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USD 150 /hr
Hire Dr. Jamie S.
United States
USD 150 /hr
PhD in Computational Chemistry and Biophysics. Expert in creation of atomic-level models.
Profile Summary
Subject Matter Expertise
Services
Work Experience
Scientist
Janssen Pharmaceuticals
May 2019 - Present
Applications Scientist
Schrodinger
April 2018 - May 2019
Education
PhD in Chemistry
UC San Diego
August 2012 - November 2016
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Jennifer M. Chambers, Wade Miller, Giovanni Quichocho, Viraj Upadhye, Diego Avellaneda Matteo, Andrey A. Bobkov, Christal D. Sohl, Jamie M. Schiffer(2020). Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 ({IDH}1) Are Critical for Allosteric Inhibitor Binding and Activity . Biochemistry. American Chemical Society ({ACS})
Emilia P. Barros, Jamie M. Schiffer, Anastassia Vorobieva, Jiayi Dou, David Baker, Rommie E. Amaro(2019). Improving the Efficiency of Ligand-Binding Protein Design with Molecular Dynamics Simulations . Journal of Chemical Theory and Computation. 15. (10). p. 5703--5715. American Chemical Society ({ACS})
Luthra A, Paranagama N, Swinehart W, Bayooz S, Phan P, Quach V, Schiffer JM, Stec B, Iwata-Reuyl D, Swairjo MA(2019). Conformational communication mediates the reset step in t6A biosynthesis . Nucleic acids research.
Luo M, Dommer AC, Schiffer JM, Rez DJ, Mitchell AR, Amaro RE, Grassian VH(2019). Surfactant Charge Modulates Structure and Stability of Lipase-Embedded Monolayers at Marine-Relevant Aerosol Surfaces . Langmuir : the ACS journal of surfaces and colloids.
Jamie M. Schiffer, Johnnie Lyman, Debra Byrd, Hercules Silverstein, Mathew D. Halls(2019). Microplastics Outreach Program: A Systems-Thinking Approach To Teach High School Students about the Chemistry and Impacts of Plastics . Journal of Chemical Education. American Chemical Society ({ACS})
Feher VA, Schiffer JM, Mermelstein DJ, Mih N, Pierce LCT, McCammon JA, Amaro RE(2018). Mechanisms for Benzene Dissociation through the Excited State of T4 Lysozyme L99A Mutant . Biophysical journal.
Schiffer JM, Mael LE, Prather KA, Amaro RE, Grassian VH(2018). Sea Spray Aerosol: Where Marine Biology Meets Atmospheric Chemistry . ACS central science.
Avellaneda Matteo D, Wells GA, Luna LA, Grunseth AJ, Zagnitko O, Scott DA, Hoang A, Luthra A, Swairjo MA, Schiffer JM, et al.(2018). Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants . The Biochemical journal.
Schiffer JM, Luo M, Dommer AC, Thoron G, Pendergraft M, Santander MV, Lucero D, Pecora de Barros E, Prather KA, Grassian VH, et al.(2018). Impacts of Lipase Enzyme on the Surface Properties of Marine Aerosols . The journal of physical chemistry letters.
Mulero MC, Shahabi S, Ko MS, Schiffer JM, Huang DB, Wang VY, Amaro RE, Huxford T, Ghosh G(2018). Protein Cofactors Are Essential for High-Affinity DNA Binding by the Nuclear Factor κB RelA Subunit . Biochemistry.
Schiffer JM, Malmstrom RD, Parnell J, Ramirez-Sarmiento C, Reyes J, Amaro RE, Komives EA(2016). Model of the Ankyrin and SOCS Box Protein, ASB9, E3 Ligase Reveals a Mechanism for Dynamic Ubiquitin Transfer . Structure (London, England : 1993).
Balasubramaniam D, Schiffer J, Parnell J, Mir SP, Amaro RE, Komives EA(2015). How the ankyrin and SOCS box protein, ASB9, binds to creatine kinase . Biochemistry.