Janete Santos - Freelance Clinical Laboratory Science Consultant in Porto, Portugal

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Portugal

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Profile Summary

Janete Quelhas-Santos graduated in Biology at University of Aveiro in 2005.
In 2006 she joined the Nephrology Research and Development Unit (UIDN) from the Faculty of Medicine of the University of Porto, as a research fellow, and since then she has been working in the research line titled “Assessment of neurohumoral activation in chronic kidney disease: role of sympathetic, dopaminergic and natriuretic peptide systems”.
In 2008 she concluded a post-graduation course in Molecular Oncology and Medicine at Faculty of Medicine of University of Porto.
In 2013, she finished her PhD in Biomedicine at the Faculty of Medicine of University of Porto with a thesis titled: "Contribution to the study of renalase in chronic kidney disease". Presently, she is carrying out her post-doctoral studies at the Nephrology and Infectious Diseases Research and Development Group, INEB-(I3S). She is enrolled in the research of novel biomarkers to assess endothelial dysfunction, with clinical importance in chronic kidney disease and that may aid in directing therapy to preserve a healthy endothelium and reduce cardiovascular risk.

Subject Matter Expertise

Services

Writing
Research
Data & AI

Writing Clinical Trial Documentation, Technical Writing

Research Gray Literature Search, Systematic Literature Review

Data & AI Statistical Analysis, Data Visualization

Work Experience

Assistant Research

Faculty of Medicine of University of Porto

September 2019 - Present

Junior Research

Faculty of Medicine of University of Porto

June 2019 - September 2019

Assistant Research - NORTE-01-0145-FEDER-000012 - “Structured Programme on Bioengineering Therapies for Infectious Diseases and Tissue Regeneration” in the frame of “Norte2020 - Programa Operacional Regional do Norte”.

I3S- Institute for Research and Innovation in Health

May 2016 - April 2019

Post-doctoral Research fellowship

Faculty of Medicine of UP

April 2013 - March 2015

PhD fellowship - FCT/FEDER - SFRH/BD/39066/2007

Portuguese Foundation for Science and Technology

October 2008 - March 2013

Research fellowship - POCI/SAU-OBS/55288/2004

Faculty of Medicine of UP

August 2006 - September 2008

Education

University of Porto (Faculty of Medicine)

PhD in Biomedicine

October 2008 - October 2013

University of Porto (Faculty of Medicine)

Post-Graduation in Molecular Oncology and Medicine

September 2007 - February 2008

University of Aveiro (Department of Biology)

Degree in Biology

September 2000 - March 2006

Certifications

Certification details not provided.

Publications

JOURNAL ARTICLE

Fernandes-Cerqueira Cátia, Quelhas-Santos Janete, Sampaio-Maia Benedita, Simões-Silva Liliana, Soares-Silva Isabel, Roncon-Albuquerque Roberto, Pestana Manuel(2018). Calcitriol Prevents Cardiovascular Repercussions in Puromycin Aminonucleoside-Induced Nephrotic Syndrome . BioMed Research International. 2018. p. 1--10. Hindawi Limited

Cerqueira, Ana, Cristino, Luís, Quelhas Santos, Janete, Correia, Flora, Pestana, Manuel(2018). SP388 THE DECREASE IN PHOSPHATE INTAKE IMPROVES ENDOTHELIAL FUNCTION IN PRE-DIALYSIS CKD PATIENTS. Nephrology Dialysis Transplantation. 33. (suppl_1). p. i477--i477.

Martins, Sandra, Quelhas-Santos, Janete(2016). Circulating Endothelial Progenitor Cells : A Review of Definition , Characterization and Identification. Research & Reviews: Research Journal of Biology.

Ferreira, Ines, Quelhas-Santos, Janete, Martins, Sandra, Cerqueira, Ana, Carmo, Rute, Pestana, Manuel(2016). COMPENSATORY RECRUITMENT OF ENDOTHELIAL PROGENITOR CELLS IN LUPUS NEPHRITIS PATIENTS WITH PRESERVED RENAL FUNCTION . Nephrology Dialysis Transplantation. 31. p. 392-393.

Martins, Sandra, Quelhas-Santos, Janete(2016). Circulating Endothelial Progenitor Cells : A Review of Definition. Research & Reviews: Research Journal of Biology.

(2015). Assessment of renalase activity on catecholamines degradation . The Open Hypertension Journal.

Quelhas-Santos J, Pestana M, Current hypertension reviews, 2015 .

