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Hire Dr. Jolene H.

Canada

Profile Summary

I am an experienced postdoctoral researcher with a demonstrated history of working in the research industry. I am skilled in experimental biology, research analysis, and scientific writing/editing. My research interests lie in oncology, neurosciences and therapeutics, and I am currently working on drug screens and mechanisms of action in brain cancers (with a primary focus on glioblastoma) and Huntington's disease in patient models.

Subject Matter Expertise

• ☆ Molecular Biology
• ☆ Genetics
• ☆ Stem Cell Research
• ☆ Neuroscience
• ☆ Small Molecule Drug Development
• ☆ Drug-Drug Interactions
• ☆ Medical Sciences
• ☆ Technical & Scientific Writing

Services

• Writing
• Consulting
• Product Development

Work Experience

Research Scientist

Veredus Laboratories

2019 - Present

Postdoctoral Fellow

University of Toronto

2017 - 2019

Research Scientist

Veredus Laboratories

2017 - 2017

Research Fellow

National University of Singapore

2015 - 2016

Education

BSc (Life Science (Biomedical Sciences))

National University of Singapore

2006 - 2010

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

(2019). Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4 . Nature Communications. 10. (1).

(2019). Design and characterization of mutant and wildtype huntingtin proteins produced from a toolkit of scalable eukaryotic expression systems . Journal of Biological Chemistry. 294. (17). p. 6986-7001.

(2017). Hypoxia is a Key Driver of Alternative Splicing in Human Breast Cancer Cells . Scientific Reports. 7. (1).

Luecke-Johansson, S., Gralla, M., Luecke-Johansson, S., Gralla, M., Rundqvist, H., Ho, J.C., Johnson, R.S., Gradin, K., Poellinger, L.(2017). A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase . Molecular and Cellular Biology. 37. (13).

(2017). Inhibition of the H3K9 methyltransferase G9A attenuates oncogenicity and activates the hypoxia signaling pathway . PLoS ONE. 12. (11).

(2016). The impact of mechanical stress on stem cell properties: The link between cell shape and pluripotency . Histology and Histopathology. 31. (1). p. 41-50.

(2014). The hypoxia-inducible epigenetic regulators Jmjd1a and G9a provide a mechanistic link between angiogenesis and tumor growth . Molecular and Cellular Biology. 34. (19). p. 3702-3720.

(2012). Dual inhibition of Src and GSK3 maintains mouse embryonic stem cells, whose differentiation is mechanically regulated by Src signaling . Stem Cells. 30. (7). p. 1394-1404.