7.

Chauhan, N., Farine, L., Pandey, K., Menon, A.K., Bütikofer, P.(2016). Lipid topogenesis - 35 years on . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1861. (8). p. 757-766.

Singh, S., Pandey, K., Rathore, Y.S., Sagar, A., Pattnaik, U.B.K., Ashish, G.(2014). A communication network within the cytoplasmic domain of toll-like receptors has remained conserved during evolution . Journal of Biomolecular Structure and Dynamics. 32. (5). p. 694-700.

Pandey, K., Rathore, Y.S., Nath, S.K., Ashish(2014). Towards strain-independent anti-influenza peptides: A SAXS- and modeling-based study . Journal of Biomolecular Structure and Dynamics. 32. (11). p. 1720-1733.

Pandey, K., Dhoke, R.R., Rathore, Y.S., Nath, S.K., Verma, N., Bawa, S., Ashish(2014). Low pH overrides the need of calcium ions for the shape-function relationship of calmodulin: Resolving prevailing debates . Journal of Physical Chemistry B. 118. (19). p. 5059-5074.

Rathore, Y.S., Rehan, M., Pandey, K., Sahni, G., Ashish(2012). First structural model of full-length human tissue-plasminogen activator: A saxs data-based modeling study . Journal of Physical Chemistry B. 116. (1). p. 496-502.

OTHER

Kalpana Pandey, George Khelashvili, Neha Chauhan, David Eliezer, Anant K. Menon(2019). Water for sterol: an unusual mechanism of sterol egress from a StARkin domain . Cold Spring Harbor Laboratory