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Hire Dr. Jorge G.
Spain

Bioinformatician with 10 years of experience

Profile Summary
Subject Matter Expertise
Services
Data & AI Predictive Modeling, Statistical Analysis, Algorithm Design-Non ML
Work Experience

Investigador Bioinformático

Fundación La princesa

January 2022 - Present

Education

PhD Biomedical Sciences

Universidad de Oviedo

January 2006 - January 2012

Certifications
  • Certification details not provided.
Publications
PREPRINT
Gonzalo Soria-Alcaide, Gonzalo García-Aguilera, Marta Portasany-Rodriguez, Jaanam Lalchandani, África González-Murillo, Elena G. Sánchez, Cristina Saiz-Ladera, Manuel Ramírez-Orellana, Jorge Garcia-Martinez (2025). CROCKETA: An automated framework for comprehensive multi-omic analysis of gene expression and clonotype immune repertoire at a single-cell level .
Francisca Molina-Jiménez, Lola Ugalde-Triviño, Laura Arias-González, Carlos Relaño-Rupérez, Sergio Casabona, José Andrés Moreno-Monteagudo, María Teresa Pérez-Fernández, Verónica Martín-Domínguez, Jennifer Fernández-Pacheco, Emilio José Laserna-Mendieta, et al. (2023). Proton pump Inhibitor effect on esophageal protein signature of eosinophilic esophagitis, prediction and evaluation of treatment response .
Jose Luis Cabrera-Alarcon, Jose Antonio Enriquez, Jorge Garcia Martinez, Fátima Sánchez-Cabo (2020). Variant pathogenic prediction by locus variability, the importance of the last picture of evolution .
JOURNAL ARTICLE
June Iriondo, Ana Gómez, Josune Zubicaray, Jorge Garcia-Martinez, Lorea Abad, Carmen Matesanz, Reyes Giménez, Almudena Galán, Alejandro Sanz, Elena Sebastián, et al. (2024). Optical Genome Mapping as a New Tool to Overcome Conventional Cytogenetics Limitations in Patients with Bone Marrow Failure . Genes.
June Iriondo, Ana Gómez, Josune Zubicaray, Jorge Garcia-Martinez, Lorea Abad, Carmen Matesanz, Reyes Giménez, Almudena Galán, Alejandro Sanz, Elena Sebastián, et al. (2024). Optical Genome Mapping as a New Tool to Overcome Conventional Cytogenetics Limitations in Patients with Bone Marrow Failure . Genes.
García-García L, G Sánchez E, Ivanova M, Pastora K, Alcántara-Sánchez C, García-Martínez J, Martín-Antonio B, Ramírez M, González-Murillo Á (2024). Choosing T-cell sources determines CAR-T cell activity in neuroblastoma . Frontiers in immunology.
García-García, L., G. Sánchez, E., Ivanova, M., Pastora, K., Alcántara-Sánchez, C., García-Martínez, J., Martín-Antonio, B., Ramírez, M., González-Murillo, Á.(2024). Choosing T-cell sources determines CAR-T cell activity in neuroblastoma . Frontiers in Immunology. 15.
Iriondo, J., Gómez, A., Zubicaray, J., Garcia-Martinez, J., Abad, L., Matesanz, C., Giménez, R., Galán, A., Sanz, A., Sebastián, E., et al.(2024). Optical Genome Mapping as a New Tool to Overcome Conventional Cytogenetics Limitations in Patients with Bone Marrow Failure . Genes. 15. (5).
E. Muñoz‐Aceituno, B. Butrón‐Bris, M. C. Ovejero‐Benito, A. Sahuquillo‐Torralba, O. Baniandrés Rodríguez, E. Herrera‐Acosta, R. Rivera‐Diaz, M. Ferran, J. L. Sánchez‐Carazo, J. Riera‐Monroig, et al. (2023). Pharmacogenetic biomarkers for secukinumab response in psoriasis patients in real‐life clinical practice . Journal of the European Academy of Dermatology and Venereology.