Quelhas-Santos J, Pestana M(2015). Plasma Renalase Expression in Chronic Kidney Disease: Differences and Similarities between Humans and Rats .

Quelhas-Santos, Janete, Sampaio-Maia, Benedita, Remião, Fernando, Serrão, Paula, Soares-Silva, Isabel, Desir, Gary V., Pestana, Manuel(2015). Assessment of Renalase Activity on Catecholamines Degradation. The Open Hypertension Journal. 7. (1).

Cerqueira, Ana, Quelhas Santos, Janete, Martins, Sandra, Sarmento Dias, Margarida, Pestana, Manuel(2015). SP321 RENALASE. Nephrology Dialysis Transplanation. 30. (suppl_3). p. iii485--iii485.

Quelhas-Santos, Janete, Serrao, Maria Paula, Soares-Silva, Isabel, Fernandes-Cerqueira, Catia, Simoes-Silva, Liliana, Pinho, Maria Joao, Remiao, Fernando, Sampaio-Maia, Benedita, Desir, Gary V., Pestana, Manuel(2015). Renalase regulates peripheral and central dopaminergic activities . American Journal of Physiology-Renal Physiology. 308. (2). p. F84--F91.

Cerqueira, A., Quelhas Santos, J., Martins, S., Sarmento Dias, M., Pestana, M.(2015). RENALASE . Journal of Hypertension. 33. p. E367--E367.

Cerqueira, Ana, Quelhas-Santos, Janete, Pestana, Manuel(2015). Endothelial function assessed by peripheral arterial tonometry is not related with FGF23 serum levels in pre-dialysis CKD patients . Portuguese Journal of Nephrology & Hypertension. 29. (1). p. 48--55.

Quelhas-Santos, J., Martins, S., Leitão, C., Oliveira, H., Cerqueira, A., Pestana, M.(2015). Pp. 13.07: Reduced Endothelial Regenerative Capacity In Chronic Kidney Disease . Journal of Hypertension. 33. p. e239--e240.

Cerqueira, Ana, Quelhas Santos, Janete, Martins, Sandra, Sarmento Dias, Margarida, Pestana, Manuel(2015). SP321 RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS. Nephrology Dialysis Transplanation. 30. (suppl_3). p. iii485.

Cerqueira, Ana, Quelhas-Santos, Janete, Pestana, Manuel(2015). A função endotelial avaliada pela tonometria arterial periférica não se correlaciona com os níveis séricos de FGF-23 em doentes renais crónicos pré-diálise. Portuguese Journal of Nephrology & Hypertension. 29. (1). p. 48-55.

Cerqueira, A., Quelhas Santos, J., Martins, S., Sarmento Dias, M., Pestana, M.(2015). RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS . Journal of Hypertension. 33. p. E367.

Quelhas-Santos J, Serrão MP, Soares-Silva I, Fernandes-Cerqueira C, Simões-Silva L, Pinho MJ, Remião F, Sampaio-Maia B, Desir GV, Pestana M, American journal of physiology. Renal physiology, 2014 .

Quelhas-Santos J, Soares-Silva I, Fernandes-Cerqueira C, Simões-Silva L, Ferreira I, Carvalho C, Coentrão L, Vaz R, Sampaio-Maia B, Pestana M, Experimental biology and medicine (Maywood, N.J.), 2014, vol. 239, no. 4, pp. 502-508 .

Quelhas-Santos J, Soares-Silva I, Fernandes-Cerqueira C, Simões-Silva L, Ferreira I, Carvalho C, Coentrão L, Vaz R, Sampaio-Maia B, Pestana M(2014). Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients .

Cerqueira, Ana, Quelhas-Santos, Janete, Pestana, Manuel(2014). ENDOTHELIAL FUNCTION ASSESSED BY PERIPHERAL ARTERIAL TONOMETRY IS NOT RELATED WITH FGF-23 SERUM LEVELS IN PREDIALYSIS CKD PATIENTS . Nephrology Dialysis Transplantation. 29. p. 374--374.

Quelhas-Santos, Janete(2014). Será a renalase um novo regulador da atividade renal dopaminérgica?. Portuguese Journal of Nephrology & Hypertension. 28. (1). p. 31--39.

Santos-Araújo, C., Roncon-Albuquerque Jr, R., Moreira-Rodrigues, M., Henriques-Coelho, T., Quelhas-Santos, J., Faria, B., Sampaio-Maia, B., Leite-Moreira, A. F., Pestana, M.(2014). Natriuretic peptide system modulation in uninephrectomized rats . Experimental and Clinical Cardiology. 20. (8). p. 2368--2387.

