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Hire Jacques F.

France

USD 159 /hr

Associate Professor | Microfluidics & Soft Matter Expert | Surface Chemistry • Imaging • Biotechnology

Profile Summary

I am an Associate Professor of Chemistry at Sorbonne Université and the École Normale Supérieure (Paris), and group leader at the Institut Pierre-Gilles de Gennes. With more than 15 years of experience in microfluidics, soft matter, and advanced imaging, I combine deep academic expertise with applied collaborations across the biotech, pharma, cosmetics, and materials industries. My research has led to several patents on functionalized emulsions and colloidal systems, including technologies licensed to industry, and I am also the cofounder of Quintessence Biotech, a deeptech startup developing lipid droplet–based immunotherapy tools. I have partnered with companies, providing solutions in drug delivery, emulsions and formulations, microfluidic nebulization, and assay development. I bring strong hands-on expertise in surface chemistry (wettability, coatings, interfacial energy control), microfluidic chip design (droplet generation, trapping, prototyping), and imaging/data analysis (confocal microscopy, FRET, high-content analysis, Python/Napari/ImageJ pipelines). I am also experienced in flow cytometry integration and in developing assays for immune cell phenotyping, microbial oil degradation, and bioremediation.

Subject Matter Expertise

• ☆ Microscopy
• ☆ Light Microscopy
• ☆ Microfluidics

Services

• Research
• Consulting
• Product Development

Research Feasibility Study, Technology Scouting, Gap Analysis, Gray Literature Search, Scientific and Technical Research, Systematic Literature Review

Consulting Operations Consulting, Scientific and Technical Consulting

Product Development Formulation, Concept Development, Prototyping, Reverse Engineering, Device Fabrication

Work Experience

Associate Professor

Sorbonne Université

September 2009 - Present

Maître de Conférences

Ecole Normale Supérieure, PSL University, Département de Chimie

September 2009 - Present

Education

Habilitation à Diriger des Recherches (Faculty of Chemistry)

Sorbonne Université

June 2017 - Present

PhD in Chemistry (ESPCI - LCMD)

Université Pierre et Marie Curie

September 2002 - September 2006

Master's degree - Soft and Condensed Matter

Université Pierre et Marie Curie

September 2001 - September 2002

Ingénieur

ESPCI-ParisTech

September 1998 - September 2002

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Jacques Fattaccioli, Lixin Huang, Rogério Lopes Dos Santos, Sid Labdi, Guillaume Lamour, Olek Maciejak, Michel Malo, John Manzi, Martin Lenz, Clément Campillo (2025). A Microfluidic Platform for Actin‐Based Membrane Remodeling Reveals the Stabilizing Role of Branched Actin Networks on Lipid Microdomains . Small Science.

Jacques Fattaccioli, Léa Bogdziewiez, Rik Froeling, Patricia Schöppl, Jeanne Juquel, Ioanna Antoniadi, Vladimìr Skalický, Ambroise Mathey, Joris Sprakel, Stéphane Verger (2025). The Q‐Warg Pipeline: A Robust and Versatile Workflow for Quantitative Analysis of Protoplast Culture Conditions . Plant Direct.

Jacques Fattaccioli, Nicolas Ruyssen, Gabriel Fina, Rachele Allena, Marie-Caroline Jullien (2025). Using lateral dispersion to optimise microfluidic trap array efficiency . Computers & Fluids.

Jacques Fattaccioli, Benjamin Cocom-Chan, Hamed Khakzad, Mahamadou Konate, Daniel Isui Aguilar, Chakir Bello, Cesar Valencia-Gallardo, Yosra Zarrouk, Alain Mauviel, Delphine Javelaud, et al. (2024). IpaA reveals distinct modes of vinculin activation duringShigellainvasion and cell-matrix adhesion . Life Science Alliance.

Jacques Fattaccioli, Sophie Michelis, Chiara Pompili, Florence Niedergang, Blaise Dumat, Jean-Maurice Mallet (2024). FRET-Sensing of Multivalent Protein Binding at the Interface of Biomimetic Microparticles Functionalized with Fluorescent Glycolipids . ACS Applied Materials & Interfaces.