Pablo Velasco, Francisco Bautista, Alba Rubio, Yurena Aguilar, Susana Rives, Jose L. Dapena, Antonio Pérez, Manuel Ramirez, Cristina Saiz-Ladera, Elisa Izquierdo, et al. (2023). The relapsed acute lymphoblastic leukemia network (ReALLNet): a multidisciplinary project from the spanish society of pediatric hematology and oncology (SEHOP) . Frontiers in Pediatrics.
Rubén Rodríguez, Isabel Gaivão, Leticia Aguado, Marta Espina, Jorge García, Pablo Martínez-Camblor, L. María Sierra (2023). The Comet Assay in Drosophila: A Tool to Study Interactions between DNA Repair Systems in DNA Damage Responses In Vivo and Ex Vivo . Cells.
Rubén Rodríguez, Isabel Gaivão, Leticia Aguado, Marta Espina, Jorge García, Pablo Martínez-Camblor, L. María Sierra (2023). The Comet Assay in Drosophila: A Tool to Study Interactions between DNA Repair Systems in DNA Damage Responses In Vivo and Ex Vivo . Cells.
García-Marín, R., Cabal, V.N., Fernández-Cedrón Bermejo, C., Riobello, C., Suárez-Fernández, L., Codina-Martínez, H., Navarro-García, A., Lorenzo-Guerra, S.L., García-Martínez, J., Vivanco, B., et al.(2023). A Novel External Auditory Canal Squamous Cell Carcinoma Cell Line Sensitive to CDK4/6 Inhibition . Otolaryngology - Head and Neck Surgery (United States). 168. (4). p. 729-737.
Muñoz-Aceituno, E., Butrón-Bris, B., Ovejero-Benito, M.C., Sahuquillo-Torralba, A., Baniandrés Rodríguez, O., Herrera-Acosta, E., Rivera-Diaz, R., Ferran, M., Sánchez-Carazo, J.L., Riera-Monroig, J., et al.(2023). Pharmacogenetic biomarkers for secukinumab response in psoriasis patients in real-life clinical practice . Journal of the European Academy of Dermatology and Venereology.
Alejandra Reolid, Antonio Sahuquillo-Torralba, Ancor Sanz-García, Rafael Botella-Estrada, Ester Muñoz-Aceituno, Mar Llamas-Velasco, Jorge García-Martínez, Esteban Daudén, Francisco Abad-Santos, María C. Ovejero-Benito (2022). CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis . Journal of Personalized Medicine.
Alejandra Reolid, Antonio Sahuquillo-Torralba, Ancor Sanz-García, Rafael Botella-Estrada, Ester Muñoz-Aceituno, Mar Llamas-Velasco, Jorge García-Martínez, Esteban Daudén, Francisco Abad-Santos, María C. Ovejero-Benito (2022). CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis . Journal of Personalized Medicine.
José Luis Cabrera-Alarcon 1, Jorge Garćıa Martinez 2, José Antonio Enŕıquez 3 4, Fátima Sánchez-Cabo 5(2022). Variant pathogenic prediction by locus variability: the importance of the current picture of evolution. Eur J Hum Genet .
(2022). A novel external auditory canal squamous cell carcinoma cell line sensitive to CDK4/6 inhibition. Otolaryngology-Head and Neck Surgery.
Reolid, A., Sahuquillo-Torralba, A., Sanz-García, A., Botella-Estrada, R., Muñoz-Aceituno, E., Llamas-Velasco, M., García-Martínez, J., Daudén, E., Abad-Santos, F., Ovejero-Benito, M.C.(2022). CNVs Associated with Different Clinical Phenotypes of Psoriasis and Anti-TNF-Induced Palmoplantar Pustulosis . Journal of Personalized Medicine. 12. (9).
Llamas-Velasco, M., Reolid, A., Sanz-García, A., Alonso-Guirado, L., García-Martínez, J., Sánchez-Jiménez, P., Muñoz-Aceituno, E., Daudén, E., Abad-Santos, F., Ovejero-Benito, M.C.(2021). Methylation in psoriasis. Does sex matter? . Journal of the European Academy of Dermatology and Venereology. 35. (2). p. e161-e163.