Quelhas-Santos, J., Pestana, M.(2014). Plasma renalase in chronic kidney disease: differences and similarities between humans and rats . Curr Hypertens Rev. 10. (3). p. 166-70.

Quelhas-Santos, Janete, Soares-Silva, Isabel, Fernandes-Cerqueira, Catia, Simoes-Silva, Liliana, Ferreira, Ines, Carvalho, Catarina, Coentrao, Luis, Vaz, Raquel, Sampaio-Maia, Benedita, Pestana, Manuel(2014). Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients . Experimental Biology and Medicine. 239. (4). p. 502-508.

Quelhas-Santos, Janete(2014). Is renalase a new regulator of renal dopaminergic activity? . Portuguese Journal of Nephrology & Hypertension. 28. (1). p. 31-39.

Quelhas-Santos, Janete(2014). Será a renalase um novo regulador da atividade renal dopaminérgica?. Portuguese Journal of Nephrology & Hypertension. 28. (1). p. 31-39.

Quelhas-Santos, J., Pestana, M.(2014). Plasma renalase in chronic kidney disease: differences and similarities between humans and rats . Curr Hypertens Rev. 10. (3). p. 166--70.

Quelhas-Santos, Janete(2014). Is renalase a new regulator of renal dopaminergic activity? . Portuguese Journal of Nephrology & Hypertension. 28. (1). p. 31--39.

Malyszko, Jolanta, Koc-Zorawska, Ewa, Banach, Maciej, Mysliwiec, Michal(2013). Letter on ‘Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney’ . Journal of hypertension. 31. (6). p. 1272--1273.

Quelhas-Santos, Janete, Pestana, Manuel(2013). Letter on 'Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney' Reply . Journal of Hypertension. 31. (6). p. 1274--1275.

Fernandes-Cerqueira, Catia, Sampaio-Maia, Benedita, Quelhas-Santos, Janete, Moreira-Rodrigues, Monica, Simoes-Silva, Liliana, Blazquez-Medela, Ana M., Martinez-Salgado, C., Lopez-Novoa, Jose M., Pestana, Manuel(2013). Concerted action of ANP and dopamine D1-receptor to regulate sodium homeostasis in nephrotic syndrome . BioMed research international. 2013. p. 397391.

Quelhas-Santos, Janete, Sampaio-Maia, Benedita, Simoes-Silva, Liliana, Serrao, Paula, Fernandes-Cerqueira, Catia, Soares-Silva, Isabel, Pestana, Manuel(2013). Sodium-dependent modulation of systemic and urinary renalase expression and activity in the rat remnant kidney . Journal of Hypertension. 31. (3). p. 543-553.

Sizova, Daria, Velazquez, Heino, Sampaio-Maia, Benedita, Quelhas-Santos, Janete, Pestana, Manuel, Desir, Gary V.(2013). Renalase regulates renal dopamine and phosphate metabolism . American Journal of Physiology-Renal Physiology. 305. (6). p. F839-F844.

Simoes-Silva, Liliana, Moreira-Rodrigues, Monica, Quelhas-Santos, Janete, Fernandes-Cerqueira, Catia, Pestana, Manuel, Soares-Silva, Isabel, Sampaio-Maia, Benedita(2013). Intestinal and renal guanylin peptides system in hypertensive obese mice . Experimental Biology and Medicine. 238. (1). p. 90-97.

Desir, Gary V., Tang, Lieqi, Wang, Peili, Li, Guoyong, Sampaio-Maia, Benedita, Quelhas-Santos, Janete, Pestana, Manuel, Velazquez, Heino(2012). Renalase Lowers Ambulatory Blood Pressure by Metabolizing Circulating Adrenaline . Journal of the American Heart Association. 1. (4).

Quelhas-santos, Janete, Serrão, Paula, Soares-silva, Isabel, Tang, Lieqi, Sampaio-maia, Benedita, Desir, Gary, Pestana, Manuel(2012). Hypertension. Nephrology Dialysis Transplantation. 27. (suppl_2). p. ii86--ii95.

Simões-Silva, Liliana, Moreira-Rodrigues, Mónica, Quelhas-Santos, Janete, Fernandes-Cerqueira, Cátia, Pestana, Manuel, Soares-Silva, Isabel, Sampaio-Maia, Benedita, Bankir, Lise, Leopold, Fezeu, Nadine, Bouby(2012). Hormones. Nephrology Dialysis Transplantation. 27. (suppl_2). p. ii330--ii332.