M. Prasad, N. Obana, S.-Z. Lin, S. Zhao, K. Sakai, C. Blanch-Mercader, J. Prost, N. Nomura, J.-F. Rupprecht, J. Fattaccioli, et al. (2023). Alcanivorax borkumensis biofilms enhance oil degradation by interfacial tubulation . Science.

M. Prasad, N. Obana, S.-Z. Lin, S. Zhao, K. Sakai, C. Blanch-Mercader, J. Prost, N. Nomura, J.-F. Rupprecht, J. Fattaccioli, et al. (2023). Alcanivorax borkumensis biofilms enhance oil degradation by interfacial tubulation . Science.

Jacques Fattaccioli, Léa Pinon, Nicolas Ruyssen, Judith Pineau, Olivier Mesdjian, Damien Cuvelier, Anna Chipont, Rachele Allena, Coralie L. Guerin, Sophie Asnacios, et al. (2022). Phenotyping polarization dynamics of immune cells using a lipid droplet-cell pairing microfluidic platform . Cell Reports Methods.

O. Mesdjian, N. Ruyssen, M.-C. Jullien, R. Allena, J. Fattaccioli(2021). Enhancing the capture efficiency and homogeneity of single-layer flow-through trapping microfluidic devices using oblique hydrodynamic streams . Microfluidics and Nanofluidics. 25. (11). Springer Science and Business Media {LLC}

Jacques Fattaccioli, Kaori Sakai, Florence Charlot, Thomas Le Saux, Sandrine Bonhomme, Fabien Nogué, Jean-Christophe Palauqui(2019). Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplasts development and physiology . Plant Methods. 15. (1). Springer Science and Business Media {LLC}

Jacques Fattaccioli, Blaise Dumat, Lorraine Montel, Léa Pinon, Pascal Matton, Laurent Cattiaux, Jean-Maurice Mallet(2019). Mannose-Coated Fluorescent Lipid Microparticles for Specific Cellular Targeting and Internalization via Glycoreceptor-Induced Phagocytosis . ACS Applied Bio Materials. 2. (11). p. 5118--5126. American Chemical Society ({ACS})

Jacques Fattaccioli, Lorraine Montel, Léa Pinon(2019). A Multiparametric and High-Throughput Assay to Quantify the Influence of Target Size on Phagocytosis . Biophysical Journal. 117. (3). p. 408--419. Elsevier {BV}

Jacques Fattaccioli, Clotilde Vié, Philippe Jacq(2019). Introduction to Droplet-Based Millifluidic Chemistry Using a Macroscopic-Droplet Generator . Journal of Chemical Education. 96. (4). p. 797--800. American Chemical Society ({ACS})

Jacques Fattaccioli, Clotilde Vié, Philippe Jacq(2019). Introduction to Droplet-Based Millifluidic Chemistry Using a Macroscopic-Droplet Generator . Journal of Chemical Education. 96. (4). p. 797--800. American Chemical Society ({ACS})

Jacques Fattaccioli, Manoj Prasad, Nozomu Obana, Kaori Sakai, Toshiki Nagakubo, Shun Miyazaki, Masanori Toyofuku, Nobuhiko Nomura, Andrew S. Utada (2019). Point Mutations Lead to Increased Levels of c-di-GMP and Phenotypic Changes to the Colony Biofilm Morphology in <i>Alcanivorax borkumensis</i> SK2 . Microbes and Environments.

