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Hire Igor K.
United States
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Biomedical Scientist and Writer with 20+ years of experiance in research
Profile Summary
Subject Matter Expertise
Services
Writing
Medical Writing,
General Proofreading & Editing,
Translation
Research
Scientific and Technical Research,
Systematic Literature Review
Consulting
Scientific and Technical Consulting
Data & AI
Statistical Analysis,
Data Visualization,
Data Mining,
Data Processing
Product Development
Formulation
Work Experience
Research Associate III
HD Biosciences Co., Ltd.
2022 - 2024 ![]()
Postdoctoral Research Fellow
University of California, San Diego
2021 - 2022 ![]()
Research Associate
University of Colorado Anschutz Medical Campus
2019 - 2021 ![]()
Postdoctoral Research Fellow
New York Medical College
2017 - 2019 ![]()
Research Scientist
Taras Shevchenko National University of Kyiv
2016 - 2017 ![]()
Senior Research Scientist
Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine
2010 - 2016 ![]()
Research Scientist
Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine
2008 - 2010 ![]()
Junior Research Scientist
Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine
2005 - 2008 ![]()
Education
PhD (Pharmacology)
Institute of Pharmacology and Toxicology of the National Academy of Medical Sciences of Ukraine
2000 - 2005 ![]()
Specialist (Human and Animal Physiology )
Taras Shevchenko National University of Kyiv
1999 - 2000 ![]()
BSc (Human and Animal Physiology)
Taras Shevchenko National University of Kyiv
1996 - 1999 ![]()
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
I. V. Kizub (2023). Induced pluripotent stem cells for cardiovascular therapeutics: Progress and perspectives . Regulatory Mechanisms in Biosystems.
Dariia O. Dryn, Mariia I. Melnyk, Donal Melanaphy, Igor V. Kizub, Christopher D. Johnson, Alexander V. Zholos (2023). Bidirectional TRP/L Type Ca2+ Channel/RyR/BKCa Molecular and Functional Signaloplex in Vascular Smooth Muscles . Biomolecules.
Dariia O. Dryn, Mariia I. Melnyk, Donal Melanaphy, Igor V. Kizub, Christopher D. Johnson, Alexander V. Zholos (2023). Bidirectional TRP/L Type Ca<sup>2+</sup> Channel/RyR/BK<sub>Ca</sub> Molecular and Functional Signaloplex in Vascular Smooth Muscles . Biomolecules.
Kitagawa, A., Kizub, I., Jacob, C., Michael, K., D'Alessandro, A., Reisz, J.A., Grzybowski, M., Geurts, A.M., Rocic, P., Gupte, R., et al.(2020). CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight into Reduced Cardiovascular Risk Associated with Mediterranean G6PD Variant . Hypertension. p. 523-532.
Soloviev, A.I., Kizub, I.V.(2019). Mechanisms of vascular dysfunction evoked by ionizing radiation and possible targets for its pharmacological correction . Biochemical Pharmacology. 159. p. 121-139.
Ochi, R., Chettimada, S., Kizub, I., Gupte, S.A.(2018). Dehydroepiandrosterone inhibits I<sub>Ca,L</sub> and its window current in voltage-dependent and-independent mechanisms in arterial smooth muscle cells . American Journal of Physiology - Heart and Circulatory Physiology. 315. (6). p. H1602-H1613.
Igor Kizub(2017). Protein kinase C (PKC) involved in enhancement of α1-adrenoceptor-mediated responses of the main pulmonary artery in rats with diabetes mellitus . Regulatory Mechanisms in Biosystems. 8. (2). p. 287--292. Oles Honchar Dnipropetrovsk National University
The Role of TRPV4 Cation Channels in Regulation of Phenylephrine-Induced Contraction of Rat Pulmonary Artery Dryn D., Melnyk M., Kizub I., Hu H., Soloviev A., Zholos A. The role of TRPV4 cation channels in regulation of phenylephrine-induced contraction of rat pulmonary artery. Int J Phys Pathophys 2017; 8(2): 121–130 . International Journal of Physiology and Pathophysiology.
[THE ROLE OF TRPV4 CATION CHANNELS IN THE REGULATION OF PHENYLEPHRINE-INDUCED CONTRACTION OF RAT PULMONARY ARTER] Dryn D., Melnyk M., Kizub I., Hu H., Soloviev A., Zholos A. The role of TRPV4 cation channels in the regulation of phenylephrine-induced contraction of rat pulmonary artery. Fiziol Zhurn 2016; 62(2): 79–86. PMID: 29537229 . Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
[Protein kinase C participation in the mechanisms of vascular tone disturbance upon diabetes mellitus. Part 4] Kizub I., Kharchenko О., Kostiuk О., Ostapchenko L., Klymenko К., Soloviev А. Protein kinase C participation in mechanisms of vascular tone abnormality in diabetes mellitus. Part 4. Bulletin of Taras Shevchenko National University of Kyiv. Series: Problems of Physiological Functions Regulation 2016; 2(21): 61–66. [In Ukrainian] . Bulletin of Taras Shevchenko National University of Kyiv. Series: Problems of Physiological Functions Regulation.