Simoes-Silva, Liliana, Moreira-Rodrigues, Monica, Quelhas-Santos, Janete, Fernandes-Cerqueira, Catia, Pestana, Manuel, Soares-Silva, Isabel, Sampaio-Maia, Benedita(2012). RENAL AND INTESTINAL GUANYLIN PEPTIDES SYSTEM IN A MOUSE MODEL OF DIET-INDUCED OBESITY . Nephrology Dialysis Transplantation. 27. p. 330.

Quelhas-Santos, Janete, Serrao, Paula, Soares-Silva, Isabel, Tang, Lieqi, Sampaio-Maia, Benedita, Desir, Gary, Pestana, Manuel(2012). EFFECTS OF RECOMBINANT RENALASE ON RENAL DOPAMINE ACTIVITY IN THE RENALASE KNOCKOUT MOUSE MODEL . Nephrology Dialysis Transplantation. 27. p. 93.

Moreira-Rodrigues, Monica, Quelhas-Santos, Janete, Roncon-Albuquerque, Roberto, Serrao, Paula, Leite-Moreira, Adelino, Sampaio-Maia, Benedita, Pestana, Manuel(2012). Blunted renal dopaminergic system in a mouse model of diet-induced obesity . Experimental Biology and Medicine. 237. (8). p. 949-955.

Simoes-Silva, Liliana, Moreira-Rodrigues, Monica, Quelhas-Santos, Janete, Fernandes-Cerqueira, Catia, Pestana, Manuel, Soares-Silva, Isabel, Sampaio-Maia, Benedita(2012). RENAL AND INTESTINAL GUANYLIN PEPTIDES SYSTEM IN A MOUSE MODEL OF DIET-INDUCED OBESITY . Nephrology Dialysis Transplantation. 27. p. 330--330.

Quelhas-Santos, Janete, Serrão, Paula, Fernandes-Cerqueira, Cátia, Silva, Liliana, Soares-Silva, Isabel, Sizova, Daria, Sampaio-Maia, Benedita, Desir, Gary, Pestana, Manuel(2011). renal Dopaminergic Activity Is Increased In The Renalase Knockout Mouse Model: 7b. 08. Journal of Hypertension. 29. p. e103--e103.

Silva, Liliana(2011). Assessment of guanylin peptides system in type 2 diabetes.

Wu, Yanling, Xu, Jianchao, Velazquez, Heino, Wang, Peili, Li, Guoyong, Liu, Dinggang, Sampaio-Maia, Benedita, Quelhas-Santos, Janete, Russell, Kerry, Russell, Raymond, et al.(2011). Renalase deficiency aggravates ischemic myocardial damage . Kidney International. 79. (8). p. 853-860.

Moreira-Rodrigues, Monica, Quelhas-Santos, Janete, Serrao, Paula, Fernandes-Cerqueira, Catia, Sampaio-Maia, Benedita, Pestana, Manuel(2010). Glycaemic control with insulin prevents the reduced renal dopamine D-1 receptor expression and function in streptozotocin-induced diabetes . Nephrology Dialysis Transplantation. 25. (9). p. 2945-2953.

Dos Santos, J. Quelhas, Sampaio-Maia, B., Simões-Silva, L., Fernandes-Cerqueira, C., Pestana, M.(2010). Renal And Cardiac Renalase Expression During Normal And High-salt Diets In Chronic Kidney Disease Rat Model: 2d. 06 . Journal of Hypertension. 28. p. e26.

Pestana, M., Sampaio-Maia, B., Moreira-Rodrigues, M., Fernandes-Cerqueira, C., Quelhas-Santos, J.(2009). Expression of renalase in a 3/4 nephrectomy rat model. NDT Plus. 2. (suppl 2). p. ii55--ii55.

Desir, G., Giordano, F., Liu, D., Wu, Y.(2009). Renalase deficiency aggravates cardiac ischemia and myocardial infarction. NDT Plus. 2. p. ii55--ii55.

Moreira-Rodrigues, M. I., Quelhas-Santos, J., Serrao, P., Cerqueira, C., Sampaio-Maia, B., Pestana, M.(2009). GLYCEMIC CONTROL BY INSULIN PREVENTS THE REDUCED RENAL D1 RECEPTOR EXPRESSION AND FUNCTION IN STREPTOZOTOCIN-INDUCED DIABETIC RATS . Journal of Hypertension. 27. p. S173--S173.

Pestana, M., Sampaio-Maia, B., Moreira-Rodrigues, M., Fernandes-Cerqueira, C., Quelhas-Santos, J.(2009). Expression of renalase in a 3/4 nephrectomy rat model. NDT Plus. 2. (suppl 2). p. ii55.