Sanz-García, A., Reolid, A., Fisas, L.H., Muñoz-Aceituno, E., Llamas-Velasco, M., Sahuquillo-Torralba, A., Botella-Estrada, R., García-Martínez, J., Navarro, R., Daudén, E., et al.(2021). DNA copy number variation associated with anti-tumour necrosis factor drug response and paradoxical psoriasiform reactions in patients with moderate-to-severe psoriasis . Acta Dermato-Venereologica. 101. (5).
Gomez-Cabrero, David, Walter, Stefan, Abugessaisa, Imad, Miñambres-Herraiz, Rebeca, Palomares, Lucia Bernad, Butcher, Lee, Erusalimsky, Jorge D, Garcia-Garcia, Francisco Jose, Carnicero, José, Hardman, Timothy C, et al.(2021). A robust machine learning framework to identify signatures for frailty: a nested case-control study in four aging European cohorts. Geroscience. 43. (3). p. 1317--1329. Springer International Publishing
Ancor Sanz-Garcia 1, Alej, ra Reolid, Laura H Fisas, Ester Muñoz-Aceituno, Mar Llamas-Velasco, Antonio Sahuquillo-Torralba, Rafael Botella-Estrada, Jorge Garćıa-Mart́ınez, Raquel Navarro, Esteban Daudén, Francisco Abad-Santos, Maria C Ovejero-Benito(2021). DNA Copy Number Variation Associated with Anti-tumour Necrosis Factor Drug Response and Paradoxical Psoriasiform Reactions in Patients with Moderate-to-severe Psoriasis. Acta Derm Venereol.
(2021). Telomere-based risk models for the early diagnosis of clinically significant prostate cancer. Prostate Cancer Prostatic Dis .
Nuria de Pedro 1, Maŕıa D́ıez 1, Irene Garćıa 1, Jorge Garćıa 1, Lissette Otero 1, Luis Fernández 1, Beatriz Garćıa 1, Rut González 1, Sara Rincón 1, Diego Pérez 1, Estefańıa Rodŕıguez 1, Enrique Segovia 1, Pilar Najarro 1(2020). Analytical Validation of Telomere Analysis Technology® for the High-Throughput Analysis of Multiple Telomere-Associated Variables. Biol Proced Online .
Bakker, Bjorn, Terra, Jorrit, Zhou, Lin, Racz, Emoke, Paljic, Sonja, Garcia-Martinez, Jorge, Oliveira, Vera, Bakker, Petra L, Spierings, Diana CJ, Jonkman, Marcel F, et al.(2018). Single cell DNA sequencing reveals distinct molecular types of basal cell carcinoma with unique transcriptome features. BioRxiv. p. 492199. Cold Spring Harbor Laboratory
De Pedro, N, Estrada, JC, Chiesa, M, Diez, M, Garcia, I, González, R, Garcia, B, Garćıa, J, Esteban, L, Otero, L, et al.(2017). Telomere associated variables and their potential in CLL prognosis. Annals of Oncology. 28. p. v26. Elsevier
Garcia-Martinez, Jorge, Bakker, Bjorn, Schukken, Klaske M, Simon, Judith E, Foijer, Floris(2016). Aneuploidy in stem cells. World journal of stem cells. 8. (6). p. 216--222. Baishideng Publishing Group Inc.
Garcia Martinez, Jorge, Garćıa--Inclán, Cristina, Suárez, Carlos, Llorente, José L, Hermsen, Mario A(2015). DNA aneuploidy-specific therapy for head and neck squamous cell carcinoma. Head & Neck. 37. (6). p. 884--888.
Vázquez-Villa, F., García-Ocaña, M., Galván, J.A., García-Martínez, J., García-Pravia, C., Menéndez-Rodríguez, P., Rey, C.G.-D., Barneo-Serra, L., de los Toyos, J.R.(2015). COL11A1/(pro)collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression . Tumor Biology. 36. (4). p. 2213-2222.
