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USD 90 /hr

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Hire Dr. Joshur A.

Singapore

USD 90 /hr

10+ Years Expert Cell Therapy Scientist | Pre-IND FDA/EMA Assay Validation & CAR-T Engineering

Profile Summary

Senior Cell Therapy and Bioprocessing scientist with over 10 years of industrial and translational research experience bridging corporate biotech innovation with world-class regulatory execution. Specialized in CAR-T engineering for oncology targets, validation of pre-IND analytical assays, and high-throughput cellular screening platforms. Proven track recordin: 1. Designing and validating complex analytical assays (including Viral Copy Number / VCN) for pre-IND filing and EMA to launch clinical trials. 2. Expert in standard operating procedure (SOP) development, mammalian primary cell systems (T-cells, MSCs, iPSCs), and Design of Experiments (DoE) methodology to dramatically optimize bioprocess yields. Core Freelance & Consulting Competencies: 1. Cell Therapy Innovation: Optimization of T-cell and mesenchymal stromal cell (MSC) platforms, molecular cloning, lentiviral production, and multi-color FACS isolation. 2. Assay Validation & Quality Control: Development and rigorous validation of Viral Copy Number (VCN) assays aligned with FDA and EMA guidelines. 3. Data Analytics & Software Mastery: Expert at transforming raw laboratory data into clear, regulatory-grade insights using FlowJo for advanced flow cytometry, GraphPad Prism for statistical modeling, and SnapGene and Benchling for precise molecular cloning and sequence design. 4. Technical Writing & Communications: Technical reporting, clinical study data interpretation, and high-impact manuscript editing for peer-reviewed journals.

Subject Matter Expertise

• ☆ Cell Biology
• ☆ Stem Cell Research
• ☆ Drug Development
• ☆ Immunotherapy

Services

• Writing

Writing Technical Writing

Work Experience

Research Associate

National University of Singapore

November 2025 - Present

Education

Doctoral Program

National University Singapore

August 2023 - Present

Certifications

• Design of Experiment Specialization Certificate

  Arizona State University (via Coursera)

  https://coursera.org/share/bf3fd9c0f15c99d9b8eeff643f777e55

  August 2025 - Present

Publications

JOURNAL ARTICLE

Joshur Ang, Melvin Khee Shing Leow, Xinyan Bi, Ee Tzun Koh, Craig McFarlane (2023). Alterations in SAMD9, AHSG, FRG2C, and FGFR4 Genes in a Case of Late-Onset Massive Tumoral Calcinosis . AACE Clinical Case Reports.

Joshur Ang, Hongliang Qian, Florence Pik Hoon Gay, Jane Wan Lu Pang, Yunqin Lee, Hwee Ching Tan, Erica SH Lek, Dario Campana, Ying Xim Tan (2022). Development of Anti-CD3 Chimeric Antigen Receptor (CAR)-T Cells for Allogeneic Cell Therapy of Peripheral T-Cell Lymphoma (PTCL) . Blood.

Joshur Ang, Yong‐An Lee, Deepak Raghothaman, Premkumar Jayaraman, Kim L. Teo, Fahima J. Khan, Shaul Reuveny, Young‐Tae Chang, Nam‐Young Kang, Steve Oh (2019). Rapid Detection of Senescent Mesenchymal Stromal Cells by a Fluorescent Probe . Biotechnology Journal.

Joshur Ang, Manfredi LH, Ang J, Peker N, Dagda RK, McFarlane C (2019). G protein-coupled receptor kinase 2 regulates mitochondrial bioenergetics and impairs myostatin-mediated autophagy in muscle cells . American journal of physiology. Cell physiology.