Desir, G., Giordano, F., Liu, D., Wu, Y.(2009). Renalase deficiency aggravates cardiac ischemia and myocardial infarction. NDT Plus. 2. p. ii55.

Santos-Araujo, Carla, Roncon-Albuquerque, Roberto, Jr., Moreira-Rodrigues, Monica, Henriques-Coelho, Tiago, Quelhas-Santos, Janete, Faria, Bernardo, Sampaio-Maia, Benedita, Leite-Moreira, Adelino F., Pestana, Manuel(2009). Local modulation of the natriuretic peptide system in the rat remnant kidney . Nephrology Dialysis Transplantation. 24. (6). p. 1774-1782.

Moreira-Rodrigues, M., Roncon-Albuquerque, R., Jr., Henriques-Coelho, T., Lourenco, A. P., Sampaio-Maia, B., Santos, J., Pestana, M., Leite-Moreira, A. F.(2007). Cardiac remodeling and dysfunction in nephrotic syndrome . Kidney International. 71. (12). p. 1240-1248.

Moreira Rodrigues, M., Santos, J., Roncon Albuquerque, R., Sampaio-Maia, Benedita, Leite-Moreira, A. F., Pestana, M.(2007). Enhanced renal dopaminergic activity in high-fat diet-induced type 2 diabetic mice . NEPHROLOGY DIALYSIS TRANSPLANTATION.

Moreira Rodrigues, M., Roncon Albuquerque, R., Henriques Coelho, T., Lourenco, Andre P., Sampaio-Maia, Benedita, Santos, J., Leite-Moreira, A. F., Pestana, M.(2007). Puromycin aminonucleoside-induced nephrotic syndrome presents cardiac atrophy, contractile dysfunction and cytokine activation . NEPHROLOGY DIALYSIS TRANSPLANTATION.

Vendeira, P., Santos, J., Cordeiro, A., Figueiredo, A., Godinho, F., Martins, I., Almeida, H., Neves, D.(2007). Ultrastructural characterization and immunohistochemical study of expression of Ang1. The Journal of Sexual Medicine. 4. p. 172.

(2006). Distribuição do território endotelial e da expressão de VEGF em modelo experimental de pénis de rato. Efeitos da orquidectomia bilateral e do envelhecimento . Acta Urológica 23(2): 45-52.

Costa, C., Tomada, N., Vendeira, P., Almeida, H., Santos, J., Magalhães, D.(2006). DIFFERENT TISSUE CELL TURNOVER IN THE RAT PENIS DURING AGING: A COMPARATIVE STUDY. European Urology Supplements. 5. (2). p. 28--28.

Tomada, N., Santos, J., Neves, D., Vendeira, P.(2006). Confocal Microscopy Analysis of Vegf and Vegf Receptor-1 (flt-1) Expression in Human Corpora Cavernosa: 155. The Journal of Sexual Medicine. 3. p. 63--63.

Santos, J., Neves, D., Tomada, N., Almeida, H., Vendeira, P.(2005). Expressão do VEGF e dos receptores Flt-1 e Flk-1 no corpo cavernoso do rato. Acção do envelhecimento e da orquidectomia . Revista Internacional de Andrología. 3. (3). p. 120-127.

DISSERTATION THESIS

Martins, Sandra Cristina Pinto(2015). Evaluation of circulating endothelial progenitor cells by multicolor flow cytometry in chronic kidney disease patients .

Janete Maria Quelhas dos Santos(2013). Contribution to the study of the renalase in chronic renal disease .

BOOK CHAPTER

Santos, Janete, Neves, Delminda, Tomada, Nuno, Almeida, Henrique, Vendeira, Pedro(2006). Aging and Orchidectomy Modulate Expression of VEGF Receptors (Flt-1 and Flk-1) on Corpus Cavernosum of the Rat . 1067164--172

CONFERENCE PAPER

EXPRESSION LEVELS OF RENALASE IN A CHRONIC RENAL INSUFFICIENCY RAT MODEL OVER TIME @inproceedings{RID:0121191642391-190, title = {EXPRESSION LEVELS OF RENALASE IN A CHRONIC RENAL INSUFFICIENCY RAT MODEL OVER TIME}, booktitle = {}, year = {}, author = {Dos Santos, J. Quelhas and Fernandes-Cerqueira, C. and Moreira-Rodrigues, M. and Sampaio-Maia, B. and Pestana, M.} } .