L. Pinon, L. Montel, O. Mesdjian, M. Bernard, A. Michel, C. Ménager, J. Fattaccioli(2018). Kinetically Enhanced Fabrication of Homogeneous Biomimetic and Functional Emulsion Droplets . Langmuir. 34. (50). p. 15319--15326. American Chemical Society ({ACS})

Jacques Fattaccioli, Francois-Marie Allioux, Pankaj Kapruwan, Nicholas Milne, Lingxue Kong, Yong Chen, Ludovic F. Dumée(2018). Electro-capture of heavy metal ions with carbon cloth integrated microfluidic devices . Separation and Purification Technology. 194. p. 26--32. Elsevier {BV}

L. Pinon, L. Montel, O. Mesdjian, M. Bernard, A. Michel, C. Ménager, J. Fattaccioli(2018). Kinetically Enhanced Fabrication of Homogeneous Biomimetic and Functional Emulsion Droplets . Langmuir. American Chemical Society ({ACS})

Jacques Fattaccioli, Sandrine Quignard, Ghislaine Frébourg, Yong Chen(2016). Nanometric emulsions encapsulating solid particles as alternative carriers for intracellular delivery . Nanomedicine. 11. (16). p. 2059--2072. Future Medicine Ltd

D. Molino, S. Quignard, C. Gruget, F. Pincet, Y. Chen, M. Piel, J. Fattaccioli(2016). On-Chip Quantitative Measurement of Mechanical Stresses During Cell Migration with Emulsion Droplets . Scientific Reports. 6. (1). Springer Nature

Jacques Fattaccioli, Olivier Mesdjian, Yong Chen(2016). Luminescent and absorptive metal-coated emulsions for micro-velocimetry . Microelectronic Engineering. 158. p. 69--74. Elsevier {BV}

Jacques Fattaccioli, Kalthoum Ben M'Barek, Diana Molino, Sandrine Quignard, Marie-Aude Plamont, Yong Chen, Philippe Chavrier(2015). Phagocytosis of immunoglobulin-coated emulsion droplets . Biomaterials. 51. p. 270--277. Elsevier {BV}

Jacques Fattaccioli, Sandrine Quignard, Marco d'Ischia, Yong Chen(2014). Ultraviolet-Induced Fluorescence of Polydopamine-Coated Emulsion Droplets . ChemPlusChem. 79. (9). p. 1254--1257. Wiley-Blackwell

Jacques Fattaccioli, Clothilde Longuet, Ayako Yamada, Yong Chen, Damien Baigl(2014). Spatially-controlled protein crystallization in microfluidic chambers . Journal of Crystal Growth. 386. p. 179--182. Elsevier {BV}

Jacques Fattaccioli, Giovanni Marco Nocera, Kalthoum Ben M'Barek, Dario Giovanni Bazzoli, Guillaume Fraux, Morgane Bontems-Van Heijenoort, Jeannette Chokki, Sonia Georgeault, Yong Chen(2014). Fluorescent microparticles fabricated through chemical coating of O/W emulsion droplets with a thin metallic film . RSC Advances. 4. (23). p. 11564. Royal Society of Chemistry ({RSC})

Jacques Fattaccioli, Jongho Park, Hiroyuki Fujita, Beomjoon Kim(2012). Fabrication of aluminum/alumina patterns using localized anodization of aluminum . International Journal of Precision Engineering and Manufacturing. 13. (5). p. 765--770. Springer Nature

Jacques Fattaccioli, Céline Bottier, Mehmet C. Tarhan, Ryuji Yokokawa, Fabrice O. Morin, Beomjoon Kim, Dominique Collard, Hiroyuki Fujita(2009). Active transport of oil droplets along oriented microtubules by kinesin molecular motors . Lab on a Chip. 9. (12). p. 1694. Royal Society of Chemistry ({RSC})

Jacques Fattaccioli, Jean Baudry, Jean-Daniel Émerard, Emanuel Bertrand, Cécile Goubault, Nelly Henry, Jérôme Bibette(2009). Size and fluorescence measurements of individual droplets by flow cytometry . Soft Matter. 5. (11). p. 2232. Royal Society of Chemistry ({RSC})

Jacques Fattaccioli, Jean Baudry, Nelly Henry, Francoise Brochard-Wyart, Jérôme Bibette(2008). Specific wetting probed with biomimetic emulsion droplets . Soft Matter. 4. (12). p. 2434. Royal Society of Chemistry ({RSC})