Martínez, J.G., García-Inclán, C., Suárez, C., Llorente, J.L., Hermsen, M.A.(2015). DNA aneuploidy-specific therapy for head and neck squamous cell carcinoma . Head and Neck. 37. (6). p. 884-888.
Vázquez-Villa, Fern, o, Garćıa-Ocaña, Marcos, Galván, José A, Garćıa-Mart́ınez, Jorge, Garćıa-Pravia, Carmen, Menéndez-Rodŕıguez, Primitiva, Rey, Carmen González-del, Barneo-Serra, Luis, de Los Toyos, Juan R(2015). COL11A1/(pro) collagen 11A1 expression is a remarkable biomarker of human invasive carcinoma-associated stromal cells and carcinoma progression. Tumor Biology. 36. (4). p. 2213--2222. Springer Netherlands
Galván, José A, Garćıa-Mart́ınez, Jorge, Vázquez-Villa, Fern, o, Garćıa-Ocaña, Marcos, Garćıa-Pravia, Carmen, Menéndez-Rodŕıguez, Primitiva, González-del Rey, Carmen, Barneo-Serra, Luis, de los Toyos, Juan R(2014). Validation of COL11A1/procollagen 11A1 expression in TGF-$β$1-activated immortalised human mesenchymal cells and in stromal cells of human colon adenocarcinoma. BMC cancer. 14. (1). p. 1--12. BioMed Central
Galván, J.A., García-Martínez, J., Vázquez-Villa, F., García-Ocaña, M., García-Pravia, C., Menéndez-Rodríguez, P., González-del Rey, C., Barneo-Serra, L., de los Toyos, J.R.(2014). Validation of COL11A1/procollagen 11A1 expression in TGF-β1-activated immortalised human mesenchymal cells and in stromal cells of human colon adenocarcinoma . BMC Cancer. 14. (1).
Fernández Garćıa, Maŕıa Teresa, Vázquez Villa, José Fern, o, Garćıa Mart́ınez, J, Sánchez Pitiot, Marta, Centeno Ramos, Irene, Fern, o Maćıas, Ester, Porrero Guerrero, Belén, López Arévalo, Camilo Andrés, et al.(2014). Pro-Col11A1 expression in human peritumoral fibroblasts in model of orthotopic human pancreatic carcinoma xenograft. British Journal of Surgery.
Coca--Pelaz, Andrés, Llorente--Pendás, Jose Luis, Garćıa--Mart́ınez, Jorge, Vivanco--Allende, Blanca, Balb́ın, Milagros, Suárez, Carlos, Hermsen, Mario(2013). Medullary thyroid carcinoma and 2q37 deletion in a patient with nevoid basal cell carcinoma syndrome: Clinical description and genetic analysis. Head & neck. 35. (5). p. E147--E152. Wiley Subscription Services, Inc., A Wiley Company Hoboken
Coca-Pelaz, A., Llorente-Pendás, J.L., García-Martínez, J., Vivanco-Allende, B., Balbín, M., Suárez, C., Hermsen, M.(2013). Medullary thyroid carcinoma and 2q37 deletion in a patient with nevoid basal cell carcinoma syndrome: Clinical description and genetic analysis . Head and Neck. 35. (5).
Mart́ınez, Jorge Garćıa, Pérez-Escuredo, Jhudit, Garćıa-Carracedo, Dario, Alonso-Guervós, Marta, Suárez-Nieto, Carlos, Llorente-Pendás, José Luis, Álvarez-Marcos, César, Hermsen, Mario(2012). Analysis of microsatellite instability in laryngeal squamous cell carcinoma. Acta Otorrinolaringologica (English Edition). 63. (2). p. 79--84. Elsevier Doyma
Martínez, J.G., Pérez-Escuredo, J., García-Carracedo, D., Alonso-Guervós, M., Suárez-Nieto, C., Llorente-Pendás, J.L., Álvarez-Marcos, C., Hermsen, M.(2012). Erratum to " Analysis of microsatellite instability in laryngeal squamous cell carcinoma",Fe de errores de " Análisis de la inestabilidad de microsatélites en el carcinoma escamoso de laringe" . Acta Otorrinolaringologica Espanola. 63. (3). p. 246-247.
