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Profile Details
Subject Matter Expertise
Services
Work Experience
Senior Research Fellow
University of Manchester
September 2014 - June 2016
Senior Research Fellow Pharmacometrics/Biostatistics/Systems Pharmacology
University of Manchester
September 2014 - June 2016
Senior PKPD Modeller
Physiomics
December 2012 - August 2014
Clinical Pharmaometrician
AstraZeneca
December 2010 - December 2012
Computational Modeller
AstraZeneca
December 2008 - December 2010
Post-doctoral Researcher
Cyclacl Ltd. & University of Dundee
December 2006 - December 2008
Education
Applied Mathematics PhD (Mathematics)
University of Manchester
September 2003 - November 2006
Applied Numerical Computing MSc (Mathematics)
University of Manchester
September 2002 - August 2003
Mathematics BSc (Mathematics)
UMIST
September 1999 - July 2002
Certifications
- Certification details not provided.
Publications
JOURNAL ARTICLE
Hitesh B. Mistry, James W.T. Yates (2019). Quantifying Preexisting Resistant and Persister Populations–Letter . Cancer Research.
Hitesh B. Mistry, Gabriel Helmlinger, Nidal Al-Huniti, Karthick Vishwanathan, James Yates(2019). Resistance models to {EGFR} inhibition and chemotherapy in non-small cell lung cancer via analysis of tumour size dynamics . Cancer Chemotherapy and Pharmacology. 84. (1). p. 51--60. Springer Science and Business Media {LLC}
Hitesh Mistry, Ahmed Salem, Ross A. Little, Ayşe Latif, Adam K. Featherstone, Muhammad Babur, Isabel Peset, Susan Cheung, Yvonne Watson, Victoria Tessyman, et al.(2019). Oxygen-enhanced {MRI} Is Feasible, Repeatable, and Detects Radiotherapy-induced Change in Hypoxia in Xenograft Models and in Patients with Non{\textendash}small Cell Lung Cancer . Clinical Cancer Research. 25. (13). p. 3818--3829. American Association for Cancer Research ({AACR})
(2019). A simple model of a growing tumour . PeerJ.
Salem A, Mistry H, Hatton M, Locke I, Monnet I, Blackhall F, Faivre-Finn C(2018). Association of Chemoradiotherapy With Outcomes Among Patients With Stage I to II vs Stage III Small Cell Lung Cancer: Secondary Analysis of a Randomized Clinical Trial . JAMA oncology.
Hague C, Beasley W, Dixon L, Gaito S, Garcez K, Green A, Lee LW, Maranzano M, McPartlin A, Mistry H, et al.(2018). Use of a novel atlas for muscles of mastication to reduce inter observer variability in head and neck radiotherapy contouring . Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
Levy A, Le Péchoux C, Mistry H, Martel-Lafay I, Bezjak A, Lerouge D, Padovani L, Taylor P, Faivre-Finn C(2018). Prophylactic Cranial Irradiation for Limited-Stage Small-Cell Lung Cancer Patients: Secondary Findings From the Prospective Randomized Phase 3 CONVERT Trial . Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
Christodoulou M, Blackhall F, Mistry H, Leylek A, Knegjens J, Remouchamps V, Martel-Lafay I, Farré N, Zwitter M, Lerouge D, et al.(2018). Compliance and Outcome of Elderly Patients Treated in the Concurrent Once-Daily Versus Twice-Daily Radiotherapy (CONVERT) Trial . Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
Arkwright PD, MacMahon J, Koplin J, Rajput S, Cross S, Fitzsimons R, Davidson N, Deshpande V, Rao N, Lumsden C, et al.(2018). Severity and threshold of peanut reactivity during hospital-based open oral food challenges: an international multi-center survey . Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.
Mistry HB(2018). QSP versus the rest: let the competition commence! . CPT: pharmacometrics & systems pharmacology.
Ali A, Hoyle A, Mistry H, Clarke NW(2018). The importance of non-regional lymph nodes in assigning risk in primary metastatic prostate cancer . BJU international.
Oates A, Lindsay S, Mistry H, Ortega F, McBain AJ(2018). Modelling antisepsis using defined populations of facultative and anaerobic wound pathogens grown in a basally perfused biofilm model . Biofouling.
Hitesh B. Mistry(2018). Complex versus simple models: ion-channel cardiac toxicity prediction . {PeerJ}. 6. p. e4352. {PeerJ}
E. Shawkat, H. Mistry, C. Chmiel, L. Webster, L. Chappell, E.D. Johnstone, J.E. Myers(2018). The Effect Of Labetalol And Nifedipine {MR} On Blood Pressure In Women With Chronic Hypertension In Pregnancy . Pregnancy Hypertension. Elsevier {BV}
Hitesh B. Mistry, David Orrell, Raluca Eftimie(2017). Model based analysis of the heterogeneity in the tumour size dynamics differentiates vemurafenib, dabrafenib and trametinib in metastatic melanoma . Cancer Chemotherapy and Pharmacology. Springer Nature
(2017). On the relationship between tumour growth rate and survival in non-small cell lung cancer . PeerJ.
Hitesh Mistry, Ahmed Salem, Alison Backen, Clare Hodgson, Pek Koh, Emma Dean, Lynsey Priest, Kate Haslett, Ioannis Trigonis, Alan Jackson, et al.(2017). Cell-death, inflammation, tumor-burden and proliferation blood biomarkers predict lung cancer radiotherapy response and correlate with tumor volume and proliferation imaging . Clinical Lung Cancer. Elsevier {BV}
(2016). Systems Pharmacology Modeling of Prostate-Specific Antigen in Patients With Prostate Cancer Treated With an Androgen Receptor Antagonist and Down-Regulator . CPT: Pharmacometrics & Systems Pharmacology.
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Hitesh Mistry, Phil Chapman(2018). Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategy . {PeerJ}
Hitesh Mistry, Phil Chapman (2018). Simulation of cancer cell line pharmacogenomics data to optimise experimental design and analysis strategy .
Hitesh B. Mistry(2017). A cautionary tale on using tumour growth rate to predict survival . Cold Spring Harbor Laboratory