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Hire Herve T.

France

USD 100 /hr

A bioengineering manager with 15+ years of experience in DNA sequencing, genetic engineering and Precision Medicine

Profile Summary

A bioengineering manager with 15+ years of experience in development of innovative devices for bioprocess continuous improvements and building of cutting-edge technological platforms for R&D and clinical research in DNA sequencing, genetic engineering, pharmacogenomics and Precision Medicine in France and in Asia. SUMMARY OF QUALIFICATION Developed, industrialized and performed continuous improvement to bioanalytical and technological platforms through process automation, lean management, quality management, efficient project management, risk management, evaluation and transfer of new technologies. Built, trained and led technical and scientific teams to meet stringent accreditation compliance and quality control in regulated environments (GLP/GCLP/HSE/CLIA/CAP/ISO 9001/ISO 15189). Assessed and deployed several Laboratory Information Management System solutions (LIMS) to monitor samples workflow and dataflow, to provide integration with laboratory instruments and applications, to enable electronic data exchanges between the laboratories, Electronic Health Records and ensure compliance with Health Insurance Portability and Accountability Act (HIPAA) and Health Level 7 (HL7). Determined and managed annual funding operating and investment budget, submitted tender requisition for acquisition of new technologies to the board of direction, reviewed tenders proposals evaluation, selected the best proposal that match the tender technical specifications and submitted for approval to the board of direction.

Subject Matter Expertise

• ☆ Biology/Life Sciences
• ☆ Molecular Biology
• ☆ Genetics
• ☆ DNA Sequencing
• ☆ Biotechnology & Bioengineering
• ☆ Biological Engineering
• ☆ Genetic Engineering
• ☆ Precision Medicine
• ☆ Clinical Laboratory Science
• ☆ Product Compliance
• ☆ Risk Management

Services

• Consulting
• Product Development

Work Experience

Teacher in chemical science

Académie de Caen

September 2017 - Present

Physic an Chemistry Secondary School Teacher

Education Nationale Académie de Normandie

February 2017 - Present

Substitute teacher in chemical science

Académie de Caen

February 2017 - August 2017

Manager

Gustave Roussy

September 2013 - December 2013

Laboratory Manager

Genome Institute of Singapore

January 2013 - August 2013

Manager

HELIX2HEALTH PTE. LTD

July 2012 - November 2012

Production Manager

Genome Institute of Singapore

September 2001 - March 2012

Production Team Leader

GENSET. SA

November 1996 - July 2001

Education

Specialized Master (Continuous Improvement and Industrial Performance Management)

Groupe Cesi

October 2015 - January 2016

Diplôme d'Ingénieur - Biological Engineering Design and Innovation of Bio-products

University of Technology of Compiègne

May 2006 - August 2011

Master Degree (Biological Engineering)

Université de Technologie de Compiègne

May 2006 - July 2011

Professional Degree (Industrial Bio experimentation)

Ecole Supérieure des Techniques de Biologie Appliquée

September 1991 - July 1992

Professional Bachelor's Degree in Industrial Bio-experimentation

École Supérieure des Technologies de Biologie Appliquée

August 1991 - June 1992

University of Technology Degree (Applied Biology)

Institut Universitaire de Technologie de Quimper

September 1989 - July 1991

Diplôme Universitaire Technologique in Applied Biology

Institut Universitaire Technologique of QUIMPER

August 1989 - May 1991

Certifications

• Certification details not provided.

Publications

JOURNAL ARTICLE

Fei Yao, Pramila N. Ariyaratne, Axel M. Hillmer, Wah Heng Lee, Guoliang Li, Audrey S. M. Teo, Xing Yi Woo, Zhenshui Zhang, Jieqi P. Chen, Wan Ting Poh, et al.(2012). Long Span {DNA} Paired-End-Tag ({DNA}-{PET}) Sequencing Strategy for the Interrogation of Genomic Structural Mutations and Fusion-Point-Guided Reconstruction of Amplicons . {PLoS} {ONE}. 7. (9). p. e46152. Public Library of Science ({PLoS})

A. M. Hillmer, F. Yao, K. Inaki, W. H. Lee, P. N. Ariyaratne, A. S. M. Teo, X. Y. Woo, Z. Zhang, H. Zhao, L. Ukil, et al.(2011). Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes . Genome Research. 21. (5). p. 665--675. Cold Spring Harbor Laboratory Press

Thoreau Herve, Melissa J. Fullwood, Mei Hui Liu, You Fu Pan, Jun Liu, Han Xu, Yusoff Bin Mohamed, Yuriy L. Orlov, Stoyan Velkov, Andrea Ho, et al.(2009). An oestrogen-receptor-$\upalpha$-bound human chromatin interactome . Nature. 462. (7269). p. 58--64. Springer Nature

Herve Thoreau, Yijun Ruan, Chia Lin Wei, Ai Ee Ling, Vinsensius B Vega, Su Yun Se Thoe, Jer-Ming Chia, Patrick Ng, Kuo Ping Chiu, Landri Lim, et al.(2003). Comparative full-length genome sequence analysis of 14 {SARS} coronavirus isolates and common mutations associated with putative origins of infection . The Lancet. 361. (9371). p. 1779--1785. Elsevier {BV}

Christine Vanhée-Brossollet, Hervé Thoreau, Norberto Serpente, Luc D'Auriol, Jean-Paul Lévy, Catherine Vaquero(1995). A natural antisense {RNA} derived from the {HIV}-1 env gene encodes a protein which is recognized by circulating antibodies of {HIV}$\mathplus$ individuals . Virology. 206. (1). p. 196--202. Elsevier {BV}