Mart́ınez, Jorge Garćıa, Pérez-Escuredo, Jhudit, Castro-Santos, Patricia, Marcos, César Álvarez, Pendás, José Luis Llorente, Fraga, Mario F, Hermsen, Mario A(2012). Hypomethylation of LINE-1, and not centromeric SAT-$α$, is associated with centromeric instability in head and neck squamous cell carcinoma. Cellular Oncology. 35. (4). p. 259--267. Springer Netherlands
García Martínez, J., Pérez-Escuredo, J., García-Carracedo, D., Alonso-Guervós, M., Suárez-Nieto, C., Llorente-Pendás, J.L., Álvarez-Marcos, C., Hermsen, M.(2012). Analysis of microsatellite instability in laryngeal squamous cell carcinoma,Análisis de la inestabilidad de microsatélites en el carcinoma escamoso de laringe . Acta Otorrinolaringologica Espanola. 63. (2). p. 79-84.
Pérez-Escuredo, J., Martínez, J.G., Vivanco, B., Marcos, C.Á., Suárez, C., Llorente, J.L., Hermsen, M.A.(2012). Wood dust-related mutational profile of TP53 in intestinal-type sinonasal adenocarcinoma . Human Pathology. 43. (11). p. 1894-1901.
Martínez, J.G., Pérez-Escuredo, J., Castro-Santos, P., Marcos, C.A., Pendás, J.L.L., Fraga, M.F., Hermsen, M.A.(2012). Hypomethylation of LINE-1, and not centromeric SAT-a, is associated with centromeric instability in head and neck squamous cell carcinoma . Cellular Oncology. 35. (4). p. 259-267.
Martínez, J.G., Pérez-Escuredo, J., Llorente, J.L., Suárez, C., Hermsen, M.A.(2012). Localization of centromeric breaks in head and neck squamous cell carcinoma . Cancer Genetics. 205. (12). p. 622-629.
Pérez-Escuredo, Jhudit, Mart́ınez, Jorge Garćıa, Vivanco, Blanca, Marcos, César Álvarez, Suárez, Carlos, Llorente, José Luis, Hermsen, Mario A(2012). Wood dust--related mutational profile of TP53 in intestinal-type sinonasal adenocarcinoma. Human pathology. 43. (11). p. 1894--1901. WB Saunders
Garćıa Mart́ınez, Jorge, Pérez Escuredo, Jhudit, Castro Santos, Patricia, Álvarez Marcos, César Antonio, Llorente Pendás, José Luis, Fernández Fraga, Mario, Hermsen, Mario(2012). Centromeric instability in head and neck squamous cell carcinoma. Cellular Oncology.
Mart́ınez, Jorge Garćıa, Pérez-Escuredo, Jhudit, Llorente, José Luis, Suárez, Carlos, Hermsen, Mario A(2012). Localization of centromeric breaks in head and neck squamous cell carcinoma. Cancer genetics. 205. (12). p. 622--629. Elsevier
Pérez-Escuredo, Jhudit, Garćıa Mart́ınez, Jorge, Garćıa-Inclán, Cristina, Vivanco, Blanca, Costales, Maŕıa, Álvarez Marcos, César, Llorente, José Luis, Hermsen, Mario A(2011). Establishment and genetic characterization of an immortal tumor cell line derived from intestinal-type sinonasal adenocarcinoma. Cellular Oncology. 34. (1). p. 23--31. Springer Netherlands
Pérez-Escuredo, J., Martínez, J.G., García-Inclán, C., Vivanco, B., Costales, M., Marcos, C.A., Llorente, J.L., Hermsen, M.A.(2011). Establishment and genetic characterization of an immortal tumor cell line derived from intestinal-type sinonasal adenocarcinoma . Cellular Oncology. 34. (1). p. 23-31.
