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Hire Dr. Irene S.

United Kingdom

USD 60 /hr

Senior scientist with 20 + years of experience in B-cell Immunobiology and extensive experience in the pharma industry

Profile Summary

I´m a Senior Scientist with a strong background in Translational Immunology. My main interest is the research and development of new strategies in Immunotherapy. I received my PhD degree in Biology from the University of Vigo (Spain) where I generated fully human monoclonal antibodies (mAbs) to human B cells using transgenic mice. Since 2004, I have developed my research career in both academia and industry. I was a post-doctoral fellow at UCL and Imperial College London, working in immunotherapy of Multiple Myeloma and antibody targeted photodynamic therapy of tumour vasculature, respectively. I joined UCB Pharma Ltd to develop a strategy to discover tumour-associated antigens from the natural anti-tumor B cell response. Prior to joining GSK in 2017, I worked as a senior scientist at Facundo Batista’s lab (CRUK/Francis Crick Institute) to develop an in vitro activation strategy to generate therapeutic mAbs from healthy individuals which resulted in the creation of the start-up BliNK Therapeutics. As a scientific investigator at GSK, I have focused on B cell biology and its applications in therapeutic antibody discovery and target discovery and validation. I have been responsible for the evaluation and implementation of microfluidic platforms for high-throughput single B cell screening and I have also led antibody discovery campaigns. During a secondment on the Immunology Research Unit I have developed a platform to integrate single B cell transcriptomics with antibody repertoire and binding analyses, a powerful tool not only to identity potential therapeutic targets in autoimmune diseases and cancer, but also to accelerate vaccine research and antibody discovery.

Subject Matter Expertise

• ☆ Separation & Purification
• ☆ Biochemistry
• ☆ Immunoassay
• ☆ Molecular Biology
• ☆ Monoclonal Antibody Production
• ☆ Biotechnology & Bioengineering
• ☆ Antibody Engineering
• ☆ Pharmaceutical Sciences
• ☆ Drug Development
• ☆ Vaccine Development
• ☆ Immunotherapy

Services

• Consulting
• Product Development

Work Experience

Senior Scientific Officer

Cancer Research UK

June 2011 - Present

Scientific investigator

GlaxoSmithKline ( GSK)

April 2017 - April 2024

Senior Scientific Officer

Cancer Research UK

May 2011 - September 2016

Research Associate

Imperial College London

December 2008 - May 2011

RESEARCH ASSOCIATE

Imperial College London

December 2008 - April 2011

Research Scientist

UCB Celltech

August 2006 - November 2008

RESEARCH SCIENTIST

UCB PHARMA LTD

July 2006 - November 2008

RESEARCH ASSOCIATE

UNIVERSITY COLLEGE OF LONDON

February 2004 - February 2006

Research Associate

University College London

February 2004 - February 2006

PhD STUDENT

University of Vigo

September 1997 - June 2003

Education

PhD (Immunology, Genetics and Biochemisry)

Universidade de Vigo

October 1997 - July 2003

BIOLOGY

Universidade de Santiago de Compostela

October 1990 - July 1995

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Johdi NA, Harman R, Sanjuan I, Kousparou C, Courtenay-Luck N, Deonarain MP, Protein expression and purification, 2013, vol. 88, no. 1, pp. 157-163 .

Díaz B, Sanjuan I, Gambón F, Loureiro C, Magadán S, González-Fernández A, Cancer immunology, immunotherapy : CII, 2009, vol. 58, no. 3, pp. 351-360 .

Suárez E, Magadán S, Sanjuán I, Valladares M, Molina A, Gambón F, Díaz-Espada F, González-Fernández A, Molecular immunology, 2006, vol. 43, no. 11, pp. 1827-1835 .

Rew SB, Peggs K, Sanjuan I, Pizzey AR, Koishihara Y, Kawai S, Kosaka M, Ozaki S, Chain B, Yong KL, Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, vol. 11, no. 9, pp. 3377-3384 .

Molina A, Valladares M, Magadán S, Sancho D, Viedma F, Sanjuan I, Gambón F, Sánchez-Madrid F, González-Fernández A, Journal of immunological methods, 2003, vol. 282, no. 1-2, pp. 147-158 .

Magadán S, Valladares M, Suarez E, Sanjuán I, Molina A, Ayling C, Davies SL, Zou X, Williams GT, Neuberger MS, Brüggemann M, Gambón F, Diaz-Espada F, González-Fernandez A, BioTechniques, 2002, vol. 33, no. 3, pp. 680, 682, 684 passim .