Kizub, I.V., Lakhkar, A., Dhagia, V., Joshi, S.R., Jiang, H., Wolin, M.S., Falck, J.R., Koduru, S.R., Errabelli, R., Jacobs, E.R., et al.(2016). Involvement of gap junctions between smooth muscle cells in sustained hypoxic pulmonary vasoconstriction development: A potential role for 15-HETE and 20-HETE . American Journal of Physiology - Lung Cellular and Molecular Physiology. 310. (8). p. L772-L783.
[Interaction of TRPV4 and ВКСа channels in the regulation of vascular tone of rat pulmonary arteries] Dryn D., Melnyk M., Kizub I., Zholos A., Soloviev A. Interaction of TRPV4 and ВКСа channels in the regulation of vascular tone of rat pulmonary arteries. Pharmacol Drug Toxicol (Ukraine) 2015; 46(6): 58–63 . Pharmacology and Drug Toxicology (Kiev, Ukraine).
[Functional expression and role of TRPV4-channels in the regulation of the rat pulmonary artery vascular tone] Dryn D., Melnyk M., Kizub I., Zholos A., Soloviev A. Functional expression and role of TRPV4-channels in the regulation of the rat pulmonary artery vascular tone. Pharmacol Drug Toxicol (Ukraine) 2015; 45(4-5): 39–45 . Pharmacology and Drug Toxicology (Kiev, Ukraine).
Klymenko, K., Novokhatska, T., Kizub, I., Parshikov, A., Dosenko, V., Soloviev, A.(2014). PKC-δ Isozyme gene silencing restores vascular function in diabetic rats . Journal of Basic and Clinical Physiology and Pharmacology. 25. (4). p. 341-349.
Igor Kizub (2014). Protein kinase C and Rho-associated coiled-coil kinase in mechanisms of Ca2+ sensitization in diabetes-induced vascular smooth muscle hypercontractility . Austin Journal of Vascular Medicine.
Kizub, I.V., Klymenko, K.I., Soloviev, A.I.(2014). Protein kinase C in enhanced vascular tone in diabetes mellitus . International Journal of Cardiology. 174. (2). p. 230-242.
Strielkov, I.V., Kizub, I.V., Khromov, A.S., Soloviev, A.I.(2013). Evidence for the role of phosphatidylcholine-specific phospholipase C in sustained hypoxic pulmonary vasoconstriction . Vascular Pharmacology. 58. (4). p. 292-298.
Kizub, I.V., Strielkov, I.V., Shaifta, Y., Becker, S., Prieto-Lloret, J., Snetkov, V.A., Soloviev, A.I., Aaronson, P.I., Ward, J.P.T.(2013). Gap junctions support the sustained phase of hypoxic pulmonary vasoconstriction by facilitating calcium sensitization . Cardiovascular Research. 99. (3). p. 404-411.
Soloviev, A.I., Bondarenko, A.I., Kizub, I.V.(2012). Selective glycolysis blockade in guinea pig pulmonary artery and aorta reverses contractile and electrical responses to acute hypoxia . Vascular Pharmacology. 57. (2-4). p. 119-123.
Kizub, I.V., Pavlova, O.O., Ivanova, I.V., Soloviev, A.I.(2010). Protein kinase C-dependent inhibition of BKCa current in rat aorta smooth muscle cells following γ-irradiation . International Journal of Radiation Biology. 86. (4). p. 291-299.
Igor Kizub (2008). [Effect of ionising irradiation on outward potassium current in the aorta smooth muscle cells in rats: the role of protein kinase C]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
Igor Kizub (2007). [Modern conception of protein kinase C role in the vascular smooth muscles tone regulation]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
Soloviev, A.I., Tishkin, S.M., Zelensky, S.N., Ivanova, I.V., Kizub, I.V., Pavlova, A.A., Moreland, R.S.(2005). Ionizing radiation alters myofilament calcium sensitivity in vascular smooth muscle: Potential role of protein kinase C . American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 289. (3 58-3).
Igor Kizub(2003). Role of Glycolysis and Myoendothelial Gap Junctions in the Development of Hypoxic Pulmonary Vasoconstriction . Neurophysiology. 35. (3/4). p. 323. Springer Science and Business Media {LLC}
Igor Kizub (2003). [Effect of inhibition of glycolysis and myoendothelial electrical coupling on contractile responses of pulmonary artery and aorta during hypoxia in rats]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994).
BOOK CHAPTER
Igor Kizub, Andrii Rozhok, Ganna Bilousova (2023). Induced Pluripotent Stem Cells: Advances and Applications in Regenerative Medicine . Possibilities and Limitations in Current Translational Stem Cell Research.
CONFERENCE ABSTRACT
Igor Kizub(2019). Pharmacological Inhibition of Glucose‐6‐phosphate Dehydrogenase Produces Inhibition of L‐type Calcium Channel Current in Arterial Smooth Muscle Cells . The FASEB Journal. 33. (S1). Wiley
Igor Kizub(2015). Involvement of Gap Junctions Between Smooth Muscle Cells in The Sustained Hypoxic Pulmonary Vasoconstriction Development . The FASEB Journal. 29. (S1). Wiley