Mart́ınez, Jorge Garćıa, Pérez-Escuredo, Jhudit, López, Fern, o, Suárez, Carlos, Álvarez-Marcos, César, Llorente, José Luis, Hermsen, Mario A(2009). Microsatellite instability analysis of sinonasal carcinomas. Otolaryngology—Head and Neck Surgery. 140. (1). p. 55--60. SAGE Publications Sage CA: Los Angeles, CA
Martínez, J.G., Pérez-Escuredo, J., López, F., Suárez, C., Álvarez-Marcos, C., Llorente, J.L., Hermsen, M.A.(2009). Microsatellite instability analysis of sinonasal carcinomas . Otolaryngology - Head and Neck Surgery. 140. (1). p. 55-60.
Martinez, Jorge Garcia(2009). Implication of Defects in MMR in Sinonasal Carcinomas. Skull Base. 19. (01). p. A179.
Hermsen, Mario, Pérez Escuredo, Jhudit, Llorente Pendás, José Luis, Garćıa Mart́ınez, Jorge, Álvarez Marcos, César Antonio, Suárez Nieto, Carlos(2008). Recurrent genetic changes in intestinal-type sinonasal adenocarcinoma. Cellular Oncology.
Escuredo, Jhudit Pérez, Llorente, José Luis, Melón, Santiago, de Oña, Maŕıa, Mart́ınez, Jorge Garćıa, Marcos, César Álvarez, Hermsen, Mario(2007). Las infecciones por virus herpes simplex, Epstein-Barr, varicela zoster, papiloma humano, citomegalovirus o adenovirus no tienen relación con los adenocarcinomas nasosinusales. Acta Otorrinolaringológica Española. 58. (7). p. 311--315. Elsevier Doyma
OTHER
Molina-Jiménez, F., Ugalde-Triviño, L., Arias-González, L., Relaño-Rupérez, C., Casabona, S., Moreno-Monteagudo, J.A., Pérez-Fernández, M.T., Martín-Domínguez, V., Fernández-Pacheco, J., Laserna-Mendieta, E.J., et al.(2023). Proton pump Inhibitor effect on esophageal protein signature of eosinophilic esophagitis, prediction and evaluation of treatment response . medRxiv.
JL Cabrera-Alarcon, J Garcia-Martinez(2018). Variant pathogenic prediction models VSRFM and VSRFM-s, the importance of splicing and allele frequency . Cold Spring Harbor Laboratory
CONFERENCE PAPER
Garcia, MJA, Alegre Amor, A, Baltasar, P, Loscertales, J, Hern, ez Rivas, JA, Martinez, R, Sanchez Godoy, P, De la Serna, J, Garcia Vela, JA, et al.(2017). CLINICAL VALIDATION STUDY OF THE VARIABLES ASSOCIATED WITH THE TELOMERS AS PROGNOSIS BIOMARKERS IN CLL. HAEMATOLOGICA. 102. p. 166--166.
Perez-Escuredo, J, Vivanco, B, Garcia Martinez, J, Fresno, F, Suarez, C, Llorente, J, Hermsen, M(2010). A ROLE FOR CHRONIC INFLAMMATION IN INTESTINAL-TYPE SINONASAL ADENOCARCINOMA. CELLULAR ONCOLOGY. 32. (3). p. 203--203.
Garcia Martinez, J, Perez-Escuredo, J, Vivanco, B, Fresno, F, Suarez, C, Llorente, J, Hermsen, M(2010). ESTABLISHMENT AND GENETIC CHARACTERIZATION OF AN IMMORTAL CELL LINE DERIVED FROM AN INTESTINAL-TYPE SINONASAL ADENOCARCINOMA. CELLULAR ONCOLOGY. 32. (3). p. 202--203.
DISSERTATION THESIS
Mart́ınez, Jorge Garćıa(2012). Genomic instability in head and neck squamous cell carcinoma. Focus on the centromere.