Jacques Fattaccioli, Swapan K. Mandal, Nicolas Lequeux, Benjamin Rotenberg, Marc Tramier, Jerome Bibette, Benoit Dubertret(2005). Encapsulation of Magnetic and Fluorescent Nanoparticles in Emulsion Droplets . Langmuir. 21. (9). p. 4175--4179. American Chemical Society ({ACS})

PREPRINT

Jacques Fattaccioli, Léa Bogdziewiez, Rik Froeling, Patricia Schoppl, Jeanne Juquel, Ioanna Antoniadi, Vladimìr Skalický, Ambroise Mathey, Joris Sprakel, Stéphane Verger (2025). The Q-Warg Pipeline: A Robust and Versatile Workflow for Quantitative Analysis of Protoplast Culture Conditions .

Jacques FATTACCIOLI, ChaoHe HU, Estelle LU, Lucie LACOUR, Nicolas DELSUC, Bruno Bresson, Jean-Maurice MALLET (2024). Shaping, Degradation And Drug Release Of Biosourced Particles Made From Acrylated Vegetable Oils .

Alcanivorax borkumensisBiofilms Enhance Oil Degradation By Interfacial Tubulation <head> <META HTTP-EQUIV="Refresh" CONTENT="0;URL=/servlet/useragent"> </head> .

Jacques Fattaccioli, Judith Pineau, L&#233;a Pinon, Olivier Mesdjian, Ana-Maria Lennon Dum&#233;nil, Paolo Pierobon (2022). Microtubules restrict F-actin polymerization to the immune synapse via GEF-H1 to maintain polarity in lymphocytes .

Jacques Fattaccioli, L&#233;a Pinon, Nicolas Ruyssen, Judith Pineau, Olivier Mesdjian, Damien Cuvelier, Rachele Allena, Sophie Asnacios, Atef Asnacios, Paolo Pierobon(2021). Onset and kinetics of B cell polarization depend on substrate mechanics and antigen concentration . Cold Spring Harbor Laboratory

Jacques Fattaccioli, Clotilde Vi&#233;, philippe jacq (2018). An introduction to digital microfluidic concepts in chemistry using a macroscopic droplet generator .

BOOK CHAPTER

Jacques Fattaccioli, Judith Pineau, L&#233;a Pinon, Paolo Pierobon (2023). Functionalized Lipid Droplets and Microfluidics Approach to Study Immune Cell Polarity In Vitro . The Immune Synapse.

OTHER

K. Sakai, F. Charlot, T. Le Saux, S. Bonhomme, F. Nogu&#233;, J.C. Palauqui, J. Fattaccioli(2019). Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplasts development and physiology . Cold Spring Harbor Laboratory

K. Sakai, F. Charlot, T. Le Saux, S. Bonhomme, F. Nogu&#233;, J.C. Palauqui, J. Fattaccioli(2019). Design of a comprehensive microfluidic and microscopic toolbox for the ultra-wide spatio-temporal study of plant protoplasts development and physiology . Cold Spring Harbor Laboratory

CONFERENCE PAPER

S. Akiyama, Y. T. Cheng, J. Fattaccioli, N. Takama, P. Low, C. Bergaud, B. J. Kim(2009). Surface-Temperature Control of Silicon Nanowires in Dry and Liquid Conditions . 2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems. {IEEE}

J. Fattaccioli, A. Ikeda, J.G. Kim, N. Takama, B.J. Kim(2009). Visual Observation of PDMS Tip in Liquid Microcontact Printing . 2009 IEEE 22nd International Conference on Micro Electro Mechanical Systems. {IEEE}

C. Bottier, M.C. Tarhan, J. Fattaccioli, F.O. Morin, B.J. Kim, H. Fujita(2008). Direct transportation and electrofusion of oil droplets in a microfluidic device . 2008 IEEE 21st International Conference on Micro Electro Mechanical Systems. {IEEE}